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您的检索式：作者名="Xinbao Sun"
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| 1 | CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance显示文摘 | Gaopeng Li Xiaoli Wu Wenchang Qian Huayong Cai Xinbao Sun Weijie Zhang Sheng Tan Zhengsheng Wu Pengxu Qian Keshuo Ding Xuefei Lu Xiao Zhang Hong Yan Haifeng Song Shouhong Guang Qingfa Wu Peter E Lobie Ge Shan Tao Zhu | 2016 | Cell Research2016，26，6： | 3 |
| 2 | Degradation particles derived from high-purity magnesium inhibit osteogenic differentiation through regulation of macrophage polarization显示文摘Magnesium(Mg)and its alloys have great potential as orthopedic implant candidates,which could release various bioactive substances during degradation.Degradation particles(DPs)are one of the degradation products,but the osteoimmunology effects are still unclear.In this study,the effect of DPs on the polar-ization of macrophages and their release of cytokines was investigated.The results verify that excessive generation of DPs from biodegradable Mg can induce macrophages to realize polarization of proinflamma-tory M1 phenotype.Moreover,macrophages secrete proinflammatory cytokines to inhibit the osteogenic differentiation of rat bone marrow stem cells(rBMSCs).This suggests that the effects of DPs should be considered when evaluating Mg-based implants.DPs continuously produced with the degradation of Mg-based implants may influence osseointegration. | Yu Sun Han Yu Hongzhou Peng Xinbao Kang Zhaoxiang Peng Xieping Dong Wenhui Wang Yang Song Xiaonong Zhang | 2023 | Journal of Materials Science & Technology2023，，8： | 1 |
| 3 | Complexity and characteristic frequency studies in ECG signals of mice based on multiple scale factors显示文摘Existing methods of physiological signal analysis based on nonlinear dynamic theories only examine the complexity difference of the signals under a single sampling frequency.We developed a technique to measure the multifractal characteristic parameter intimately associated with physiological activities through a frequency scale factor.This parameter is highly sensitive to physiological and pathological status.Mice received various drugs to imitate different physiological and pathological conditions,and the distributions of mass exponent spectrum curvature with scale factors from the electrocardiogram (ECG) signals of healthy and drug injected mice were determined.Next,we determined the characteristic frequency scope in which the signal was of the highest complexity and most sensitive to impaired cardiac function,and examined the relationships between heart rate,heartbeat dynamic complexity,and sensitive frequency scope of the ECG signal.We found that all animals exhibited a scale factor range in which the absolute magnitudes of ECG mass exponent spectrum curvature achieve the maximum,and this range (or frequency scope) is not changed with calculated data points or maximal coarse-grained scale factor.Further,the heart rate of mice was not necessarily associated with the nonlinear complexity of cardiac dynamics,but closely related to the most sensitive ECG frequency scope determined by characterization of this complex dynamic features for certain heartbeat conditions.Finally,we found that the health status of the hearts of mice was directly related to the heartbeat dynamic complexity,both of which were positively correlated within the scale factor around the extremum region of the multifractal parameter.With increasing heart rate,the sensitive frequency scope increased to a relatively high location.In conclusion,these data provide important theoretical and practical data for the early diagnosis of cardiac disorders. | YANG XiaoDong HE AiJun LIU Peng SUN TongFeng NING XinBao | 2011 | Science China(Life Sciences)2011，54，6： | 1 |
| 4 | Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity显示文摘 | Jia Li Caroline Romestaing Xianlin Han Yuan Li Xinbao Hao Yinyuan Wu Chao Sun Xiaolei Liu Leonard S. Jefferson Jingwei Xiong Kathryn F. LaNoue Zhijie Chang Christopher J. Lynch Huayan Wang Yuguang Shi | 2010 | Cell Metabolism2010，，2： | 1 |
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