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| 1 | An experimental study of the dual-loop control of electro-hydraulic load simulator (EHLS)显示文摘This paper investigates motion coupling disturbance(the so called surplus torque)in the hardware-in-the-loop(HIL)experiments.The‘‘velocity synchronization scheme’’was proposed by Jiao for an electro-hydraulic load simulator(EHLS)in 2004.In some situations,however,the scheme is limited in the implementation for certain reasons,as is the case when the actuator’s valve signal is not available or it is seriously polluted by noise.To solve these problems,a‘‘dual-loop scheme’’is developed for EHLS.The dual-loop scheme is a combination of a torque loop and a position synchronization loop.The role of the position synchronization loop is to decouple the motion disturbance caused by the actuator system.To verify the feasibility and effectiveness of the proposed scheme,extensive simulations are performed using AMESim.Then,the performance of the developed method is validated by experiments. | Wang Chengwen Jiao Zongxia Wu Shuai Shang Yaoxing | 2013 | Chinese Journal of Aeronautics2013，26，6： | 15 |
| 2 | m6A RNA modification controls autophagy through upregulating ULK1 protein abundance显示文摘 | Shouheng Jin Xiya Zhang Yanyan Miao Puping Liang Kaiyu Zhu Yuanchu She Yaoxing Wu Di-Ao Liu Junjiu Huang Jian Ren Jun Cui | 2018 | Cell Research2018，28，9： | 12 |
| 3 | A practical nonlinear robust control approach of electro-hydraulic load simulator显示文摘This paper studies a nonlinear robust control algorithm of the electro-hydraulic load simulator(EHLS). The tracking performance of the EHLS is mainly limited by the actuator's motion disturbance, flow nonlinearity, and friction, etc. The developed controller is developed based on the nonlinear motion loading model. The problems of the actuator's disturbance and flow nonlinearity are considered. To address the friction problem, the friction model of the loading motor is identified experimentally. The friction disturbance is compensated using the obtained friction model. Therefore, this paper considers the main three factors comprehensively. The developed algorithm is easy to apply since the controller can be obtained just with one step back-stepping design. The stability of the developed algorithm is proven via Lyapunov analysis. Both co-simulation and experiments are performed to verify the effectiveness of this method. | Wang Chengwen Jiao Zongxia Wu Shuai Shang Yaoxing | 2014 | Chinese Journal of Aeronautics2014，27，3： | 10 |
| 4 | Analysis of the dynamic performance of an electro-hydrostatic actuator and improvement methods显示文摘As a kind of actuation mechanism for power-by-wire(PBW) actuation systems of more/all electrical aircraft, an electro-hydrostatic actuator(EHA) is a highly integrated local hydraulic actuation system. It is a volume control system consisting of a motor, a pump, an actuator, etc.,which has features of high efficiency and reliability. However, the poor dynamic characteristic is one of the main factors restricting its wide application in aircraft. In this paper, the reason for the poor dynamic characteristic of an EHA is revealed from the perspectives of the natural frequency characteristic and the power requirement, respectively. In other words, the insufficiency of the motor output power at a high frequency is the main factor causing the poor dynamic characteristic of the system, and methods which include increasing the maximum output torque of the motor, reducing the rotational inertia of the motor-pump group, and adopting a double-motorpump group configuration are proposed in this paper, by which the dynamic characteristic of the system can be improved. The feasibility of those methods are verified by simulations. Finally, the dynamic characteristic is tested on an EHA prototype, and results show that saturation of the output torque of the motor is the main factor restricting the dynamic characteristic of the EHA system. | Zhihui LI Yaoxing SHANG Zongxia JIAO Yan LIN Shuai WU Xiaobin LI | 2018 | Chinese Journal of Aeronautics2018，31，12： | 9 |
| 5 | High-effciency aircraft antiskid brake control algorithm via runway condition identification based on an on-off valve array显示文摘The aircraft antiskid braking system is an important hydraulic system for preventing tire bursts and ensuring safe take-off and landing. The brake system adjusts the force applied on the brake discs by controlling the brake pressure. Traditional aircraft antiskid braking systems achieve antiskid performance by controlling the braking pressure with an electrohydraulic servo valve.Because the pilot stage of an electrohydraulic servo valve is easily blocked by carbonized hydraulic oil, the servo valve would become a dangerous weak point for aircraft safety. This paper proposes a new approach that uses an on-off valve array to replace the servo valve for pressure control. Based on this new pressure control component, an efficient antiskid control algorithm that can utilize this discontinuous feature is proposed. Furthermore, the algorithm has the ability to identify the runway circumstances. To overcome the discontinuity in the process of using an on-off valve array, the Filippov framework is introduced. The conditions of convergence of the system are also discussed.The results of the digital simulations and the hardware-in-the-loop(HIL) braking experiments are used to verify the efficiency and stability of the proposed control algorithm. The method also proves that the on-off valve array can replace the servo valve perfectly as a new type of antiskid braking pressure control component. | Dong SUN Zongxia JIAO Yaoxing SHANG Shuai WU Xiaochao LIU | 2019 | Chinese Journal of Aeronautics2019，32，11： | 7 |
| 6 | Main protease of SARS-CoV-2 serves as a bifunctional molecule in restricting type I interferon antiviral signaling显示文摘Dear Editor,At present,the world is suffering from an ongoing pandemic of 2019 novel coronavirus(COVID-19)which is caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2/2019-nCoV).To date,>20 million cases were confirmed with a death toll at>700,000.Although there are no clinically specific and effective antiviral treatments toward SARS-CoV-2 infection so far,the pathological study of SARS-CoV-2 infection and the development of SARS-CoV-2-specific vaccines are progressing rapidly within these several months.1 However,few reports mentioned the mechanism employed by SARS-CoV-2 for evading from surveillance of immune system. | Yaoxing Wu Ling Ma Zhen Zhuang Sihui Cai Zhiyao Zhao Lingli Zhou Jing Zhang Pei-Hui Wang Jincun Zhao Jun Cui | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 4 |
| 7 | A novel integrated self-powered brake system for more electric aircraft显示文摘Traditional hydraulic brake systems require a complex system of pipelines between an aircraft engine driven pump(EDP) and brake actuators, which increases the weight of the aircraft and may even cause serious vibration and leakage problems. In order to improve the reliability and safety of more electric aircraft(MEA), this paper proposes a new integrated self-powered brake system(ISBS) for MEA. It uses a hydraulic pump geared to the main wheel to recover a small part of the kinetic energy of a landing aircraft. The recovered energy then serves as the hydraulic power supply for brake actuators. It does not require additional hydraulic source, thus removing the pipelines between an EDP and brake actuators. In addition, its self-powered characteristic makes it possible to brake as usual even in an emergency situation when the airborne power is lost. This paper introduces the working principle of the ISBS and presents a prototype. The mathematical models of a taxiing aircraft and the ISBS are established. A feedback linearization control algorithm is designed to fulfill the anti-skid control. Simulations are carried out to verify the feasibility of the ISBS, and experiments are conducted on a ground inertia brake test bench. The ISBS presents a good performance and provides a new potential solution in the field of brake systems for MEA. | Yaoxing SHANG Xiaochao LIU Zongxia JIAO Shuai WU | 2018 | Chinese Journal of Aeronautics2018，31，5： | 4 |
| 8 | Ground maneuver for front-wheel drive aircraft via deep reinforcement learning显示文摘The maneuvering time on the ground accounts for 10%–30%of their flight time,and it always exceeds 50%for short-haul aircraft when the ground traffic is congested.Aircraft also contribute significantly to emissions,fuel burn,and noise when taxiing on the ground at airports.There is an urgent need to reduce aircraft taxiing time on the ground.However,it is too expensive for airports and aircraft carriers to build and maintain more runways,and it is space-limited to tow the aircraft fast using tractors.Autonomous drive capability is currently the best solution for aircraft,which can save the maneuver time for aircraft.An idea is proposed that the wheels are driven by APU-powered(auxiliary power unit)motors,APU is working on its efficient point;consequently,the emissions,fuel burn,and noise will be reduced significantly.For Front-wheel drive aircraft,the front wheel must provide longitudinal force to tow the plane forward and lateral force to help the aircraft make a turn.Forward traction effects the aircraft’s maximum turning ability,which is difficult to be modeled to guide the controller design.Deep reinforcement learning provides a powerful tool to help us design controllers for black-box models;however,the models of related works are always simplified,fixed,or not easily modified,but that is what we care about most.Only with complex models can the trained controller be intelligent.High-fidelity models that can easily modified are necessary for aircraft ground maneuver controller design.This paper focuses on the maneuvering problem of front-wheel drive aircraft,a high-fidelity aircraft taxiing dynamic model is established,including the 6-DOF airframe,landing gears,and nonlinear tire force model.A deep reinforcement learning based controller was designed to improve the maneuver performance of front-wheel drive aircraft.It is proved that in some conditions,the DRL based controller outperformed conventional look-ahead controllers. | Hao ZHANG Zongxia JIAO Yaoxing SHANG Xiaochao LIU Pengyuan QI Shuai WU | 2021 | Chinese Journal of Aeronautics2021，34，10： | 2 |
| 9 | RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-kB hyper-activation and inflammation显示文摘The ongoing 2019 novel coronavirus disease(COVID-19)caused by SARS-CoV-2 has posed a worldwide pandemic and a major global public health threat.The severity and mortality of COVID-19 are associated with virus-induced dysfunctional inflammatory responses and cytokine storms.However,the interplay between host inflammatory responses and SARS-CoV-2 infection remains largely unknown.Here,we demonstrate that SARS-CoV-2 nucleocapsid(N)protein,the major structural protein of the virion,promotes the virus-triggered activation of NF-kB signaling.After binding to viral RNA,N protein robustly undergoes liquid-liquid phase separation(LLPS),which recruits TAK1 and IKK complex,the key kinases of NF-kB signaling,to enhance NF-kB activation.Moreover,1,6-hexanediol,the inhibitor of LLPS,can attenuate the phase separation of N protein and restrict its regulatory functions in NF-kB activation.These results suggest that LLPS of N protein provides a platform to Induce NF-kB hyper-activation,which could be a potential therapeutic target against COVID-19 severe pneumonia. | Yaoxing Wu Ling Ma Sihui Cai Zhen Zhuang Zhiyao Zhaou Shouheng Jin Weihong Xie Lingli Zhou Lei Zhang Jincun Zhao Jun Cui | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 2 |
| 10 | Low temperature catalytic combustion of chlorobenzene over Mn–Ce–O/γ-Al 2 O 3 mixed oxides catalyst显示文摘 | Meng Wu Xingyi Wang Qiguang Dai Yaoxing Gu Dao Li | 2010 | Catalysis Today2010，，： | 1 |
| 11 | Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex显示文摘Currently,the incidence and fatality rate of SARS-CoV-2 remain continually high worldwide.COVID-19 patients infected with SARS-CoV-2 exhibited decreased type I interferon(IFN-I)signal,along with limited activation of antiviral immune responses as well as enhanced viral infectivity.Dramatic progresses have been made in revealing the multiple strategies employed by SARS-CoV-2 in impairing canonical RNA sensing pathways.However,it remains to be determined about the SARS-CoV-2 antagonism of cGAS-mediated activation of IFN responses during infection.In the current study,we figure out that SARS-CoV-2 infection leads to the accumulation of released mitochondria DNA(mtDNA),which in turn triggers cGAS to activate IFN-I signaling.As countermeasures,SARS-CoV-2 nucleocapsid(N)protein restricts the DNA recognition capacity of cGAS to impair cGAS-induced IFN-I signaling.Mechanically,N protein disrupts the assembly of cGAS with its co-factor G3BP1 by undergoing DNA-induced liquid-liquid phase separation(LLPS),subsequently impairs the double-strand DNA(dsDNA)detection ability of cGAS.Taken together,our findings unravel a novel antagonistic strategy by which SARS-CoV-2 reduces DNA-triggered IFN-I pathway through interfering with cGAS-DNA phase separation. | Sihui Cai Chenqiu Zhang Zhen Zhuang Shengnan Zhang Ling Ma Shuai Yang Tao Zhou Zheyu Wang Weihong Xie Shouheng Jin Jincun Zhao Xiangdong Guan Jianfeng Wu Jun Cui Yaoxing Wu | 2023 | Signal Transduction and Targeted Therapy2023，8，5： | 1 |
| 12 | Low temperature catalytic combustion of chlorobenzene over Mn–Ce–O/γ-Al 2 O 3 mixed oxides catalyst显示文摘 | Meng Wu Xingyi Wang Qiguang Dai Yaoxing Gu Dao Li | 2010 | Catalysis Today2010，，3： | 1 |
| 13 | 选择性细胞自噬的免疫调控作用显示文摘文章简介细胞自噬是真核生物体内降解细胞器、外源微生物和蛋白的一项基本生理活动,与诸多生理病理过程密切相关。 | Shouheng Jin Shuo Tian Man Luo Weihong Xie Tao Liu Tianhao Duan Yaoxing Wu 崔隽 | 2018 | 科学新闻2018，0，4： | 0 |
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