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| 1 | 融合性网状乳头瘤病(Gougerot-Carteaud综合征):发病机制中无酵母菌感染证据的美满霉素反应性皮肤病,对39例患者的研究并提出新的诊断标准显示文摘Background: Confluent and reticulate papillomatosis (CRP) (Gougerot-Carteaud syndrome) is a disorder that has been characterized in only small cohorts of patients. Objectives: Better to characterize the clinical and pathological findings of the disorder. Methods: We retrospectively reviewed the clinical presentation, response to treatment and histological findings of patients presenting to Mayo Clinic (Rochester, MN, U.S.A.) with CRP. Results: The disorder was diagnosed in 39 patients between 1972 and 2003. Mean age at onset of the skin eruption was 15 years (range 8-32); 21 patients (54%) were male; most were white; most (33) presented for reasons of cosmesis; and eight described the rash as mildly pruritic. At presentation, the skin eruption had been present for a mean of 3.1 years (range 3 months-20 years) and had been recalcitrant to treatment, including antifungal treatment. Typical objective findings were scaling brown macules and patches and velvety papules and plaques, reticulated and papillomatous at least in part, involving the upper trunk, axillae and neck. The most frequent initial diagnostic impressions were tinea versicolor, acanthosis nigricans and CRP. Scales in 32 cases were examined with potassium hydroxide: eight (25%) showed hyphae, and 24 (75%) did not. Skin biopsy specimens from 21 patients showed variable degrees of hyperkeratosis, acanthosis and papillomatosis. Minocycline was prescribed for 22 patients, of whom 14 of 18 (78%) had complete clearing of the skin eruption and four (22%) a partial response. The skin eruptions recurred after stopping treatment in six patients. Conclusions: CRP occurs predominantly in young adults and teenagers, with cosmetically displeasing brown scaling patches and plaques affecting the neck, upper trunk and axillae. Frequently, the diagnosis is delayed and the disorder not recognized by physicians, including dermatologists. Clinically, the eruption is most often confused with tinea versicolor. Potassium hydroxide staining of the scale is negative in the majority of cases, implying that fungi are not involved in the pathogenesis of this condition, as has been previously proposed. It is important to recognize this disorder, because minocycline therapy is highly effective in most patients. Criteria for the diagnosis are proposed. | Davis M.D.P. Weenig R.H. Camilleri M.J. 吴佳纹 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，2，6： | 2 |
| 2 | Subcutaneous panniculitis-like T-cell lymphoma:an elusive case presenting as lipomembranous panniculitis and a review of 72 cases in the literature显示文摘 | Weenig RH Ng CS Perniciaro C | 2001 | Am J Dermatopathol2001，23，3： | 1 |
| 3 | The impact of lime constraint on information search strategies in complex choice tasks显示文摘 | Weenig M W H Maarleveld M | 2002 | Journal of Economic Psychology2002，，23： | 1 |
| 4 | Subcutaneous panniculitis-like T-cell lymphoma:an elusive case presenting as lipomembranous panni-culitis and a review of 72 cases in the litreature显示文摘 | Weenig RH Ng CS Perniciaro C | 2001 | Dermatopathol2001，23，2： | 1 |
| 5 | Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria显示文摘 | Su WP Davis MD Weenig RH | 2004 | Int J Dermatol2004，43，11： | 1 |
| 6 | Calciphylaxis:natural history,risk factor analysis,and outcome显示文摘 | Weenig RH Sewell LD Davis MD | 2007 | J Am Acad Dermatol2007，56，4： | 1 |
| 7 | The impact oftime constraint on information search strategies in com-plex choice tasks显示文摘 | WEENIG M W H MAA RLEVELD M | 2002 | Journal of Economic Psychology2002，23，： | 1 |
| 8 | Histopathologicfindings in primary erythromelalgia are nonspecific: special studies show a decrease in small nerve fiber density 显示文摘 | Davis MD Weenig RH Genebriera J | 2006 | J Am AcadDermatol2006，55，3： | 1 |
| 9 | Calciphylaxis: natural history, risk factor analysis, and outcome显示文摘 | Weenig RH Sewell LD Davis MD | 2007 | J Am Acad Dermatol2007，56，4： | 1 |
| 10 | Lymphomatoid granulomatosis显示文摘 | Lundell RB Weenig RH Gibson LE | 2008 | Cancer Treat Res2008，142，： | 1 |
| 11 | Subcutaneous pnniculitis-like T-cell lymphoma:an elusive ease presenting as lipomembranous panniculitis and a review of 72 eases in the literature显示文摘 | Weenig RH Ng CS Perniciaro C | 2001 | Am J Dermatopathol2001，23，3： | 1 |
| 12 | Subcutaneous panniculitis-like T-cell lymphoma:an elusive case presenting as lipomembranous panniculitis and a review of 72 cases in the literature显示文摘 | Weenig RH Ng CS Perniciaro C | 2001 | Am J Dermatopathol2001，23，3： | 1 |
| 13 | Pyoderma angrenosum: chinicopatchologic correlation and pfofosed diagnostic criteria 显示文摘 | Su WP Pawis MD Weenig RH | 2004 | Int J Permatol2004，，11： | 1 |
| 14 | Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria显示文摘 | SU W P DAVIS M D WEENIG R H | 2004 | Int J Dermatol2004，43，： | 1 |
| 15 | Subcutaneous panniculitis-like T-cell lymphoma:an elusive case presenting as lipomembranous panniculitis and a review of 72 cases in the literature显示文摘 | Weenig RH Ng CS Perniciaro C | 2001 | Am J Dermatopathol2001，23，3： | 1 |
| 16 | Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria 显示文摘 | Su WP Davis MD Weenig RH | 2004 | Int J Dermatol2004，43，11： | 1 |
| 17 | Skin ulcers misdiagnosed as pyoderma gangrenosum显示文摘 | WEENIG R H DAVIS M D DAHL P R | 2002 | N Engl J Med2002，347，： | 1 |
| 18 | Acne fulminans显示文摘 | Mehrany K Kist JM Weenig RH | 2005 | Int J Dermatol2005，44，2： | 1 |
| 19 | The impact of time con- straint on information search strategies in complex choice tasks 显示文摘 | Weenig M W H Maarleveld M | 2002 | Journal of Economic Psychology2002，23，6： | 1 |
| 20 | The Impact of TimeConstraint on Information Search Strategies in Complex Choice Tasks 显示文摘 | Weenig M W H Maarleveld M | 2002 | Journal of Economic Psychology2002，23，6： | 1 |
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