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| 1 | Total body irradiation of donors can alter the course of tolerance and induce acute rejection in a spontaneous tolerance rat liver transplantation model显示文摘Liver transplantation is an established therapy for end-stage liver diseases. Graft rejection occurs unless the recipient receives immunosuppression after transplantation. This study aimed to explore the mechanism of acute rejection of liver allografts in rats pre-treated with total body irradiation to eliminate passenger lymphocytes and to define the role of CD4 + CD25 + regulatory T cells in the induction of immunotolerance in the recipient. Male Lewis rats were used as donors and male DA rats were recipients. Rats were randomly assigned to the following four groups: control group, homogeneity liver transplantation group, idio-immunotolerance group and acute rejection group. After transplantation, the survival time of each group, serum alanine aminotransferase, total bilirubin levels, number of Foxp3 + CD4 + CD25 + regulatory T cells, expression of glucocorticoid-induced tumor necrosis factor receptor on T cell subgroups, histopathology of the hepatic graft and spleen cytotoxic T lymphocyte lytic activity were measured. In the acute rejection group, where donors were preconditioned with total body irradiation before liver transplantation, all recipients died between day 17 and day 21. On day 14, serum alanine aminotransferase increased signifi- cantly to (459.2±76.9) U L -1 , total bilirubin increased to (124.1±33.7) μmol L -1 (P<0.05) and the ratio of Foxp3 + CD4 + CD25 + regulatory T cells decreased significantly to 1.50%±0.50% (P<0.05) compared with the other groups. Analysis of the T cell subpopulations in the acute rejection group varied from the other groups. Histological analysis showed typical changes of acute rejection in the acute rejection group only. Preconditioning of the donors with total body irradiation eliminated passenger lymphocytes of the liver graft, and thus affected the course of tolerance and induced acute rejection after liver transplantation. | ZHANG YeWei ZHAO HeWei BO Lin YANG YinXue LU Xiang SUN JingFeng WEN JianFei HE Xia YIN GuoWen | 2012 | Science China(Life Sciences)2012，55，9： | 4 |
| 2 | Energy Efficiency Based on Joint Data Packet Fragmentation and Cooperative Transmission显示文摘Energy efficiency(EE) is a key requirement for the design of short-range communication network.In order to alleviate energy consumption(EC) constraint,a novel layered heterogeneous mobile cloud architecture is proposed in this paper.Based on the proposed layered heterogeneous mobile cloud architecture,we establish an appropriate energy consumption model,and design an energy efficiency scheme based on joint data packet fragmentation and cooperative transmission and analyze the energy efficiency corresponding to different packet sizes and the cloud size.Simulation results show that,when all nodes of the cloud are accessing the same size of data packet fragmentation,the proposed layered heterogeneous mobile cloud architecture can provide significant energy savings.The results provide useful insights into the possible operation of the strategies and show that significant energy consumption reductions are possible. | ZHANG Zufan YI Yinxue YANG Jing JING Xiaorong | 2014 | China Communications2014，11，10： | 3 |
| 3 | Utilizing phase-shifted long-period fiber grating to suppress spectral broadening of a high-power fiber MOPA laser system显示文摘Suppressing nonlinear effects in high-power fiber lasers based on fiber gratings has become a hotspot.At present,research is mainly focused on suppressing stimulated Raman scattering in a high-power fiber laser.However,the suppression of spectral broadening,caused by self-phase modulation or four-wave mixing,is still a challenging attribute to the close distance between the broadened laser and signal laser.If using a traditional fiber grating with only one stopband to suppress the spectral broadening,the signal power will be stripped simultaneously.Confronting this challenge,we propose a novel method based on phase-shifted long-period fiber grating(PS-LPFG)to suppress spectral broadening in a high-power fiber master oscillator power amplifier(MOPA)laser system in this paper.A PS-LPFG is designed and fabricated on 10/130 passive fiber utilizing a point-by-point scanning technique.The resonant wavelength of the fabricated PS-LPFG is 1080 nm,the full width at half maximum of the passband is 5.48 nm,and stopband extinction exceeds 90%.To evaluate the performance of the PS-LPFG,the grating is inserted into the seed of a kilowattlevel continuous-wave MOPA system.Experiment results show that the 30 dB linewidth of the output spectrum is narrowed by approximately 37.97%,providing an effective and flexible way for optimizing the output linewidth of highpower fiber MOPA laser systems. | Yinxu Bian Kerong Jiao Xuecheng Wu Hua Shen Feiyan Yang Rihong Zhu | 2021 | High Power Laser Science and Engineering2021，9，3： | 2 |
| 4 | Character- ization of placenta - derived mesenchymal stem cells cultured in autologous human cord blood serum 显示文摘 | Libin Wang Yinxue Yang Yon~hao Zhu | 2012 | Molecular Medicine Ile- ports2012，6，4： | 1 |
| 5 | High performance removal of sulfamethoxazole using large specific area of biochar derived from corncob xylose residue显示文摘To remove antibiotics from waste water,an alkali active porous biochar,850BC,was prepared from corncob xylose residue.In preparation,NaOH dipping was used for silicon removal and KOH activation was operated at 850℃.Further characterization containing BET,SEM,and FTIR were confirmed.850BC possessed a huge specific surface area of 3043 m^(2)·g^(−1),developed pore structure and abundant oxygen functional groups.The adsorption performance of sulfamethoxazole on 850BC was quick and efficient,and the adsorption capacity reached 1429 mg·g^(−1),which was significantly higher than other adsorbents reported previously.While pseudo-second-order kinetic model and Langmuir model could better describe the adsorption,chemisorp-tion dominated the SMX adsorption onto 850BC.In virtue of pore-filling andπ-πinteraction as major mechanism,a large surface area and rich oxygen-containing functional groups led to an excellent adsorption performance.Thus,this preparation method provided a biochar-based adsorbent with enhanced specific surface for efficient removal of antibiotic pollutants. | Yinxue Li Hongru Shang Yongna Cao Chunhui Yang Yujie Feng Yanling Yu | 2022 | Biochar2022，4，1： | 1 |
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