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1篇 您的检索式:作者名="Yongchao C.Ma"
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1RNA methylation preserves ES cell identity by chromatin silencing of retrotransposons显示文摘RNA methylation on N6-methyladenosine(m6A)and histone methylation are critical mechanisms regulating gene expression at epitranscriptomic and epigenetic levels,respectively.However,how RNA methylation modulates histone methylation,and in which biological processes,is unknown.In a recent study published in Nature,Liu et al.1 identified the critical roles of m6A and its reader YTHDC1 in mediating histone methylation and chromatin silencing of retrotransposon genes to preserve embryonic stem(ES)cell identity.Zhaofa Xu Annabel Ma Yongchao C.Ma 2021Signal Transduction and Targeted Therapy2021,6,8:0
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