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346篇 您的检索式:作者名="Willette R"
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1Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien 2012Cell Research2012,22,1:7
2粗饲料种类、可代谢蛋白质浓度、碳水化合物来源对奶牛养分消化率及生产性能的影响显示文摘本试验采用中心组合试验设计对粗饲料来源、可代谢蛋白质(MP)浓度、碳水化合物种类及其互作效应对奶牛养分消化率和生产性能的影响进行了评价。所有日粮(干物质基础)均有50%由苜蓿青贮、玉米青贮构成的粗饲料、10.7%的瘤胃降解蛋白质(RDP)、4.1%~7.1%的瘤胃未降解蛋白质(RUP)、8.8%~12%的MP和22%~30%的淀粉组成。本试验共有15种日粮,试验牛分为6个区组,每个区组6头荷斯坦奶牛,分别进行3个为期21 d的试验。每期按特定顺序饲喂3种日粮后测定试验牛的产奶量、乳成分、采食量及主要营养物质消化率,还考虑了几个主要影响因素间的互作效应。结果表明:日粮淀粉浓度对奶牛养分消化率和生产性能影响较小;用苜蓿青贮代替玉米青贮可降低奶牛的氮消化率、提高中性洗涤纤维(NDF)消化率,还能增加奶牛对日粮干物质(DM)和日粮消化能(DE)摄入量,从而提高能量校正乳(ECM)、乳脂及乳蛋白产量;增加日粮MP浓度可提高奶牛对氮的消化率、ECM和乳蛋白产量,但乳蛋白含量的变化远小于NRC所推荐模型的预测值;DE浓度随淀粉浓度升高呈线性升高,但同时受粗饲料种类和MP浓度互作的影响,即日粮MP浓度较低时,DE浓度会随苜蓿青贮比例升高而降低,而日粮MP浓度较高时,DE浓度会随苜蓿青贮比例升高而升高。郑宇慧 李胜利 Weiss WP St-Pierre N R Willett L B 2018中国畜牧杂志2018,54,11:4
3Differential toxicity and environmental fates of hexachlorocyclohexane isomers显示文摘Willett K L Ulrich E M Hites R A 1998Environ Sci Technol1998,32,15:2
4Light-scattering molecular weight and intrinsic viscosities of processed waxy maize starches in 90% dimethyl sulfoxide and H2O显示文摘Millard M M Dintzis F R Willett J L 1997Cereal Chemistry1997,74,:1
5The PMHT:problems and some solutions显示文摘WILLETT P RUAN Y STREIT R 2002IEEE Transaction on Aerospace and Electronic Systems2002,38,3:1
6Differential toxicity and environmental fates of HCH isomers显示文摘Willett K L Ulrich E M Hites R A 1998Environ Sci Technol1998,32,15:1
7Dissolved organic nitrogen uptake by plants-an important N uptake pathway?显示文摘JONES D L HEALEY J R WILLETT V B 2005Soil Biol Biochem2005,37,3:1
8Clinical perspectives of calcitoni gene related peptide pharmacology显示文摘 Willette R Aiyar N 1995Can J Physiol Pharmacol1995,73,7:1
9Differential toxicity and environmental fates of hexaehlorcyelohexane isomers显示文摘Willett K L Ulrich E M Hires R A 1998Environmental Sciellce and Technology1998,32,:1
10Purification and properties of a novel insulin-like growth factor-If binding protein from transformed human fibroblasts 显示文摘Martin J L Willetts K E Baxter R C 1990The Journal of biological chemistry1990,265,7:1
11Understanding anaerobic decolourisation of textile dye wastewater: mechanism and kinetics显示文摘Willetts J R M Ashboh N J 2000Water Sci Technol2000,42,12:1
12Differential toxicity and environmental fats of hexachlorocyclohexane isomers 显示文摘Willett K L Ulrich E M Hites R A 1998Environmental Science Technology1998,32,:1
13Differential toxicity and environmental fats of hexachlorocyclohexanes isomers 显示文摘Willett K L Ulrich E M Hires R A 1998Environ Sci Technol1998,32,:1
14The Influences of Salaries and “Opportunity Costs”on Teachers’Career Choices:Evidence from North Carolina显示文摘Murnane R Singer J Willett J 0,,3:1
15The use of interlocked 'customized' blade plates in the treatment of metaphyseal fractures in patients with poor bone stock显示文摘Palmer SH Handley R Willett K 0,,:1
16Near-optimal multiuser detection in synchronous CDMA using prob-abilistic data association显示文摘Luo J Pattipati K R Willett P K 0,,09:1
17Single-shot compressive spectral imaging with a dual disperser architecture显示文摘M Gehm R John D Brady R Willett T Schulz 2007Opt Express2007,15,14:1
18Differential toxicity and environmental fates of hexachlorcyclohexane isomers 显示文摘Willett K L Ulrich E M Hites R A 1998Environmental Science & Technology1998,32,:1
19Differential toxicity and environmental fates of hexachlorocyclohexane isomers显示文摘WILLETT K L ULRICH E M HITES R A 1998Environmental Science & Technology1998,32,15:1
20Single disperser design for coded aperture snapshot spectral imaging显示文摘A Wagadarikar R John R Willett D Brady 2008Appl Opt2008,47,10:1
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