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| 1 | 代谢酶NAT2多态性与大肠息肉及腺瘤的复发显示文摘目的 研究代谢酶基因NAT2多态性与大肠息肉及腺瘤复发的关系 ,探讨其与大肠癌遗传易感性。方法 在 1980年 ,建立了 40 76例大肠癌高危人群队列 ,这 40 76例均有大肠腺瘤或息肉史。从高危人群中随机抽取 5 2例息肉、腺瘤复发 2次以上者为复发组 ,另抽取 5 2例无复发者为对照 ,从抗凝外周血白细胞中提取DNA ,采用聚合酶链反应 限制性内切酶片段长度多态性 (PCR RFLP)方法分析 ,比较NAT2的多态性分布差异。结果 NAT2野生型Wt/Wt频率在无复发组 (17/ 5 2 ,32 7% )明显高于复发组 (8/ 5 2 ,15 .4% ) ,杂合型在复发组频率为 40 / 5 2 (76 .9% ) ,与无复发组频率30 / 5 2 (5 7.7% )比较 ,差异均有显著意义 (P <0 .0 5 )。以Wt/Wt基因型的危险度 (OR)为 1,则Wt/M 基因型的OR为 2 .96 ,95 %CI为 1.0 91~ 8.0 0 9,M /M 基因型的OR为 2 .12 5 ,95 %CI为 0 .6 6 6~6 781。在复发与无复发组中 ,未发现NAT2快速与慢速酶的差异。结论 NAT2野生型 (Wt/Wt)可能是大肠腺瘤复发的保护因素 。 | 郑树 刘希永 曹江 Rebecca A.Nelson 董琦 方永明 William Bennett 蔡善荣 张苏展 | 2001 | 中华医学杂志2001，81，15： | 7 |
| 2 | 水力压裂监测新方法显示文摘深入了解水力压裂裂缝的几何形态和延伸情况有助于改善低渗油气藏压裂增产作业效果,改善油气井产能并提高油气采收率。应用地震方法对水力压裂裂缝进行监测和描述已经有多年了,而新的地震硬件和处理技术的出现使得这类监测更加有效、可靠。 | Les Bennett Joeol Le Calvez David R. ( Rich ) Sarver Kevin Tanner W.S.(Scott)Birk George Waters Julian Drew Gw e nola Michaud Paolo Primiero Leo Eisner Rob Jones David Leslie Michael John Williams Jim Govenlock Richard C. ( Rick ) Klein Kazuhiko Tezuka | 2007 | 国外测井技术2007，22，4： | 7 |
| 3 | Histological abnormalities of the small bowel mucosa in cirrhosis and portal hypertension显示文摘AIM: To study the small bowel (SB) mucosa on biopsy in cirrhotic patients with portal hypertension and in non-cirrhotic controls and grade fi ndings according to the Marsh criteria. METHODS: We prospectively enrolled 51 consecutive patients undergoing an upper endoscopy for their routine medical care. Twenty f ive patients with cirrhosis and portal hypertension were compared to 26 controls. We obtained coeliac serology and multiple upper small bowel biopsies on all 51 patients. A GI pathologist interpreted biopsies and graded fi ndings according to the Marsh criteria. We assessed equivalence in Marsh grade between cirrhotic and non-cirrhotic controls using the Mann-Whitney test for equivalence. RESULTS: Gender, ethnicity and age were similar between both groups. Marsh grades were equivalent between the groups. Grade of 0 was present in 96% and grade of 1 was present in 4% of both groups and there was no villus atrophy or decrease in villus/crypt ratio in patients with portal hypertension. CONCLUSION: This study provides evidence for the lack of villus atrophy in patients with cirrhosis and portal hypertension, and supports the continuous reliance on the Marsh criteria when the diagnosis of coeliac disease is to be made in the presence of cirrhosis. | Jamilé Wakim-Fleming Nizar N Zein Ana Bennett Rocio Lopez Janice Santisi William D Carey | 2008 | World Journal of Gastroenterology2008，14，41： | 4 |
| 4 | Perihepatic Lymph Node Micrometastases Impact Outcome after Partial Hepatectomy for Colorectal Metastases显示文摘 | Joseph J. Bennett MD Carl R. Schmidt MD David S. Klimstra MD Stephen R. Grobmyer MD Nicole M. Ishill MS Michael D'Angelica MD Ronald P. DeMatteo MD Yuman Fong MD Leslie H. Blumgart MD William R. Jarnagin MD | 2008 | Annals of Surgical Oncology2008，，4： | 2 |
| 5 | A New Definition of Genetic Counseling: National Society of Genetic Counselors’ Task Force Report显示文摘 | Robert Resta Barbara Bowles Biesecker Robin L. Bennett Sandra Blum Susan Estabrooks Hahn Michelle N. Strecker Janet L. Williams | 2006 | Journal of Genetic Counseling2006，，： | 1 |
| 6 | Statins and risk of treated incident diabetes in a primary care population 显示文摘 | Zaharan NL Williams D Bennett K | 2013 | Br J Clin Pharmacol2013，75，4： | 1 |
| 7 | Suppression of Vascular Endothelial Growth Factor-Mediated Endothelial Cell Protection by Survivin Targeting显示文摘 | Mehdi Mesri Manuel Morales-Ruiz Elizabeth J. Ackermann C. Frank Bennett Jordan S. Pober William C. Sessa Dario C. Altieri | 2001 | The American Journal of Pathology2001，，5： | 1 |
| 8 | Diagenesis of fossil ostracods: Implications for stable isotope based palaeoenvironmental reconstruction显示文摘 | Carys E. Bennett Mark Williams Melanie J. Leng David J. Siveter Sarah J. Davies Hilary J. Sloane Ian P. Wilkinson | 2011 | Palaeogeography, Palaeoclimatology, Palaeoecology2011，，1： | 1 |
| 9 | Analysisof bovine immunoglobulin G by capillary gel electrophore-sis显示文摘 | Bennett L E Charman W N Williams D B | 1994 | Journal of pharmaceutical and biomedical analysis1994，12，9： | 1 |
| 10 | Extension of the Wittrick-Williams algorithm to mixed variable systems显示文摘 | Zhong W X Williams F W Bennett P N | 1997 | J Vib & Acous Trans ASME1997，119，13： | 1 |
| 11 | AJC Editor’s Consensus: Selective and Nonselective Nonsteroidal Anti-Inflammatory Drugs and Cardiovascular Risk显示文摘 | Vincent E. Friedewald Joel S. Bennett J. Paul Christo James L. Pool James M. Scheiman Lee S. Simon Vibeke Strand William B. White Gary W. Williams William C. Roberts | 2010 | The American Journal of Cardiology2010，，： | 1 |
| 12 | Presence and hazards of nutrients and emerging organic micropollutants from sewage lagoon discharges into Dead Horse Creek, Manitoba, Canada显示文摘 | Jules C. Carlson Julie C. Anderson Jennifer E. Low Pascal Cardinal Scott D. MacKenzie Sarah A. Beattie Jonathan K. Challis Renae J. Bennett Stephanie S. Meronek Rebecca P.A. Wilks William M. Buhay Charles S. Wong Mark L. Hanson | 2012 | Science of the Total Environment2012，，： | 1 |
| 13 | Visual search and biological motion perception in tennis显示文摘 | WARD P WILLIAMS M A BENNETT SJ | 2002 | Research Quarterly for Exercise and Sport2002，，73： | 1 |
| 14 | Statins and risk of treated incident diabetes in a primary care population显示文摘 | Zaharan NL Williams D Bennett K | | 0，，： | 1 |
| 15 | Associations between orga-nizational and incident factors and emotional distress in emergency ambulance personnel显示文摘 | Bennett P Williams Y Page N | 2001 | Br J Clin Psychol2001，178，1： | 1 |
| 16 | Propagationof stationary random waves along sub-structural chains显示文摘 | Lin J H Fan Y Bennett P N Williams F W | 1995 | Journal of Sound and Vibration1995，180，5： | 1 |
| 17 | Detection of hepatitis C virus RNA in dried blood spots显示文摘 | Susan Bennett Rory N. Gunson Georgina E. McAllister Sharon J. Hutchinson David J. Goldberg Sheila O. Cameron William F. Carman | 2012 | Journal of Clinical Virology2012，，2： | 1 |
| 18 | Structure-function analysis of the presumptive Arabidopsis auxin permease AUXI显示文摘 | SWARUP R KARGUL J MARCHANT A ZADIK D RAHMAN A MILLS R YEMM A MAY S WILLIAMS L MILLNER P ET A L TSURUMI S MOORE I NAPIER R KERR I D BENNETT M J | 2004 | Plant Cell2004，16，11： | 1 |
| 19 | Demonstration of sites of latency of infectious laryngotracheitis virus using the polymerase chain reaction显示文摘 | WILLIAMS R A BENNETt M BRADBURY J M | 1992 | J Gen Virol1992，73，9： | 1 |
| 20 | 查看详情显示文摘 | Bennett C H Divincenzo D P Smolin J A Smolin William K Wootters | | 0，，： | 1 |
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