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| 1 | Increased leptin by hypoxic-preconditioning promotes autophagy of mesenchymal stem cells and protects them from apoptosis显示文摘Autophagy is the basic catabolic progress involved in cell degradation of unnecessary or dysfunctional cellular components.It has been proven that autophagy could be utilized for cell survival under stresses.Hypoxic-preconditioning(HPC)could reduce apoptosis induced by ischemia and hypoxia/serum deprivation(H/SD)in bone marrow-derived mesenchymal stem cells(BMSCs).Previous studies have shown that both leptin signaling and autophagy activation were involved in the protection against apoptosis induced by various stress,including ischemia-reperfusion.However,it has never been fully understood how leptin was involved in the protective effects conferred by autophagy.In the present study,we demonstrated that HPC can induce autophagy in BMSCs by increased LC3-II/LC3-I ratio and autophagosome formation.Interestingly,similar effects were also observed when BMSCs were pretreated with rapamycin.The beneficial effects offered by HPC were absent when BMSCs were incubated with autophagy inhibitor,3-methyladenine(3-MA).In addition,down-regulated leptin expression by leptin-shRNA also attenuated HPC-induced autophagy in BMSCs,which in turn was associated with increased apoptosis after exposed to sustained H/SD.Furthermore,increased AMP-activated protein kinase phosphorylation and decreased mammalian target of rapamycin phosphorylation that were observed in HPC-treated BMSCs can also be attenuated by down-regulation of leptin expression.Our data suggests that leptin has impact on HPC-induced autophagy in BMSCs which confers protection against apoptosis under H/SD,possibly through modulating both AMPK and mTOR pathway. | WANG LiHan HU XinYang ZHU Wei JIANG Zhi ZHOU Yu CHEN PanPan WANG JianAn | 2014 | Science China(Life Sciences)2014,57,2: | 8 |
| 2 | SOLUTION OF A CLASS OF INVESTMENT DEVELOPMENTAL EQUATIONS显示文摘The paper discusses the solution of a class of assets developmental equations. We get the existence and uniqueness of global solution, and under the constancy of state obtain the stability of solution. | JIAO Hongbing (Department of Mathematics, Hebei Teacher’s University, Shijiazhuang 050016, China) YU Jingyuan (Beijing Institute of Information and Control, Beijing 100037, China) QI Chuanda (Henan Xinyang Teacher’s College, Xinyany 464000, China) | 2000 | Systems Science and Mathematical Sciences2000,13,2: | 4 |
| 3 | Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats显示文摘 | Ling Wei Jamie L. Fraser Zhong-Yang Lu Xinyang Hu Shan Ping Yu | 2012 | Neurobiology of Disease2012,,3: | 3 |
| 4 | Synthesis and Characterization of Chiral Organogallium and Indium Complexes with Salen Ligands显示文摘Several new chiral organogallium and indium complexes with chiral Salen (1 and 2) as anxciliary ligands have been synthesized and characterized by elemental analysis, IR, 1H NMR and Mass spectroscopy. For the gallium, mono and bimetallic complexes were obtained, whereas ring closure complexes of indium were obtained. | Fu Xing GAO1,2, Cheng Jian ZHU1*, Fang YUAN1, Yu Hua ZHU1, Yi PAN1* 1Department of Chemistry, Nanjing University, Nanjing 210093 2Department of Chemistry, Xinyang Normal College, Xinyang 464000 | 2003 | Chinese Chemical Letters2003,14,2: | 3 |
| 5 | Flotation performance of a novel Gemini collector for kaolinite at low temperature显示文摘How to sustainably produce bauxite by effective reverse froth flotation of kaolinite at low temperature is an urgent problem to be solved in the field of mineral processing.In this work,a novel amino-based Gemini surfactant butadiyl-1,4-bis(dimethyl dodecylammonium bromide)(BBDB) was prepared and first utilized as a novel collector for kaolinite flotation.Its flotation performance for kaolinite was compared with that of the common monomolecular surfactant 1-dodecylamine(DDA) by micro-flotation tests.The tests results indicated that 95% kaolinite recovery was obtained using 2.0×10^(-4) mol/L BBDB at 25℃ which was half of the dosage when DDA obtained the maximum kaolinite recovery of81%.At extremely low temperature(0℃),3.0×10^(-4) mol/L BBDB could still collect 91% kaolinite,while DDA showed a frustrating ability.The contact angle tests indicated that BBDB could still significantly improve the hydrophobicity of the kaolinite surface(contact angle 71.7°) than DDA(contact angle only25.8°) at 0℃.The Krafft point comparison tests indicated that BBDB had a much lower Krafft point(below0℃) than DDA.Fourier transform infrared spectroscopy(FTIR)-spectrum analysis and zeta potential measurements showed that BBDB was physically adsorbed on the surface of kaolinite through electrostatic interaction. | Shiyong Zhang Zhiqiang Huang Hongling Wang Rukuan Liu Chen Cheng Shuyi Shuai Yajing Hu Zhiqun Guo Xinyang Yu Guichun He Weng Fu | 2021 | International Journal of Mining Science and Technology2021,31,6: | 2 |
| 6 | Multi-objective microgrid optimal dispatching based on improved bird swarm algorithm显示文摘Multi-objective optimal dispatching schemes with intelligent algorithms are recognized as effective measures to promote the economics and environmental friendliness of microgrid applications.However,the low accuracy and poor convergence of these algorithms have been challenging for system operators.The bird swarm algorithm(BSA),a new bio-heuristic cluster intelligent algorithm,can potentially address these challenges;however,its computational iterative process may fall into a local optimum and result in premature convergence when optimizing small portions of multi-extremum functions.To analyze the impact of a multi-objective economic-environmental dispatching of a microgrid and overcome the aforementioned problems of the BSA,a self-adaptive levy flight strategy-based BSA(LF-BSA)was proposed.It can solve the dispatching problems of microgrid and enhance its dispatching convergence accuracy,stability,and speed,thereby improving its optimization performance.Six typical test functions were used to compare the LF-BSA with three commonly accepted algorithms to verify its excellence.Finally,a typical summer-time daily microgrid scenario under grid-connected operational conditions was simulated.The results proved the feasibility of the proposed LF-BSA,effectiveness of the multi-objective optimization,and necessity of using renewable energy and energy storage in microgrid dispatching optimization. | Xiaoyan Ma Yunfei Mu Yu Zhang Chenxi Zang Shurong Li Xinyang Jiang Meng Cui | 2022 | Global Energy Interconnection2022,5,2: | 2 |
| 7 | Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis显示文摘 | HU Xinyang YU Shanping FRASER J L | 2008 | J Thorac Cardiovasc Surg2008,135,4: | 1 |
| 8 | INTEGRABLE COUPLINGS OF THE TB HIERARCHY AND ITS HAMILTONIAN STRUCTURE显示文摘In this paper,we obtain integrable couplings of the TB hierarchy using the new subalgebra of the loop algebra A_3.Then the Hamiltonian structure of the above system is given by the quadratic-form identity. | Zhang Yu Dong Huanhe (College of Information Science and Engineering,Shandong University of Science and Technology,Qingdao 266510,Shandong) Li Zhu (College of Math.and Inform.Science,Xinyang Normal University,Xinyang 464000,Henan) | 2008 | Annals of Differential Equations2008,24,1: | 1 |
| 9 | Flotation separation of diaspore from kaolinite, pyrophyllite and illite using three cationic collectors显示文摘 | Hong Zhong Guangyi Liu Liuyin Xia Yiping Lu Yuehua Hu Shenggui Zhao Xinyang Yu | 2008 | Minerals Engineering2008,,: | 1 |
| 10 | The synthesis of novel organosilicon collector qAS222 and its flotation performance on aluminosilicate minerals显示文摘 | Yu Xinyang Xia Liuyin Wang Shuai | | 0,,: | 1 |
| 11 | Reverse flotation of diaspore from aluminosilicates by a new cationic organosilicon,quaternry ammonium collector显示文摘 | Yu Xinyang Zhong Hong Liu Guangyi | | 0,,3: | 1 |
| 12 | Quasi-Solid-State Ion-Conducting Arrays Composite Electrolytes with Fast Ion Transport Vertical-Aligned Interfaces for All-Weather Practical Lithium-Metal Batteries显示文摘The rapid improvement in the gel polymer electrolytes(GPEs)with high ionic conductivity brought it closer to practical applications in solid-state Li-metal batteries.The combination of solvent and polymer enables quasi-liquid fast ion transport in the GPEs.However,different ion transport capacity between solvent and polymer will cause local nonuniform Li+distribution,leading to severe dendrite growth.In addition,the poor thermal stability of the solvent also limits the operating-temperature window of the electrolytes.Optimizing the ion transport environment and enhancing the thermal stability are two major challenges that hinder the application of GPEs.Here,a strategy by introducing ion-conducting arrays(ICA)is created by vertical-aligned montmorillonite into GPE.Rapid ion transport on the ICA was demonstrated by 6Li solid-state nuclear magnetic resonance and synchrotron X-ray diffraction,combined with computer simulations to visualize the transport process.Compared with conventional randomly dispersed fillers,ICA provides continuous interfaces to regulate the ion transport environment and enhances the tolerance of GPEs to extreme temperatures.Therefore,GPE/ICA exhibits high room-temperature ionic conductivity(1.08 mS cm^(−1))and long-term stable Li deposition/stripping cycles(>1000 h).As a final proof,Li||GPE/ICA||LiFePO_(4) cells exhibit excellent cycle performance at wide temperature range(from 0 to 60°C),which shows a promising path toward all-weather practical solid-state batteries. | Xinyang Li Yong Wang Kai Xi Wei Yu Jie Feng Guoxin Gao Hu Wu Qiu Jiang Amr Abdelkader Weibo Hua Guiming Zhong Shujiang Ding | 2022 | Nano-Micro Letters2022,14,12: | 1 |
| 13 | Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis显示文摘 | Hu Xinyang Yu Shanping Fraser J L | | 0,,04: | 1 |
| 14 | Flexible, self-cleaning, and high-performance ceramic nanofiber-based moist-electric generator enabled by interfacial engineering显示文摘Due to their long-term stability, even under extreme conditions, oxide ceramics have attracted significant attention in emerging fields like moist-electric generation. However, the inherent brittleness and low voltage output of oxide ceramic-based moistelectric generators(MEGs) limit their applications in wearable electronics. Herein, a facile strategy involving the combination of sol-gel electrospinning and calcination is used to fabricate flexible and freestanding Ti O_(2)/Zr O_(2)(TZ) composite nanofiber-based MEGs. The excellent flexibility of the TZ nanofiber membranes can be attributed to the suppression of their crystal structure transformation, dispersion of stress concentration, and reduction of crack propagation via interfacial engineering. The porous structure of the electrospun nanofiber membrane features an abundance of charged narrow channels for the diffusion of water molecules and generates a streaming potential. The optimal voltage output reached ~0.8 V, which is the highest value reported for an oxide ceramic-based MEG. Furthermore, the as-fabricated nanofiber-based MEG exhibits good self-cleaning capability to degrade organic pollutants under ultraviolet irradiation. By integrating mechanical flexibility, high performance, and a selfcleaning effect, this work presents a new idea for exploring diverse, efficient, and wearable oxide ceramic-based MEGs. | WANG LiMing FENG LanLan SUN Zhao Yang HE XinYang WANG RongWu QIN XiaoHong YU JianYong | 2022 | Science China(Technological Sciences)2022,65,2: | 1 |
| 15 | Preparation of cinnamic hydroxamic acid collector and study on flotation characteristics and mechanism of scheelite显示文摘In this paper,using methyl cinnamate as raw material,the new cinnamic hydroxamic acid collector(CIHA)was synthesized by the hydroxylamine method.The collector performance of hydroxamic acid was investigated for scheelite and gangue calcite,and the flotation separation test of scheelite and calcite was carried out with CIHA as the collector.The interaction mechanism between hydroxamic acid and scheelite minerals has also been investigated through zeta potential,Fourier transform infrared spectroscopy(FTIR)experiments,X-ray photoelectron spectroscopy(XPS)experiments,and density functional theory(DFT)calculation.The single mineral flotation test and artificially mixed ore showed that CIHA had an excellent collection effect and selectivity.Zeta potential,FTIR,and XPS showed that CIHA was adsorbed on the scheelite surface by strong chemical adsorption.The active group of CIHA was analyzed through quantum chemical calculation.It was speculated that C=O and N-O bonds could synthesize a five-membered chelated hydroxamic acid group with Ca element chelate on scheelite surface,changing hydrophobicity and making it more likely to emerge from the pulp. | Xiang Yao Xinyang Yu Liping Wang Yuhui Zeng Linghan Mao Shanming Liu Honghui Xie Guichun He Zhiqiang Huang Zhilin Liu | 2023 | International Journal of Mining Science and Technology2023,33,6: | 1 |
| 16 | In-situ polymerized carbonate induced by Li-Ga alloy as novel artificial interphase on Li metal anode显示文摘Li metal is considered an ideal anode material because of its high theoretical capacity and low electrode potential.However,the practical usage of Li metal as an anode is severely limited because of inevitable parasitic side reactions with electrolyte and dendrites formation.At present,single-component artificial solid electrolyte interphase cannot simultaneously meet the multiple functions of promoting ion conduction,guiding lithium ion deposition,inhibiting dendrite growth,and reducing interface side reactions.Therefore,multi-component design on Li metal surface is widely investigated to achieve long-term cycling.Herein,we report a Li_(2)Ga-carbonate polymer interphase layer to solve volume changes,Li dendrites formation and side-reactions.As a result,the Li symmetric cell can be stabilized at 3.0 m A/cm^(2)in carbonate electrolyte with limited volume of 20μL.Coupled with 13.6 mg/cm^(2)(loading of 2 mAh/cm^(2))LiFePO_(4)cathode,discharge capacity retains at 90%for over 150 cycles under limited electrolyte conditions.With such an alloy-polymer interphase layer,higher energy density Li metal batteries become prominent in the near future. | Ziping Wang Shuyuan Xie Xuejie Gao Xinyang Chen Lina Cong Jun Liu Haiming Xie Chuang Yu Yulong Liu | 2023 | Chinese Chemical Letters2023,34,9: | 0 |
| 17 | Highly stretchable,durable,and breathable thermoelectric fabrics for human body energy harvesting and sensing显示文摘Stretchable thermoelectrics have recently attracted widespread attention in the field of self-powered wearable electronics due to their unique capability of harvesting body heat.However,it remains challenging to develop thermoelectric materials with excellent stretchability,durable thermoelectric properties,wearable comfort,and multifunctional sensing properties simultaneously.Herein,an advanced preparation strategy combining electrospinning and spraying technology is proposed to prepare carbon nanotube(CNT)/polyvinyl pyrrolidone(PVP)/polyurethane(PU)composite thermoelectric fabrics that have high air permeability and stretchability(~250%)close to those of pure PU nanofiber fabrics.Furthermore,PVP can not only improve the dispersion of CNTs but also act as interfacial binders between the CNT and the elastic PU skeleton.Consequently,both the electrical conductivity and the Seebeck coefficient remain unchanged even after bending 1000 times.In addition,self-powered sensors for the mutual conversion of finger temperature and language and detection of the movement of joints to optimize an athlete's movement state were successfully fabricated.This study paves the way for stretchable thermoelectric fabrics with fascinating applications in smart wearable fields such as power generation,health monitoring,and human–computer interaction. | Xinyang He Jia Shi Yunna Hao Mantang He Jiaxin Cai Xiaohong Qin Liming Wang Jianyong Yu | 2022 | Carbon Energy2022,4,4: | 0 |
| 18 | Visualization of α_1-adrenergic receptors with phenylpiperazine-based fluorescent probes显示文摘Several novel fluorescent probes targeting α_1-adrenergic receptors were well designed and synthesized by conjugating phenylpiperazine pharmacophore with coumarin and fluorescein fluorophores. These compounds showed suitable fluorescence property, high receptor affinity, and low cytotoxicity. Moreover, the cell imaging results displayed that these probes can be effective tools for the real-time detection of ligand-receptor interactions, as well as the visualization and location of α_1-adrenergic receptors in living cells. | Yuxing Lin Wenhua Li Qinying Yu Xinyang Zhou Wei Zhang Lupei Du Minyong Li | 2016 | Science China Chemistry2016,59,5: | 0 |
| 19 | Air target intention recognition and causal effect analysis combining uncertainty information reasoning and potential outcome framework显示文摘Recognizing target intent is crucial for making decisions on the battlefield.However,the imperfect and ambiguous character of battlefield situations challenges the validity and causation analysis of classical intent recognition techniques.Facing with the challenge,a target intention causal analysis paradigm is proposed by combining with an Intervention Retrieval(IR)model and a Hybrid Intention Recognition(HIR)model.The target data acquired by the sensors are modelled as Basic Probability Assignments(BPAs)based on evidence theory to create uncertain datasets.Then,the HIR model is utilized to recognize intent for a tested sample from uncertain datasets.Finally,the intervention operator under the evidence structure is utilized to perform attribute intervention on the tested sample.Data retrieval is performed in the sample database based on the IR model to generate the intention distribution of the pseudo-intervention samples to analyze the causal effects of individual sample attributes.The simulation results demonstrate that our framework successfully identifies the target intention under the evidence structure and goes further to analyze the causal impact of sample attributes on the target intention. | Yu ZHANG Fanghui HUANG Xinyang DENG Mingda LI Wen JIANG | 2024 | Chinese Journal of Aeronautics2024,37,1: | 0 |
| 20 | Dendrimers-merging biomimics and photoenergy conversion显示文摘Dendrimers are well-defined tree-like macromolecules possessing numerous chain ends emanating from a single core, which makes them attractive candidates for mimicking light-harvesting systems and hydrogenases. Photoinduced electron and energy transfers are main processes involved in light-harvesting and photocatalysis. In this review, the general concepts of design strategies and recent developments of photofunctional dendrimers in biomimics of light-harvesting systems and hydrogenases are discussed. The energy transfer and electron transfer processes in light-harvesting dendrimers and the effect of dendritic structures in photochemical hydrogen production are illustrated. | Xinyang Liu Yi Zeng Xiaohui Zhang Tianjun Yu Jinping Chen Yi Li | 2015 | Science China Chemistry2015,58,3: | 0 |