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| 1 | The crustal structures of the central Longmenshan along and its margins as related to the seismotectonics of the 2008 Wenchuan Earthquake显示文摘In 2010,a 500-km-long wide-angle reflection/refraction seismic profile was completed,running northwest from the central Sichuan Basin.This profile orthogonally crosses the meizoseismal area of great Wenchuan earthquake of 12 May 2008,which occurred in the central part of the Longmenshan.The profile also passes through the northwestern Sichuan Plateau,along which a new deep seismic sounding observation system was set up that was much improved over previous datasets and enabled abundant observations to be recorded.Seismic wave phase records that reflect the structural characteristics of different tectonic blocks,especially the complicated phase features associated with the Wenchuan earthquake,were calculated and analyzed in detail.A 2D crustal P-wave velocity model for the orogenic belt in the central Longmenshan and its margins was determined,and crustal structure differences between the stable Sichuan Basin and the thickened northwestern Sichuan Plateau were characterized.Lithological variations within the upper and lower crust in the interior of the plateau,especially a great velocity decrease and plastic rheological properties associated with strong lithologic weakening in lower crust,were detected.From west to east in the lower crust beneath the orogenic belt lying between the Sichuan Basin and the northwestern Sichuan Plateau,a giant shovel-like upwelling is observed that dips gently in the lower part and at higher angles in the upper part;this is inferred to be related to the fault systems in the central Longmenshan.An upwelling in the upper-middle crust along the eastern margin of the orogenic belt is associated with steeply dipping thrusts that strongly uplift the upper crust and crystalline basement beneath a central fault system in the Longmenshan.The data,combined with an understanding of the regional tectonic stress field and previous geological results,enable a discussion of basin-and-range coupling,orogenic tectonics,the crustal fault system,and the seismogenic tectonic environment of the central Longmenshan along the eastern margin of the Qinghai-Tibet Plateau. | JIA ShiXu LIU BaoJin XU ZhaoFan LIU Zhi FENG ShaoYing ZHANG JianShi LIN JieYan TIAN XiaoFeng LIU QiaoXia GUO WenBin | 2014 | Science China Earth Sciences2014，57，4： | 26 |
| 2 | Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot. | Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 17 |
| 3 | Deep seismic sounding data reveal the crustal structures beneath Zoigê basin and its surrounding folded orogenic belts显示文摘Songpan-Garze massif is located at the turning position of tectonics from the nearly west-east direction to the nearly north-south direction in the northeastern margin of Tibetan Plateau,with Zoigê basin in the centre of the massif.In this paper,we build a crustal structure model of Zoigê basin and its surrounding folded orogenic belts using the deep seismic sounding data in this region.We also discuss structures and properties of the basement in Zoigê basin,tectonic relations between Zoigê upland basin and its surrounding folded orogenic belts,crustal deformation and thickening in the northeastern margin of Tibetan Plateau,and decoupling and relaxing processes in the crust.The results indicate that a special 'Mesozoic basement' is formed of Triassic rocks with high density (2.65-2.75 g/cm3) and high velocity (5.6 km/s) in Zoigê basin.Songpan-Garze tectonic massif was transformed into two types of tectonic units with different crustal structures,i.e.,relatively stable Zoigê upland basin and active folded orogenic belts around the basin,in the course of the crustal material of Tibetan Plateau flowing eastward and obstructed by surrounding stable blocks.The thickening of the crust in the northeastern margin of Tibetan Plateau mainly occurred in the mid and lower crust,and the structure characterized by low velocities and multiple reflectors obviously appears in the folded orogenic belts around Zoigê basin.It implies that the mid and lower crust underwent a strong tectonic deformation in the folded orogenic areas.The thickness of the crust is about 50 km in Zoigê basin and the folded orogenic belts at the both southern and northern sides of Zoigê basin.The 'Mountain root' cannot be identified.It is inferred that during the later orogenic period the eastwards flowing deep materials moved clockwise along the relatively relaxing southern side around the eastern tectonic knot under the obstructing of surrounding rigid massifs,and it resulted in the strong stretching action of the folded orogenic belts around Zoigê basin. | JIA ShiXu,ZHANG XianKang,ZHAO JinRen,WANG FuYun,ZHANG ChengKe,XU ZhaoFan,PAN JiShun,LIU Zhi,PAN SuZhen & SUN GuoWei Geophysical Exploration Center,China Earthquake Administration,Zhengzhou 450002,China | 2010 | Science China Earth Sciences2010，53，2： | 11 |
| 4 | Ablative fractional CO_(2)laser surgery improving sleep quality,pain and pruritus in adult hypertrophic scar patients:a prospective cohort study显示文摘Background:Poor sleep quality is associated with a decrease in quality of life in patients with major burn scars,combined with pruritus and pain.Few interventions have been reported to improve the sleep quality of patients with scars.In the current prospective cohort study,we investigated the efficacy of CO_(2)-ablative fractional laser(AFL)surgery vs conventional surgery in post-burn patients with hypertrophic scars with sleep quality as the primary study outcome.Methods:In total 68 consecutive patients undergoing scar surgical treatment were recruited,including a CO_(2)-AFL surgery cohort(n=35)and a conventional surgery cohort(n=33).A subgroup from the AFL cohort was selected.Sleep quality,pain and pruritus were evaluated.Multiple linear regression analyses were performed to reveal the effect of CO_(2)-AFL surgery.Results:The CO_(2)-AFL surgery cohort had significantly lower Pittsburgh sleep quality index(PSQI)global scores than the conventional surgery cohort after the last surgical treatment.In the subgroup of patients receiving hardware sleep monitoring,CO_(2)-AFL markedly increased deep sleep time,deep sleep efficiency and reduced initial sleep latency.Compared to the conventional surgery cohort,the CO_(2)-AFL cohort presented significantly lower pain and pruritus scores.Correlation analysis showed pain and pruritus were significantly associated with PSQI scores,and there were also significant correlations between pain and pruritus scores.Multiple linear regression analysis showed that surgery method was negatively linearly correlated with visual analog scale(VAS)pain score,brief pain inventory(BPI)total,VAS pruritus score,5-D itch scale total,four-item itch questionnaire(FIIQ)total and PSQI total.Conclusions:CO_(2)-AFL surgery significantly improved sleep quality and reduced pain and pruritus of hypertrophic scar patients.The alleviation of sleep disorder was associated with improvement of deep sleep quality including deep sleep time and deep sleep deficiency.Trial registration:The Chinese Clinical Trial Registry(ChiCTR200035268)approved retrospectively registration on 5 Aug 2020. | Kaiyang Lv Huazhen Liu Haiting Xu Caixia Wang Shihui Zhu Xiaozhen Lou Pengfei Luo Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 4 |
| 5 | Investigation of plateau basin crustal structures and thickening mechanisms in the northeastern margin of the Tibetan plateau显示文摘This paper uses deep seismic sounding (DSS) data to contrast and analyze the crustal structures of three plateau basins (Songpan-Garze, Qaidam, Longzhong) in the northeastern margin of the Qinghai-Xizang (Tibetan) plateau, as well as two stable cratonic basins (Ordos, Sichuan) in its peripheral areas. Plateau basin crustal structures, lithological variations and crustal thickening mechanisms were investigated. The results show that, compared to the peripheral stable cratonic basins, the crystalline crusts of plateau basins in the northeastern margin are up to 10-15 km thicker, and the relative medium velocity difference is about 5% less. The medium velocity change in crustal layers of plateau basin indicates that the upper crust undergoes brittle deformation, whereas the lower crust deforms plastically with low velocity. The middle crust shows a brittle-to-plastic transition zone in this region. Thickening in the lower crust (about 5-10 km), and rheological characteristics that show low- medium velocity (relatively reduced by 7%), suggest that crustal thickening mainly takes place in lower crust in the northeastern margin of the Tibetan plateau. The crust along the northeastern margin shows evidence of wholesale block movement, and crustal shortening and thickening seem to be the main deformation features of this region. The GPS data show that the block motion modes and crustal thickening in the Tibetan plateau is closely related to the peripheral tectonic stress field and motion direction of the Indian plate. The Mani-Yushu- Xianshuihe fold belt along the boundary between the Qiangtang block and the Bayan Har block divides the different plateau thickening tectonic environments into the middle-western plateau, the northeastern margin and the southeastern plateau. | Shixu Jia Zhaofan Xu Zhi Liu Jianshi Zhang Baofeng Liu Jiyan Lin Wenbin Guo | 2012 | Earthquake Science2012，25，5： | 1 |
| 6 | Effect ofgrape seed proanthocyanidin extracts on methylmercury-induced neurotoxicity in rats显示文摘 | YANG Haibo XU Zhaofan LIU Wei | 2012 | Biol Trace Elem Res2012，147，13： | 1 |
| 7 | Knockdown of Burton’s tyrosine kinase confers potent protection against sepsis-induced acute lung injury显示文摘 | Panyu Zhou Bing Ma Shuogui Xu Shijie Zhang Hongtai Tang Shihui Zhu Shichu Xiao Daofeng Ben Zhaofan Xia | 2014 | Cell Biochemistry and Biophysics2014，，2： | 1 |
| 8 | Re-expansion pulmonary edema post-pneumothorax显示文摘To the Editor Re-expansion pulmonary edema(REPE)is an uncommon complication that occurs in patients suffering from lung collapse,especially in cases of extensive and long term pneu-mothorax or pleural effusion.After thoracentesis or thoracic tube drainage is carried out,the collapsed lungs can be re-expanded and acute lung edema occurs in unilateral or even bilateral lungs within a short time.Although the reported incidence of REPE is<1%[1],it can have life-threatening consequences,as reported in some studies[2].In this article,we present the case of a young male patient who developed REPE after suffering traumatic pneumothorax. | He Fang Long Xu Feng Zhu Zhaofan Xia | 2020 | Burns & Trauma2020，8，1： | 0 |
| 9 | JAM-A facilitates hair follicle regeneration in alopecia areata through functioning as ceRNA to protect VCAN expression in dermal papilla cells显示文摘The dermal papilla cells in hair follicles function as critical regulators of hair growth.In particular,alopecia areata(AA)is closely related to the malfunctioning of the human dermal papilla cells(hDPCs).Thus,identifying the regulatory mechanism of hDPCs is important in inducing hair follicle(HF)regeneration in AA patients.Recently,growing evidence has indicated that 3 untranslated regions(3 UTR)of key genes may participate in the regulatory circuitry underlying cell differentiation and diseases through a socalled competing endogenous mechanism,but none have been reported in HF regeneration.Here,we demonstrate that the 3 UTR of junctional adhesion molecule A(JAM-A)could act as an essential competing endogenous RNA to maintain hDPCs function and promote HF regeneration in AA.We showed that the 3 UTR of JAM-A shares many microRNA(miRNA)response elements,especially miR-221–3p,with versican(VCAN)mRNA,and JAM-A 3 UTR could directly modulate the miRNA-mediated suppression of VCAN in self-renewing hDPCs.Furthermore,upregulated VCAN can in turn promote the expression level of JAM-A.Overall,we propose that JAM-A 3 UTR forms a feedback loop with VCAN and miR-221–3p to regulate hDPC maintenance,proliferation,and differentiation,which may lead to developing new therapies for hair loss. | Minjuan Wu Chen Xu Junfeng Jiang Sha Xu Jun Xiong Xiaoming Fan Kaihong Ji Yunpeng Zhao Haitao Ni Yue Wang Houqi Liu Zhaofan Xia | 2022 | Precision Clinical Medicine2022，5，3： | 0 |
| 10 | Application of the Common Offset Seismic Reflection Method to Urban Active Fault Surveys显示文摘The method and principle of common offset seismic surveys as well as the field data gathering and processing technique were introduced briefly. Through two urban active fault survey examples in Fuzhou and Shenyang, the efficiency and limitation of using the common offset seismic reflection technique to carry out urban active fault surveys were probed. The results show that this technique has the properties of high resolving power, better reconstruction of subsurface structures, and real-time analyzing and interpretation of investigation results on site. This method can be used to quickly locate objects under investigation accurately in the areas with thinner Quaternary overburdens and strong bedrock interface fluctuations. | Liu Baojin Ji Jifa Xu Zhaofan Yuan Hongke Liao Xu Bai Yun Wan Bo | 2007 | Earthquake Research in China2007，21，2： | 0 |
| 11 | Earthquake Monitoring and Study in the Jingpohu Volcano Cluster Area显示文摘Seismicity in the Jingpohu volcanic area was investigated based on the seismic data recorded by the mobile seismic network consisting of 14 stations equipped with 24-bit broad-band 3-component seismographs around Crater Forest.Results show that there appears certain seismicity in Jingpohu and its adjacent areas with a low activity level and most of the recorded earthquakes are the volcanic-tectonic ones.The results of location indicate a dominant focal depth of 10km~30km,most of the earthquakes are smaller than M_L2.0,and are concentrated in the area of 'Crater Forest' and on the Dunhua-Mishan fault which runs through the volcanic area.At station No.2,which has better observation conditions,two types of events,likely associated to volcanism,were recorded;their waveform characteristics are somewhat similar to that of the long-period volcanic event and the volcanic tremor,but with different feature of frequencies. | Liu Zhi Duan Yonghong Xu Zhaofan Yuan Qinxi Yang Jian Zhou Xuesong | 2008 | Earthquake Research in China2008，22，2： | 0 |
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