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18篇 您的检索式:作者名="Yan IK"
    题名 作者 年代 出处 被引量
1Intercellular Nanovesicle-Medi- ated microRNA transfer: a mechanism of environmental modula- tion of hepatocellular cancer cell growth显示文摘Kogure T Lin WL Yan IK 2011Hepatology2011,54,4:1
2Protein kinase D1 regulates matrix metallo proteinase expression and inhibits breast cancer cell invasion显示文摘Eiseler T Dppler H Yan IK 2009Breast Cancer Res2009,11,1:1
3Delineation of biomarkers and molecular pathways of residual effects of fluoxetine treatment in juvenile rhesus monkeys by proteomic profiling显示文摘Fluoxetine(Prozac^(TM))is the only antidepressant approved by the US Food and Drug Administration(FDA)for the treatment of major depressive disorder(MDD)in children.Despite its considerable efficacy as a selective serotonin reuptake inhibitor,the possible long-term effects of fluoxetine on brain development in children are poorly understood.In the current study,we aimed to delineate molecular mechanisms and protein biomarkers in the brains of juvenile rhesus macaques(Macaca mulatta)one year after the discontinuation of fluoxetine treatment using proteomic and phosphoproteomic profiling.We identified several differences in protein expression and phosphorylation in the dorsolateral prefrontal cortex(DLPFC)and cingulate cortex(CC)that correlated with impulsivity in animals,suggesting that the GABAergic synapse pathway may be affected by fluoxetine treatment.Biomarkers in combination with the identified pathways contribute to a better understanding of the mechanisms underlying the chronic effects of fluoxetine after discontinuation in children.Yu Yan Dong Ik Park Anja Horn Mari Golub Christoph W.Turck 2023Zoological Research2023,44,1:1
4Protein Kinase D1 regulates MMP expression and inhibits breast cancer cell invasion显示文摘Eiseler T Doeppler H Yan IK 2009Breast Cancer Res2009,11,1:1
5Modulation of hypoxia-signaling pathways by extracellular linc-RoR显示文摘Takahashi K Yan IK Haga H 2014J Cell Sci2014,127,7:1
6Extracellular vesicle-me- diated transfer of long non-coding RNA ROR modulates chemosen- sitivity in human hepatocellular cancer 显示文摘Takahashi K Yan IK Kogure T 2014FEBS open Bio2014,4,:1
7Loss of cell-cell contacts in- duced NF-xB via RhoA-mediated activation of protein kinase DI 显示文摘Cowell CF Yan IK Eiseler T 2009J Cell Biochem2009,106,4:1
8Intercellular nanovesicle - me- diated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth 显示文摘Kogure T Lin WL Yan IK et 01 2011Hepatology2011,54,:1
9Intercellular nanovesi- cle-mediated microRNA transfer : a mechanism of environ mental modulation of hepatocellular cancer cell growth显示文摘Kogure T Lin WL Yan IK 2011Hepatology2011,54,4:1
10Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth显示文摘KOGURE T LIN WL YAN IK 2011Hepatology2011,54,4:1
11Intercellular nanovesicle- mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth 显示文摘Kogure T Lin WL Yan IK 2011Hepatology2011,54,4:1
12Tumour cell -de- rived extracellular vesicles interact with mesenchymal stem cells to modulate the microenvironment and en- hance cholangiocarcinoma growth 显示文摘Haga H Yan IK Takahashi K 2015Extracell Vesicles2015,4,24:1
13Involvement of extracellular vesicle long noncoding RNA(linc-VLDLR)in tumor cell responses to chemotherapy显示文摘Takahashi K Yan IK Wood J 2014Mol Cancer Res2014,12,10:1
14Protein kinase D1 regulates eofilin-mediated F-aetin reorganization and cell motility through slingshot 显示文摘Eiseler T Doppler H Yan IK 2009Nat Cell Biol2009,11,5:1
15Extracellular vesicle-medi- ated transfer of long non-coding RNA ROR modulates cbemosensi- tivity in human hepatocellular cancer显示文摘Takahashi K Yan IK Kogure T 2014FEBS Open Bio2014,4,:1
16Involvement of extracellular vesicle long noncoding RNA(linc-VLDLR)in tumor cell responses to chemotherapy显示文摘Takahashi K Yan IK Wood J 2014Mol Cancer Res2014,12,10:1
17Intercellular nanovesiclemediated microRN A transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth 显示文摘Kogure T Lin WL Yan IK 2011Hepatology2011,54,4:1
18Extracellular vesicle-mediated transfer of a novel long noncoding RNA TUC339:a mechanism of intercellular signaling in human hepatocellular cancer显示文摘Kogure T Yan IK Lin WL 2013Genes Cancer2013,4,78:1
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