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120篇 您的检索式:作者名="Williams AH"
    题名 作者 年代 出处 被引量
1Effect of Graphene Nanoribbons (TexasPEG) on locomotor function recovery in a rat model of lumbar spinal cord transection显示文摘A sharply transected spinal cord has been shown to be fused under the accelerating influence of membrane fusogens such as polyethylene glycol(PEG)(GEMINI protocol). Previous work provided evidence that this is in fact possible. Other fusogens might improve current results. In this study, we aimed to assess the effects of PEGylated graphene nanoribons(PEG-GNR, and called 'Texas PEG' when prepared as 1 wt% dispersion in PEG600) versus placebo(saline) on locomotor function recovery and cellular level in a rat model of spinal cord transection at lumbar segment 1(L_1) level. In vivo and in vitro experiments(n = 10 per experiment) were designed. In the in vivo experiment, all rats were submitted to full spinal cord transection at L_1 level. Five weeks later, behavioral assessment was performed using the Basso Beattie Bresnahan(BBB) locomotor rating scale. Immunohistochemical staining with neuron marker neurofilament 200(NF200) antibody and astrocytic scar marker glial fibrillary acidic protein(GFAP) was also performed in the injured spinal cord. In the in vitro experiment, the effects of Texas PEG application for 72 hours on the neurite outgrowth of SH-SY5 Y cells were observed under the inverted microscope. Results of both in vivo and in vitro experiments suggest that Texas PEG reduces the formation of glial scars, promotes the regeneration of neurites, and thereby contributes to the recovery of locomotor function of a rat model of spinal cord transfection.C-Yoon Kim William K. A. Sikkema Jin Kim Jeong Ah Kim James Walter Raymond Dieter Hyung-Min Chung Andrea Mana James M. Tour Sergio Canavero 2018Neural Regeneration Research2018,13,8:2
2An intragenie MEF2- dependent enhancer directs muscle-specific expression of microRNAs 1 and 133显示文摘Liu N Williams AH Kim Y 2007Proc Natl Acad Sci USA2007,104,20:1
3Prevention of Venous Thromboembolism: The seventh ACCP conference on antithrombotic and thrombolytic Therapy 显示文摘William HG Graham FP John AH 2004Chest2004,126,3:1
4MicroRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice显示文摘Liu N Williams AH Maxeiner JM 2012Clin Invest2012,122,6:1
5A GABAergic system in airway epithelium is essential for mucus overproduction in asthma显示文摘YunYan X Shuhe W Mingyao L Jeremy AH Jingxin L William J 0,,:1
6Retrospective analysis of a- dult patlents with cutaneous leukocytoclastic vasculitis显示文摘Tai YJ Chong AH Williams RA 2006Australas J Dermatol2006,47,2:1
7Early experience with retrievable Inferior vena cava filters in high-risk trauma patients显示文摘William SH Brian AH Gail AW 2004J Am Coll Surg2004,199,6:1
8Facial Sweet's syndrome mimicking rosacea fulminans 显示文摘Anavekar NS Williams R Chong AH 2007Australas J Dermatol2007,48,1:1
9Incidence and impact of axial malformations in larval bullfrogs(Rana catesbeiana)developing in sites polluted by a coal-burning power plant显示文摘William AH Justin C John KR 2000Environmental Toxicology and Chemistry2000,19,4:1
10MicroRNA-133a regulates car-diomyocyte proliferation and suppresses smooth muscle gene expression in the heart显示文摘Liu N Bezprozvannaya S Williams AH 2008Genes Dev2008,22,23:1
11Distinct amygdala-autonomic arousal profiles in response to fear signals in healthy males and females显示文摘Williams LM Barton MJ Kemp AH 2005Neuroimage2005,28,3:1
12Inhibition of growth of cervicalcancer cells usinga dominant negative estrogen receptor gene 显示文摘William W Salama AS Ayman AH 2007Gynecol Oncol2007,104,2:1
13An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133 显示文摘Liu N Williams AH Kim Y 2007Proc Natl Acad Sci USA2007,104,20:1
14Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase显示文摘Williams AH Raetz CR 0,,:1
15Mood and neuropsychological function in depression: the role of corticosteroids and serotonin 显示文摘Williams RHM Ferrier IN Young AH 1998Psychological Medicinel1998,28,:1
16mieroRNA-133a regulates eardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart显示文摘Liu N Bezprozvannaya S Williams AH 2008Genes Dev2008,22,23:1
17Mood and neuropsychological function in depression: the role of corticosteroids and serotonin显示文摘Mc Allister - Williams RH Ferrier IN Young AH 1998Psychol Med1998,28,3:1
18Structural determinants of blockade of N-type calcium channels by apeptide neurotoxin显示文摘Patric TE Ji-fang Zhang William AH 1994Nature1994,17,:1
19microRNA-133aregulates cardiomyocyte proliferation and suppresses smooth musclegene egression in the heart 显示文摘Liu N Bezprozvannaya S Williams AH 2008Genes Dev2008,22,23:1
20A review of the safety profile of teicoplanin显示文摘Davery PG Williams AH 1991J Antimicrob Chemother1991,27,:1
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