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| 1 | Short term outcomes of minimally invasive selective lateral pelvic lymph node dissection for low rectal cancer显示文摘BACKGROUND Pelvic recurrence after rectal cancer surgery is still a significant problem despite the introduction of total mesorectal excision and chemoradiation treatment(CRT),and one of the most common areas of recurrence is in the lateral pelvic lymph nodes.Hence,there is a possible role for lateral pelvic lymph node dissection(LPND)in rectal cancer.AIM To evaluate the short-term outcomes of patients who underwent minimally invasive LPND during rectal cancer surgery.Secondary outcomes were to evaluate for any predictive factors to determine lymph node metastases based on pre-operative scans.METHODS From October 2016 to November 2019,22 patients with stage II or III rectal cancer underwent minimally invasive rectal cancer surgery and LPND.These patients were all discussed at a multidisciplinary tumor board meeting and most of them received neoadjuvant chemoradiation prior to surgery.All patients had radiologically positive lateral pelvic lymph nodes on the initial staging scans,defined as lymph nodes larger than 7 mm in long axis measurement,or abnormal radiological morphology.LPND was only performed on the involved side.RESULTS Majority of the patients were male(18/22,81.8%),with a median age of 65 years(44-81).Eighteen patients completed neoadjuvant CRT pre-operatively.18 patients(81.8%)had unilateral LPND,with the others receiving bilateral surgery.The median number of lateral pelvic lymph nodes harvested was 10(3-22)per pelvic side wall.8 patients(36.4%)had positive metastases identified in the lymph nodes harvested.The median pre-CRT size of these positive lymph nodes was 10 mm.Median length of stay was 7.5 d(3-76),and only 2 patients failed initial removal of their urinary catheter.Complication rates were low,with only 1 lymphocele and 1 anastomotic leak.There was only 1 mortality(4.5%).There have been no recurrences so far.CONCLUSION Chemoradiation is inadequate in completely eradicating lateral wall metastasis and there are still technical limitations in accurately diagnosing metastases in these areas.A pre-CRT lymph node size of≥10 mm is suggestive of metastases.LPND may be performed safely with minimally invasive surgery. | Kar Yong Wong Aloysius MN Tan | 2020 | World Journal of Gastrointestinal Surgery2020，12，4： | 4 |
| 2 | Whole brain radiotherapyfor the treatment of newly diagnosed multiple brain metastases显示文摘 | Tsao MN Lloyd N Wong RKS | 2012 | Cochrane Database Syst Rev2012，4，00： | 1 |
| 3 | Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases显示文摘 | Tsao MN Lloyd N Wong RK | 2012 | Cochrane Database Syst Rev2012，4，： | 1 |
| 4 | Radiotherapeutic management of brain metastases: a systematic review and meta-analysis显示文摘 | Tsao MN Lloyd NS Wong RK | 2005 | Cancer Treat Rev2005，31，4： | 1 |
| 5 | Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases显示文摘 | Tsao MN Lloyd N Wong RK | | 0，，04： | 1 |
| 6 | Radiotherapeutic management of brain metastases: a systematic review and meta- analysis显示文摘 | Tsao MN Lloyd NS Wong RK | 2005 | Cancer Treat Rev2005，31，4： | 1 |
| 7 | Regulation of human Th9 differentiation by type I interferons and IL-21显示文摘 | Wong MT Ye JJ Alonso MN | 2010 | Im- munol Cell Biol2010，88，： | 1 |
| 8 | Radiotherapeutic management of brain metastases: A systematic review and meta-analysis显示文摘 | Tsao MN Lloyd NS Wong RK | 2005 | Cancer Treat Rev2005，31，4： | 1 |
| 9 | Regulation of human Th9 differentiation by type Ⅰ interferons and IL-21显示文摘 | Wong MT Ye JJ Alonso MN | 2010 | Immunol Cell Biol2010，88，6： | 1 |
| 10 | Radiotherapeutic man?agement of brain metastases: a systematic review and meta?analysis显示文摘 | Tsao MN lloyd NS Wong RK | 2005 | Cancer Treat Rev2005，31，： | 1 |
| 11 | Use of perfluorohexyloctane as a long-term internal tamponade agent in complicated retinal detachment surgery显示文摘 | Kirchhof B Wong D Meurs JV Hilgers RD Lois MN Schrage NF | 2002 | Am J Ophthalmol2002，130，2： | 1 |
| 12 | Supportive care guidelines group of cancer care ontario's program in evidence-based care clinical practice guideline on the optimal radiotherapeutic management of brain metastases显示文摘 | Tsao MN Lioyd NS Wong RK | 2005 | BMC Cancer2005，5，1： | 1 |
| 13 | Regulation of human Th9differentiation by type I interferons and IL-21 显示文摘 | Wong MT Ye JJ Alonso MN | 2010 | Immunol CellBiol2010，，： | 1 |
| 14 | Radiotherapeutic management of brain metastases:a systematic review and meta-analysis显示文摘 | Tsao MN Lloyd NS Wong RK | 2005 | Cancer Treat Rev2005，31，4： | 1 |
| 15 | THI, TH2, and TH17 cells instruct monocytes to differentiate into specialized dendritic cell subsets显示文摘 | Alonso MN Wong MT Zhang AL | 2011 | Blood2011，118，12： | 1 |
| 16 | Regulation of human Th9 dif-ferentiation by typeⅠinterferons and IL-21显示文摘 | Wong MT Ye JJ Alonso MN | 2010 | Immunol CellBiol2010，88，6： | 1 |
| 17 | Treatment of neuroendocrine tumours in adults with 131I-MIBG therapy显示文摘 | Bomanji JB Wong W Gaze MN | 2003 | Clin Oncol(R Coll Radiol)2003，15，4： | 1 |
| 18 | Radiofrequency catheter ablation in the treatment of supraventricular tachycardia in the elderly显示文摘 | Epstein LM Chiesa N Wong MN | 1994 | JACC1994，23，： | 1 |
| 19 | Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases 显示文摘 | Tsao MN Lloyd N Wong RK | 2012 | Cochrane Database Syst Rev2012，18，4： | 1 |
| 20 | Radiofrequency catheter ablation in the treatment of supraventricular tachycardia in the elderly显示文摘 | Epstein LM Chiesa N Wong MN | 1994 | J Am Coll Cardiol1994，23，6： | 1 |
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