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| 1 | Inflammatory bowel disease and cancer: The role of inflammation, immunosuppression, and cancer treatment显示文摘In patients with inflammatory bowel disease(IBD), chronic inflammation is a major risk factor for the development of gastrointestinal malignancies. The pathogenesis of colitis-associated cancer is distinct from sporadic colorectal carcinoma and the critical molecular mechanisms underlying this process have yet to be elucidated. Patients with IBD have also been shown to be at increased risk of developing extra-intestinal malignancies. Medical therapies that diminish the mucosal inflammatory response represent the foundation of treatment in IBD, and recent evidence supports their introduction earlier in the disease course. However, therapies that alter the immune system, often used for long durations, may also promote carcinogenesis. As the population of patients with IBD grows older, with longer duration of chronic inflammation and longer exposure to immunosuppression, there is an increasing risk of cancer development. Many of these patients will require cancer treatment, including chemotherapy, radiation, hormonal therapy, and surgery. Many patients will require further treatment for their IBD. This review seeks to explore the characteristics and risks of cancer in patients with IBD, and to evaluate the limited data on patients with IBD and cancer, including management of IBD after a diagnosis of cancer, the effects of cancer treatment on IBD, and the effect of IBD and medications for IBD on cancer outcomes. | Jordan E Axelrad Simon Lichtiger Vijay Yajnik | 2016 | World Journal of Gastroenterology2016，22，20： | 33 |
| 2 | Early life origins of insulin resistance and type 2 diabetes in India and other Asian countries显示文摘 | Yajnik CS | 2004 | J Nutr2004，134，1： | 1 |
| 3 | Conventional and novel cardiovascular risk factors and markers of vascular damage in rural and urban Indian men显示文摘 | Chittaranjan S. Yajnik Charudatta V. Joglekar Manoj C. Chinchwadkar Mehmood G. Sayyad Swapna S. Deshpande Sadanand S. Naik Dattatray S. Bhat Anjali Ganpule Prakash Shetty John S. Yudkin | 2011 | International Journal of Cardiology2011，，： | 1 |
| 4 | The spectrum of pancreatic exoerine and endocrine (beta-cell) function in tropical caleifie pancreatitis 显示文摘 | Yajnik CS Shelgikar KM Sabasrabudhe RA | 1990 | Diabetologia1990，33，7： | 1 |
| 5 | Artificial neural network as an alternative to multiple regression analysis in optimizing formulation parameters of cytarabine liposomes显示文摘 | Subramanian N Yajnik A Murthy RS | 2004 | AAPS Pharm-SciTech2004，5，1： | 1 |
| 6 | Hedgehog is an early and late mediator of pancreatic cancer tumorigene- sis 显示文摘 | Thayer SP Yajnik V Antoniu B | 2003 | Nature2003，425，6960： | 1 |
| 7 | Case report:cystitis glandularis mimics bladder tumour:a case report and diagnostic characteristics显示文摘 | Lee G Tsiriopoulos I Yajnik K | | 0，，04： | 1 |
| 8 | 显示文摘 | Yajnik CS | 1995 | Diabet Med1995，12，： | 1 |
| 9 | Maternal nutrition, intrauterine programming and consequential risks in the offspring显示文摘 | Yajnik CS Deshmukh US | 2008 | Rev Endocr Metab Disord2008，9，3： | 1 |
| 10 | Maternal nutrition, intrauterine programming and consequential risks in the offspring显示文摘 | Yajnik CS Deshmukh US | 2008 | Rev Endocr Metab Disord2008，9，3： | 1 |
| 11 | Micronutrients and fetal growth显示文摘 | Fall C H Yajnik C S Rao S Davies A A Brown N Farrant H J | 2003 | J Nutr2003，133，52： | 1 |
| 12 | The effect of play in the joints of a function generating mechanism显示文摘 | KOTHALKAR S A YAJNIK K S | 1970 | Journal of Mechanisms1970，5，4： | 1 |
| 13 | Case report:cystitis glandularis mimics bladder tumour:a case report and diagnostic characteristics显示文摘 | Lee G Tsiriopoulos I Yajnik K | 2005 | Int Urol Nephrol2005，37，4： | 1 |
| 14 | Vitamin B12 deficiency and hyperhomocysteinemia in rural and urban Indians 显示文摘 | Yajnik CS Deshpande SS Lubree HG | 2006 | JAPI2006，54，： | 1 |
| 15 | Insulin resistance syndrome in 8-year old Indian children: small at birth, big at 8 years, or both? 显示文摘 | Bavdekar A Yajnik CS Fall GHD | 1999 | Diabetes1999，48，12： | 1 |
| 16 | Effects of Cancer Treatment on Inflammatory Bowel Disease Remission and Reactivation显示文摘 | Jordan E. Axelrad Sharyle A. Fowler Sonia Friedman Ashwin N. Ananthakrishnan Vijay Yajnik | 2012 | Clinical Gastroenterology and Hepatology2012，，9： | 1 |
| 17 | Experiments on swirling turbulent flows-part 1: similarity in swirling flows显示文摘 | Yajnik K S Subbaiah M V | 1973 | Journal of Fluid Mechanics1973，60，4： | 1 |
| 18 | Case report: cystitis glandularismimics bladder tumour: a case report and diagnostic characteristics显示文摘 | Lee G Tsiriopoulos I Yajnik K | 2005 | Int Urol Nephrol2005，37，4： | 1 |
| 19 | FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians显示文摘 | Yajnik C S Janipalli C S Bhaskar S | | 0，，02： | 1 |
| 20 | Maternal nutrition,intrauterine programming and consequential risks in the offspring显示文摘 | Yajnik C S Deshmukh U S | 2008 | Rev Endocr Metab Disord2008，9，3： | 1 |
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