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| 1 | 新一代渴望导管: 在肺的栓塞的处理的可行性显示文摘 AIM: To report our preliminary experience with a new generation aspiration catheter in the treatment of symptomatic pulmonary embolism(PE). METHODS: A retrospective database search for pulmonary artery embolectomy since introduction of the Pronto.035' and XL extraction catheter(Vascular Solutions, Minneapolis, MN) at our institution in 10/2009 was performed. Ten consecutive patients were identified in which the Pronto.035' or XL catheter was used between 01/2010 and 03/2013. All patients were referred for catheter based embolectomy due to contraindications to systemic lysis, or for being in such a critical clinical condition that immediate percutaneous treatment deemed warranted. The computed tomography(CT) right to left heart ratio as predictor for the severity of the PE was retrospectively evaluated on standard axial views. The difference between pre- and post-procedure pulmonary pressure measures was taken to assess the procedural effect.RESULTS: Extensive PE was confirmed angiographically in all patients. Measured right- to left ventricle(RV/LV) ratios were elevated beyond one in seven of the eight available CTs. Acute procedural success defined as clinical removal of visible thrombus and improvement in mean pulmonary artery pressure was seen in all recorded patients(n = 8), the mean pulmonary pressures declined from a median(range) of 35.5(19-46) to 23(10-37, P = 0.008) mmHg. Neither death nor other complications occurred intra- or immediately periprocedural, yet short term mortality within 30 d was found in 6 out of 9 patients, one patient was lost in follow up. The cause of death within 30 d in the 6 patients was identified as: Circulatory failure in direct connection with the PE(n = 2), stroke, sepsis, or succumbing to malignancy in a hospice setting(n = 2). CONCLUSION: Success in thrombus removal with improved pulmonary hypertension and systemic hypotension suggests this aspiration technique to be effective. Aspiration catheters should be part of further trials. | Wolf E Heberlein Mollie E Meek Omar Saleh James C Meek Shelly Y Lensing William C Culp | 2013 | World Journal of Radiology2013，5，11： | 2 |
| 2 | Therapeutic applications of lipid-coated microbubbles 显示文摘 | Unger Evan C Thomas Porter William Culp | 2004 | Advanced Drug Delivery Reviews2004，56，9： | 1 |
| 3 | Mightmen diagnosed with metastatic prostate cancer benefit from de nitive treatment of the primary tumor? A SEER-based study 显示文摘 | Culp SH Schellhammer PF Williams MB | 2014 | Eur Urol2014，65，6： | 1 |
| 4 | Therapeutic applications of lipid-coated microbubbles显示文摘 | Evan C. Unger Thomas Porter William Culp Rachel Labell Terry Matsunaga Reena Zutshi | 2004 | Advanced Drug Delivery Reviews2004，，9： | 1 |
| 5 | Might men diagnosed with metastatic prostate cancer benefit from definitive treatment of the primary tumor? A SEER-based study 显示文摘 | Culp SH Sehellhammer PF Williams MB | 2014 | Eur Urol2014，65，： | 1 |
| 6 | Might men diagnosedwith metastatic prostate cancer benefit from definitive treatment ofthe primary tumor? A SEER-based study显示文摘 | Culp SH Schellhammer PF Williams MB | 2014 | Eur Urol2014，65，： | 1 |
| 7 | 手术中用三维经食道超声心动图测量心输出量的准确性和可行性显示文摘背景本研究中,我们试图用三维经食道超声心动图(3DTEE)确定心输出量,并评价其在手术中应用的可行性。方法同时用3DTEE和热稀释.法测定20例行心脏手术的患者在临床上稳定的体外循环前期时的心输出量。结果用这2种方法测定心输出量之间的相关系数是0.86。3DTEE的平均偏差是0.27L/min,范围是一1.64—2.17L/min(一致性为±35%)。平均三维数据采集时间为43秒,数据后处理时间为7分钟。结论可以用3DTEE来测量心输出量,并且这种方法在围手术期是可行的。虽然这种方法同热稀释法相比差异有显著性,且一致性较差,但是与热稀释法有很好的相关性。 | William C. Culp Timothy R.Ball Christopher J. Burnett 易莉莎(译) 姚尚龙(校) | 2009 | 麻醉与镇痛2009，，1： | 1 |
| 8 | Might men diagnosed with metastatic prostate cancer benefit from de- finitive treatment of the primary tumor? A SEER-based study 显示文摘 | CULP SH SCHELLHAMMER PF WILLIAMS MB | 2014 | Eur Urol2014，65，6： | 1 |
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