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58篇 您的检索式:作者名="Wilbert J"
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1Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno-or squamous cell carcinoma显示文摘AIM:To determine whether-1195 A→G and/or-765 G→C polymorphisms in Cyclooxygenase-2(COX-2 ) may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population.METHODS:Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area.DNA was isolated from whole blood and used for genotyping.PCR products were digested with restriction enzymes and products were analyzed by agarose gel electrophoresis.Odds ratios(OR) and 95% confldence intervals(CI) were estimated.RESULTS:The distribution of the-1195 A→G polymorphism was signif icantly different in esophageal cancer patients compared to controls.The-1195 GG genotype resulted in a higher risk of developing esophageal adenocarcinoma(OR = 3.85, 95% CI:1.45-10.3) compared with the-1195 AA genotype as a reference.The-765 G→C genotype distribution was not different between the two groups.The GG/ GG haplotype was present more often in esophageal adenocarcinoma patients than in controls(OR = 3.45, 95% CI:1.24-9.58;with AG/AG as a reference).The same trends were observed in patients with squamous cell carcinomas, however, the results did not reach statistical signif icance.CONCLUSION:Presence of the COX-2-1195 GG genotype and of the GG/GG haplotype may result in a higher risk of developing esophageal carcinoma.Jón O Kristinsson Paul van Westerveld Rene HM te Morsche Hennie MJ Roelofs T Wobbes Ben JM Witteman Adriaan CITL Tan Martijn GH van Oijen Jan BMJ Jansen Wilbert HM Peters 2009World Journal of Gastroenterology2009,15,28:11
2Positioning accuracy of cone-beam computed tomography in combination with a HexaPOD robot treat- ment table显示文摘Meyer J Wilbert J Baier K 2007Int J Radiat Oncol Biol Phys2007,67,:1
3Intra-fractional uncertainties in cone-beam CT based image-guided radiotherapy (IGRT) of pulmonary tumors 显示文摘Guckenberger M Meyer J Wilbert J 2007Radiother Oncol2007,83,1:1
4Precision of image-guided radiotherapy (IGRT) in six degrees of freedom and limitations in clinical practice显示文摘GUCKENBERGER M MEYER J WILBERT J 2007Strahlentherapie und Onkologie2007,183,6:1
5Positioning accuracy of cone-beam computed tomography in combination with a HexaPOD robot treatment table显示文摘Meyer J Wilbert J Baier K 2007Int J Radiat Oncol B iol Phys2007,67,:1
6Cardiacamyloidosis approaches to diagnosis and management 显示文摘Desai H Wilbert S Stephen J 2010Cardiol Rev2010,18,1:1
7Potential of adaptive radiotherapy to escalate the radiation dose in combined radiochemotberapy for locally advanced non-small cell lung cancer显示文摘Guckenberger M Wilbert J Richter A 2011Int J Radiat Oncol Biol Phys2011,79,3:1
8Precision of image -guided radiotherapy (IGRT) in six degrees of freedom and limita-tion in clinical practice 显示文摘Guckenbei^er M Meyer J Wilbert J 2007Strahlenther Onkol2007,183,:1
9Adaptive radiotherapy for locally advanced non-small-cell lung cancer does not underdose the microscopic disease and has the potential to increase tumor control显示文摘Guckenberger M Richter A Wilbert J 0,,04:1
10Cardiac amyloidosis approaches to diagnosis and management显示文摘DESAI H WILBERT S STEPHEN J 2010Cardiol Rev2010,18,:1
11Intra-fractional uncertainties in cone-beam CT based image-guided radiotherapy (IGRT) of pulmonary tumors显示文摘Guckenberger M Meyer J Wilbert J 2007Radiother Oncol2007,83,1:1
12The use of tween 20 as a blocking agent in the immu- nological detection of proteins transferred to nitrocellu- lose membranes 显示文摘BATFEIGER B WILBERT J NEWHALL V 1982Journal of Immunology Methods1982,55,3:1
13Operational performance of the TIMED doppler interferometer (TIDI) 显示文摘WILBERT R S RICK J N TIMOTHY L K 2003Proceedings of SPIE2003,5175,:1
14A Method for Assessing Thermal Comfort of Shoes Using a 'Sweating'Foot 显示文摘Ed H M Schols Wilbert A J van den Eijnde Ronald Heus 2004European journal of applied physiology2004,92,6:1
15Clinical outcome of dose-escalated image-guided radiotherapy for spinal metasta- ses显示文摘Guckenberger M Goebel J Wilbert J 2009Int J Radiat Oncol Biol Phys2009,75,:1
16Potential of adaptive radiotherapy to escalate the radiation dose in combined radiochemotherapy for locally advanced non-small cell lung cancer显示文摘Guckenberger M Wilbert J Richter A 2011Int J Radiat Oncol Biol Phys2011,79,3:1
17Bench-scale testing of surfactant-modified reverse osmosis/nanofiltration membranes 显示文摘Wilbert M C Pellegrino J Zydney A 1998Desalination1998,115,1:1
18Adaptive radiotherapy for locally advanced non-small-cell lung cancer does not underdose the microscopic disease and has the potential to increase tumor control显示文摘Guckenberger M Richter A Wilbert J 2011Int J Radiat Oncol Biol Phys2011,81,4:1
19Precision of imageguided radiotherapy (IGRT) in six degrees of freedom and limi tations in clinical practice显示文摘Guckenberger M Meyer J Wilbert J 2007Strahlenther Onkol2007,183,6:1
20Adaptive radiotherapyfor locally advanced non-small-cell lung Cancer does not underdosethe microscopic disease and has the potential to increase tumorcontrol显示文摘Guckenberger M Richter A Wilbert J 2011Int J Radiat Oncol Biol Phys2011,81,4:1
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