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| 1 | Stem cell-based regenerative opportunities for the liver: State of the art and beyond显示文摘The existing mismatch between the great demand for liver transplants and the number of available donor organs highlights the urgent need for alternative therapeutic strategies in patients with acute or chronic liver failure. The rapidly growing knowledge on stem cell biology and the intrinsic repair processes of the liver has opened new avenues for using stem cells as a cell therapy platform in regenerative medicine for hepatic diseases. An impressive number of cell types have been investigated as sources of liver regeneration: adult and fetal liver hepatocytes,intrahepatic stem cell populations,annex stem cells,adult bone marrow-derived hematopoietic stem cells,endothelial progenitor cells,mesenchymal stromal cells,embryonic stem cells,and induced pluripotent stem cells. All these highly different cell types,used either as cell suspensions or,in combination with biomaterials as implantable liver tissue constructs,have generated great promise for liver regeneration. However,fundamental questions still need to be addressed and critical hurdles to be overcome before liver cell therapy emerges. In this review,we summarize the state-of-the-art in the field of stem cell-based therapies for the liver along with existing challenges and future perspectives towards a successful liver cell therapy that will ultimately deliver its demanding goals. | Eleftheria Tsolaki Evangelia Yannaki | 2015 | World Journal of Gastroenterology2015，21，43： | 16 |
| 2 | G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs 显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，： | 1 |
| 3 | Development of virus vectors for gene therapy of beta chain hemoglobinopathies:flanking with a chromatin insulator reduces gamma-globin gene silencing in vivo显示文摘 | Emery DW Yannaki E Tubb J | 2002 | Blood2002，100，6： | 1 |
| 4 | Veno-occlusive disease prophylaxis with fresh frozen plasma and heparin in bone marrow transplantation显示文摘 | BATSIS I YANNAKI E KALOYANNIDIS P | 2005 | Thromb Res2005，2，： | 1 |
| 5 | G-CSF-primed hematopoietic stem ceils or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs 显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，1： | 1 |
| 6 | G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury,predominantly by promoting endogenous repair programs显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，1： | 1 |
| 7 | G-CSF-primed hematopoietic stem cells or G-CSF perse accelerate recovery and improve suivival after injury,predominantly by promoting endogenous repair programs显示文摘 | Yannaki E Athanasiou E Xagorari A | | 0，，： | 1 |
| 8 | G-CsF-Primed hematopeietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury,predominantly by promoting endogenous repair programs显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，1： | 1 |
| 9 | A chromatin insulator protects retrovirus vectors from chromosomal position effects 显示文摘 | Emery D W Yannaki E Tubb J | 2000 | Proc Natl Acad Sci USA2000，97，16： | 1 |
| 10 | G CSF-primed hematopoietic stem cells or G CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，1： | 1 |
| 11 | G-CSF-primed hema-topoietic stem cells or G-CSF per se accelerate recovery and improvesurvival after liver injury,predominantly by pro-moting endogenousrepair programs显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，1： | 1 |
| 12 | Lasting amelio ration in the clinical course of decompensated al coholic cirrhosis with boostinfusions of mobilized peripheral blood stem cells显示文摘 | Yannaki E Anagnostopoulos A Kapetanos D | 2006 | Exp Hematol2006，34，3： | 1 |
| 13 | Veno-occlusive disease prophylaxis with fresh frozen plasma and heparin in bone marrow transplantation 显示文摘 | Batsis I Yannaki E Kaloyannidis P | 2006 | Thromb Res2006，118，5： | 1 |
| 14 | G-CSF-Primed hematopeietic stem cells or G-CSF per se accelerate recovery and Improve survival after liver injury,predominantly by promoting endogenous repair programs显示文摘 | YANNAKI E ATHANASIOU E XAGORARI A | 2005 | Exp Hematol2005，33，： | 1 |
| 15 | Hematopoietic stem cells and liver regeneration: Differentially acting hematopoietic stem cell mobilization agents reverse induced chronic liver injury显示文摘 | Eleftheria Tsolaki Evangelia Athanasiou Eleni Gounari Nikolaos Zogas Eleni Siotou Minas Yiangou Achilles Anagnostopoulos Evangelia Yannaki | 2014 | Blood Cells, Molecules and Diseases2014，，： | 1 |
| 16 | G-CSF- primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs 显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，1： | 1 |
| 17 | G-CSF primed hematopoietie stem cells or G-CSF perse accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs 显示文摘 | Yannaki E Athanasiou E Xagoratti A | 2005 | Exp Hematol2005，33，1： | 1 |
| 18 | Spontaneous adrenal haemorrhage as a manifestation of isolated relapse of non-Hodgkin's lymphoma显示文摘 | Kartsios C Kaloyannidis P Yannaki E | 2003 | Acta Haematol2003，110，4： | 1 |
| 19 | G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury,predominantly by promoting endogenous repair programs显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，1： | 1 |
| 20 | G-CSF primed hema- topoietic stem cells or G-CSF perse accelerate recovery and im- prove survival after liver injury, predominantly by promoting en- dogenous repair programs显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hernatol2005，33，1： | 1 |
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