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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Micronuclei in Nasal Mucosa, Oral Mucosa and Lymphocytes in Students Exposed to Formaldehyde Vapor in Anatomy Class显示文摘The frequency of micronuclei (MN) in cells of the nasal mucosa, oral mucosa and in lym-phocytes was evaluated for 25 students in anatomy classes exposed to formaldehyde (FA) overan 8-week period. Each student served as his or her own control. The time-weighted averageconcentration (TWA) of fOrmaldehyde in anatomical laboratories and in students’ dormitorieswas 0. 508 ± 0. 299 mg/m3 and 0. 012 ± 0. 0025mg/m3, respectively. A higher frequency ofmicronuclei was observed in nasal and oral exfoliative cells after formaldehyde exposure (3. 85± 1. 48 vs 1 .20± 0. 676 and 0. 857 ± 0. 558 vs 0. 568 ± 0. 317, paired-t test: P< 0. 001and P < 0. 01, respectively). No significant increase in the frequency of lymphocyte micronu-clei was found after formaldehyde exposure (P >0. 05 ). The present study shows that nasalmucosa cel1s exposed through respiration are the chief target of FA-induced genotoxic | YING CHEN -JlANG YAN WEN-SHENG ZHAO MEI-YING YE XIAO-LEI XIE HONG YIN SHU-YI ZHU XIAN-SHU(Department of Environmental Health, n Dgurtment of Anatomy,Tongji the ical University, Wuhan, China)(Department of Public Health, Wengzhou theical Chllege, Ch | 1997 | Biomedical and Environmental Sciences1997，10，4： | 7 |
| 3 | Discovering the roles of subsurface microorganisms: Progress and future of deep biosphere investigation显示文摘The discovery of the marine 'deep biosphere'-microorganisms living deep below the seafloor-is one of the most significant and exciting discoveries since the ocean drilling program began more than 40 years ago. Study of the deep biosphere has become a research frontier and a hot spot both for geological and biological sciences. Here, we introduce the history of the discovery of the deep biosphere, and then we describe the types of environments for life below the seafloor, the energy sources for the living creatures, the diversity of organisms within the deep biosphere, and the new tools and technologies used in this research field. We will highlight several recently completed Integrated Ocean Drilling Program Expeditions, which targeted the subseafloor deep biosphere within the crust and sediments. Finally, future research directions and challenges of deep biosphere investigation towards uncovering the roles of subsurface microorganisms will be briefly addressed. | WANG FengPing LU ShuLin ORCUTT Beth N XIE Wei CHEN Ying XIAO Xiang EDWARDS Katrina J | 2013 | Chinese Science Bulletin2013，58，4： | 6 |
| 4 | Study on the magnetic compression of intense relativistic electron beams in a converging magnetic guide field 显示文摘 | Liu G Z Liu N Q Xie X | 1994 | Acta Physica Sinica1994，3，1： | 2 |
| 5 | Synthesis and structural characterization of several tris(2-methyl-2-phenylpropyl)tin carboxylates contanining germanium显示文摘 | Fang X N Song X Q Xie Q L | | 0，，： | 2 |
| 6 | STUDIES ON DERIVATIVES OF CLERODANE DITERPENOIDSFROM AJUGA DECUMBENS显示文摘STUDIESONDERIVATIVESOFCLERODANEDITERPENOIDSFROMAJUGADECUMBENSHuandingCHEN(InstituteofElemento-OrganicChemistry,NankaiUniversi... | Chen, HM Xie, N Min, ZD | 1996 | Chinese Chemical Letters1996，7，6： | 2 |
| 7 | Risk for esophageal neoplasia in B arrett’s esophagus patients with mucosal changes indefinite for dysplasia显示文摘 | Bela Horvath Prabhdeep Singh Hao Xie Prashanthi N Thota Daniela S Allende Rish K Pai Deepa T Patil Thomas P Plesec John R Goldblum Xiuli Liu | 2015 | J Gastroenterol Hepatol2015，，： | 2 |
| 8 | Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17显示文摘 | Aggarwal S Ghilardi N Xie MH | 2003 | J Biol Chem2003，278，3： | 1 |
| 9 | Gain-of-function mutation of FGFR3 results in impaired fracture healing due to inhibition of chondrocyte differentia' tion显示文摘 | Su N Yang J Xie Y | 2008 | Biochem Biophy Res Commun2008，376，3： | 1 |
| 10 | Detection of small objects in clutter using a GA-RBF neural network显示文摘 | Leung H Dubash N Xie N | 2002 | IEEE Trans AES2002，38，1： | 1 |
| 11 | Joint optimization of preventive maintenance and inventory control in a production line using simulation显示文摘 | Rezg N Xie X Mati Y | 2004 | International Journal of Production Research2004，42，10： | 1 |
| 12 | The clinical effec tiveness of negative pressure wound therapy: a sys tematic review显示文摘 | Xie X McGregor M Dendukuri N | 2010 | Wound Care2010，19，11： | 1 |
| 13 | Sphingosinel-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells显示文摘 | Xie JH Nomura N Koprak SL | | 0，，07： | 1 |
| 14 | Discovering urban functional zones using latent activity trajectories显示文摘 | Yuan N J Zheng Y Xie X | 2015 | IEEE Transactions on Knowledge and Data Engineering2015，27，3： | 1 |
| 15 | Involvement of the blood-brain harrier openingin cognitive decline in aged rats followingortho- pedic surgery and high eoncentrationof sevoflurane inhalation 显示文摘 | HU N GUO D XIE K | 2014 | Brain Research2014，1551，： | 1 |
| 16 | Design and assembly of antiCD16 ScFv antibody with two different linker peptides 显示文摘 | Feng J Xie Z Guo N | 2003 | J Immunol Methods2003，282，12： | 1 |
| 17 | Interleukin-23 promotes a distinct CD4 T-cell activation state charactize by the production of interleukin-17显示文摘 | Aggarwal S Ghilardi N Xie MH | 2003 | J Biol chem2003，27，8： | 1 |
| 18 | Optimization of Compact Heat Exchangers by a Genetic Algorithm 显示文摘 | XIE G N Sunden B WANG Q W | 2008 | Applied Thermal Engineering2008，28，89： | 1 |
| 19 | Earnings management and corporate governance: the role of the board and the audit committee 显示文摘 | Xie B Davidson III W N DaDatt P J | 2003 | Journal of Corporate Finance2003，9，： | 1 |
| 20 | Strong green emission from a-SiAlON activated by divalent ytterbium under blue light irradiation 显示文摘 | Xie R J Hirosaki N Mitomo M Uheda K Suehiro T Xu X Yamamoto Y Sekiguchi T | 2005 | Journal of Physical Chemistry B2005，109，： | 1 |
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