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| 1 | Accuracy of Risk Scores for Patients With Chronic Hepatitis B Receiving Entecavir Treatment显示文摘 | Grace Lai–Hung Wong Henry Lik–Yuen Chan Hoi–Yun Chan Pete Chi–Hang Tse Yee–Kit Tse Christy Wing–Hin Mak Stanley King–Yeung Lee Zoe Man–Yi Ip Andrew Ting–Ho Lam Henry Wing–Hang Iu Joyce May–Sum Leung Vincent Wai–Sun Wong | 2013 | Gastroenterology2013，，5： | 2 |
| 2 | Entecavir treatment reduces hepatic events and deaths in chronic hepatitis B patients With liver cirrhosis显示文摘 | Grace Lai‐Hung Wong Henry Lik‐Yuen Chan Christy Wing‐Hin Mak Stanley King‐Yeung Lee Zoe Man‐Yi Ip Andrew Ting‐Ho Lam Henry Wing‐Hang Iu Joyce May‐Sum Leung Jennifer Wing‐Yan Lai Angeline Oi‐Shan Lo Hoi‐Yun Chan Vincent Wai‐Sun Wong | 2013 | Hepatology2013，，5： | 1 |
| 3 | Ex vivo comparative study using the Endolifter ? as a traction device for enhancing submucosal visualization during endoscopic submucosal dissection显示文摘 | Anthony Yuen Bun Teoh Philip Wai Yan Chiu So Fei Hon Tony Wing Chung Mak Enders Kwok Wai Ng James Yun Wong Lau | 2013 | Surgical Endoscopy2013，，4： | 1 |
| 4 | Surrogate End Points and Long-Term Outcome in Patients With Chronic Hepatitis B显示文摘 | Vincent Wai–Sun Wong Grace Lai–Hung Wong Angel Mei–Ling Chim Paul Cheung–Lung Choi Anthony Wing–Hung Chan Steven Woon–Choy Tsang Alex Yui Hui Hoi–Yun Chan Joseph Jao–Yiu Sung Henry Lik–Yuen Chan | 2009 | Clinical Gastroenterology and Hepatology2009，，10： | 1 |
| 5 | Application of biomarkers in sentinel lymph node biopsy for the management of breast cancer显示文摘Objective Sentinel lymph node in breast cancer is a predictor of the tumor's metastatic potential.Cytokines emerging from antitumor immune response might also target sentinel lymph node (SLN).In this study,we evaluated the cytokine profile including interleukin-8 (IL-8),interleukin-12 (IL-12),interferon-gamma (IFN-γ),and tumor necrosis factor alpha (TNF-α) for the T-cell response.Methods From January 2008 to August 2010,35 patients with breast mass underwent SLN biopsy in UNIMED Medical Institute.The specimens were formalin-fixed and paraffin-embedded for hematoxylin and eosin staining and immunohistochemistry with following markers:IL-8,IL-12,IFN-γ and TNF-α.The staining intensity was scored according to four grades:negative (-),weak expression (+),moderately positive expression (+ +),strong positive expression (+ + +).The correlation between the expression of cytokines and pathological characteristics were also analyzed using the Spearman Rank Correlation test.Results Out of 35 patients,SLN metastases were observed in 20 patients and among them,75% (15 /20) were strongly stained (+ + +) with IL-8 and moderately stained (+ +) with IL-12,but only 25% (5 /20) were strongly stained (+ + +) with IFN-γ and TNF-α.The expression of IL-8 was significantly associated with all tumor grades (r=0.639,P=0.00),estrogen receptor (r=0.778,P=0.01),progesterone receptor (r=0.759 P=0.00) and HER-2 /neu receptor (r=0.863 P=0.00).Conclusion The strong association between IL-8 expression and SLN metastases might highlight the prognostic significance of IL-8 in SLN. | Qing Liu Wings Tjing Yung Loo Adrian Yun San Yip Louis Wing Cheong Chow Elizabeth Lam Yan Ng Mary Ngan Bing Cheung | 2012 | 中华乳腺病杂志(电子版)2012，6，6： | 1 |
| 6 | Overview of breast cancer prevention:what's the next?显示文摘Breast cancer is the leading cause of death among women at the ages of 20-59 years[1].The incidence of breast cancer in Asia is also shown to be increasing recently,especially in the more affluent cities,and the peak incidence of breast cancer is at the age of 45-50 years[2].Breast cancer prevention has started from secondary prevention strategy of early detection of the disease with different modalities in Asia[3-5]despite the absence of unified nationwide screening program.There are a lot | LouisWingCheongChow WingsTjingYungLoo AdrianYunSanYip Louis Wing Cheong Chow Wings Tjing Yung Loo Adrian Yun San Yip | 2013 | 中华乳腺病杂志(电子版)2013，7，6： | 0 |
| 7 | Avascular necrosis of the first metatarsal head in a young female adult:A case report and review of literature显示文摘BACKGROUND This case study describes an atypical presentation of avascular necrosis(AVN)of the first metatarsal head,which is largely unfounded in the literature.CASE SUMMARY A healthy 24-year-old female initially presented with pain at the first metatarsophalangeal joint(MTPJ)and was diagnosed with AVN by physical examination and magnetic resonance imaging.The patient demonstrated atypically poor progress in recovery,despite being in otherwise good health and being of young age,with no history of corticosteroid or alcohol use.The patient also did not have any history or clinical features of autoimmune disease or vasculitis,such as systemic lupus erythematosus.The patient was managed with conservative treatment for 18 mo,which allowed for gradual return of full range of motion of the first MTPJ and subsiding pain,permitting the patient to return to highintensity sports training and full weight-bearing.Throughout her recovery,many differential diagnoses were ruled out through specific investigations leading to further reinforcement of the diagnosis of AVN of the 1st metatarsal head.CONCLUSION Atypical AVN may occur with no predisposing risk factors.Treatment is mainly conservative,with unclear guidelines in literature on management. | Ronald Wing Hei Siu Jeremy Ho Pak Liu Gene Chi Wai Man Michael Tim Yun Ong Patrick Shu Hang Yung | 2021 | World Journal of Clinical Cases2021，9，25： | 0 |
| 8 | 虹桥花瓣楼显示文摘MVRDV总体规划中的第一座建筑,花瓣形的标志性建筑,提供1.5万m^2甲级写字楼,结合租赁灵活强大的身份。另外4.5万m^2的地块在上海的虹桥机场边缘将包括共9栋MVRDV设计的办公楼及凯达环球设计的地下街。由MVRD为协信地产集团设计的花瓣楼获得三星级绿色大厦标签,拥有在中国最好的节能等级。 | Jacob van Rijs Wenchian Shi Aser Giménez Ortega Daehee Suk John Tsang Antonio Luca Coco Qing Chen Jose Ignacio Velasco Martin Wing Yun Zeying Song Karl Nyqvist Ke Zhang Wei Zhu Michael Zhang Jaap Baselmans Jing Zhang Sharon Sin Johan Bergstrom 申强 | 2019 | 建筑实践2019，2，6： | 0 |
| 9 | Ligand-Metal Interaction in Transition-Metal Complexes with Tripodal Polyaza Ligands显示文摘Five complexes ([Cu(tpc)] 2+ 1, [Cu(tpa)] 2+ 2, [Co(tpa)] 2+ 3, [Fe(tpa)] 2+ 4 and [Mn(tpa)] 2+ 5) (tpc = N, N’, N' tris[(2 pyridyl)methyl] 1,4,7 triaza cyclononane(L1) and tpa = tris[2 ((2 pyridyl)methyl imino)ethyl]amine(L2)) were synthesized and characterized. The crystal structures of 1, 3 and 4 were determined by X ray crystallography. Electrochemical investigations over two cupric complexes reveal that 2 has a less negative redox potential than that of 1. Electronic spectra of 2, 3, 4 and 5 show that the distinction in metal ion results in a shift of the ligand based π*←π transition. | YIN Ye gao Department of Chemistry, Jingzhou Teachers College, Jingzhou City, Hubei 434100 HUANG Zu yun College of Chemistry and Environmental Science , Wuhan University, Wuhan 430072 CHEUNG Kung kai, WONG Wing tak Department of Chemistry | 1999 | Wuhan University Journal of Natural Sciences1999，4，4： | 0 |
| 10 | Effect of Tai Chi Chuan on serotonin and cortisol for monitoring stress and quality of life in post-treatment breast cancer patients显示文摘Objective Immediate physical exercise has been recommended for patients in the recovery phase to improve survival and quality of life(QOL)and reduce recurrence of disease.The new NCCN Guidelines for Survivorship also highlighted the role of exercise in post-cancer health,encouraging patients to perform light physical activity following treatment.The aim of our study is to effect of Tai Chi Chuan(TCC)on serotonin and cortisol for monitoring stress and QOL in post-treatment breast cancer patients.Methods Totally85 post-treatment breast cancer patients were enrolled in this study to observe the effects of practicing TCC on recovery,as well as stress and happiness which are indicators of QOL of in patients.Peripheral blood was drawn from study subjects to analyze the levels of serotonin,cortisol and high sensitive C-reactive protein(HSCRP)at baseline,and at 3,6 and 12 months of TCC practice.Blood was drawn from healthy subjects only at baseline.A QOL questionnaire was administered to study subjects at three time points throughout the study,and once for healthy controls.The data were processed by analysis of variance of repeated measurement.Results At 3,6 and 12 months time points following regular TCC exercise,WBC,RBC,hemoglobin in blood samples showed a statistically significant difference(F=161.55,172.14,289.73;all P=0.00);the level of serotonin(biomarker for well-being),cortisol(indicator of stress)and HS-CRP(biomarker for inflammation)showed a statistical improvement(F=307.46,182.85,102.23;all P=0.00).After 3,6 and 12 months of regular TCC exercise,according to the results of QOL questionnaire,the indicators including quality of sleep,perceived hunger,fatigue,contentment,stress and social interaction presented a significant difference(F=312.98,222.64,543.90,46.05,28.10,78.92,all P<0.05),while there was no statistical difference in life dissatisfaction(F=56.61,P=0.166)Conclusions TCC physical activity for post-treatment breast cancer patients improved QOL and overall well-being,leading to improved mental,physical and psychological functioning.Regulated levels of serotonin and cortisol mediated by TCC exercises are proved to be vital for continued good health. | William Wai Nam Tsang Wings Tjing Yung Loo Louis Wing Cheong Chow Elizabeth Lam Yan Ng Adrian Yun San Yip Jianping Chen | 2014 | 中华乳腺病杂志(电子版)2014，8，4： | 0 |
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