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| 1 | The Coix Genome Provides Insights into Panicoideae Evolution and Papery Hull Domestication显示文摘Coix is a grass crop domesticated as early as the Neolithic era.It is still widely cultivated for both highly nutritional food and medicinal use.However,the genetic study and breeding of this crop are hindered by the lack of a sequenced genome.Here,we report de novo sequencing and assembly of the 1619-Mb genome of Coix,and annotation of 75.39%repeats and 39629 protein-coding genes.Comparative genomics analysis showed that Coix is more closely related to sorghum than maize,but intriguingly only Coix and maize had a recent genome duplication event,which was not detected in sorghum.We further constructed a genetic map and mapped several important traits,especially the strength of hull.Selection of papery hull(thin:easy dehulling)from the stony hull(thick:difficult dehulling)in wild progenitors was a key step in Coix domestication.The papery hull makes seed easier to process and germinate.Anatomic and global transcriptome analysis revealed that the papery hull is a result of inhibition of cell division and wall biogenesis.We also successfully demonstrated that seed hull pressure resistance is controlled by two major quantitative trait loci(QTLs),which are associated with hull thickness and color,respectively.The two QTLs were further fine mapped within intervals of 250 kb and 146 kb,respectively.These resources provide a platform for evolutionary studies and will facilitate molecular breeding of this important crop. | Chao Guo Yanan Wang Aiguo Yang Jun He Chaowen Xiao Shanhua Lv Fengming Han Yibing Yuan Yuan Yuan Xiaolong Dong Juan Guo YawenYang-Hailan Liu Ningzhi Zuo Yaxi Hu Kangxu Zhao Zhengbo Jiang Xing Wang Tingting Jiang Yaou Sherf Moju Cao Yuan Wang Zhaobo Long Tingzhao Rong Luqi Huang Shufeng Zhou | 2020 | Molecular Plant2020，13，2： | 11 |
| 2 | Comparison on effect of hydrophobicity on the antibacterial and antifungal activities of α-helical antimicrobial peptides显示文摘HPRP-A1, a 15-mer α-helical cationic peptide, was derived from N-terminus of ribosomal protein L1 (RpL1) of Helicobacter pylori. In this study, HPRP-A1 was used as a framework to obtain a series of peptide analogs with different hydrophobicity by single amino acid substitutions in the center of nonpolar face of the amphipathic helix in order to systematically study the effect of hydrophobicity on biological activities of -helical antimicrobial peptides. Hydrophobicity and net charge of peptides played key roles in the biological activities of these peptide analogs; HPRP-A1 and peptide analogs with relative higher hydrophobicity exerted broad spectrum antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and pathogenic fungi, but also showed stronger hemolytic activity; the change of hydrophobicity and net charge of peptides had similar effects with close trend and extent on antibacterial activities and antifungal activities. This indicated that there were certain correlations between the antibacterial mode of action and the antifungal mode of action of these peptides in this study. The peptides exhibited antimicrobial specificity for bacteria and fungi, which provided potentials to develop new antimicrobial drugs for clinical practices. | ZHAO LianJing HUANG YiBing GAO Song CUI Yan HE Dan WANG Li CHEN YuXin | 2013 | Science China Chemistry2013，56，9： | 3 |
| 3 | Role of helicity of a-helical antimicrobia peptides to improve specificity显示文摘 | Yibing Huang Liyan He Guirong Li Naicui Zhai Hongyu Jiang Yuxin Chen | 2014 | Protein & Cell2014，5，8： | 3 |
| 4 | Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer显示文摘Colorectal cancer is one of the leading causes of cancer death worldwide.According to global genomic status,colorectal cancer can be classified into two main types:microsatellite-stable and microsatellite-instable tumors.Moreover,the two subtypes also exhibit different responses to chemotherapeutic agents through distinctive molecular mechanisms.Recently,mitochondrial DNA depletion has been shown to induce apoptotic resistance in microsatellite-instable colorectal cancer.However,the effects of altered mitochondrial DNA copy number on the progression of microsatellite-stable colorectal cancer,which accounts for the majority of colorectal cancer,remain unclear.In this study,we systematically investigated the functional role of altered mitochondrial DNA copy number in the survival and metastasis of microsatellite-stable colorectal cancer cells.Moreover,the underlying molecular mechanisms were also explored.Our results demonstrated that increased mitochondrial DNA copy number by forced mitochondrial transcription factor A expression significantly facilitated cell proliferation and inhibited apoptosis of microsatellitestable colorectal cancer cells both in vitro and in vivo.Moreover,we demonstrated that increased mitochondrial DNA copy number enhanced the metastasis of microsatellite-stable colorectal cancer cells.Mechanistically,the survival advantage conferred by increased mitochondrial DNA copy number was caused in large part by elevated mitochondrial oxidative phosphorylation.Furthermore,treatment with oligomycin significantly suppressed the survival and metastasis of microsatellite-stable colorectal cancer cells with increased mitochondrial DNA copy number.Our study provides evidence supporting a possible tumor-promoting role for mitochondrial DNA and uncovers the underlying mechanism,which suggests a potential novel therapeutic target for microsatellite-stable colorectal cancer. | Xiacheng Sun Lei Zhan Yibing Chen Gang Wang Linjie He Qian Wang Feng Zhou Fang Yang Jin Wu Yousheng Wu Jinliang Xing Xianli He Qichao Huang | 2018 | Signal Transduction and Targeted Therapy2018，3，1： | 3 |
| 5 | Isoparametric hypersurfaces in Funk spaces显示文摘Funk metrics are a kind of important Finsler metrics with constant negative flag curvature. In this paper, it is proved that any isoparametric hypersurface in Funk spaces has at most two distinct principal curvatures. Moreover, a complete classification of isoparametric families in a Funk space is given. | HE Qun YIN SongTing SHEN YiBing | 2017 | Science China Mathematics2017，60，12： | 3 |
| 6 | A low-impedance transit-time oscillator without foils显示文摘 | Cao Yibing Zhang Jiande He Juntao | 2009 | Physics of Pgasmas2009，16，08： | 1 |
| 7 | Factorization and symplectic uniton numbers for harmonic maps into symplectic groups显示文摘 | HE Qun SHEN Yibing | 2001 | Science in China:Ser A2001，44，： | 1 |
| 8 | A low-impedance transit-time oscillator without foils显示文摘 | Cao Yibing Zhang Jiande He Juntao | 2009 | Phys Plasmas2009，16，08： | 1 |
| 9 | Some results on harmonic maps for Finsler manifolds 显示文摘 | HE Qun SHEN Yibing | 2005 | International Journal of Math2005，，16： | 1 |
| 10 | Protein 3D Structure Comparison Based on LZ Complexity Distance 显示文摘 | BIN LI YIBING LI HONGBO HE | 2007 | High technical communication2007，17，7： | 1 |
| 11 | Titanium carbide and titanium nitride-based nanocomposites as effi- cient catalysts for the Co2+/Co3+ redox couple in dye-sensi- tized solar cells显示文摘 | Jiangjing He Jennifer M Pringle Yibing Cheng | 2014 | Phys Chem C2014，118，16： | 1 |
| 12 | Preparation, thermal and flammability properties of a novel form-stable phase change materials based on high density polyethylene/poly(ethylene-co-vinyl acetate)/organophilic montmorillonite nanocomposites/paraffin compounds 显示文摘 | Cai Yibing Song Lei He Qingliang | 2008 | Energy Conversion and Management2008，49，： | 1 |
| 13 | Selective removal of polycyclic aromatic hydrocarbons (PAHs) from soil washing effluents using biochars produced at different pyrolytic temperatures显示文摘 | Helian Li Ronghui Qu Chao Li Weilin Guo Xuemei Han Fang He Yibing Ma Baoshan Xing | 2014 | Bioresource Technology2014，，： | 1 |
| 14 | Synergistic effect of aluminum hydroxide and expandable graphite on the flame retardancy of polyisocyanurate–polyurethane foams显示文摘 | Wanjin Wang Kui He Quanxiao Dong Ning Zhu Yong Fan Feng Wang Yibing Xia Haifeng Li Jing Wang Zhen Yuan Erpo Wang Zhenfeng Lai Tao Kong Xia Wang Hongwen Ma Mingshu Yang | 2014 | J. Appl. Polym. Sci2014，，4： | 1 |
| 15 | Preparation, thermal and flammability properties of a novel form-stable phase change materials based on high density polyethylene/poly ( ethylene-co-vinyl acetate )/organophilic montmorillonite nanocomposites/paraffin compounds 显示文摘 | Cai Yibing Song Lei He Qingliang | 2008 | Energy Convers Manag2008，49，8： | 1 |
| 16 | A low-impedance transit-time oscillator without foils显示文摘 | Cao Yibing Zhang Jiande He Juntao | 2009 | Physics of Plasmas2009，16，08： | 1 |
| 17 | On the first eigenvalue of Finsler manifolds with nonnegative weighted Ricci curvature显示文摘We prove that for a compact Finsler manifold M with nonnegative weighted Ricci curvature,if its first closed(resp.Neumann)eigenvalue of Finsler-Laplacian attains the sharp lower bound,then M is isometric to a circle(resp.a segment).Moreover,a lower bound of the first eigenvalue of Finsler-Laplacian with Dirichlet boundary condition is also estimated.These generalize the corresponding results in recent literature. | YIN SongTing HE Qun SHEN YiBing | 2014 | Science China Mathematics2014，57，5： | 1 |
| 18 | Improving the room-temperature bendability of Mg-3Al-1Zn alloy sheet by introducing a bimodal microstructure and the texture re-orientation显示文摘A significant enhancement of bendability was achieved by the introduction of bimodal microstructure for AZ31B alloy sheets via pre-compression and subsequent annealing(PCA)process.This combined treatment led to the c-axis of the extracted samples that were inclined by 30°to the rolling direction(30°sample)further shifting toward the rolling direction(RD)and resulting in a higher Schmid factor(SF)value of basal slip under the RD tensile stress.Furthermore,the bimodal microstructure that was introduced by the PCA process broke the damage bands(DBs)in the initial hot rolled AZ31B alloy sheets and gave rise to a more uniform strain distribution in the outer tension region of the bending samples,in which the tensile deformation was accommodated by the equally distributed{101^(-)2}tension twinning and basal slip.Consequently,the bimodal microstructure,shifted basal texture and the modification of DBs were responsible for the significant enhancement in the bendability of the AZ31 alloys. | Chao He Yibing Zhang Ming Yuan Bin Jiang Qinghang Wang Yanfu Chai Guangsheng Huang Dingfei Zhang Fusheng Pan | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，7： | 1 |
| 19 | Design of a dual-frequency high-power microwave generator显示文摘 | He Juntao Cao Yibing Zhang Jiande | 2011 | Laser Part Beams2011，29，4： | 1 |
| 20 | Predicting toxicities of substituted aromatic hydrocarbons to fish by toxicities to Daphnia magna or Photobacterium phosphoreum显示文摘 | Zhao Yuanhui He Yibing Wang Liansheng | 1995 | Toxicological and Environmental Chemistry1995，51，： | 1 |
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