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您的检索式：作者名="Xianliang Gu"
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| 1 | Measurements of atmospheric nitrous acid and nitric acid显示文摘 | Huang Gu Zhou Xianliang Deng Guohong | 2002 | AtmosphericEnvironment2002，36，： | 1 |
| 2 | China is initiating the Aquatic 10-100-1,000 Genomics Program显示文摘On June 17 of 2016,a group of scientists from Chinese Academy of Fishery Sciences(CAFS)and Shenzhen BGI Fisheries Sci&Tech Co.Ltd.(BGI Fisheries)met together in Shenzhen,China to launch a novel project,the China Aquatic 10-100-1,000 Genomics Program,to conduct molecular breeding of^10 aquaculture species and sequence genomes of^100 and transcriptomes of^1,000 aquatic species.The main objective of this project is to build | Yingjie Liu Pao Xu Junmin Xu Yu Huang Yongxin Liu Hui Fang Yinchang Hu Xinxin You Chao Bian Min Sun Ruobo Gu Lifeng Cui Xianliang Zhang Peng Xu Qiong Shi | 2017 | Science China(Life Sciences)2017，60，3： | 0 |
| 3 | Toxicity of silicon dioxide nanoparticles with varying sizes on the cornea and protein corona as a strategy for therapy显示文摘The human cornea is exposed directly to particulate matter(PM) in polluted air. This exposure can cause eye discomfort and corneal injury. Ultrafine PM(diameter <100 nm) is thought to be particularly harmful to health, but there is limited research investigating its toxicity to the eye. In this study, we evaluated toxicity differences among 30-, 40-, 100-and 150-nm silicon dioxide nanoparticles(SiO_2 NPs) on the cornea. A 24-hour in vitro exposure of primary human corneal epithelial cells(hCECs) to ultrafine(30 and 40 nm) SiO_2 NPs produced toxicity, as evidenced by cell membrane damage, reduced cell viability,increased cell death and mitochondrial dysfunction. In vivo exposure to the same nanoparticles produced observable corneal injury. These effects were more severe with ultrafine than with fine(100 and 150 nm)SiO_2 NPs. Common antioxidant compounds, e.g., glutathione, did not protect the cornea from SiO_2 NP-induced damage. However, foetal bovine serum(FBS) did significantly reduce toxicity, likely by forming a protective protein corona around the nanoparticles. This finding suggests that FBS(or its derivatives) may be a useful clinical therapy for corneal toxicity caused by ultrafine particulates. | Dayu Sun Linji Gong Jing xie Xianliang Gu Yijian Li Qinglin Cao Qiyou Li Luodan A. Zhanjun Gu Haiwei Xu | 2018 | Science Bulletin2018，63，14： | 0 |
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