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96篇 您的检索式:作者名="Weisleder"
    题名 作者 年代 出处 被引量
1Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals显示文摘线粒体为精力新陈代谢和反应的氧种类(ROS ) 的生产是必要的。在未经触动的房间,呼吸线粒体展览自发的 “ superoxide flashes”,对短暂 mitochondrial 渗透转变(tMPT ) 结果的 quantal 生产 ROS 事件。这里,我们在表示 superoxide 生物传感器 mt-cpYFP 的生活老鼠在 mitochondrial superoxide 闪光和 tMPT 活动的 vivo 成像执行第一,并且表明他们联合到整个身体的葡萄糖新陈代谢。柔韧的 tMPT/superoxide 闪光活动发生在骨胳的肌肉和 anesthetized 的臀部的神经转基因的老鼠。在骨胳的肌肉,成像 tMPT/superoxide 闪光揭示了线粒体的迷宫的三维的网络同时地操作。tMPT/superoxide 闪光活动响应全身的葡萄糖挑战或胰岛素刺激澎湃,以一种显然调制频率的方式并且也在 tMPT 的 gating 模式包含移动。因此,在 tMPT 依赖的 mitochondrial ROS 的 vivo 成像,信号和 metabolism-tMPT-superoxide 的发现闪光联合标记为 mitochondrial 功能并且 ROS 处于健康和疾病发信号的学习的重要工艺、概念的进展。Huaqiang Fang Min Chen Yi Ding Wei Shang Jiejia Xu Xing Zhang Wanrui Zhang Kaitao Li Yao Xiao Feng Gao Shujiang Shang Jing-Chao Li Xiao-Li Tian Shi-Qiang Wang Jingsong Zhou Noah Weisleder Jianjie Ma Kunfu Ouyang Ju Chen Xianhua Wang Ming Zheng Wang Wang Xiuqin Zhang Heping Cheng 2011Cell Research2011,21,9:11
2Treflorine,trenudine,and N-methyltrewiasine:novel maytansinoid tumor inhibitors containing two fused macrocyclic rings显示文摘Powell RG Weisleder D Smith CR Jr 1982J Am Chem Soc1982,104,18:1
3Linustatin and neolinustatin: cyanogenic glycosides of linseed meal that protect animals against selenium toxic- ity显示文摘Smith C R D Weisleder R W Miller 1980JOrgChem1980,45,:1
4SES differences in language processing skill and vocabulary are evident at 18 months显示文摘Fernald A Marchman VA Weisleder A 2013Dev Sci2013,16,2:1
5A nematicidal toxin from Pleurotus ostreatus NRRL 3526显示文摘Kwok O C H Plattner R Weisleder D 1992J Chem Ecol1992,18,2:1
6A new fumonisin from solid cultures of fusarium moniliforme 显示文摘Plattner R D Weisleder D Shackelford D D 1992Mycopathologia1992,117,12:1
7MG53 nucleates as- sembly of cell membrane repair machinery显示文摘Cai C Masumiya H Weisleder N 2009Nat Cell Biol2009,11,1:1
8NMR Investi- gations of rotenoids 显示文摘Carison D G Weisleder D Tallent W H 1973Tetrahedron1973,29,18:1
9Mitsugumin 53 ( MG53 ) facilitates vesicle trafficking in striated muscle to contribute to cell membrane repair 显示文摘Weisleder N Takeshima H Ma J 2009Commun Integr Biol2009,2,3:1
10MG53 constitutes a primary determinant of cardiac ischemic preconditioning 显示文摘Cao C M Zhang Y Weisleder N 2010Circulation2010,121,23:1
11Oxygenated fatty ac- ids of isano oil显示文摘Miller R W Weisleder D Kleiman R 1977Phytochemistry1977,16,7:1
12Identification of hair ceil progenitors and intermitotic migration of their nuclei in the normal and regenerating avian inner ear显示文摘Tsue TT Watling DL Weisleder P 1994J Neuroscience1994,14,:1
13Linustatin and neolinustatin:cyanogenic glycosides of linseed meal that protect animals against selenium toxicity 显示文摘Smith CR Weisleder JD Miller RW 1980J Org Chem1980,45,3:1
14A nematicidal toxin from Pleurotus ostreatus NRRL 3526显示文摘Kwork O C H Plattner R Weisleder D 1992J Chem Ecol1992,18,2:1
15Novel maytansinoid tumor inhibitors from Trewia mudiflora:trewiasine,dehydrotrewiasine,and demethyltrewiasine显示文摘Powell R G Weisleder D Smith C R 1981J Org Chem1981,46,22:1
16Novel maytansinoid tumor inhibitors from Trewia nudiflora : trewiasine, dehydrotrewiasine and demethyltrewiasine 显示文摘Powell RG Weisleder D Smith CR 1981Journal Organic Chemistry1981,46,22:1
17Treflorine,trenudine,and N-methyltrenudone:novel maytansinoid tumor inhibitors containing two fused macrocyclic rings显示文摘Powell R G Weisleder D Smith C R 1982J Am Chem Soc1982,104,18:1
18A nematicidal toxin from Pleurotus ostreatus NRRL 3526 显示文摘Kwork O C H Plattner R Weisleder D 1992Journal of Chemical Ecology1992,18,:1
19Antitumor alkaloids from Cephalotaxus harringtonia: Structure and activity 显示文摘Powell R G Weislede D Smith C R 1972J Pharm Sci1972,61,8:1
20Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy显示文摘Weisleder N Taffet GE Capetanaki Y 2004Proc Natl Acad Sci USA2004,101,3:1
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