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| 1 | Multi-UAV reconnaissance task allocation for heterogeneous targets using an opposition-based genetic algorithm with double-chromosome encoding显示文摘This paper presents a novel multiple Unmanned Aerial Vehicles(UAVs) reconnaissance task allocation model for heterogeneous targets and an effective genetic algorithm to optimize UAVs' task sequence. Heterogeneous targets are classified into point targets, line targets and area targets according to features of target geometry and sensor's field of view. Each UAV is regarded as a Dubins vehicle to consider the kinematic constraints. And the objective of task allocation is to minimize the task execution time and UAVs' total consumptions. Then, multi-UAV reconnaissance task allocation is formulated as an extended Multiple Dubins Travelling Salesmen Problem(MDTSP), where visit paths to the heterogeneous targets must meet specific constraints due to the targets' feature. As a complex combinatorial optimization problem, the dimensions of MDTSP are further increased due to the heterogeneity of targets. To efficiently solve this computationally expensive problem, the Opposition-based Genetic Algorithm using Double-chromosomes Encoding and Multiple Mutation Operators(OGA-DEMMO) is developed to improve the population variety for enhancing the global exploration capability. The simulation results demonstrate that OGADEMMO outperforms the ordinary genetic algorithm, ant colony optimization and random search in terms of optimality of the allocation results, especially for large scale reconnaissance task allocation problems. | Zhu WANG Li LIU Teng LONG Yonglu WENa | 2018 | Chinese Journal of Aeronautics2018，31，2： | 35 |
| 2 | The design and synthesis of dextran-doxorubicin prodrug-based pH-sensitive drug delivery system for improving chemotherapy efficacy显示文摘Tumor cells show acidic conditions compared with normal cells,which further inspires scientist to build nanocarrier responsive to tumor microenvironment(TME)for enhancing tumor therapeutic efficacy.Here,we report a pH-sensitive and biocompatible polyprodrug based on dextran-doxorubicin(DOX)prodrug(DOXDT)for enhanced chemotherapy.Highdensity DOX component was covalently decorated on the nanocarrier and the drug molecules could be effectively released in the acidic tumor tissue/cells,improving chemotherapy efficacy.Specifically,a dextran-based copolymer was preliminarily prepared by one-step atom transfer radical polymerization(ATRP);then DOX was conjugated on the copolymer component via pH-responsive hydrazone bond.The structure of DOXDT can be well-controlled.The resulting DOXDT was able to further self-assemble into nanoscale micelles with a hydration diameter of about 32.4 nm,which presented excellent micellar stability.Compared to lipid-based drug delivery system,the DOXDT prodrug showed higher drug load capacity up to 23.6%.In addition,excellent stability and smaller size of the nanocarrier contributed to better tissue permeability and tumor suppressive effects in vivo.Hence,this amphipathic DOXDT prodrug is promising in the development of translational DOX formulations,which would be widely applied in cancer therapy. | Xiaoli Zhang Tian Zhang Xianbin Ma Yajun Wang Yi Lu Die Jia Xiaohua Huang Jiucun Chen Zhigang Xu Feiqiu Wena | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，5： | 3 |
| 3 | The effect of DMPA units on ionic conductivity of PEG-DMPA-IPDI waterborne polyurethane as single-ion electrolytes显示文摘 | Ten-Chin Wena Yeong-Jyh Wanga Tsung-Tien Chenga | 1999 | Polymer1999，40，： | 1 |
| 4 | Inversion of dy- namic production data for permeability:Fast streamline-based computation of sensitivity coefficients of fractional flow rate 显示文摘 | Wena X H Deutsch C V Cullick A S | 2003 | Journal of Hydrology2003，281，： | 1 |
| 5 | Carbonaceous sulfur- containing chitosan Fe( m ) :a novel adsorbent for efficient removal of copper ( U ) from water 显示文摘 | WENA Y Z MAA J Q CHENA J | 2015 | Chemical Engineering Journal2015，259，： | 1 |
| 6 | Carrier transport in hight-efficiency of ZnO/SiO2/Si solar cells 显示文摘 | Wilson W Wenas Syarif Riyadi | 2006 | Solar Energy Materials and Solar Cells2006，90，1819： | 1 |
| 7 | GinsenosideRdimprovesoutcomeofacuteischaemicstroke:arandomized,double-blind,placebo-controlled,multicentertrial显示文摘 | LiuX WangL WenA etal | 2012 | EuropJNeurol2012，19，： | 1 |
| 8 | Extraction of geometric characteristics for manufacturability assessment显示文摘 | Yuh-Min Chena Chiun-Cheng Wena Chengter Ted Ho | 2003 | Robotics and Computer Integrated Manufacturing2003，19，4： | 1 |
| 9 | A reproducible experimental model of focal cerebral ischemia in the neonatal rat 显示文摘 | Tong-Chun Wena Marta Rogidoa Pierre Gressensb | 2004 | Brain Research Protocols2004，13，： | 1 |
| 10 | Pricing policies for substitutable products in a supply Chain with Internet and traditional channels显示文摘 | Chen Yanchu Fang S C Wena U P | 2013 | European Journal of Opera-tional Research2013，224，3： | 1 |
| 11 | Carrier transport in high-efficiency ZnO/SiO2/Si solar cells显示文摘 | Wenas W W Riyadi S | 2006 | Solar Energy Materials & Solar Cells2006，90，1819： | 1 |
| 12 | Electricaland optical properties of boron-doped ZnO thin filmsfor solar cells grown by metalorganic chemical vapordeposition显示文摘 | Wenas W W Yamada A Takahashi K | 1991 | J Appl Phys1991，70，： | 1 |
| 13 | Large-areaZnO thin films for solar cells prepared byphoto-induced metal organic chemical vapor deposition显示文摘 | Yoshino M Wenas W W Yamada A | 1993 | Jpn J Appl Phys1993，32，： | 1 |
| 14 | Pigmentde villonodular synovitis:keys to early diagnosis显示文摘 | Bhimani MA Wena JF Frassica Fj | 2001 | Clin Orthop2001，386，2： | 1 |
| 15 | The effect of DMPA units on ionic conductivity of PEG-DMPA-IPDI waterborne polyurethane as single-ion electrolytes显示文摘 | TEN-CHIN WENA YEONG-JYH WANG | 1999 | Polymer1999，40，： | 1 |
| 16 | An image encryption algo- rithm based on scrambling and chaos 显示文摘 | Wena C Wanga Q Liub X | 2013 | Joumal of Information & Computational Science2013，17，10： | 1 |
| 17 | Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes显示文摘 | Shu Wu Wena Chen Elizabeth Murphy | 1997 | J Biol Chem1997，272，12： | 1 |
| 18 | optimization of Zno for front and rearcontacts in a-Si solar cells 显示文摘 | Wenas W W | 1994 | Solar Energy Materials andSolar Cells1994，34，： | 1 |
| 19 | Textured ZnO Thin Films for Solar Cells Grown by Metalorganic Chemical Vapor Deposition显示文摘 | Akira Yamada A Makoto Konagai | 1991 | Japanese Journal of Applied Physics1991，30，3： | 1 |
| 20 | Large-area ZnO Thin Films for Solar Cells Prepared by Photo-induced Metalorganic Chemical Vapor Deposition 显示文摘 | Masahiro Yoshino Wilson Wenas W Akira Yamada | 1993 | Japanese Journal of Applied Physics1993，32，： | 1 |
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