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| 1 | Effect of Lichong decoction on expression of Bcl-2 and Bcl-2-associated X protein mRNAs in hysteromyoma model rat显示文摘OBJECTIVE:To study on effects of Lichong decoction on expression of apoptosis-controlling genes,Bcl-2 and Bcl-2-associated X protein(Bax) mRNAs in hysteromyoma tissue of the hysteromyoma model rat.METHODS:Fifty Wistar female rats were randomly divided into a normal group,a model group,a Lichong decoction group,a Guizifuling capsule group and a Mifepristone group.The hysteromyoma rat model was established by intraperitoneal injection of exogenous estrin and progestogens.Pathological examination of uterine tissue,uterine coefficient and uterine transverse diameter were made under optic microscope and expressions of Bcl-2 and Bax mRNAs in uterine tissue in the groups were detected with real-time fluorescent quantitative polymerase chain reaction(PCR) technique.RESULTS:After treatment,under microscope it was found that in the Lichong decoction group myometrium thinned,muscle fiber slightly overgrowth or long and thin,regular arrangement,inserting phenomenon of inner circular muscle and external longitudinal muscle was occasionally or not seen in the Lichong decoction group.The uterine coefficient and the uterine transverse diameter significantly decreased(P<0.01),and Bcl-2 mRNA expression significantly decreased(P<0.01) and Bax mRNA expression significantly increased in hysteromyoma tissue(P<0.01) in the Lichong decoction group as compared with the model group.CONCLUSION:Therapeutic effects of Lichong decoction on hysteromyoma is related with decrease of Bcl-2 mRNA expression and increase of Bax mRNA expression. | Donghua Li Xin Xu Ruiya Qian Jianguo Geng Yan Zhang Xiaolei Xie Yasong Wang Xiaoli Zou | 2013 | Journal of Traditional Chinese Medicine2013，33，2： | 24 |
| 2 | 基于TPB和VBN的低碳旅游生活行为影响因素研究模型构建初探显示文摘在文献研究和对旅游活动的特点分析的基础上,提出了低碳旅游生活行为意愿、低碳旅游生活行为态度、主观规范、知觉行为控制、习惯、旅游中的情境、悠逸诉求可能影响低碳旅游生活行为,在计划行为理论和价值-信念-规范理论为理论框架下构建了'低碳旅游生活行为影响因素分析模型',并为模型中的潜变量观测变量设计了测量题项。 | 黄雪丽 路正南 Yasong (Alex) WANG | 2013 | 科技管理研究2013，33，21： | 16 |
| 3 | Lichong decoction reduces Matrix Metalloproteinases-2 expression but increases Tissue Inhibitors of Matrix Metalloproteinases-2 ex-pression in a rat model of uterine leiomyoma显示文摘OBJECTIVE:To study the effect of Lichong decoction(LD) on expression of matrix metalloproteinase-2(MMP-2) and metalloproteinase-2(TIMP-2) in a rat model of uterine leiomyoma(UL).METHODS:UL was induced in rats using exogenous estrogen and progesterone.LD was administered(p.o.) for 4 weeks,and mifepristone(RU-486)used as a control.To observe the effect of LD on the uterine coefficient and uterine transverse diameter,a radioimmunoassay method was used to detect serum levels of sex hormones.Light microscopic analyses of pathologic changes in the tissues of UL rats were evaluated.Expression of the proteins of matrix metalloproteinases(MMPs) and tissue inhibitors of metalloproteinases(TIMPs) in uterine tissues was assessed by immunohistochemical staining and western blotting.RESULTS:A UL model in rats was established successfully.LD reduced uterine weight,uterine coefficient,and uterine transverse diameter compared with untreated controls.LD reduced levels of estradiol,progesterone,follicle-stimulating hormone,and luteinizing hormone in our UL models.LD improved the pathologic condition of uterine muscle.Expression of MMP-2 protein decreased to varying extents in LD-treated groups,but TIMP-2 levels were enhanced.LD appears to reduce MMP-2 expression and increase TIMP-2 expression in UL tissue.CONCLUSION:These data suggest that the mechanism of action of LD on ULs may involve reduction of MMP-2 expression and increase in TIMP-2 expression in rats. | Wang Yasong Li Donghua Xu Xin Qian Ruiya Zhang Yalan Huang Yuhua Geng Jianguo Zou Xiaoli Han Hon-gjuan Zhang Wufang | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 12 |
| 4 | Effect of Lichong Decoction on expression of IGF-I and proliferating cell nuclear antigen mRNA in rat model of uterine leiomyoma显示文摘OBJECTIVE:To study the effect of Lichong Decoction(Lichong Decoction for strengthening anti-pathogenic Qi and eliminating blood stasis) on the expression of insulin-like growth factor-I(IGF-I) and proliferating cell nuclear antigen(PCNA) mRNA in a rat model of uterine leiomyoma.METHODS:Fifty female Wistar rats were randomized into a normal control group,model group,Lichong Decoction group,Guizhifuling Capsule(Capsule containing Cassia Twig and Poria) group,and Mifepristone group.The uterine leiomyoma model was established by peritoneal injections of exogenous estrogen and progesterone hormone.The ultrastructural changes in cells of rat uterine tissues were observed with transmission electron microscopy,and the expression of IGF-I and PCNA mRNA was detected by real-time fluorescent quantitative PCR.RESULTS:Following treatment,cells in the Lichong Decoction group appeared to be arranged normally,the cellular morphology were almost in a normal state,hyperplasia and hypertrophy of the chondriosome was reduced,collagen fibers were arranged in a regular manner,without obvious hyperplasia,and the expression of IGF-I and PCNA mRNA was significantly decreased compared with the model group(P<0.01).CONCLUSIONS:The effect of Lichong Decoction on uterine leiomyoma is related to its function in reducing the expression of IGF-I and PCNA mRNA. | Donghua Li Yalan Zhang Hongjuan Han Jianguo Geng Xiaolei Xie Jiubo Zheng Yasong Wang Xiaoli Zou | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 11 |
| 5 | Bioinspired Dry Adhesive Materials and Their Application in Robotics: A Review显示文摘 | Yasong Li Jeffrey Krahn Carlo Menon | 2016 | Journal of Bionic Engineering2016，13，2： | 11 |
| 6 | Stationary flow fields prediction of variable physical domain based on proper orthogonal decomposition and kriging surrogate model显示文摘In this paper a new flow field prediction method which is independent of the governing equations, is developed to predict stationary flow fields of variable physical domain. Predicted flow fields come from linear superposition of selected basis modes generated by proper orthogonal decomposition(POD). Instead of traditional projection methods, kriging surrogate model is used to calculate the superposition coefficients through building approximate function relationships between profile geometry parameters of physical domain and these coefficients. In this context,the problem which troubles the traditional POD-projection method due to viscosity and compressibility has been avoided in the whole process. Moreover, there are no constraints for the inner product form, so two forms of simple ones are applied to improving computational efficiency and cope with variable physical domain problem. An iterative algorithm is developed to determine how many basis modes ranking front should be used in the prediction. Testing results prove the feasibility of this new method for subsonic flow field, but also prove that it is not proper for transonic flow field because of the poor predicted shock waves. | Qiu Yasong Bai Junqiang | 2015 | Chinese Journal of Aeronautics2015，28，1： | 10 |
| 7 | Characteristics of ozone pollution and the sensitivity to precursors during early summer in central plain, China显示文摘In this study,we conducted an observation experiment from May 1 to June 30,2018 in Zhengzhou,a major city in central China,where ground ozone(O3)pollution has become serious in recent years.The concentrations of O3 and its precursors,as well as H2O_(2) and meteorological data were obtained from the urban site(Yanchang,YC),suburban(Zhengzhou University,ZZU)and background sites(Ganglishuiku,GLSK).Result showed that the rates of O3 concentration exceeded Chinese National Air Quality Standard GradeⅡ(93.3 ppbv)were 59.0%,52.5%,and 55.7%at the above three sites with good consistency,respectively,indicating that O3 pollution is a regional problem in Zhengzhou.The daily peak O3 appeared at 15:00-16:00,which was opposite to VOCs,NOx,and CO and consistent with H2O_(2).The exhaustive statistical analysis of meteorological factors and chemical effects on O3 formation at YC was advanced.The high concentration of precursors,high temperature,low relative humidity,and moderately high wind speed together with the wind direction dominated by south and southeast wind contribute to urban O3 episodes in Zhengzhou.O3 formation analysis showed that reactive alkenes such as isoprene and cis-2-butene contributed most to O3 formation.The VOCs/NOx ratio and smog production model were used to determine O3-VOC-NOx sensitivity.The O3 formation in Zhengzhou during early summer was mainly under VOC-limited and transition regions alternately,which implies that the simultaneous emission reduction of alkenes and NOx is effective in reducing O3 pollution in Zhengzhou. | Yasong Li Shasha Yin Shijie YU Ling Bai Xudong Wang Xuan Lu Shuangliang Ma | 2021 | Journal of Environmental Sciences2021，33，1： | 10 |
| 8 | Global aerodynamic design optimization based on data dimensionality reduction显示文摘In aerodynamic optimization, global optimization methods such as genetic algorithms are preferred in many cases because of their advantage on reaching global optimum. However,for complex problems in which large number of design variables are needed, the computational cost becomes prohibitive, and thus original global optimization strategies are required. To address this need, data dimensionality reduction method is combined with global optimization methods, thus forming a new global optimization system, aiming to improve the efficiency of conventional global optimization. The new optimization system involves applying Proper Orthogonal Decomposition(POD) in dimensionality reduction of design space while maintaining the generality of original design space. Besides, an acceleration approach for samples calculation in surrogate modeling is applied to reduce the computational time while providing sufficient accuracy. The optimizations of a transonic airfoil RAE2822 and the transonic wing ONERA M6 are performed to demonstrate the effectiveness of the proposed new optimization system. In both cases, we manage to reduce the number of design variables from 20 to 10 and from 42 to 20 respectively. The new design optimization system converges faster and it takes 1/3 of the total time of traditional optimization to converge to a better design, thus significantly reducing the overall optimization time and improving the efficiency of conventional global design optimization method. | Yasong QIU Junqiang BAI Nan LIU Chen WANG | 2018 | Chinese Journal of Aeronautics2018，31，4： | 7 |
| 9 | A fatigue damage model for rock salt considering the effects of loading frequency and amplitude显示文摘With the large-scale construction of underground gas storage in salt deposit, much more efforts have been made to assess the fatigue properties of rock salt. The fatigue damage processes the primary, steady,and accelerated phases, which is similar to the axial irrecoverable deformation compiled from the loci of the loading cycles of rock salt. The cumulative fatigue damage increases with a decrease in the loading frequency and with an increase in the stress amplitude within the range tested. To take into account the effects of loading frequency and amplitude on the fatigue behavior of rock salt subjected to cyclic loading, a low cycle fatigue damage model was exclusively established combined with the Manson–Coffin formula. The proposed damage evolution equation was validated with experimental results and proved to be efficient in the prediction of fatigue damage tendency of rock salt under different loading frequencies and amplitudes. | Wang Yasong Ma Linjian Fan Pengxian Chen Yan | 2016 | International Journal of Mining Science and Technology2016，26，5： | 6 |
| 10 | Assessment of deep groundwater over-exploitation in the North China Plain显示文摘A series of environmental—geological problems have been caused by over-exploitation of deep groundwater(i.e.,confined aquifer water) in the North China Plain.In order to better understand the status of deep groundwater over-exploitation and the resultant environmental—geological problems on a regional scale,the over-exploitation of groundwater has been assessed by way of the groundwater exploitation potential coefficient(i.e.,the ratio of exploitable amount of deep groundwater to current exploitation), cumulative land subsidence,and long-term average lowering rate of the groundwater table.There is a good correlation among the results calculated by the different methods.On a regional scale,deep groundwater has been over-exploited and there is no further exploitation potential under the current conditions.The groundwater exploitation degree index takes the exploitation in 2003 as the reference for the calculations, so the results mainly reflect the degree of current groundwater exploitation.The results of over-exploitation of deep groundwater obtained by land subsidence data and long-term average rate of depression of the water table mainly reflect environmental—geological problems caused by exploitation of deep groundwater. | Jiansheng Shi Zhao Wang Zhaoji Zhang Yuhong Fei Yasong Li Feng'e Zhang Jingsheng Chen Yong Qian | 2011 | Geoscience Frontiers2011，2，4： | 5 |
| 11 | Should antidepressants be used to treat childhood depression?显示文摘 | Yasong DU | 2013 | 上海精神医学2013，25，1： | 4 |
| 12 | Effects of Si Addition on Microstructure,Properties and Serration Behaviors of Lightweight Al-Mg-Zn-Cu Medium-entropy Alloys显示文摘A series of as-cast lightweight multicomponent alloys Al(86-x)Mg10Zn2Cu2Six(x=0,0.3,0.6,0.9,1.2 at.%)were prepared by a vacuum induction furnace with a steel die.With the addition of Si,the reticular white Al-Cu phase deposited were gradually replaced by the gray eutectic Mg-Si phase,while the compressive strength of the alloys increases first and then decreases slowly.It is particularly noteworthy that the compression plasticity also exhibits this trend.When the Si content is 0.9 at.%,the compressive strength reaches its maximum at 779.11 MPa and the compressive plasticity reaches 20.91%.The effect of the addition of Si on the serration behavior of alloy was also studied;we found that the addition of Si introduces a new MgSi phase,and with the change of Si is significantly affects the morphology of the precipitated phase,which affects the serration behavior of the alloys.The comprehensive mechanical properties of the alloy are optimal at the critical point where the serration behavior disappears.In this work,we have provided a method and a composition for the preparation of a low-cost,high-strength,lightweight medium-entropy alloys. | Yasong Li Ruixuan Li Yong Zhang | 2019 | Research and Application of Materials Science2019，1，1： | 3 |
| 13 | Optimal Gait for Bioinspired Climbing Robots Using Dry Adhesion: A Quasi-Static Investigation显示文摘 | Paolo Boscariol Michael A. Henrey Yasong Li Carlo Menon | 2013 | Journal of Bionic Engineering2013，10，1： | 3 |
| 14 | Self-adjusting decision feedback equalizer for variational underwater acoustic channel environments显示文摘Aimed at the abominable influences to blind equalization algorithms caused by complex timespace variability existing in underwater acoustic channels, a new selfadjusting decision feedback equalization(DFE) algorithm adapting to different underwater acoustic channel environments is proposed by changing its central tap position. Besides, this new algorithm behaves faster convergence speed based on the analysis of equalizers' working rules, which is more suitable to implement communications in different unknown channels. Corresponding results and conclusions are validated by simulations and spot experiments. | Yasong Luo Zhong Liu Shengliang Hu Jingbo He | 2014 | Journal of Systems Engineering and Electronics2014，25，1： | 3 |
| 15 | Parenting stress and affective symptoms in parents of autistic children显示文摘We examined parenting stress and mental health status in parents of autistic children and assessed factors associated with such stress. Participants were parents of 188 autistic children diagnosed with DSM-IV criteria and parents of 144 normally developing children. Parents of autistic children reported higher levels of stress, depression, and anxiety than parents of normally developing children. Mothers of autistic children had a higher risk of depression and anxiety than that did parents of normally developing children. Mothers compared to fathers of autistic children were more vulnerable to depression. Age, behavior problems of autistic children, and mothers' anxiety were significantly associated with parenting stress. | GONG Yun DU YaSong LI HuiLin ZHANG XiYan AN Yu WU Bai-Lin | 2015 | Science China(Life Sciences)2015，58，10： | 3 |
| 16 | Radiation belt electron scattering by whistler-mode chorus in the Jovian magnetosphere: Importance of ambient and wave parameters显示文摘Whistler-mode chorus waves are regarded as an important acceleration mechanism contributing to the formation of relativistic and ultra-relativistic electrons in the Jovian radiation belts. Quantitative determination of the chorus wave driven electron scattering effect in the Jovian magnetosphere requires detailed information of both ambient magnetic field and plasma density and wave spectral property, which however cannot be always readily acquired from observations of existed missions to Jupiter. We therefore perform a comprehensive analysis of the sensitivity of chorus induced electron scattering rates to ambient magnetospheric and wave parameters in the Jovian radiation belts to elaborate to which extent the diffusion coefficients depend on a number of key input parameters. It is found that quasi-linear electron scattering rates by chorus can be strongly affected by the ambient magnetic field intensity, the wave latitudinal coverage, and the peak frequency and bandwidth of the wave spectral distribution in the Jovian magnetosphere, while they only rely slightly on the background plasma density profile and the peak wave normal angle, especially when the wave emissions are confined at lower latitudes. Given the chorus wave amplitude, chorus induced electron scattering rates strongly depend on Jovian L-shell to exhibit a tendency approximately proportional to L_J^3. Our comprehensive analysis explicitly demonstrates the importance of reliable information of both the ambient magnetospheric state and wave distribution property to understanding the dynamic electron evolution in the Jovian radiation belts and therefore has implications for future mission planning to explore the extreme particle radiation environment of Jupiter and its satellites. | BinBin Ni Jing Huang YaSong Ge Jun Cui Yong Wei XuDong Gu Song Fu Zheng Xiang ZhengYu Zhao | 2018 | Earth and Planetary Physics2018，2，1： | 3 |
| 17 | On the source of the quasi-Carrington Rotation periodic magnetic variations on the Martian surface: InSight observations and modeling显示文摘In a recent paper(Luo H et al.,2022),we found that the peak amplitudes of diurnal magnetic variations,measured during martian days(sols)at the InSight landing site,exhibited quasi Carrington-Rotation(qCR)periods at higher eigenmodes of the natural orthogonal components(NOC);these results were based on~664 sols of magnetic field measurements.However,the source of these periodic variations is still unknown.In this paper we introduce the neutral-wind driven ionospheric dynamo current model(e.g.,Lillis et al.,2019)to investigate the source.Four candidates-the draped IMF,electron density/plasma density,the neutral densities,and the electron temperature in the ionosphere with artificial qCR periodicity,are applied in the modeling to find the main factor likely to be causing the observed surface magnetic field variations that exhibit the same qCR periods.Results show that the electron density/plasma density,which controls the total conductivity in the dynamo region,appears to account for the greatest part of the surface qCR variations;its contribution reaches about 67.6%.The draped IMF,the neutral densities,and the electron temperature account,respectively,for only about 12.9%,10.3%,and 9.2%of the variations.Our study implies that the qCR magnetic variations on the Martian surface are due primarily to variations of the dynamo currents caused by the electron density variations.We suggest also that the timevarying fields with the qCR period could be used to probe the Martian interior's electrical conductivity structure to a depth of at least 700 km. | Hao Luo AiMin Du ShaoHua Zhang YaSong Ge Ying Zhang ShuQuan Sun Lin Zhao Lin Tian SongYan Li | 2022 | Earth and Planetary Physics2022，6，3： | 2 |
| 18 | Evolution Characteristics and Influence Factors of Deep Groundwater Depression Cone in North China Plain,China——A Case Studyin Cangzhou Region显示文摘The North China Plain(NCP) is one of the global hotspots of groundwater depletion, groundwater is almost the only source of water for agricultural, industrial and drinking water in this region. After long-term's over-exploitation of deep groundwater, there appeared several deep groundwater depression cones, such as Cangzhou cone, Dezhou cone, Hengshui cone, Tianjin cone, etc., in which the Cangzhou cone is one of the typical cones for its special geography and hydrogeology conditions. In this study, the authors intended to analyze the evolution characteristics and influence factors of deep groundwater depression cone in Cangzhou region, especially the No. III aquifer depression cone, which is the main exploitation zone in this region. Analysis of the evolution of the groundwater depression cone of the No. III aquifer group in Cangzhou region showed that this process can be divided into four stages, namely, development, stable development, rapid expansion, and gradual recovery. The shape and evolution characteristics of the depression cone at different stages are described by analyzing the evolution of the-30,-40, and-50 contours of the groundwater table, for example the closed area of water table contour of-50 m has been enlarged from 95 km2 in 1985 to 6 528.5 km2 in 2005. The dominant factors that affect the evolution characteristics at different stages are proposed. The results showed that relatively long dry periods with less precipitation, special geological and hydrogeological conditions, and sharply increased water consumption for industrial and agricultural development are the main factors that cause the formation of deep groundwater depression cones. Meanwhile, an environmental response against groundwater exploitation is presented, and rational solutions are suggested to avert water crisis. | Yasong Li Fawang Zhang Zhantao Han Ping Wang Honghan Chen Zhaoji Zhang | 2014 | Journal of Earth Science2014，25，6： | 2 |
| 19 | Effect ofBioleaching on the Yield and Composition of Meihekou OilShale(China)显示文摘 | ZHANG Xueqing FEI Yuhong LI Yasong | 2014 | Oil Shale2014，31，2： | 1 |
| 20 | Research Progress on the Mechanism of Groundwater Arsenic Contamination Caused by Animal Feed Additives with Roxarsone显示文摘Firstly,the general situation of arsenic pollution caused by livestock and poultry industry at home and abroad was introduced,and then the transformation and adsorption of roxarsone in the environment were analyzed,finally the control measures of roxarsone pollution was discussed. | Yasong Li Zhaoji Zhang Yuhong Fei Honghan Chen | 2013 | Meteorological and Environmental Research2013，4，10： | 1 |
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