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| 1 | Therapeutic effects of Clostridium butyricum on experimental colitis induced by oxazolone in rats显示文摘AIM:To evaluate the therapeutic effects of a probiotic supplement(Clostridium butyricum,CGMCC0313)in a chemically-induced rat model of experimental colitis. METHODS:An experimental ulcerative colitis model was established by rectal injection of oxazolone into the colon of 40 Wistar rats randomly divided into four groups.The positive control group was sacrificed 3 d after colitis onset.The remaining groups were fed daily with either 2 mL of C.butyricum(2.3×1011 CFU/L), 2 mL of mesalamine(100 g/L),or 1 mL of sodium butyrate(50 mmol/L)for 21 d.The animals’body weight, behavior,and bowel movements were recorded weekly. After sacrifice,visual and microscopic observations of pathological changes of colon tissue were made,body weight and wet colon mass index were measured and recorded,and serum levels of interleukin-23(IL-23) and TNF-αwere measured using ELISA.Expression of calcitonin gene-related peptide in colon tissue was measured by RT-PCR.Finally,changes in rat intestinal microflora status were measured in all groups. RESULTS:We found that treatment with C.butyricum lowered the serum levels of both IL-23 and tumor necrosis factor-α(TNF-α)with similar or even better efficiency than that of mesalamine or sodium butyrate. The rat intestinal flora appeared to recover more quickly in the group treated with C.butyricum than in the mesalamine and sodium butyrate groups.Finally,we found that the expression level of calcitonin gene related peptide was elevated in colon tissue in the sodium butyrate treated group but not in the C.butyricum or mesalamine treated groups,indicating a sensitization of colon following sodium butyrate treatment.CONCLUSION:In our experimental colitis model, treatment with C.butyricum CGMCC0313,a probiotic supplement,is at least as efficient as treatment with mesalamine. | Hai-Qiang Zhang Tomas T Ding Jun-Sheng Zhao Xin Yang Hai-Xia Zhang Juan-Juan Zhang Yun-Long Cui | 2009 | World Journal of Gastroenterology2009，15，15： | 19 |
| 2 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 3 | 施万细胞在阴茎和外周神经再生中的作用显示文摘施万细胞(SCs)是外周神经系统中主要的胶质细胞。施万细胞最终发育为形成髓鞘的细胞和不形成髓鞘的细胞,前者包绕直径较大的神经,后者则包绕直径较小的神经。他们在神经损伤后的再生中发挥重要作用,包括海绵体神经损伤导致的勃起功能障碍(ED)。尽管前列腺癌根治术手术技术有所提高,但是仍有相当一部分患者术后出现ED。这是由于术中牵拉损伤或局部炎症反应改变了自主神经的微环境,最终导致终末器官-阴茎的病理生理改变。该综述目的是总结现有的如下方面相关文献:(1)外周神经特别是阴茎神经中施万细胞的起源和发育;(2)外周神经特别是阴茎神经损伤后的Wallerian变性和施万细胞的可塑性;(3)施万细胞如何通过分泌神经生长因子促进神经再生;(4)以施万细胞作为治疗靶点促进神经再生的技术。我们搜索了Pubmed,发现了为数众多的与上述主题相关的动物实验和人体研究,这提示施万细胞有望成为神经源性ED治疗的新靶点。 | Lin Wang Melissa T Sanford Zhongcheng Xin Guiting Lin Tom F Lue | 2015 | Asian Journal of Andrology2015，17，5： | 7 |
| 4 | Microstructure and Wear Behaviour of Laser-Induced Thermite Reaction Al_2O_3 Ceramic Coatings on Pure Aluminum and AA7075 Aluminum Alloy显示文摘Wear-resistant laser-induced thermite reaction Al_2O_3 ceramic coatings can be fabricated on pure Al and AA7075 aluminum alloy by laser cladding(one-step method)and laser cladding followed by laser re-melting(two-step method)using mixed powders CuO-Al-SiO_2 in order to improve the wear properties of aluminum and aluminum alloy,respectively.The microstructure of the coatings was characterized by scanning electron microscopy(SEM)and X-ray diffraction(XRD).The wear resistance of the coatings was evaluated under dry sliding wear test condition at room temperature.Owing to the presence of hardα-Al_2O_3 andγ-Al_2O_3 phases,the coatings exhibited excellent wear resistance.In addition,the wear resistance of the coatings fabricated by two-step method is superior to that of the coatings fabricated by one-step method. | 黄开金 LIN Xin XIE Changsheng T M Yue | 2008 | Journal of Wuhan University of Technology(Materials Science)2008，23，1： | 4 |
| 5 | Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8^+ T cells during pregnancy显示文摘Listeria monocytogenes (Lm ) 为发展中的胎儿在怀孕和疾病的后果期间是有为全身的母亲的感染的唯一的倾向的一个细胞内部的细菌。给与出生前的 Lm 感染联系的高死亡,为在怀孕的极其脆弱的经期期间扩充保护的免疫的策略着急地被需要。此处,保护由在对随后的剧毒的 Lm 出生前的感染的怀孕被评估以前,管理的稀释 Lm 交谈了。因为显著地更多的细菌从母亲的纸巾被恢复,我们证明对在非怀孕的老鼠的第二等的 Lm 感染的保护严厉地在 allogeneic 怀孕期间被节制,尽管有病原体特定的 CD8 + T 房间的数字、功能的保藏。更重要地,因为各在怀孕和天真的怀孕控制以前与稀释 Lm 接种的老鼠在怀孕期间在 Lm 感染以后从单个 concepti 显示出近完全的胎儿的再吞和病原体恢复, preconceptual priming 不在 utero 侵略或胎儿的消耗量免于。显著地,对有在 allogeneic 怀孕的 preconceptual priming 的出生前的 Lm 感染的保护的缺乏在 syngeneic 怀孕期间被恢复。因此,母亲胎儿的抗原不和在出生前的 Lm 感染以后对胎儿的复杂并发症支配 preconceptual 种痘的低效率,尽管有病原体特定的 CD8 + T 房间的数字、功能的保藏。 | Dayna R Clark Vandana Chaturvedi Jeremy M Kinder Tony T Jiang Lijun Xin James M Ertelt Sing Sing Way | 2014 | Cellular & Molecular Immunology2014，11，6： | 3 |
| 6 | Correlation of Bmi-l expression and telomerase activity in human ovarian cancer显示文摘 | Zhang FB Sui LH Xin T | 2008 | Br 1 Biomed Sci2008，65，4： | 1 |
| 7 | Mechanisms of apoptosis in rat cerebellar granule cells induced by hydroxyl radicals and the effects of EGb761 and its constituents显示文摘 | Xin W Wei T Chen C | 2000 | Toxicology2000，148，23： | 1 |
| 8 | Deep desulfurization of model gasoline by adsorption on mesoporous CeMCM-41 显示文摘 | KE T XIN H | 2010 | Pet Sci Technol2010，28，6： | 1 |
| 9 | CD147, MMP9 expression and clinical significance of basal-like breast cancer 显示文摘 | Liu Y Xin T Jiang QY | 2013 | Med Oneol2013，30，1： | 1 |
| 10 | Anti-tumor effect of non-steroidal anti-inflammatory drugs on human ovarian cancers显示文摘 | Yokoyama Y Shigeto T | 2007 | Pathol Oncol Res2007，13，4： | 1 |
| 11 | Mechanisms of apoptosls in rat cerebellar granule cells induced by hydroxyl radicals and the effects of EGb761 and its constituents 显示文摘 | Xin W Wei T Chen C | 2000 | Toxicology2000，148，23： | 1 |
| 12 | Super food Lyciumbarbarum ( Solanaceae ) traceability via an internaltranscribed spacer 2 barcode 显示文摘 | Xin T Y Yao H Gao H H | 2013 | Food Res Int2013，54，2： | 1 |
| 13 | Regioregular poly(3- pentylthiophene) : synthesis, self-assembly of nanowires, high-mobility field-effect transistors, and efficient photo- voltaic cells 显示文摘 | Wu P T Xin H Kim F S | 2009 | Macromolecules2009，42，22： | 1 |
| 14 | A comparative study on IrO2-Ta2O5coated titanium electrodes prepared with different methods显示文摘 | Xu L K Xin Y L Wang J T | 2009 | Electrochim Acta2009，54，6： | 1 |
| 15 | Synthesis, characterization, and antibacterial activity of N, O-quaternary ammonium chitosan显示文摘 | Xu T Xin M Li M | 2011 | Carbohydrate Research2011，346，15： | 1 |
| 16 | Dynamic changes of transcript profiles after fertilization are associated with de novo transcription and maternal elimination in tobacco zygote, and mark the on- set of the maternal-to-zygotic transition 显示文摘 | Zhao J Xin H Qu L Ning J Peng X Yan T Ma L Li S Sun MX | 2011 | Plant J2011，65，： | 1 |
| 17 | Expression of survivin in invasive pituitary adenoma显示文摘 | Zhang YC Gao J Xin T | 2008 | Saudi Med J2008，29，11： | 1 |
| 18 | Effect of SiO2 on densification and microstructure development in Nd:YAG transparent ceramics 显示文摘 | STEVENSON A J LI Xin MART1NEZ M A ANDERSON J M SUCHY D L KUPP E R DICKEY1 Z C MUELLER K T MESSING G L | 2011 | J Am Ceram Soc2011，94，： | 1 |
| 19 | New edge-directed interpolation显示文摘 | Xin L Michae T O | 2001 | IEEE Trans- actions on Image Processing2001，10，10： | 1 |
| 20 | CD147, MMP-9 expression and clinical significance of basal-like breast cancer显示文摘 | Liu Y Xin T Jiang QY | 2013 | Med Oncol2013，30，1： | 1 |
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