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| 1 | Safety and success of precut biliary sphincterotomy: Is it linked to experience or expertise?显示文摘瞄准:决定成功的率和按规格裁切的复杂并发症胆汁的括约肌切开术(PBS ) 基于优先的经验并且到比较在 PBS 和标准内视镜的括约肌切开术(ES ) 之间的复杂并发症率。方法:回顾的评估有希望地在一个学术第三级的工作分派中心收集了非使随机化的数据。包括的学习没有 formal 在 PBS 训练的由单个 endoscopist 经历了 PBS 和 ES 的在一个八年的时期的所有病人。学习的主要结果措施是有到 ES 的复杂并发症的比较的 PBS 的成功和复杂并发症。结果:一个总数 2939 内视镜后退 cholangiopancreatographies (ERCP ) 在学习时期期间被执行,包括 818 (28%) ES 并且 150 (5%) PBS 过程。经由 PBS 的选择胆汁的管子在在 75% 病人的第一次尝试是成功的。管子被完成在一另外在一次随后的尝试(总数 87%) 的 13% 病人。从 PBS 的复杂并发症率比 ES 高是 45% ,但是没显著地不同[7%(10/50 ) 对 5%(38/818 ) , P = 0.29 ] 。任何一个从 PBS 的复杂并发症都不是严重的。向增加成功的一个重要趋势关于 endoscopist 存在 ?ˉs 在按规格裁切的第一次尝试(P = 0.0393,为趋势的 Cochran-Armitage 准确测试, Z =-1.7588) 。结论:尽管有在这种技术的特定的训练的缺乏, PBS 从另外的富有经验的中心与高成功率和类似于的复杂并发症率或不到报告被执行。这些结果建议内视镜的经验和也许天生的内视镜的技巧可以在这个过程的结果起一个重要作用。 | Lindsay S Robison Shyam Varadarajulu C Mel Wilcox | 2007 | World Journal of Gastroenterology2007，13，15： | 10 |
| 2 | Sphincter of Oddi dysfunction Type Ⅲ: New studies suggest new approaches are needed显示文摘Sphincter of Oddi dysfunction(SOD) has been classified into three types based upon the presence or absence of objective findings including liver test abnormalities and bile duct dilatation. Type Ⅲ is the most controversial and is classified as biliary type pain in the absence ofany these objective findings. Many prior studies have shown that the clinical response to endoscopic therapy is higher based upon the presence of these objective criteria. However, there has been variable correlation of the manometry findings to outcome after endoscopic therapy. Nevertheless, manometry and sphincterotomy has been recommended for Type Ⅲ patients given the overall response rate of 33%, although the reported response rates are highly variable. However, all of the prior data was non-blinded and non-randomized with variable follow-up. The evaluating predictors in SOD study- a prospective randomized blinded sham controlled one year outcome study showed no correlation between manometric findings and outcome after sphincterotomy. Furthermore, patients receiving sham therapy had a statistically significantly better outcome than those undergoing biliary or dual sphincterotomy. This study calls into question the whole concept of SOD Type Ⅲ and, based upon prior physiologic studies, one can suggest that SOD Type Ⅲ likely represents a right upper quadrant functional abdominal pain syndrome and should be treated as such. | C Mel Wilcox | 2015 | World Journal of Gastroenterology2015，21，19： | 6 |
| 3 | Endoscopic closure of a gastrocolic fistula using the over-the-scope-clip-system显示文摘Gastrointestinal (GI) defects such as fistulas and leaks can be potentially closed endoscopically using hemo-clips and loops. However, hemoclips may not allow for closure of large defects and they do not exert enough tensile force to keep fibrotic defects larger than 5 mm approximated. Herein we present a case of successful endoscopic closure of a gastrocolic fistula in a severely malnourished patient with complex post-surgical upper GI anatomy. We strongly believe that this device is a major breakthrough for the management of various types of discontinuity defects or fistulas. In addition, we show the usefulness of placing a direct jejunostomy using the double balloon enteroscopy (DBE) technique during the same procedure. The concept of providing direct jejunal feedings while allowing for upper gas-trointestinal bowel rest to promote the healing of the minimally invasive endoscopic operation is novel. Thus, our case is unique and exemplifies the utility of mini-mally invasive endoscopic endoluminal surgery. | Klaus Mnkemüller Shajan Peter Basem Alkurdi Jayapal Ramesh Daniel Popa C Mel Wilcox | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，8： | 5 |
| 4 | Use of anesthesia on the rise in gastrointestinal endoscopy显示文摘Conscious sedation has been the standard of care for many years for gastrointestinal endoscopic procedures. As procedures have become more complex and lengthy, additional medications became essential for adequate sedation. Often time's deep sedation is required for procedures such as endoscopic retrograde cholangiography which necessitates higher doses of narcotics and benzodiazepines or even use of other medications such as ketamine. Given its pharmacologic properties, pro-pofol was rapidly adopted worldwide to gastrointestinal endoscopy for complex procedures and more recently to routine upper and lower endoscopy. Many studies have shown superiority for both the physician and patient compared to standard sedation. Nevertheless, its use remains highly controversial. A number of studies worldwide show that propofol can be given safely by endoscopists or nurses when well trained. Despite this wealth of data, at many centers its use has been pro-hibited unless administered by anesthesiology. In this commentary, we review the use of anesthesia support for endoscopy in the United States based on recent data and its implications for gastroenterologists world-wide. | Basil Al-Awabdy C Mel Wilcox | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，1： | 5 |
| 5 | Dietary protein effects on nitrogen excretion and manure characteristics of lactating cows显示文摘 | Tomlinson A P Powers W J H H Van Horn R A Nordst-edt C J Wilcox | 1996 | Trans Am Soc Agric Eng1996，39，： | 1 |
| 6 | How patch configuration affects the impact of disturbances on metapopulation persistence显示文摘 | Vuilleumier S Wilcox C | 2007 | Theoretical Population Biology2007，72，： | 1 |
| 7 | Simulation of transition with a Two- Equation turbulence model显示文摘 | Wilcox D C | 1994 | AIAA Journal1994，32，2： | 1 |
| 8 | Somatostatin analogues in the treatment of recurrent bleeding from gastrointestinal vascular malformations:an overview and systematic review of prospective observational studies显示文摘 | Brown C Subramanian V Wilcox CM | | 0，，： | 1 |
| 9 | Somatostatin analogues in the treatment of recurrent bleeding from gastrointestinal vascular malformations:an overview and systematic review of prospective observational studies显示文摘 | Brown C Subramanian V Mel Wilcox C | 2010 | Dig Dis Sci2010，55，8： | 1 |
| 10 | Tissue engineering of cardiac valves: reseeding of acellular porcine aortic valve matrices with human mesenehymal progenitor cells显示文摘 | Knight RL Booth C Wilcox HE | 2005 | J Heart Valve Dis2005，14，6： | 1 |
| 11 | The Coon Creek water yield augmentation project:implementation of timber harvesting technology to increase streamflow显示文摘 | Troendle C A Wilcox M S Bevenger G S | 2001 | Forest Ecology and Management2001，143，： | 1 |
| 12 | Flexible interdigital PVDF transducers for the generation of Lamb waves in structures显示文摘 | MONKHOUSE R S C WILCOX P D CAWLEY P | 1997 | Ultrasonics1997，35，7： | 1 |
| 13 | Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels显示文摘 | Wilcox J N Subramanian R R Sundell C | 1997 | Arterioscler Thromb Vasc Biol1997，17，11： | 1 |
| 14 | Simulation of transition with a two-equation turbulence model显示文摘 | Wilcox D C | 1994 | AIAA Journal1994，32，2： | 1 |
| 15 | Pharmacological profiles of alpha 2 adrenergic receptor agonists identied using genetically al- tered mice and isobolographic analysis 显示文摘 | Fairbanks C A Stone L S Wilcox G L | 2009 | Pharmacol Ther2009，123，4： | 1 |
| 16 | Efficient computation of RCS from scatterers of uncertain shapes 显示文摘 | Chauviere C Hesthaven J S and Wilcox L C | 2007 | IEEE Transactions on Antennas and Propagation2007，55，5： | 1 |
| 17 | Mo- netary Policy and Credit Conditions:Evidence from the Composition of External Finance显示文摘 | KASHYAP A STEIN K WILCOX J C | 1993 | American Economic Review1993，，83： | 1 |
| 18 | Does Consumer Sentiment Forecast Household Spending?If So,Why显示文摘 | Carroll C Fuhrer J Wilcox D | | 0，，05： | 1 |
| 19 | Mercury adsorption and oxidation incoal combustion and gasification processes显示文摘 | WILCOX J E RUPP S C YING D H LIM A S NEGREIRA A KIRCHOFER A FENG F LEE K | 2012 | Int J Coal Geol2012，9091，： | 1 |
| 20 | Development of a computer model for an ultrasonic polymer film transducer system显示文摘 | WILCOX P D MONKHOUSE R S C CAWLEY P | 1998 | NDT&E International1998，31，1： | 1 |
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