5篇
您的检索式：作者名="Yoav Smith"
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| 1 | Defining a prognostic marker panel for patients with ovarian serous carcinoma effusions显示文摘 | Ben Davidson Yoav Smith Jahn M. Nesland Janne K?rn Reuven Reich Claes G. Tropè | 2013 | Human Pathology2013，，： | 1 |
| 2 | Similarity measurement method for the classification of architecturally differentiated images显示文摘 | Smith Yoav Gershom Zajicek Micheal Werman | 1999 | Computer and Biomedical Research1999，32，1： | 1 |
| 3 | Association Between C-Reactive Protein Genotype, Circulating Levels, and Aortic Pulse Wave Velocity显示文摘 | Wiebke Schumacher John Cockcroft Nicholas J. Timpson Carmel M. McEniery John Gallacher Ann Rumley Gordon Lowe George Davey Smith Ian B. Wilkinson Yoav Ben-Shlomo | 2009 | Hypertension2009，，2： | 1 |
| 4 | 6年以上婚姻质量的变化与男性心血管疾病危险因素的关系:结果来自英国的埃文父母与儿童纵向前瞻性队列研究显示文摘背景婚姻关系的质量被认为是对心血管健康结果的独立影响因子。这项研究调查了婚姻关系质量的变化与男性心血管疾病(CVD)危险因素之间的关系。 | Ian Bennett-Britton Alison Teyhan John Macleod Naveed Sattar George Davey Smith Yoav Ben-Shlomo 曹勤 范竹萍 | 2018 | 英国医学杂志中文版2018，21，2： | 0 |
| 5 | Pleiotropic tumor suppressor functions of WWOX antagonize metastasis显示文摘Tumor progression and metastasis are the major causes of death among cancer associated mortality.Metastatic cells acquire features of migration and invasion and usually undergo epithelia-mesenchymal transition(EMT).Acquirement of these various hallmarks rely on different cellular pathways,including TGF-βand Wnt signaling.Recently,we reported that WW domain-containing oxidoreductase(WWOX)acts as a tumor suppressor and has anti-metastatic activities involving regulation of several key microRNAs(miRNAs)in triple-negative breast cancer(TNBC).Here,we report that WWOX restoration in highly metastatic MDA-MB435S cancer cells alters mRNA expression profiles;further,WWOX interacts with various proteins to exert its tumor suppressor function.Careful alignment and analysis of gene and miRNA expression in these cells revealed profound changes in cellular pathways mediating adhesion,invasion and motility.We further demonstrate that WWOX,through regulation of miR-146a levels,regulates SMAD3,which is a member of the TGF-βsignaling pathway.Moreover,proteomic analysis of WWOX partners revealed regulation of the Wnt-signaling activation through physical interaction with Disheveled.Altogether,these findings underscore a significant role for WWOX in antagonizing metastasis,further highlighting its role and therapeutic potential in suppressing tumor progression. | Saleh Khawaled Giovanni Nigita Rosario Distefano Sara Oster Sung-Suk Suh Yoav Smith Abed Khalaileh Yong Peng Carlo M.Croce Tamar Geiger Victoria L.Seewaldt Rami I.Aqeilan | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
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