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| 1 | Psychosocial mechanisms for the transmission of somatic symptoms from parents to children显示文摘AIM: To examine familial aggregation of irritable bowel syndrome(IBS) via parental reinforcement/modeling of symptoms, coping, psychological distress, and exposure to stress.METHODS:Mothers of children between the ages of8 and 15 years with and without IBS were identified through the Group Health Cooperative of Puget Sound.Mothers completed questionnaires,including the Child Behavior Checklist(child psychological distress),the Family Inventory of Life Events(family exposure to stress),SCL-90R(mother psychological distress),and the Pain Response Inventory(beliefs about pain).Children were interviewed separately from their parents and completed the Pain Beliefs Questionnaire(beliefs about pain),Pain Response Inventory(coping)and Child Symptom Checklist[gastrointestinal(GI)symptoms].In addition,health care utilization data was obtained from the automated database of Group Health Cooperative.Mothers with IBS(n=207)and their 296 children were compared to 240 control mothers and their 335 children,while controlling for age and education.RESULTS:Hypothesis 1:reinforcement of expression of GI problems is only related to GI symptoms,but not others(cold symptoms)in children.There was no significant correlation between parental reinforcement of symptoms and child expression of GI or other symptoms.Hypothesis 2:modeling of GI symptomsis related to GI but not non-GI symptom reporting in children.Children of parents with IBS reported more non-GI(8.97 vs 6.70,P<0.01)as well as more GI(3.24 vs 2.27,P<0.01)symptoms.Total health care visits made by the mother correlated with visits made by the child(rho=0.35,P<0.001 for cases,rho=0.26,P<0.001 for controls).Hypothesis 3:children learn to share the methods of coping with illness that their mothers exhibit.Methods used by children to cope with stomachaches differed from methods used by their mothers.Only 2/16 scales showed weak but significant correlations(stoicism rho=0.13,P<0.05;acceptance rho=0.13,P<0.05).Hypothesis 4:mothers and children share psychological traits such as anxiety,depression,and somatization.Child psychological distress correlated with mother’s psychological distress(rho=0.41,P<0.001 for cases,rho=0.38,P<0.001 for controls).Hypothesis 5:stress that affects the whole family might explain the similarities between mothers and their children.Family exposure to stress was not a significant predictor of children’s symptom reports.Hypothesis 6:the intergenerational transmission of GI illness behavior may be due to multiple mechanisms.Regression analysis identified multiple independent predictors of the child’s GI complaints,which were similar to the predictors of the child’s non-GI symptoms(mother’s IBS status,child psychological symptoms,child catastrophizing,and child age).CONCLUSION:Multiple factors influence the reporting of children’s gastrointestinal and non-gastrointestinal symptoms.The clustering of illness within families is best understood using a model that incorporates all these factors. | Miranda AL van Tilburg Rona L Levy Lynn S Walker Michael Von Korff Lauren D Feld Michelle Garner Andrew D Feld William E Whitehead | 2015 | World Journal of Gastroenterology2015,21,18: | 2 |
| 2 | Social learning contributions to the etiology and treatment of functional abdominal pain and inflammatory bowel disease in children and adults显示文摘This paper reviews empirical work on cognitive and social learning contributions to the etiology and treatment of illness behavior associated with functional abdominal pain and inflammatory bowel disease. A particular emphasis is placed on randomized controlled trials, the majority of which are multi-modal in orientation, incorporating elements of cognitive behavioral therapy, social learning, and relaxation. Based on this review, we offer methodological and clinical suggestions: (1) Research investigations should include adequate sample sizes, long-term follow-up assessments, and a credible, active control group. (2) Standard gastrointestinal practice should include, when appropriate, learning opportunities for patients and family members, for example, instruction regarding the encouragement of wellness behavior. | Rona L Levy Shelby L Langer William E Whitehead | 2007 | World Journal of Gastroenterology2007,13,17: | 2 |
| 3 | Association of cardiovascular system medications with cognitive function and dementia in older adults living in nursing homes in Australia显示文摘ObjectiveTo 在在检验生活和资源使用的质量的 17 所澳大利亚的疗养院的代表性的研究的 Australia.MethodsAs 部分住在疗养院的更老的成年人与认知功能和痴呆的诊断检验在心血管的系统药使用之间的协会,我们检验了在认知缺陷和心血管的药使用之间的协会(使用解剖治疗学的分类系统识别)用一般线性回归和逻辑 regressio 正在收到生活照顾的结束的人是包括的 excluded.ResultsParticipants 有一个平均数的 541 个居民 85.5 | Enwu Liu Suzanne M Dyer Lisa Kouladjian O'Donnell Rachel Milte Clare Bradley Stephanie L Harrison Emmanuel Gnanamanickam Craig Whitehead Maria Crotty | 2017 | Journal of Geriatric Cardiology2017,14,6: | 2 |
| 4 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004,101,26: | 1 |
| 5 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998,393,: | 1 |
| 6 | Chromatic uniqueness and equivalence of k4 homeomorphs 显示文摘 | Whitehead E G Zhao L C | 1984 | J Graph Theory1984,,8: | 1 |
| 7 | Ventilator-associated lung injury显示文摘 | Pinhu L Whitehead T Evans T | 2003 | Lancet2003,361,9354: | 1 |
| 8 | 测定红茶茶红素和茶黄素的快速方法显示文摘本文描述了用成本低廉的小型C_(18)药筒快速分离和测定红茶茶汤中茶红素和茶黄素的常规方法。传统方法分析速度慢,而且,由于黄酮醇糖苷的干扰,茶红素的测定结果往往偏高。本文也将药筒法与其它测定茶黄素和茶红素的方法进行了比较。 | David L Whitehead 莫治雄 | 1994 | 广东茶叶1994,,2: | 1 |
| 9 | Chromatic uniqueness and equivalence of K4 -homeomorphs 显示文摘 | WHITEHEAD JR E G ZHAO L C | 1984 | J Graph Theory1984,8,: | 1 |
| 10 | Ventilator-associated lung injury 显示文摘 | Pinhu L Whitehead T Evans T | 2003 | Lancet2003,361,9354: | 1 |
| 11 | Molec-ular genetic evidence for the involvement of a specificpolygalacturonase,P2c,in the invasion and spread ofAspergillus flavus in cotton bolls显示文摘 | Shieh M T Brown R L Whitehead M P | 1997 | Applied andEnvironmental Microbiology1997,63,9: | 1 |
| 12 | Ventilator-associated lung injury显示文摘 | Pinhu L Whitehead T Evans T | 2003 | Lancet2003,361,: | 1 |
| 13 | Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of L1M 1215 colon cancer cells 显示文摘 | Leng S L Leeding K S Whitehead R H | 2001 | Molecular and Cellular Endocrinology2001,174,12: | 1 |
| 14 | Amoxycillin release from a floating dosage form based on alginates显示文摘 | Whitehead L Collett JH Fell JT | 2000 | Int J Pharm2000,210,12: | 1 |
| 15 | High vita- min D3 requirements in broilers for bone quality and preven- tion of tibialdyschondrplasia and interactions with dietary calcium available phosphorous and vitamin A显示文摘 | Whitehead C C Mccormack H A McTier L | 2004 | British Poultry Science2004,45,: | 1 |
| 16 | Symptoms of psychologic distress associated with irritable bowel syndrome: Comparimn of comnxaaity and medical clinic samples 显示文摘 | Whitehead W E Bosmjian L Zonderment A B | 1998 | Gastroenterology1998,95,: | 1 |
| 17 | Measurement of otoacoustic emissions for hearing assessment显示文摘 | WHITEHEAD L STAGNER B B LONSBURY-MARTIN B L | 1994 | IEEE Engineering in Medical and Biology1994,13,2: | 1 |
| 18 | Relation of pregnancy and neonatal factors to subsequent development of childhood epilepsy: a population-based cohort study显示文摘 | Whitehead E Dodds L Joseph KS | 2006 | Pediatrics2006,117,4: | 1 |
| 19 | Evaluation of biomarker panels for early stage ovarian cancer detection and monitoring for disease recurrence 显示文摘 | Havrilesky L J Whitehead C M Rubatt J M | 2008 | Gynecol Oncol2008,110,3: | 1 |
| 20 | Numbers of Salmonella enteritidis in the contents of naturally contaminated hens' eggs显示文摘 | Humphrey T J Whitehead A Gawler A H L | 1991 | Epidemiol Infection1991,106,: | 1 |