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| 1 | Predictive value of C-reactive protein/albumin ratio in acute pancreatitis显示文摘BACKGROUND:Serum C-reactive protein(CRP) increases and albumin decreases in patients with inflammation and infection.However,their role in patients with acute pancreatitis is not clear.The present study was to investigate the predictive significance of the CRP/albumin ratio for the prognosis and mortality in acute pancreatitis patients.METHODS:This study was performed retrospectively with 192 acute pancreatitis patients between January 2002 and June 2015.Ranson scores,Atlanta classification and CRP/albumin ratios of the patients were calculated.RESULTS:The CRP/albumin ratio was higher in deceased patients compared to survivors.The CRP/albumin ratio was positively correlated with Ranson score and Atlanta classification in particular and with important prognostic markers such as hospitalization time,CRP and erythrocyte sedimentation rate.In addition to the CRP/albumin ratio,necrotizing pancreatitis type,moderately severe and severe Atlanta classification,and total Ranson score were independent risk factors of mortality.It was found that an increase of 1 unit in the CRP/albumin ratio resulted in an increase of 1.52 times in mortality risk.A prediction value about CRP/albumin ratio >16.28 was found to be a significant marker in predicting mortality with 92.1% sensitivity and 58.0% specificity.It was seen that Ranson and Atlanta classification were higher in patients with CRP/albumin ratio >16.28 compared with those with CRP/albumin ratio ≤16.28.Patients with CRP/albumin ratio >16.28 had a 19.3 times higher chance of death.CONCLUSION:The CRP/albumin ratio is a novel but promising,easy-to-measure,repeatable,non-invasive inflammationbased prognostic score in acute pancreatitis. | Mustafa Kaplan Ihsan Ates Muhammed Yener Akpinar Mahmut Yuksel Ufuk Baris Kuzu Sabite Kacar Orhan Coskun Ertugrul Kayacetin | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，4： | 53 |
| 2 | Rare etiology of mechanical intestinal obstruction: Abdominal cocoon syndrome显示文摘Abdominal cocoon syndrome is a rare cause of intestinal obstruction with unknown etiology. Diagnosis of this syndrome, which can be summarized as the small intestine being surrounded by a fibrous capsule not containing the mesothelium, is difficult in the preoperative period. A 47-year-old male patient was referred to the emergency department with complaints of abdominal pain, nausea, and vomiting for two days. The abdominal computed tomography examination detected dilated small intestinal loops containing air-fluid levels clustered in the left upper quadrant of the abdomen and surrounded by a thick, saclike, contrast-enhanced membrane. During exploratory surgery, a capsular structure was identified in the upper left quadrant with a regular surface that was solid-fibrous in nature. Ab-dominal cocoon syndrome is a rarely seen condition, for which the preoperative diagnosis is difficult. The combination of physical examination and radiological signs, and the knowledge of 'recurrent characteristics of the complaints' that can be learned by a careful history, may be helpful in diagnosis. | Yener Uzunoglu Fatih Altintoprak Omer Yalkin Yasemin Gunduz Guner Cakmak Orhan V Ozkan Fehmi Celebi | 2014 | World Journal of Clinical Cases2014，2，11： | 13 |
| 3 | Intestinal obstruction due to phytobezoars: An update显示文摘The term bezoar refers to an intraluminal mass in the gastrointestinal system caused by the accumulation of indigestible ingested materials, such as vegetables, fruits, and hair. Bezoars are responsible for 0.4%-4% of cases of mechanical intestinal obstruction. The clinical findings of bezoar-induced ileus do not differ from those of mechanical intestinal obstruction due to other causes. The appearance and localization of bezoars can be established with various imaging methods. Treatment of choice depends on the localization of the bezoar which makes the clinical findings. | Enis Dikicier Fatih Altintoprak Orhan Veli Ozkan Orhan Yagmurkaya Mustafa Yener Uzunoglu | 2015 | World Journal of Clinical Cases2015，3，8： | 7 |
| 4 | Arc magmatism as a window to plate kinematics and subduction polarity:Example from the eastern Pontides belt,NE Turkey显示文摘在土耳其的黑海区域的东方 Pontides orogenic 带在 Paleotethys 的闭合期间把一扇批评窗户提供给板 kinematics 和 subduction 极性。这里,我们从这条带在最近的信息上提供简短合成。我们在迟了的白垩纪和新生代弧 magmatism 基于清楚的空间、时间的变化为东方 Pontides orogenic 带和它的联系迟了的 MesozoicCenozoic magmatism 的起源推断向南方的 subduction,和沿着黑海的全部南部的海岸的一个突出的蘸南方的反向的差错系统的存在。我们的模型与赞成的一些最近的建议不符一向北方 subduction 极性,并且在评估与会聚的边缘过程联系的 geodynamic 周围说明弧 magmatism 的重要性。 | Yener Eyuboglu M.Santosh Osman Bektas Seda Ayhan | 2011 | Geoscience Frontiers2011，2，1： | 6 |
| 5 | A systematic review of running-related musculoskeletal injuries in runners显示文摘Objective:Running-related musculoskeletal injuries(RRMIs),especially stemming from overuse,frequently occur in runners.This study aimed to systematically review the literature and determine the incidence and prevalence proportion of RRMIs by anatomic location and specific pathology.Methods:An electronic database search with no date beginning restrictions was performed in SPORTDiscus,PubMed,and MEDLINE up to June 2020.Prospective studies were used to find the anatomic location and the incidence proportion of each RRMI,whereas retrospective or cross-sectional studies were used to find the prevalence proportion of each RRMI.A separate analysis for ultramarathon runners was performed.Results:The overall injury incidence and prevalence were 40.2%±18.8%and 44.6%±18.4%(mean±SD),respectively.The knee,ankle,and lower leg accounted for the highest proportion of injury incidence,whereas the knee,lower leg,and foot/toes had the highest proportion of injury prevalence.Achilles tendinopathy(10.3%),medial tibial stress syndrome(9.4%),patellofemoral pain syndrome(6.3%),plantar fasciitis(6.1%),and ankle sprains(5.8%)accounted for the highest proportion of injury incidence,whereas patellofemoral pain syndrome(16.7%),medial tibial stress syndrome(9.1%),plantar fasciitis(7.9%),iliotibial band syndrome(7.9%),and Achilles tendinopathy(6.6%)had the highest proportion of injury prevalence.The ankle(34.5%),knee(28.1%),and lower leg(12.9%)were the 3 most frequently injured sites among ultramarathoners.Conclusion:The injury incidence proportions by anatomic location between ultramarathoners and non-ultramarathoners were not significantly different(p=0.798).The pathologies with the highest incidence proportion of injuries were anterior compartment tendinopathy(19.4%),patellofemoral pain syndrome(15.8%),and Achilles tendinopathy(13.7%).The interpretation of epidemiological data in RRMIs is limited due to several methodological issues encountered. | Nicolas Kakouris Numan Yener Daniel T.P.Fong | 2021 | Journal of Sport and Health Science2021，10，5： | 5 |
| 6 | Midkine secretion protects Hep3B cells from cadmium induced cellular damage显示文摘AIM: To evaluate role of midkine secretion during Cadmium (Cd) exposure in the human hepatocyte cell line Hep3B cells. METHODS: Different dosages of Cd (0.5-1-5-10 μg/mL) were applied to Hep3B cells and their effects to apoptosis, lactate dehydrogenase (LDH) leakage and midkine secretion were evaluated as time dependent manner. Same experiments were repeated with exogenously applied midkine (250-5000 pg/mL) and/or 5 μg/mL Cd.RESULTS: Cd exposure induced prominent apoptosis and LDH leakage beginning from lower dosages at the 48th h. Cd induced midkine secretion with higher dosages (P < 0.001), (control, Cd 0.5-1-5-10 μg/mL respectively: 1123 ± 73, 1157 ± 63, 1242 ± 90, 1886 ± 175, 1712 ± 166 pg/mL). Exogenous 500-5000 pg/mL midkine application during 5 μg/mL Cd toxicity prevented caspase-3 activation (control, Cd toxicity, 250, 500, 1000, 2500, 5000 pg/mL midkine+ Cd toxicity, respectively: 374 ± 64, 1786 ± 156, 1545 ± 179, 1203 ± 113, 974 ± 116, 646 ± 56, 556 ± 63 cfu) LDH leakage and cell death in Hep3B cells (P < 0.001). CONCLUSION: Our results showed that midkine secretion from Hep3B cells during Cd exposure protects liver cells from Cd induced cellular damage. Midkine has anti-apoptotic and cytoprotective role during Cd toxicity. Further studies are needed to explain the mechanism of midkine secretion and cytoprotective role of midkine during Cd exposure. Midkine may be a promising theurapatic agent in different toxic hepatic diseases. | Nuray Yazihan Haluk Ataoglu Ethem Akcil Burcu Yener Bulent Salman Cengiz Aydin | 2008 | World Journal of Gastroenterology2008，14，1： | 2 |
| 7 | The nature of transition from adakitic to non-adakitic magmatism in a slab window setting:A synthesis from the eastern Pontides,NE Turkey显示文摘东方 Pontides orogenic 带在 AlpineHimalayan 带提供一扇窗户进大陆人弧 magmatism。这条带的迟了的 MesozoicCenozoic geodynamic 进化仍然保持争论。这里,我们在这转变最好被保存的 NE 土耳其在 Gumushane 区域的甘蓝类蔬菜区域从 adakitic 集中于转变的性质到 non-adakitic magmatism。adakitic 岩性学包括斑岩和 hyaloclastites。斑岩被充满黑云母的安山岩,充满角闪石的安山岩和 dacite 代表。hayaloclastites 代表 adakitic 的最后的阶段活动和他们被 adakitic andesitic 岩浆的爆发 / 侵入产生进软碳酸盐泥。non-adakitic 岩性学包括暴烈、联系的 pyroclastic 摇的 basaltic-andesitic。两个岩石组由在学习区域代表新生代 magmatism 的最后的阶段的玄武岩的堤正在切。我们报导 48.71 楨档琠敨 ? 牴湡晳牯敭 ? 湩潴琠楲潧慮? 敳敬楮浵 ? 桷捩 ? 畦瑲敨 ? 獡敳扭敬 ? 污湯 ? 桴 ? 的锆石 U-Pb 年龄 ? 硡獩琠? 潦浲栠硥条湯污爠摯吗? | Yener Eyuboglu M.Santosh Francis O.Dudas Enver Akaryali Sun-Lin Chung Kemal Akdag Osman Bektas | 2013 | Geoscience Frontiers2013，4，4： | 2 |
| 8 | Phase I study on the safety and preliminary efficacy of allogeneic mesenchymal stem cells in hypoxic-ischemic encephalopathy显示文摘BACKGROUND Hypoxic-ischemic encephalopathy(HIE)is a leading cause of morbidity and mortality in the adult as well as in the neonate,with limited options for treatment and significant dysfunctionality.AIM To investigate the safety and preliminary efficacy of allogeneic mesenchymal stem cells(MSCs)in HIE patients.METHODS Patients who had HIE for at least 6 mo along with significant dysfunction and disability were included.All patients were given Wharton’s jelly-derived MSCs at 1×106/kg intrathecally,intravenously,and intramuscularly twice a month for two months.The therapeutic effects and prognostic implications of MSCs were evaluated by multiple follow-ups.Functional independence measure(FIM),modified Ashworth,and Karnofsky scales were used to assess any side effects,neurological and cognitive functions,and overall outcomes.RESULTS The 8 subjects included in the study had a mean age of 33.25±10.18 years.Mean HIE exposure and mean post-HIE durations were 45.63±10.18 and 19.67±29.04 mo,respectively.Mean FIM score was 18.38±1.06,mean modified Ashworth score was 43.5±4.63,and mean Karnofsky score was 20.For the first 24 h,5 of the patients experienced a subfebrile state,accompanied by mild headaches due to intrathecally administration and muscle pain because of intramuscularly administration.Neurological and functional examinations,laboratory tests,electroencephalography,and magnetic resonance imaging were performed to assess safety of treatment.Mean FIM score increased by 20.88±3.31 in the first month(P=0.027)and by 31.38±14.69 in 12 mo(P=0.012).The rate of patients with an FIM score of 126 increased from 14.58%to 16.57%in the first month and 24.90%in 12 mo.CONCLUSION Multiple triple-route Wharton’s jelly-derived MSC administrations were found to be safe for HIE patients,indicating neurological and functional improvement.Based on the findings obtained here,further randomized and placebo research could be performed. | Serdar Kabataş ErdinçCivelek Necati Kaplan Eyüp Can Savrunlu Gülseli Berivan Sezen Mourat Chasan Halil Can Ali Genç Yener Akyuva Osman Boyalı Furkan Diren Erdal Karaoz | 2021 | World Journal of Experimental Medicine2021，11，2： | 2 |
| 9 | Relationship between non-alcoholic fatty liver disease and coronary heart disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is the leading cause of chronic liver disease and considered a liver manifestation of metabolic syndrome.It is in close relationship with insulin resistance,obesity,diabetes mellitus,all of which increase risk of cardiovascular disease(CVD).Besides,many studies point out that NAFLD independently contributes to the development of atherosclerosis and CHD.On the other hand,CVDs are the leading cause of death in NAFLD patients.Many pathophysiological changes and molecular mechanisms play an important role in NAFLD for CVD formation.Atherosclerosis is common in NAFLD,which also mainly contributes to the CVD formation and CHD.Many studies linking atherosclerotic CHD and NAFLD are present in the literature.Subclinical CHD,mainly detected by coronary computed tomography views,have been detected more common in NAFLD patients.Presence of NAFLD has been found to be more common in patients with severe CHD and in stable CHD,NAFLD has been found to be associated with more diffuse disease.In acute coronary syndromes,especially in acute myocardial infarction,patients with NAFLD have been found to have poor prognosis when compared with NAFLD free patients.In this review,our aim is to evaluate the relationship between NAFLD and CHD in detail and go over the pathophysiological mechanisms underlying this relationship. | Ugur Arslan Mustafa Yenerçağ | 2020 | World Journal of Clinical Cases2020，8，20： | 2 |
| 10 | Biomechanical Analysis of Different Techniques in Revision Spinal Instrumentation: Larger Diameter Screws Versus Cement Augmentation显示文摘 | Dirk W. Kiner Christopher D. Wybo William Sterba Yener N. Yeni Stephen W. Bartol Rahul Vaidya | 2008 | Spine2008，，24： | 2 |
| 11 | Erythropoietin attenuates hydrogen peroxide - induced damage of hepatocytes 显示文摘 | Yazihan N Ataoglu H Yener B | 2007 | Turk J Gastroenterol2007，8，4： | 1 |
| 12 | Transceiver optimization for multius- er MIMO systems显示文摘 | Serbetli S Yener A | 2004 | IEEE Transactions on Signal Pro- cessing2004，52，1： | 1 |
| 13 | The effect of sintering temperature on some properties of Cu-SiC composite 显示文摘 | Celebi Ere G Yener T Altinsoy I | 2011 | Journal of Alloys and Compounds2011，，509： | 1 |
| 14 | Self - gripping CovidienTM ProGripTM mesh versus polypropylene, esh in open inguinal hernia repair multicenter short term results 显示文摘 | Yilmaz A Yener O Kaynak B | 2013 | Prague Med Rep2013，114，4： | 1 |
| 15 | Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for application of ascorbyl palmitate 显示文摘 | UNER M WISSING S A YENER G | 2005 | Pharmazie2005，60，8： | 1 |
| 16 | Two-hop secure communication using an untrusted relay显示文摘 | HE X YENER A | 2009 | Eurasip Journal on Wireless Communication and Networking2009，9，30： | 1 |
| 17 | Reduced retinal nerve fiber layer thickness and macular volume in pediatric multiple sclerosis显示文摘 | Yilmaz U Gücüyener K Erin DM | | 0，，12： | 1 |
| 18 | Response surfaces of apricot kernel oil yield in supercritical carbon dioxide显示文摘 | Ozkal S G Yener M E Bayindirli L | 2005 | LWT-Food Science and Technology2005，，38： | 1 |
| 19 | Distributed power allocation strategies for parallel relay networks 显示文摘 | CHEN M SERBETLI S YENER A | 2008 | IEEE Trans on Wireless Communications2008，7，2： | 1 |
| 20 | Cooperation with an untrusted relay: a secrecy perspective显示文摘 | HE X YENER A | 2010 | IEEE Trans Inf Theory2010，56，8： | 1 |
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