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| 1 | CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells显示文摘In face of the everlasting battle toward COVID-19 and the rapid evolution of SARS-CoV-2,no specific and effective drugs for treating this disease have been reported until today.Angiotensin-converting enzyme 2(ACE2),a receptor of SARS-CoV-2,mediates the virus infection by binding to spike protein.Although ACE2 is expressed in the lung,kidney,and intestine,its expressing levels are rather low,especially in the lung.Considering the great infectivity of COVID-19,we speculate that SARS-CoV-2 may depend on other routes to facilitate its infection.Here,we first discover an interaction between host cell receptor CD147 and SARS-CoV-2 spike protein.The loss of CD147 or blocking CD147 in Vero E6 and BEAS-2B cell lines by anti-CD147 antibody,Meplazumab,inhibits SARSCoV-2 amplification.Expression of human CD147 allows virus entry into non-susceptible BHK-21 cells,which can be neutralized by CD147 extracellular fragment.Viral loads are detectable in the lungs of human CD147(hCD147)mice infected with SARS-CoV-2,but not in those of virus-infected wild type mice.Interestingly,virions are observed in lymphocytes of lung tissue from a COVID-19 patient.Human T cells with a property of ACE2 natural deficiency can be infected with SARS-CoV-2 pseudovirus in a dosedependent manner,which is specifically inhibited by Meplazumab.Furthermore,CD147 mediates virus entering host cells by endocytosis.Together,our study reveals a novel virus entry route,CD147-spike protein,which provides an important target for developing specific and effective drug against COVID-19. | Ke Wang Wei Chen Zheng Zhang Yongqiang Deng Jian-Qi Lian Peng Du Ding Wei Yang Zhang Xiu-Xuan Sun Li Gong Xu Yang Lei He Lei Zhang Zhiwei Yang Jie-Jie Geng Ruo Chen Hai Zhang Bin Wang Yu-Meng Zhu Gang Nan Jian-Li Jiang Ling Li Jiao Wu Peng Lin Wan Huang Liangzhi Xie Zhao-Hui Zheng Kui Zhang Jin-Lin Miao Hong-Yong Cui Min Huang Jun Zhang Ling Fu Xiang-Min Yang Zhongpeng Zhao Shihui Sun Hongjing Gu Zhe Wang Chun-Fu Wang Yacheng Lu Ying-Ying Liu Qing-Yi Wang Huijie Bian Ping Zhu Zhi-Nan Chen | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 9 |
| 2 | Sulfur isotopic composition of the Bainiuchang super-large Ag polymetallic deposit,Yunnan Province,China: Implications for the source of sulfur in ore-forming fluids显示文摘The Bainiuchang deposit in Yunnan Province, China, is located geographically between the Gejiu ore field and the Dulong ore field. In addition to >7000 t Ag reserves, the deposit possesses large-scale Pb, Zn, Sn reserves and a mass of dispersed elements (i.e., In, Cd, Ge, Ga, etc.). Based on systematic studies of sulfur isotopic composition, the authors conclude: The Bainiuchang deposit experienced two epochs of metallogenesis, i.e., the Middle-Cambrian sea-floor exhalative sedimentary metallogenic epoch and the Yanshanian magmatic hydrothermal superimposition metallogenic epoch. In the two metallogenic epochs, the δ34S values of sulfides were all near 0, showing a tendency of being enriched slightly in heavy sulfur. The δ34S values of sulfides in the early metallogenic epoch are within the range of 2‰–5‰ with a peak value range of 2‰–3‰ and an average of 3.0‰, and those of sulfides in the late metallogenic epoch are within the range of 2‰–6‰ with a peak value of 3‰–4‰ and an average of 3.9‰. For the single metallogenic epoch, sulfur in the ore-forming fluids in the early epoch already reached isotopic equilibrium and was derived mainly from underneath the magma chamber or basement metamorphic igneous rocks. Sulfur in the sulfides in the late epoch was derived mainly from magmatic hydrothermal fluids formed in the process of remelting of the basement metamorphic igneous rocks. | XIE Hongjing ZHU Chaohui ZHANG Qian WANG Dapeng FAN Liangwu | 2009 | Chinese Journal Of Geochemistry2009，28，3： | 7 |
| 3 | Physicochemical Control of the Early Permian Xiangshan Fe-Ti Oxide Deposit in Eastern Tianshan(Xinjiang),NW China显示文摘The Xiangshan mafic-ultramafic complex is one of the major Early Permian mafic-ultramafic intrusions in eastern Tianshan(Xinjiang, NW China), and consists of two major intrusive phases. The first intrusive phase is mainly gabbroic rocks hosting ilmenite mineralization, while the second intrusive phase is mainly lherzoilite associated with Ni-Cu sulfide mineralization. The Xiangshan ilmenite orebodies hosted in the Fe-Ti oxide-bearing gabbro occur along the contact between hornblende gabbros and leucogabbros. The hornblende gabbros and Fe-Ti oxide rich gabbros at Xiangshan are newly dated to be Early Permian(280.1 and 279.2 Ma, respectively). Major and trace element compositions of zircons and whole rocks from Xiangshan hornblende gabbro and Fe-Ti oxide gabbro have been measured by in situ excimer laser ablation ICP-MS. Zircon Ce^(4+)/Ce^(3+) ratios based on lattice-strain model and Ti-in-zircon temperatures of hornblende gabbro and Fe-Ti oxide gabbro of the Xiangshan complex are calculated to evaluate the physicochemical variations during the ilmenite mineralization. Whole-rock geochemistry and zircon trace element geochemistry suggest that Fe-Ti oxide gabbros were formed from a basaltic parent magma which had undergone a transfromation from being H_2O-rich to H_2O-poor. During the magmatic evolution, primitive, H_2O-poor basaltic melts may have been replenished into the system, increasing its solidus temperature and decreasing its oxygen fugacity and H_2O contents. This may have supperessed the Ti-rich poikilitic hornblende fractionation and promoted the plagioclase fractionation, which consequently concentrated the ore-forming components in the residual melts and generated the ilmenite mineralization. | Yu Shi Yuwang Wang Jingbin Wang Lutong Zhao Hongjing Xie Lingli Long Tao Zou Dedong Li Guochao Zhou | 2018 | Journal of Earth Science2018，29，3： | 6 |
| 4 | Fiber Bragg Grating (FBG) Sensors Used in Coal Mines显示文摘纤维布拉格栅栏(FBG ) 紧张传感器被用于在在 Dongtan 矿沿着号码 3203 煤采矿脸的废矿保留的网关的衬里的墙的压力变化的联机监视。结果证明有宽测量范围的 FBG 紧张传感器能在沿着废矿保留的网关的支持过程期间精确地测量压力变化并且能提供基础进一步优化支持结构并且决定沿着废矿保留的网关的支持计划。FBG 微地震的传感器在 Xinglong 矿被使用检测微地震的信号。信号受到欢迎并且分析了决定地点和微地震的事件警告的来源的精力水平。FBG 传感器和检测系统为微地震的察觉和地质的灾难察觉显示出一个重要潜力。 | Jinyu WANG Tongyu LIU Guangdong SONG Hongjing XIE Lianqing LI Xiaolin DENG Zhijie GONG | 2014 | Photonic Sensors2014，4，2： | 3 |
| 5 | Petrogenesis and Metallogenesis of the Niumaoquan Gabbroic Intrusion Associated with Fe-Ti Oxide Ores in the Eastern Tianshan, NW China显示文摘The Niumaoquan layered gabbroic intrusion is in the southern margin of the Central Asian Orogenic Belt in North Xinjiang, China, and hosts a Fe-Ti oxide deposit in its evolved gabbroic phases. In this paper, we report zircon U-Pb age, Sr-Nd-Hf isotopes, plagioclase chemistry, and whole-rock geochemistry of the Niumaoquan layered gabbroic intrusion. Zircon grains separated from an anorthosite sample analyzed by laser ablation inductively coupled plasma mass spectrometry yielded a concordia age of 314.7±0.74 Ma, indicating that the Niumaoquan ore-bearing gabbroic intrusion was emplaced during the Late Carboniferous. The olivine gabbro texture and plagioclase chemistry suggest that plagioclase was an early crystallized silicate phase that crystallized prior to olivine. Fractional crystallization and accumulation of plagioclase significantly controlled the evolution of the Niumaoquan gabbroic intrusion and contributed to the formation of anorthosite layers, causing metallogenic elements to become enriched in the residual melt. The Niumaoquan gabbroic intrusion is characterized by the enrichment of large ion lithophile elements and depletion of high field strength elements, positive zircon εHf(t) values(+2.1 to +12.2), positive εNd(t) values(+3.3 to +5.2), and low initial ^(87)Sr/^(86)Sr ratios(0.7039 to 0.7047), suggesting that the parental magma was produced by interactions between metasomatized lithospheric mantle and depleted asthenospheric melts at an early post-collision stage. The Fe-Ti oxide mineralization of the Niumaoquan intrusion benefited from interactions between depleted asthenospheric melts and lithospheric mantle, and fractional crystallization of abundant plagioclase and magnesian minerals. | SHI Yu WANG Yuwang WANG Jingbin XIE Hongjing MAO Qigui ZHAO Lutong LONG Lingli LI Dedong ZHOU Guochao | 2018 | Acta Geologica Sinica(English Edition)2018，92，5： | 3 |
| 6 | Exo-celiac liver in Glyptosternum maculatum显示文摘A unique structure in the fish of Glyptosternum maculatum(Regan)(Siluriformes:Sisoridae)is reported.It was identified as a part of the liver named 'exo-celiac liver'.This new organ is located between skin and muscle and connected with the celiac liver by a funiform tissue,'joint belt'.It has similar histological features and isozyme electrophoretogramic bands of lactate dehydrogenase,esterase,malate dehydrogenase and alcohol dehydrogenase as in the celiac liver.This unique organ has biological research value and could serve as an important tool for studying organogenesis and evolution. | Li Hongjing Xie Congxin Li Dapeng Chai Yi Liu Hongyan Fan Qixue Zhu Bangke | 2007 | Progress in Natural Science:Materials International2007，17，9： | 3 |
| 7 | Zircon SIMS U-Pb Age of the Shaxinan Melagabbro, Eastern Tianshan and Constraints on Fe-Ti-V Oxide Mineralization显示文摘Objective The late Paleozoic Fe-Ti-V oxide deposit of the eastern Tianshan is an important orthomagmatic deposit type in the Central Asia Orogenic Belt(CAOB).A series of Fe-Ti-V oxide deposits and mineralized mafic-ultramafic intrusions have been recognized recently,such as those in Hongliangzi,Weiya,Yaxi,Shaxinan and Shaxi on the Central Tianshan massif,and Niumaoquan on the | SHI Yu WANG Yuwang WANG Jingbin MAO Qigui XIE Hongjing ZHOU Guochao ZHU Jiangjian WEI Xiaofeng Lü Xiaoqiang | 2018 | Acta Geologica Sinica(English Edition)2018，92，5： | 2 |
| 8 | Determination of carnosine in Black-Bone Silky Fowl (Gallus gallus domesticus Brisson) and common chicken by HPLC显示文摘 | Yinggang Tian Mingyong Xie Weiya Wang Hongjing Wu Zhihong Fu Lin Lin | 2007 | European Food Research and Technology (-)2007，，1： | 1 |
| 9 | Polarons in a cylindrical quantum well wire with finite confining potential 显示文摘 | Xie Hongjing Liu Xiaoyan | 2006 | Superlattices and Microstructures2006，39，6： | 1 |
| 10 | Bound polaron in cylindrical quantum wires of polaron crystal 显示文摘 | Xie Hongjing Chen Chuanyu Ma Benkun | 2000 | Phys Rev B2000，61，7： | 1 |
| 11 | Polaron self energy and effective mass in a freestanding cylindrical quantum wire显示文摘 | Xie Hongjing | 2004 | Physica E2004，22，： | 1 |
| 12 | Transfer matrix method for the Frohlich electron-interface optical phonon interac- tion in multilayer coaxial quantum well wires显示文摘 | Zhang Li Xie Hongjing | 2004 | Int J of Mod Phys B2004，18，3： | 1 |
| 13 | Influence of both electric and magnetic fields on the polaron in a cylindrical quantum dot显示文摘 | Wang Ruiqiang Xie Hongjing Yu Youbin | 2004 | Int J Mod Phys B2004，18，2021： | 1 |
| 14 | Polar stationary phases for capillary electrochromatography显示文摘 | XIE Chuanhui FU Hongjing HU Jiwei | 2004 | Electrophoresis2004，25，23： | 1 |
| 15 | Late Triassic Magma Mixing and Fractional Crystallization in the Qingchengzi Orefield,Eastern Liaoning Province:Regional Petrogenetic and Metallogenic Implications显示文摘The Qingchengzi orefield is an important Pb-Zn-Au-Ag polymetallic orefield in NE Chi-na.The Indosinian magmatism has formed the Shuangdinggou batholith and the Xinling stock,as well as dikes of quartz monzonite porphyry and lamprophyre.According to petrographic characteristics,the Shuangdinggou intrusion can be divided into the main suite and the central suite.Zircon U-Pb dat-ing yielded crystallization ages of 215.0-220.9 Ma for these various Qingchengzi magmatic units,which are within analytical error and represent coeval magmatism.The Shuangdinggou main suite contains abundant mafic microgranular enclaves(MMEs)and shows features of magma mixing.Geochemically,the major oxide contents of the MMEs and their quartz monzonite host show well-defined linear frac-tionation trends.The REE and trace element patterns of the MMEs and their host are similar,which demonstrates certain degree of geochemical homogenization between the two during magma mixing.The Shuangdinggou main suite shares similar geochemical characteristics with typical high Ba-Sr gra-nites(Ba=1082 ppm-2051 ppm,Sr=803 ppm-886 ppm),and was likely originated from the mixing between a melt derived from partial melting of the thickened lower crust and the enriched mantle.The central suite was likely formed by fractional crystallization of the main-suite magma.The Xinling in-trusion may represent a branch of the Shuangdinggou intrusion and has the same genesis as the central suite.The quartz monzonite porphyries geochemically mimic the Shuangdinggou main suite,and may also be an epioic facies of the Shuangdinggou intrusion.The MMEs and lamprophyres may have been derived from incomplete magma mixing.Formation of the Pb-Zn and Au-Ag deposits in the Qing-chengzi orefield may have been related to the granite/quartz monzonite porphyries near the Shuangdinggou intrusion,which were formed by magma mixing and fractional crystallization. | Hongjing Xie Yuwang Wang Dedong Li Guochao Zhou Zhichao Zhang | 2021 | Journal of Earth Science2021，32，1： | 1 |
| 16 | Surface and interface optical phonon and electron-phonon interaction in maltishell spherical system显示文摘 | Zhang Li Xie Hongjing Chen Chuanyu | 2002 | Eur Phys J B2002，27，： | 1 |
| 17 | Dielectric loss enhancement induced by the microstructure of CoFe_(2)O_(4) foam to realize broadband electromagnetic wave absorption显示文摘CoFe_(2)O_(4)has been widely used for electromagnetic wave absorption owing to its high Snoek limit,high anisotropy,and suitable saturation magnetization;however,its inherent shortcomings,including low dielectric loss,high density,and magnetic agglomeration,limit its application as an ideal absorbent.This study investigated a microstructure regulation strategy to mitigate the inherent disadvantages of pristine CoFe_(2)O_(4)synthesized via a sol–gel auto-combustion method.A series of CoFe_(2)O_(4)foams(S0.5,S1.0,and S1.5,corresponding to foams with citric acid(CA)-to-Fe(NO_(3))_(3)·9H_(2)O molar ratios of 0.5,1.0,and 1.5,respectively)with two-dimensional(2D)curved surfaces were obtained through the adjustment of CA-to-Fe^(3+)ratio,and the electromagnetic parameters were adjusted through morphology regulation.Owing to the appropriate impedance matching and conductance loss provided by moderate complex permittivity,the effective absorption bandwidth(EAB)of S0.5 was as high as 7.3 GHz,exceeding those of most CoFe_(2)O_(4)-based absorbents.Moreover,the EAB of S1.5 reached 5.0 GHz(8.9–13.9 GHz),covering most of the X band,owing to the intense polarization provided by lattice defects and the heterogeneous interface.The three-dimensional(3D)foam structure circumvented the high density and magnetic agglomeration issues of CoFe_(2)O_(4)nanoparticles,and the good conductivity of 2D curved surfaces could effectively elevate the complex permittivity to ameliorate the dielectric loss of pure CoFe_(2)O_(4).This study provides a novel idea for the theoretical design and practical production of lightweight and broadband pure ferrites. | Bin Shi Hongsheng Liang Zijun Xie Qing Chang Hongjing Wu | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，7： | 0 |
| 18 | Optimizing impedance matching by a dual-carbon Co-regulation strategy of Co_(3)O_(4)@rGO/celery stalks derived carbon composites for excellent microwave absorption显示文摘Both macroscopic composition and microstructure should be considered for reasonable microwave ab-sorbent designing.In this study,Co_(3)O_(4)@reduced graphene oxide(rGO)/Celery stalks derived carbon(CDC)was prepared by loading Co_(3)O_(4) particles into rGO and biomass-derived carbon mixture through oxidation precipitation.By changing the mass ratio of rGO to CDC,the dielectric and impedance matching proper-ties of the composites can be easily regulated.The RL min value of Co_(3)O_(4)@rGO/CDC_(13) composite(weight ratio for rGO:CDC is 1:3)reaches-84.3 dB with a thickness of 4.6 mm,and the widest effective band-width can be obtained at 4.5 GHz with a matching thickness of 2.8 mm.The Co_(3)O_(4)@rGO/CDC_(13) compos-ite with multiple components(Co_(3)O_(4),CDC,rGO)and 3D net structure produces magnetic/dielectric loss combinations,interfacial polarization,and multiple reflections and scattering,and the CDC with half tube and half sheet structure is conducive to the optimization of impedance matching.The strategy of co-regulating dielectric properties of materials with double carbon provides a novel pathway for the prepa-ration of lightweight,low-cost,and high-performance absorbers. | Xiubo Xie Yukun Wang Xueqin Sun Heshan Wang Ronghai Yu Wei Du Hongjing Wu | 2023 | Journal of Materials Science & Technology2023，，2： | 0 |
| 19 | Geochronology and geochemistry of magmatic rocks in the Dongzi–Changhanboluo Pb–Zn ore district in Chifeng,Inner Mongolia,and their relationship with metallogenesis显示文摘Bulk-rock elements,isotopes,and zircon U–Pb ages are reported for magmatic rocks in the Dongzi–Changhanboluo Pb–Zn ore district in Chifeng,Inner Mongolia,China.Zircon U–Pb dating identified four stages of magmatism:Late Silurian gabbroic diorite(*420 Ma),Middle Permian monzonite(*274 Ma),Late Jurassic quartz porphyry and ignimbrite,breccia tuff(153–158 Ma)and Early Cretaceous andesitic porphyrite(*127 Ma).Integrating field observations,geochronology,and element and isotope geochemistry indicated a complex petrogenetic history of the magmatic rocks.The gabbroic diorite may have been sourced from EM1-type mantle.The source of the monzonite may have been mantle metasomatized by melt from the subducting plate.The Jurassic volcaniclastic rocks formed in a medium-pressure,high-temperature environment,possibly in the background of crustal thickening in a syncollisional stage and an early postcollisional stage.During this process,shaly sedimentary rocks were brought into the deep crust and heated,followed by the rapid isostatic uplift of the crust,which caused partial melting of the sedimentary rocks.Quartz monzonite porphyry and quartz porphyry formed by partial melting of mantle metasomatized by subducted sediments,but the quartz porphyry experienced high-degree differentiation and evolution.The andesitic porphyrite has characteristics similar to those of Permian monzonite,indicating that its source area was also the zone of mantle metasomatized by subducted sediment.The late Silurian and Permian magmatic rocks in this area most likely formed against a continental arc background related to the subduction of the Paleo-Asian Ocean Plate beneath the North China Plate.The Late Jurassic magmatic rocks suggest that the northern margin of the North China Craton may have been in a postcollisional setting during the Late Jurassic,with no obvious crustal thinning.The Cretaceous andesitic porphyrite may have formed against the background of lithospheric extension and thinning.According to the comprehensive analysis of geological characteristics,diagenetic and metallogenic epochs,and Pb isotope data,the formation of ore bodies in the Dongzi–Changhanboluo ore district was closely related to the Jurassic quartz porphyry. | Hongjing Xie Yuwang Wang Yunguo Zhang Wei Jiang Zhiyuan Sun | 2020 | Acta Geochimica2020，39，5： | 0 |
| 20 | CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells显示文摘In face of the everlasting battle toward COVID-19 and the rapid evolution of SARS-CoV-2,no specific and effective drugs for treating this disease have been reported until today.Angiotensin-converting enzyme 2(ACE2),a receptor of SARS-CoV-2,mediates the virus infection by binding to spike protein.Although ACE2 is expressed in the lung,kidney,and intestine,its expressing levels are rather low,especially in the lung.Considering the great infectivity of COVID-19,we speculate that SARS-CoV-2 may depend on other routes to facilitate its infection.Here,we first discover an interaction between host cell receptor CD147 and SARS-CoV-2 spike protein.The loss of CD147 or blocking CD147 in Vero E6 and BEAS-2B cell lines by anti-CD147 antibody,Meplazumab,inhibits SARSCoV-2 amplification.Expression of human CD147 allows virus entry into non-susceptible BHK-21 cells,which can be neutralized by CD147 extracellular fragment.Viral loads are detectable in the lungs of human CD147(hCD147)mice infected with SARS-CoV-2,but not in those of virus-infected wild type mice.Interestingly,virions are observed in lymphocytes of lung tissue from a COVID-19 patient.Human T cells with a property of ACE2 natural deficiency can be infected with SARS-CoV-2 pseudovirus in a dosedependent manner,which is specifically inhibited by Meplazumab.Furthermore,CD147 mediates virus entering host cells by endocytosis.Together,our study reveals a novel virus entry route,CD147-spike protein,which provides an important target for developing specific and effective drug against COVID-19. | Ke Wang Wei Chen Zheng Zhang Yongqiang Deng Jian-Qi Lian Peng Du Ding Wei Yang Zhang Xiu-Xuan Sun Li Gong Xu Yang Lei He Lei Zhang Zhiwei Yang Jie-Jie Geng Ruo Chen Hai Zhang Bin Wang Yu-Meng Zhu Gang Nan Jian-Li Jiang Ling Li Jiao Wu Peng Lin Wan Huang Liangzhi Xie Zhao-Hui Zheng Kui Zhang Jin-Lin Miao Hong-Yong Cui Min Huang Jun Zhang Ling Fu Xiang-Min Yang Zhongpeng Zhao Shihui Sun Hongjing Gu Zhe Wang Chun-Fu Wang Yacheng Lu Ying-Ying Liu Qing-Yi Wang Huijie Bian Ping ZhuZhi-Nan Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，1： | 0 |
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