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| 1 | Structure and microtribological characteristics of laser-arc deposited TiB_2 thin film显示文摘TiB2 thin film was deposited by laser-arc deposition method on the surface of single crystalline silicon. The morphology, composition, structure and microtribological properties of the film were studied by using XPS, XRD and atomic force/friction force microscope (AFM/FFM). The results show that TiB2 (100) preferred growth on the Si(100)substrate, TiB2(001) preferred growth on the Si(111) substrate. The TiB2 thin film was composed of TiB2 and a small amount of TiO2. The friction coefficient of TiB2 film on substrates Si (100) and Si(111) in microtribological process were 0.087 and 0.073,respectively. TiB2 thin film displayed distinct ability of anti-scratch and wear-resistance. | CAO Xiankun, SHAO Tianmin, WEN Shizhu, QING Tao & QI FengState Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China The College of Mechanical & Electronic Engineering, WHUT, Wuhan 430070, China | 2004 | Science China(Physics,Mechanics & Astronomy)2004，47，z1： | 3 |
| 2 | Flexible electronics and optoelectronics of 2D van der Waals materials显示文摘Flexible electronics and optoelectronics exhibit inevitable trends in next-generation intelligent industries,including healthcare and wellness,electronic skins,the automotive industry,and foldable or rollable displays.Traditional bulk-material-based flexible devices considerably rely on lattice-matched crystal structures and are usually plagued by unavoidable chemical disorders at the interface.Two-dimensional van der Waals materials(2D VdWMs)have exceptional multifunctional properties,including large specific area,dangling-bond-free interface,plane-to-plane van der Waals interactions,and excellent mechanical,electrical,and optical properties.Thus,2D VdWMs have considerable application potential in functional intelligent flexible devices.To utilize the unique properties of 2D VdWMs and their van der Waals heterostructures,new designs and configurations of electronics and optoelectronics have emerged.However,these new designs and configurations do not consider lattice mismatch and process incompatibility issues.In this review,we summarized the recently reported 2D VdWM-based flexible electronic and optoelectronic devices with various functions thoroughly.Moreover,we identified the challenges and opportunities for further applications of 2D VdWM-based flexible electronics and optoelectronics. | Huihui Yu Zhihong Cao Zheng Zhang Xiankun Zhang Yue Zhang | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，4： | 2 |
| 3 | Inhibition of furin by bone targeting superparamagnetic iron oxide nanoparticles alleviated breast cancer bone metastasis显示文摘Breast cancer bone metastasis poses significant challenge for therapeutic strategies.Inside the metastatic environment,osteoclasts and tumor cells interact synergistically to promote cancer progression.In this study,the proprotein convertase furin is targeted due to its critical roles in both tumor cell invasion and osteoclast function.Importantly,the furin inhibitor is specifically delivered by bone targeting superparamagnetic iron oxide(SPIO)nanoparticles.Our in vitro and in vivo data demonstrate that this system can effectively inhibit both osteoclastic bone resorption and breast cancer invastion,leading to alleviated osteolysis.Therefore,the bone targeting&furin inhibition nanoparticle system is a promising therapeutic and diagnostic strategy for breast cancer bone metastasis. | Yichuan Pang Li Su Yao Fu Fan Jia Chenxi Zhang Xiankun Cao Wenxin He Xueqian Kong Jiake Xu Jie Zhao An Qin | 2021 | Bioactive Materials2021，6，3： | 2 |
| 4 | Universal transfer of full-class metal electrodes for barrier-free two-dimensional semiconductor contacts显示文摘Metal–semiconductor contacts are crucial components in semiconductor devices.Ultrathin two-dimensional transition-metal dichalcogenide semiconductors can sustain transistor scaling for next-generation integrated circuits.However,their performance is often degraded by conventional metal deposition,which results in a high barrier due to chemical disorder and Fermi-level pinning(FLP).Although,transferring electrodes can address these issues,they are limited in achieving universal transfer of full-class metals due to strong adhesion between pre-deposited metals and substrates.Here,we propose a nanobelt-assisted transfer strategy that can avoid the adhesion limitation and enables the universal transfer of over 20 different types of electrodes.Our contacts obey the Schottky–Mott rule and exhibit a FLP of S=0.99.Both the electron and hole contacts show record-low Schottky barriers of 4.2 and 11.2 meV,respectively.As a demonstration,we construct a doping-free WSe2 inverter with these high-performance contacts,which exhibits a static power consumption of only 58 pW.This strategy provides a universal method of electrode preparation for building high-performance post-Moore electronic devices. | Mengyu Hong Xiankun Zhang Yu Geng Yunan Wang Xiaofu Wei Li Gao Huihui Yu Zhihong Cao Zheng Zhang Yue Zhang | 2024 | InfoMat2024，6，1： | 0 |
| 5 | Cloning and Characterization of DULP,a Novel Ubiquitin-Like Molecule from Human Dendritic Cells显示文摘We identified a novel ubiquitin-like molecule DULP from human dendritic cells. DULP contains a domain that shares 26% identity and 34% similarity with ubiquitin,and it possesses the corresponding Ile-44 hydrophobic patch used by mono-or poly-ubiquitin to interact with a ubiquitin-interaction motif(UIM) or ubiquitin-associated domain(UBA) . Lysine residue corresponding to 6 of ubiquitin,which is involved in the formation of a multi-ubiquitin chain that can bind proteasomal subunit Rpn10/S5a,is also conserved in its ubiquitin-homology domain. However,DULP does not possess the highly conserved C-terminus Gly-Gly required for ubiquitin conjugation or the Lys-48 required for the formation of polyubiquitin chain to target substrates for degradation,suggesting it might be a novel ubiquitin-domain protein(UDP) . DULP was found widely expressed in many cells and the ubiquitin-homology domain was not cleaved. We also confirmed that DULP expression was enriched in the nucleus and much weaker in the cytosol. Besides,we found that overexpression of DULP in 293T cells induced apoptosis,which might not be associated with the mitochondrial or proteasome pathway,with the specific mechanism remain unclear. Further investigations are needed to identify the precise biological functions of DULP. | Guoyan Liu Shuxun Liu Ping Li Ling Tang Yanmei Han Huazhang An Jiangyan Li Xiankun Dai Nan Li Xuetao Cao Yizhi Yu | 2009 | Cellular & Molecular Immunology2009，6，1： | 0 |
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