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| 1 | Comparison between several seismic inversion methods and their application in mountainous coal fields of western China显示文摘With the objective of establishing the necessary conditions for 3D seismic data from mountainous areas in western China, we compared the application results of wave impedance technology in the lithology and exploration of coal fields. First, we introduce principles and features of three kinds of inversion methods. i.e., Model-Based Inversion, Constrained Sparse Spike Inversion (CSSI) and Geology-Seismic Feature Inversion. Secondly, these inversion methods are contrasted in their application to 3D seismic data from some coalfields in western China. The main information provided by the research includes: improving the vertical resolution of coal deposit strata, inferring lateral variation of the lithology and predicting coal seams and their roof lithology. Finally, the comparison between the three methods shows that the model-based inversion has the higher resolution, while CSSI inversion has better waveform continuity. The geology-seismic feature inversion requires information from a large number of wells and many types of logging curves of good quality. All three methods can meet the requirements of seismic exploration for lithological exploration in coal fields. | XU Yongzhong CHEN Tongjun CHEN Shizhong HUANG Weichuan WU Gang | 2010 | Mining Science and Technology2010，20，4： | 9 |
| 2 | Transcriptome profile of human neuroblastoma cells in the hypomagnetic field显示文摘Research has shown that the hypomagnetic field(HMF)can affect embryo development,cell proliferation,learning and memory,and in vitro tubulin assembly.In the present study,we aimed to elucidate the molecular mechanism by which the HMF exerts its effect,by comparing the transcriptome profiles of human neuroblastoma cells exposed to either the HMF or the geomagnetic field.A total of 2464 differentially expressed genes(DEGs)were identified,216 of which were up-regulated and2248 of which were down-regulated after exposure to the HMF.These DEGs were found to be significantly clustered into several key processes,namely macromolecule localization,protein transport,RNA processing,and brain function.Seventeen DEGs were verified by real-time quantitative PCR,and the expression levels of nine of these DEGs were measured every 6 h.Most notably,MAPK1 and CRY2,showed significant up-and down-regulation,respectively,during the first 6 h of HMF exposure,which suggests involvement of the MAPK pathway and cryptochrome in the early bio-HMF response.Our results provide insights into the molecular mechanisms underlying the observed biological effects of the HMF. | MO WeiChuan LIU Ying BARTLETT Perry F HE RongQiao | 2014 | Science China(Life Sciences)2014，57，4： | 8 |
| 3 | Hypomagnetic field,an ignorable environmental factor in space?显示文摘<正>All living organisms on the earth have been exposed to the geomagnetic field(GMF,~50μT),a nature component of the habitability environment,throughout the evolutionary history.However,the environmental magnetic field(MF)in space decreases geometrically with the distance from the ground.The MF magnitude(|B|)at the International Space Station(ISS;near-earth orbit)is similar to the GMF(~80%GMF with limited variation),except that the radial component(Br)exhibits significant variations both in direction and magnitude[1].The environmental MF in outer space is extremely lower than the GMF,called a hypomagnetic field(HMF),e.g.,Martian MF is<5μT,Lunar MF is<300 nT and interplanetary MF is just a few nanotesla[2](Figure 1).Thus,besides micro-gravity(μ-gravity)and cosmic radiation,astronauts have to be exposed and adapt to the HMF condition when onboard in the long-term and long-distance space missions.Even though biological effects of the HMF were | MO WeiChuan LIU Ying HE RongQiao | 2014 | Science China(Life Sciences)2014，57，7： | 5 |
| 4 | Toxic effect of perfluorooctane sulfonate on plants in vertical-flow constructed wetlands显示文摘Per-and polyfluoroalkyl substances(PFASs)can be taken up and bioaccumulated in plants,but the toxic mechanisms of PFASs on wetland plants are still unclear.In present study,the toxic influences of perfluorooctane sulfonate(PFOS)on Eichhornia crassipes(E.crassipes)and Cy perus alternifolius(C.alternifolius)in a vertical-sub surface-flow constructed wetland were evaluated.The results showed that E.crassipes was more tolerant to PFOS stress than C.alternifolius,and the growth and chlorophyll synthesis of the two plants were promoted by low concentration(<0.1 mg/L)of PFOS,and the chlorophyll synthesis was inhibited by high concentration(10 mg/L)of PFOS but the growth did not change obviously.The catalase activity and malondialdehyde content in the leaves of the two plants increased,peroxidase activity decreased under exposure to high concentrations of PFOS,and superoxide dismutase activity did not change.Under PFOS stress,the membrane of plant leaves and the cell structure of the two wetland plants were destroyed,and the mitochondrial contour of root cells became incomplete.Tanscriptomic analysis showed that the expression levels of genes related to cell wall formation,the cell apoptosis pathway,material synthesis,and metabolism in the plants were changed by PFOS.Analysis in fluorogenic quantitative real time polymerase chain reaction(RT-qPCR)also confirmed that the photosynthesis system of E.crassipes was inhibited,while that of C.alternifolius was promoted. | Rong Li Tianhao Tang Weichuan Qiao Jun Huang | 2020 | Journal of Environmental Sciences2020，32，6： | 3 |
| 5 | Bio-inspired synthesis of nanomaterials and smart structures for electrochemical energy storage and conversion显示文摘Traditional synthetic methodologies are confronted with great challenges to fabricate complex nanomaterials with delicate design,high efficiency and excellent sustainability.During the past decade,bio-inspired synthesis has been extensively applied as an effective and efficient strategy for the fabrication of nanomaterials and nanostructures.Mimicking electrode materials at nanoscale in the aspect of either structure or functionality has been receiving surging interest because of their incomparable advantages and outperforming properties.In this review,we summarize the recent progresses on bio-inspired synthesis of nanomaterials and smart structures in the field of energy storage and conversion.Firstly,an overall introduction of bio-inspired synthetic strategies will be presented,with focus on the biotemplates and bio-resources.Following that,a library of complex mimicking structures featured by high-order,hierarchical porosity,or bionic function are introduced,with discussion on their chemical and physical properties associated with the structure.The enhanced electrochemical properties such as energy density,cycling stability,etc.in different electrochemical systems will be also discussed.At last,we will expand the perspectives regarding the advantages and limitations of bioinspired strategy and possible solutions in the future. | Mei Ding Gen Chen Weichuan Xu Chuankun Jia Hongmei Luo | 2020 | Nano Materials Science2020，2，3： | 3 |
| 6 | Removal,distribution and plant uptake of perfluorooctane sulfonate(PFOS)in a simulated constructed wetland system显示文摘A vertical-flow constructed wetland(VFCW)was used to treat simulated domestic sewage containing perfluorooctane sulfonate(PFOS).The removal rate of PFOS in the domestic sewage was 93%–98%,through soil adsorption and plant uptake,suggesting that VFCWs can remove PFOS efficiently from wastewater.The removal of PFOS in the VFCW was dependent on soil adsorption and plant uptake;moreover,the percentage of soil adsorption was 61%–89%,and was higher than that of the plants uptake(5%–31%).The absorption capacity of Eichhornia crassipes(E.crassipes)(1186.71 mg/kg)was higher than that of Cyperus alternifolius(C.alternifolius)(162.77 mg/kg)under 10 mg/L PFOS,and the transfer factor of PFOS in E.crassipes and C.alternifolius was 0.04 and 0.58,respectively,indicating that PFOS is not easily translocated to leaves from roots of wetland plants;moreover,uptake of PFOS by E.crassipes was more than that of C.alternifolius because the biomass of E.crassipes was more than that of C.alternifolius and the roots of E.crassipes can take up PFOS directly from wastewater while C.alternifolius needs to do so via its roots in the soil.The concentration of 10 mg/L PFOS had an obvious inhibitory effect on the removal rate of total nitrogen,total phosphorus,chemical oxygen demand,and ammonia nitrogen in the VFCW,which decreased by 15%,10%,10%and 12%,respectively.Dosing with PFOS in the wastewater reduced the bacterial richness but increased the diversity in soil because PFOS stimulated the growth of PFOS-tolerant strains. | Weichuan Qiao Rong Li Tianhao Tang Achuo Anitta Zuh | 2021 | Frontiers of Environmental Science & Engineering2021，15，2： | 3 |
| 7 | Study on Mt control method of friction welding显示文摘A new type control method in friction welding is suggested in this pa-per,that is compositive control method of friction torque and friction time,itcalled Mt control method for short.The principle of Mt control method and itsfeature are concisely explained. | Wang Shiyuan Qiu Fengxiang Zhang Guifeng Xi’an Jiaotong University,Xi’an Chang Weichuan Nanjing Automobile Manufacturing Plant,Nanjing | 1992 | China Welding1992，2，2： | 2 |
| 8 | Engineered human pluripotent stem cell-derived natural killer cells with PD-L1 responsive immunological memory for enhanced immunotherapeutic efficacy显示文摘Adoptive chimeric antigen receptor(CAR)-engineered natural killer(NK)cells have shown promise in treating various cancers.However,limited immunological memory and access to sufficient numbers of allogenic donor cells have hindered their broader preclinical and clinical applications.Here,we first assess eight different CAR constructs that use an anti-PD-L1 nanobody and/or universal anti-fluorescein(FITC)single-chain variable fragment(scFv)to enhance antigen-specific proliferation and anti-tumor cytotoxicity of NK-92 cells against heterogenous solid tumors.We next genetically engineer human pluripotent stem cells(hPSCs)with optimized CARs and differentiate them into functional dual CAR-NK cells.The tumor microenvironment responsive anti-PD-L1 CAR effectively promoted hPSC-NK cell proliferation and cytotoxicity through antigen-dependent activation of phosphorylated STAT3(pSTAT3)and pSTAT5 signaling pathways via an intracellular truncated IL-2 receptorβ-chain(ΔIL-2Rβ)and STAT3-binding tyrosine-X-X-glutamine(YXXQ)motif.Anti-tumor activities of PD-L1-induced memory-like hPSC-NK cells were further boosted by administering a FITC-folate bi-specific adapter that bridges between a programmable anti-FITC CAR and folate receptor alpha-expressing breast tumor cells.Collectively,our hPSC CAR-NK engineering platform is modular and could constitute a realistic strategy to manufacture off-the-shelf CAR-NK cells with immunological memory-like phenotype for targeted immunotherapy. | Yun Chang Gyuhyung Jin Weichuan Luo Qian Luo Juhyung Jung Sydney N.Hummel Sandra Torregrosa-Allen Bennett D.Elzey Philip S.Low Xiaojun Lance Lian Xiaoping Bao | 2023 | Bioactive Materials2023，，9： | 2 |
| 9 | Comparison of public peak detection algorithms for MALDI mass spectrometry data analysis显示文摘 | Yang Chao He Zengyou Yu Weichuan | 2009 | BMC Bioinformatics2009，10，4： | 1 |
| 10 | Comparison of public peak detection algorithms for MALDI mass spectrometry data analysis 显示文摘 | Yang Chao He Zengyou Yu Weichuan | 2009 | BMC Bioinformatics2009，10，4： | 1 |
| 11 | Noise-robust edge detector com- bining isotropic and anisotropic Gaussian kernels 显示文摘 | Shui Penglang Zhang Weichuan | 2012 | Pattern Recognition2012，45，2： | 1 |
| 12 | Oralinoculation of probiotics Lactobacillus acidophilus NCFM sup-presses tumour growth both in segmental orthotopic colon cancerand extra-intestinal tissue 显示文摘 | Chen Chienchang Lin Weichuan Kong Manshan | 2012 | British Journal of Nutrition2012，107，11： | 1 |
| 13 | Adaptive color feature extraction based on image color distributions显示文摘 | CHEN Weita LIU Weichuan CHEN M S | 2010 | IEEETrans on Image Processing2010，19，8： | 1 |
| 14 | Enhanced undeeylprodigiosin production from Serratia marcescens SS-1 by medium formulation and amino acid supplementation显示文摘 | Wei Yuhong Yu wanju Chen Weichuan | 2005 | Journal of Bioscience and Bioengineering2005，100，4： | 1 |
| 15 | Uniqueness theorems for meromorphic functions that share three sets显示文摘 | Lin Weichuan Yi Hongxun | | 0，，： | 1 |
| 16 | Combinative multi-scale level set framework for echocardiographic image segmentation显示文摘 | Ning L Weichuan Y James S D | 2004 | Medical Image Analysis2004，7，4： | 1 |
| 17 | Combinative multi-scale level set framework for echocardiographic image segmentation显示文摘 | LIN Ning YU Weichuan DUNCAN J S | | 0，，4： | 1 |
| 18 | On a new singular direction of meromorphie functions 显示文摘 | L in Weichuan Seiki Moil | 2006 | Complex Variables and Elliptic Equations2006，51，4： | 1 |
| 19 | Uniqueness theorems for meromorphic function concerning fixed-points显示文摘 | Lin Weichuan Yi Hongxun | 2004 | Complex Vaniables2004，49，11： | 1 |
| 20 | ClosedcircleDNAalgorithmforSATproblem显示文摘 | ZHOUKang WEIChuanjia LIUShuo etal | 2009 | JournalofHuazhongUniversityofScienceandTechnologh2009，37，7： | 1 |
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