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5篇 您的检索式:作者名="Westmeyer G"
    题名 作者 年代 出处 被引量
1Functional optoacoustic neuro-tomography for scalable whole-brain monitoring of calcium indicators显示文摘Non-invasive observation of spatiotemporal activity of large neural populations distributed over entire brains is a longstanding goal of neuroscience.We developed a volumetric multispectral optoacoustic tomography platform for imaging neural activation deep in scattering brains.It can record 100 volumetric frames per second across scalable fields of view ranging between 50 and 1000 mm^(3) with respective spatial resolution of 35–200μm.Experiments performed in immobilized and freely swimming larvae and in adult zebrafish brains expressing the genetically encoded calcium indicator GCaMP5G demonstrate,for the first time,the fundamental ability to directly track neural dynamics using optoacoustics while overcoming the longstanding penetration barrier of optical imaging in scattering brains.The newly developed platform thus offers unprecedented capabilities for functional whole-brain observations of fast calcium dynamics;in combination with optoacoustics'well-established capacity for resolving vascular hemodynamics,it could open new vistas in the study of neural activity and neurovascular coupling in health and disease.X Luís Deán-Ben Gali Sela Antonella Lauri Moritz Kneipp Vasilis Ntziachristos Gil G Westmeyer Shy Shoham Daniel Razansky 2016Light(Science & Applications)2016,5,1:5
2Directed evolution of a magnetic resonance ima- ging contrast agent for noninvasive imaging of dopa- mine显示文摘SHAPIRO M G WESTMEYER G G ROMERO P A 2010Nat Biotech2010,28,3:1
3A non-amyloidogenic function of BACE-2 in the secretory pathway显示文摘Fluhrer R Capell A Westmeyer G 2002J Neurochem2002,81,5:1
4Genetically Controlled MRI Contrast Mechanisms and Their Prospects in Systems Neuroscience Research显示文摘Westmeyer G G Jasanoff A 2007Magnetic Resonance Imaging2007,25,6:1
5A non-amyloid ogenic function of BACE-2 in the secretory pathway显示文摘Fluhrer R Capell A Westmeyer G 2005J Neurochem2005,81,5:1
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