|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Interventional effect of electroacupuncture combined with medicine on monoamine neurotransmitters in hypothalamus of rats with ulcerative colitis显示文摘BACKGROUND: Ulcerative colitis (UC) is conventionally treated with sulfasalazine and other aminosalicylic acids. The symptoms of UC can be rapidly controlled, but high recurrence, severe adverse reactions and other shortages exist commonly. Whether electroacupuncture combined with medicine can make up these shortages remains unclear. OBJECTIVE: This study was to observe the regulatory effect of electroacupuncture combined with medicine on monoamine neurotransmitter in hypothalamus of rats with ulcerative colitis, and to analyze the pathogenesis of UC and the action pathway of electroacupuncture combined with medicine. DESIGN: A randomized controlled observation. SETTING: Shanghai Institute of Acupuncture and Meridian. MATERIALS: Thirty involved male SD rats of clean grade, weighing (200±20)g, were provided by the Experimental Animal Center, Shanghai University of Traditional Chinese Medicine. Sulfasalazine was produced in the Shanghai Sanwei Pharmaceutical Co., Ltd [certification No. (1995)002083]. METHODS: This study was carried out in the State Laboratory (grade 3) for Acupuncture and Immunology, Shanghai Institute of Acupuncture and Meridian. The involved 30 rats were randomized into 5 groups: normal group, model group, electroacupuncture group, medicine group and electroacupuncture combined with medicine group, with 6 rats in each group. Rats in the latter 4 groups were prepared into models of UC. In the electroacupuncture group, Zusanli(shuang) point was selected. Electro-acupuncture apparatus (G6805Ⅱ type) was connected to the point and used to stimulate it with continuous wave, frequency of 2 Hz, electrical intensity 4 mA, 20 minutes a day, for 14 days successively. In the medicine group, rats were intragastrically administrated with sulfasalazine, twice a day, 3 mL once, for 14 days successively. In the electroacupuncture combined with medicine group, rats were treated with electroacupuncture and medicine simultaneously as described in the previous two groups. Rats in the model group and normal control group were untouched except for being fixed. MAIN OUTCOME MEASURES: The levels of noradrenaline acid tartrate (NE), 3-methoxy-4 hydroxyphenylglycol (MHPG), dopamine hydrochloride (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), 5-hydroxytryptamine (5-HT) hydrochloride, homovanillic acid (HVA) and 5-hydroxyindole acetic acid (5-HIAA) of rats in each group were detected by high-performance liquid chromatography (HPLC)-electrochemical method. RESULTS: All the 30 involved rats entered into the stage of final analysis. ①Detection of NE and MHPG levels: After treatment, NE level in the hypothalamus of rats was significantly higher in the electroacupuncture combined with medicine group, electroacupuncture group and medicine group was all significantly higher than that in the model group, respectively (P < 0.01). After treatment, MHPG level in the metabolite of NE was very significantly higher in the electroacupuncture group than in the medicine group (P < 0.01). ②Detection of DA and DOPAC levels: After treatment, DA level in the hypothalamus of rats was very significantly higher in the medicine group than in the model group (P < 0.01). ③Detection of 5-HT, HVA and 5-HIAA levels: After treatment, 5-HIAA level in the hypothalamus of rats was significantly higher in the medicine group than in the model group (P < 0.05). CONCLUSION: The abnormal synthesis and metabolism of monoamine neurotransmitter in the central nervous system is one of pathogenesis of UC. Electroacupuncture combined with medicine might reach its goal of treatment by regulating the monoamine neurotransmitter disorder in the hypothalamus of rats with UC. | Yin Shi Shuang Li Huangan Wu Yi Yao Chen Zhao Zheng Shi Yejing Gong | 2007 | Neural Regeneration Research2007，2，9： | 4 |
| 2 | Electrolyte and current collector designs for stable lithium metal anodes显示文摘With the increasing demand for high energy-density batteries for portable electronics and large-scale energy storage systems,the lithium metal anode(LMA)has received tremendous attention because of its high theoretical capacity and low redox potential.However,the commercial application of LMAs is impeded by the uncontrolled growth of lithium dendrites.Such dendrite growth may result in internal short circuits,detrimental side reactions,and the formation of dead lithium.Therefore,the growth of lithium metal must be controlled.This article summarizes our recent efforts in inhibiting such dendrite growth,decreasing the detrimental side reactions,and elongating the LMA lifespan by optimizing the electrolyte structure and by designing appropriate current collectors.After identifying that the unstable solid electrolyte inter-face(SEI)film is responsible for the potential dropping in carbonate electrolytes,we developed LiPF_(6)-LiNO_(3) dual-salt electrolyte and lithium bis(fluorosulfonyl)imide(LiFSI)-carbonate electrolyte to stabilize the SEI film of LMAs.In addition,we achieved controlled lithium depos-ition by designing the structure and material of the current collectors,including selective lithium deposition in porous current collectors,lithio-philic metal guided lithium deposition,and iron carbide induced underpotential lithium deposition in nano-cavities.The limitations of the cur-rent strategies and prospects for future research are also presented. | Simeng Zhang Gaojing Yang Xiaoyun Li Yejing Li Zhaoxiang Wang Liquan Chen | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，5： | 2 |
| 3 | Effect of activation time on the properties of activated carbons pre- pared by microwave-assisted activation for electric double layer capacitors显示文摘 | Xiaojun He Yejing Genga Jieshan Qiu | 2010 | Carbon2010，48，5： | 1 |
| 4 | Morphotropic phase boundary and electrical properties of K1-xNaxNbO3 lead-free ceramics 显示文摘 | DAI Yejing ZHANG Xiaowen CHEN Kepi | 2009 | Appl Phys Lett2009，94，04： | 1 |
| 5 | Squential Traitor Tracing显示文摘 | Safavi-Naini R Wang Yejing | 2003 | IEEE Trans on Information Theory2003，49，5： | 1 |
| 6 | Effects of heavy metals Cd2% Pb2+and Zn^2+on DNA damage of loach Misgurnus anguillicaudatus显示文摘 | Yingmei ZHANG Yejing WANG Runliu YU | 2007 | Frontiers of Agriculture in China2007，，1： | 1 |
| 7 | Morphotropic phase boundary and electrical properties of K1–xNaxNbO3 lead-freeceramics显示文摘 | DAI Yejing ZHANG Xiaowen CHEN Kepi | 2009 | Appl Phys Lett2009，94，04： | 1 |
| 8 | Preparation of microporous activated carbon and its electrochemical performance for electric double layer capacitor显示文摘 | Xiaojun He Jiangwei Lei Yejing Geng Xiaoyong Zhang Mingbo Wu Mingdong Zheng | 2009 | Journal of Physics and Chemistry of Solids2009，，3： | 1 |
| 9 | Structural analysis of bio-oils from sub-and supercritical water liquefaction of woodybiomass显示文摘 | Qian Yejing Zuo Chengji Tan Jian | 2007 | Energy2007，32，3： | 1 |
| 10 | Collusion secure q-ary fingerprinting for percteptual content显示文摘 | Wang Yejing | 2001 | Lecture Notes in Computer Science2001，2320，： | 1 |
| 11 | Kinetic Limits of Graphite Anode for Fast‑Charging Lithium‑Ion Batteries显示文摘Fast-charging lithium-ion batteries are highly required,especially in reducing the mileage anxiety of the widespread electric vehicles.One of the biggest bottlenecks lies in the sluggish kinetics of the Li^(+)intercalation into the graphite anode;slow intercalation will lead to lithium metal plating,severe side reactions,and safety concerns.The premise to solve these problems is to fully understand the reaction pathways and rate-determining steps of graphite during fast Li^(+)intercalation.Herein,we compare the Li^(+)diffusion through the graphite particle,interface,and electrode,uncover the structure of the lithiated graphite at high current densities,and correlate them with the reaction kinetics and electrochemical performances.It is found that the rate-determining steps are highly dependent on the particle size,interphase property,and electrode configuration.Insufficient Li^(+)diffusion leads to high polarization,incomplete intercalation,and the coexistence of several staging structures.Interfacial Li^(+)diffusion and electrode transportation are the main rate-determining steps if the particle size is less than 10μm.The former is highly dependent on the electrolyte chemistry and can be enhanced by constructing a fluorinated interphase.Our findings enrich the understanding of the graphite structural evolution during rapid Li^(+)intercalation,decipher the bottleneck for the sluggish reaction kinetics,and provide strategic guidelines to boost the fast-charging performance of graphite anode. | Suting Weng Gaojing Yang Simeng Zhang Xiaozhi Liu Xiao Zhang Zepeng Liu Mengyan Cao Mehmet Nurullah Ateş Yejing Li Liquan Chen Zhaoxiang Wang Xuefeng Wang | 2023 | Nano-Micro Letters2023，15，11： | 1 |
| 12 | Morphotropic phase boundary and electrical properties of K1 xNaxNbO3 lead-free ceramics 显示文摘 | Dai Yejing Zhang Xiaowen Chen Kepi | 2009 | Applied Physics Letters2009，94，04： | 1 |
| 13 | A Research for Regional Contribution Rate of Internal Source and External Source of PM_(2.5) Based on Set Pair Analysis Method显示文摘A problem of the air pollution control in China is getting to know a regional contribution rate of internal and external source of PM_(2.5). In this paper,Set Pair Analysis( SPA) method is proposed to calculate the contribution rate of PM_(2.5)in Dongguan City. Due to geographic,meteorological factors and the low concentration of air pollutants in Qingxi area,the PM_(2.5)in this place is mainly contributed by the regional transport of air pollutants from other inside areas of Dongguan,and less affected by the outside of Dongguan. So the concentration of PM_(2.5)in Qingxi area can reflect the Dongguan's basic background concentration of PM_(2.5). On the basis of the basic background concentration,firstly the concentration of each pollutant components is divided into the internal part and the mixed part. Secondly using the source apportionment samples of five monitoring sites in Dongguan we can respectively construct a sample set A and an evaluation set B. Thirdly the SPA is operated onto the mixed part in terms of set B.At last the connection degree between the concentration of each pollutant components and external source and internal source will be calculated,that is the contribution rate. The research reveals that the contribution rate of internal source and external source of PM_(2.5)in Dongguan City is 83%and 17% respectively,which roughly met expectations. This method is simple and effective and it can provide a reference for the government taking reduction measures to control PM_(2.5)pollutants emission. | Zhou Yejing Zhou Jingxuan Xiao Renbin | 2016 | Meteorological and Environmental Research2016，7，2： | 1 |
| 14 | Influ- ence of KOH/Coke mass ratio on properties of activated carbons made by microwave-assisted activation for electric double-layer capacitors 显示文摘 | HE Xiaojun GENG Yejing QIU Jieshan | 2010 | Energy & Fuels2010，24，6： | 1 |
| 15 | Morpho- tropic phase boundary and electrical properties of K1 x NaxNbO3 lead-free ceramics显示文摘 | DAI Yejing ZHANG Xiaowen CHEN Kepi | 2009 | Applied Physics Let- ters2009，94，04： | 1 |
| 16 | Adenovirus-mediated tissue factor pathway inhibitor gene transfer induces apoptosis by blocking the phosphorylation of JAK-2/STAT-3 pathway in vascular smooth muscle cells显示文摘 | Yu Fu Yong Zhao Yue Liu Yejing Zhu Jinyu Chi Jing Hu Xiaohui Zhang Xinhua Yin | 2012 | Cellular Signalling2012，，10： | 1 |
| 17 | Localized-domains staging structure and evolution in lithiated graphite显示文摘Intercalation provides to the host materials a means for controlled variation of many physical/chemical properties and dominates the reactions in metal‐ion batteries.Of particular interest is the graphite intercalation compounds with intriguing staging structures,which however are still unclear,especially in their nanostructure and dynamic transition mechanism.Herein,the nature of the staging structure and evolution of the lithium(Li)‐intercalated graphite was revealed by cryogenic‐transmission electron microscopy and other methods at the nanoscale.The intercalated Li‐ions distribute unevenly,generating local stress and dislocations in the graphitic structure.Each staging compound is found macroscopically ordered but microscopically inhomogeneous,exhibiting a localized‐domains structural model.Our findings uncover the correlation between the long‐range ordered structure and short‐range domains,refresh the insights on the staging structure and transition of Li‐intercalated/deintercalated graphite,and provide effective ways to enhance the reaction kinetic in rechargeable batteries by defect engineering. | Suting Weng Siyuan Wu Zepeng Liu Gaojing Yang Xiaozhi Liu Xiao Zhang Chu Zhang Qiuyan Liu Yao Huang Yejing Li Mehmet NAteş Dong Su Lin Gu Hong Li Liquan Chen Ruijuan Xiao Zhaoxiang Wang Xuefeng Wang | 2023 | Carbon Energy2023，5，1： | 1 |
| 18 | Composition range of morphotropic phase boundary and electrical properties of BNT-BT system显示文摘 | Dai Yejing Pan Jinsong Zhang Xiaowen | 2007 | Key Eng Mater2007，，： | 1 |
| 19 | Preparation of microporous activated carbon and its electrochemical performance for electric double layer capacitor 显示文摘 | HE Xiaojun LEI Jiangwei GENG Yejing | 2009 | Journal of Physics and Chemistry of Solids2009，70，： | 1 |
| 20 | Effects of heavy metals Cd^2+ ,Pb2 + and Zn2+ on DNA damage of loach Misgurnus anguillicaudatus 显示文摘 | ZHANG Yingmei WANG Yejing YU Runliu | 2008 | Fronters of Biology in China2008，3，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员