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3篇 您的检索式:作者名="Yingting Zuo"
    题名 作者 年代 出处 被引量
1Low serum albumin levels predict poor outcome in patients with acute ischaemic stroke or transient ischaemic attack显示文摘Background To examine the relationship of serum albumin with poor functional outcome and mortality in patients with acute ischaemic stroke(AIS)or transient ischaemic attack(TIA),and perform a meta-analysis to summarise the association.Methods We analysed data from the Third China National Stroke Registry(CNSR-Ⅲ).Patients were divided into four groups based on serum albumin levels at admission.The outcomes included poor functional outcome(modified Rankin Scale(mRS)score of 3 to 6)and mortality at 3 months and 1 year.Multiple logistic regression models and Cox regression models were used to evaluate the association,respectively.We used a fixed-effect model to calculate the risk ratio for poor functional outcome and a random-effect model for mortality in the meta-analysis.Results A total of 13618 patients were enrolled.During the 3-month follow-up period,compared with 40 to 44.9 g/L group,patients in<35 g/L group had an increased risk of poor functional outcome and mortality(adjusted OR 1.37(95%CI 1.12 to 1.67);adjusted HR 2.13(95%CI 1.41 to 3.23)).The relationship in per 10 g/L decreased serum albumin with prognosis was consistently inversed(adjusted OR 1.17(95%CI 1.01 to 1.35);adjusted HR 1.86(95%CI 1.30 to 2.64)).Also,low serum albumin levels were independently correlated with clinical outcomes at 1 year.In the meta-analysis,the OR for poor functional outcome pooled 3 studies per 1 g/L decrease was 1.03(95%CI 1.02 to 1.05),and the HR for mortality pooled 5 studies was 1.07(95%CI 1.03 to 1.11).Conclusions Low serum albumin levels predict poor functional outcome and mortality in patients with AIS or TIA.Hongyu Zhou Anxin Wang Xia Meng Jinxi Lin Yong Jiang Jing Jing Yingting Zuo Yilong Wang Xingquan Zhao Hao Li Yongjun Wang 2021Stroke & Vascular Neurology2021,6,3:7
2Different contribution of SBP and DBP variability to vascular events in patients with stroke显示文摘Background High blood pressure variability(BPV)is a novel risk factor for cardiovascular disease.However,the heterogeneity of systolic blood pressure variability(SBPV)and diastolic blood pressure variability(DBPV)for different vascular events remains unclear.This study aims to investigate whether SBPV or DBPV has different contribution to vascular events in patients with acute ischaemic stroke(IS)or transient ischaemic attack(TIA).Methods Data from the BOSS(blood pressure and clinical outcome in TIA or IS)study were examined for vascular events at 3-month and 1-year follow-up.BPV was defined as the SD and coefficient of variation(CV)of day-to day measurements within 3 months after IS/TIA.Vascular events include cardiovascular events(myocardial infarction,unstable angina,cardiac death and congestive heart failure)and cerebrovascular events(ischaemic or haemorrhagic stroke).Logistic regression model was used to test the associations between BPV and vascular events.results Of 2325 patients with IS or TIA,103(4.43%)experienced a recurrent stroke and 64(2.75%)had cardiovascular events within 3 months.Day-to day SBPV was only associated with stroke recurrence(BPVSD:OR,1.72,95%CI 1.09 to 2.71;BPVCV:1.86,95%CI 1.19 to 2.92),but not cardiovascular events(BPVSD:1.67,95%CI 0.94 to 2.94;BPVCV:1.51,95%CI 0.86 to 2.64).However,DBPV seems to be related to both stroke(BPVSD:1.60,95%CI 1.02 to 2.49;BPVCV:1.53,95%CI 0.99 to 2.37)and cardiovascular events(BPVSD:2.48,95%CI 1.37 to 4.48;BPVCV:1.92,95%CI 1.09 to 3.36).Similar results were found at 1 year.Conclusions For patients with IS/TIA,stroke recurrence was associated with both SBPV and DBPV;however,cardiovascular events seem to be only related to DBPV.Liye Dai Aichun Cheng Xiwa Hao Jie Xu Yingting Zuo Anxin Wang Xia Meng Hao Li Yilong Wang Xingquan Zhao Yongjun Wang 2020Stroke & Vascular Neurology2020,5,2:6
3CO_(2) combining power and outcomes in patients with acute ischaemic stroke or transient ischaemic attack显示文摘Background and purpose The clinical significance of carbon dioxide combining power(CO_(2) CP)in ischaemic cerebrovascular disease is not well established,and the role of CO_(2) CP in the prognosis of acute ischaemic stroke(AIS)or transient ischaemic attack(TIA)has not been reported.The objective of the study was to investigate the associations between CO2CP and clinical outcomes in patients with AIS or TIA.Methods Data were derived from the China National Stroke Registry III.Patients were classified into five groups by quintiles of CO_(2) CP levels and three groups according to the normal range of CO_(2)CP(23-29 mmol/L).Multivariable Cox and logistic regressions were adopted to explore the associations of CO_(2) CP levels with all-cause death and poor functional outcomes(modified Rankin Scale(mRS)3-6/2-6)at 3 months and 1 year.Results Among 9531 patients included in the study,the median(IQR)CO_(2) CP was 24.9(23.0-27.0)mmol/L.After adjustment for potential confounders,patients in the first CO_(2) CP quintile(21.1-23.3 mmol/L)had higher risk of all-cause death and poor functional outcomes(mRS score of 3-6/2-6)(HR or OR with 95% CI 2.37(1.32 to 4.25),1.49(1.20 to 1.83)and 1.21(1.03 to 1.42),respectively)compared with those in the fourth quintile.Similar results were found for outcomes at 1 year.Furthermore,all associations were also significant when CO_(2) CP was<23 mmol/L compared with CO_(2) CP of 23-29 mmol/L.Conclusions Decreased CO_(2) CP was associated with high risk of all-cause death and poor functional outcomes in patients with AIS or TIA.Anxin Wang Xue Tian Hongqiu Gu Yingting Zuo Xia Meng Wei Lv Hao Li Yongjun Wang 2021Stroke & Vascular Neurology2021,6,2:2
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