|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of bacterial and genetic factors in gastric cancer in Costa Rica显示文摘AIM: To evaluate several risk factors for gastric cancer (GC) in Costa Rican regions with contrasting GC incidence rate (GCIR). METHODS: According to GCIR, 191 Helicobacter pylori (H pylori)-positive patients were classified into groups A (high GCIR, n = 101) and B (low GCIR, n = 90). Human DNA obtained from biopsy specimens was used in the determination of polymorphisms of the genes coding for interleukin (IL)-1β and IL-10 by PCR-RFLP, and IL-1RN by PCR. H pylori DNA extractions obtained from clinical isolates of 83 patients were used for PCR-based genotyping of H pylori cagA, vacA and babA2. Human DNA from gastric biopsies of 52 GC patients was utilized for comparative purposes. RESULTS: Cytokine polymorphisms showed no association with GCIR variability. However, gastric atrophy, intestinal metaplasia and strains with different vacA genotypes in the same stomach (mixed strain infection) were more frequently found in group A than in group B, and cagA and vacA s1b were signif icantly associated with high GCIR (P = 0.026 and 0.041, respectively). IL- 1β+3954_T/C (OR 2.1, 1.0-4.3), IL-1RN*2/L (OR 3.5, 1.7-7.3) and IL-10-592_C/A (OR 3.2, 1.5-6.8) were individually associated with GC, and a combination of these cytokine polymorphisms with H pylori vacA s1b and m1 further increased the risk (OR 7.2, 1.4-36.4). CONCLUSION: Although a proinflammatory cytokine genetic profile showed an increased risk for developing GC, the characteristics of H pylori infection, in particular the status of cagA and vacA genotype distribution seemed to play a major role in GCIR variability in Costa Rica. | Sergio A Con Hiroaki Takeuchi Gil R Con-Chin Vicky G Con-Chin Nobufumi Yasuda Reinaldo Con-Wong | 2009 | World Journal of Gastroenterology2009，15，2： | 9 |
| 2 | Platelet transfusion refractoriness associated with plasma proteins显示文摘 | OHTO H YASUDA H ABE R | 1993 | Br J Haematol1993，83，： | 1 |
| 3 | Global optimization method using chaos in dissipative system显示文摘 | FUJITA T YASUDA K YOKOYAMA R | 1995 | Electronics and Communications in Japan Part 3: Fundamental Electronic Science1995，78，1： | 1 |
| 4 | Effects of low-intensity bench press training with restricted arm muscle blood flow on chest muscle hypertrophy: a pilot study显示文摘 | YASUDA T FUJITA S OGASAWARA R | 2010 | Clin Physiol Funct Imaging2010，30，5： | 1 |
| 5 | Long term treatment with eicosapentaenoic acid ameliorates myocardial ischemia reperfusion injury in pigs in vivo显示文摘 | Gao J Y Yasuda S Tsuburaya R | 2011 | Circulation Journal2011，75，18： | 1 |
| 6 | Characterization of NMDA receptor subunit-specific antibodies: Distribution of NR2A and NR2B receptor subunits in rat brain and ontogenic profile in the cerebellum 显示文摘 | Wang Y Bosy T Z Yasuda R P | 1995 | J Neurochem1995，65，1： | 1 |
| 7 | Effects f blood flow restricted low-intensity concentric or eccentric training on muscle size and strength显示文摘 | YASUDA T LOENNEKE J P THIEBAUD R S | 2012 | PLoS One2012，7，12： | 1 |
| 8 | Clinical efficacy of sitafloxacin 100 mg twice daily for 7 days for patients with nongonococcal urethritis显示文摘 | Takahashi S Hamasuna R Yasuda M | 2013 | J Infect Chemother2013，19，5： | 1 |
| 9 | Metaplasticity at single glutamatergie synapses显示文摘 | Lee MC Yasuda R Ehlers biD | 2010 | Neuron2010，66，6： | 1 |
| 10 | Com- bined effects of low-intensity blood flow restriction training and high-intensity resistance training on muscle strength and size 显示文摘 | YASUDA T OGASAWARA R SAKAMAKI M | 2011 | Eur J Appl Physiol2011，111，10： | 1 |
| 11 | Direct observation of the rota- tion of F1-ATPase显示文摘 | NOJI H YASUDA R YOSHIDA M | 1997 | Nature1997，386，20： | 1 |
| 12 | Progression of joint arth- rosis 10 to 15 years after high tibial osteotomy显示文摘 | Majima T Yasuda K Katsuragi R | 2000 | Clin Orthop Relat Res2000，，381： | 1 |
| 13 | Study on ISL network structure in LEO satellite communication systems显示文摘 | SUZUKI R YASUDA Y | 2007 | Acta Astronautica2007，61，： | 1 |
| 14 | Shear flow properties of concentrated solutions of linear and star branched polystyrenes 显示文摘 | YASUDA K ARMSTRONG R COHEN R | 1981 | Rheologica Acta1981，20，2： | 1 |
| 15 | Expression of interleukin-6,interleukin-6 receptor (gp80),and the receptor's signal-transducing subunit (gp130) in human normal pituitary glands and pituitary adenomas显示文摘 | Kurotani R Yasuda M Oyama K | 2001 | Mod Pathol2001，14，8： | 1 |
| 16 | Characterizing preferential transport during flood irrigation of a heavy clay soil using the dye Vitasyn Blau显示文摘 | Yasuda H Berndtsson R Persson H | 2001 | Geoderma2001，100，： | 1 |
| 17 | The effect of non-physio- logically high initial tension on the mechanical properties of in situ frozen anterior cruciate ligament in a canine model显示文摘 | Katsuragi R Yasuda K Tsujino J | 2000 | Am J Sports Med2000，28，1： | 1 |
| 18 | Cyclin B1 mRNA transla- tion is temporally controlled through formation and disas- sembly of RNA granules显示文摘 | Kntani T Yasuda K Ota R | 2013 | J Cell Biol2013，202，7： | 1 |
| 19 | Evolution of the pregnane x receptor:adaptation to cross-species differences in biliary bile salts显示文摘 | KRASOWSKI M D YASUDA K HAGEY L R | 2005 | Mol Endocrinol2005，19，7： | 1 |
| 20 | Synthesis of 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl (BINAP),an atropisomeric chiral bis(triaryl)phosphine,and its use in the rhodium(Ⅰ)-catalyzed asymmetric hydrogenation of α-(acylamino)acrylic acids显示文摘 | Miyashita M Yasuda A Noyori R | 1980 | J Am Chem Soc1980，102，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员