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| 1 | 3-D CFD analysis of relative humidity distribution in greenhouse with a fog cooling system and refrigerative dehumidifers显示文摘 | Kim Keesung Yoona Jeongyeol Kwon Hyuckjin | 2008 | Biosystems Engineering2008，100，： | 1 |
| 2 | Metronidazole - induced encephalopathy显示文摘 | Dong Wook Kim Jong - Moo Park Byung - Woo Yoona | 2004 | J Neurol Sci2004，224，： | 1 |
| 3 | NADPH oxidase is a novel target of delphinidin for the inhibition of UVB ‐induced MMP ‐1 expression in human dermal fibroblasts显示文摘 | Tae‐Gyu Lim Sung Keun Jung Jong‐eun Kim Yoona Kim Hyong Joo Lee Tae Su Jang Ki Won Lee | 2013 | Exp Dermatol2013，，6： | 1 |
| 4 | 4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions显示文摘Many approaches to neurodegenerative diseases that focus on amyloid-βclearance and gene therapy have not been successful.Some therapeutic applications focus on enhancing neuronal cell survival during the pathogenesis of neurodegenerative diseases,including mitochondrial dysfunction.Plasma membrane(PM)redox enzymes are crucial in maintaining cellular physiology and redox homeostasis in response to mitochondrial dysfunction.Neurohormetic phytochemicals are known to induce the expression of detoxifying enzymes under stress conditions.In this study,mechanisms of neuroprotective effects of 4-hydroxycinnamic acid(HCA)were examined by analyzing cell survival,levels of abnormal proteins,and mitochondrial functions in two different neuronal cells.HCA protected two neuronal cells exhibited high expression of PM redox enzymes and the consequent increase in the NAD^(+)/NADH ratio.Cells cultured with HCA showed delayed apoptosis and decreased oxidative/nitrative damage accompanied by decreased ROS production in the mitochondria.HCA increased the mitochondrial complexes I and II activities and ATP production.Also,HCA increased mitochondrial fusion and decreased mitochondrial fission.Overall,HCA maintains redox homeostasis and energy metabolism under oxidative/metabolic stress conditions.These findings suggest that HCA could be a promising therapeutic approach for neurodegenerative diseases. | Sujin Park YoonA Kim Jaewang Lee Hyunsoo Seo Sang-Jip Nam Dong-Gyu Jo Dong-Hoon Hyun | 2023 | Food Science and Human Wellness2023，12，4： | 0 |
| 5 | Anti-inflammatory Effects of Ampelopsis Japonica Root on Contact Dermatitis in Mice显示文摘Objective:To investigate the anti-inflammatory potential of Ampelopsis japonica on contact dermatitis(CD).Methods:A total of 38 Balb/c mice were divided into 5 groups by using a random number table:normal mice(n=6),CID model mice(n=8),CD mice treated with 3 or 30 mg/kg of the ethanol extract of A.japonica(EEAJ,n=8)and 7.5 mg/kg dexamethasone treated CD mice(DEX,n=8).CD was induced using topical application of 1-fluoro-2,4-dinitrofluorobenzene in mice.EEAJ and DEX were topically applied to the shaved skin of each mouse for 6 days,and the effects of EEAJ and DEX on skin lesions and color,histopathological abnormalities such as epidermal hyperplasia and immune cell infiltration,and tumor necrosis factor(TNF)-α,interleukin-6(IL-6),and monocyte chemoattractant protein-1(MCP-1)production were investigated.The effects on changes in body weights and spleen/body weight ratio were also investigated.Results:EEAJ at 30 mg/kg significantly prevented scaling,erythema and enlargement of skin weight compared to using carbon dioxide.EEAJ also prevented epithelial hyperplasia and immune cell infiltrations induced by repeated application of DNFB(P<0.01).In addition,EEAJ significantly lowered levels of TNF-α,IL-6 and MCP-1(P<0.05 or P<0.01).The anti-inflammatory effects of EEAJ were similar to those of DEX.Conclusion:A.japonica may be a new therapeutic agent with the potential to reduce or replace corticosteroids and its mechanisms are closely related to regulation of TNF-α production. | Yoona Oh Hongbum Lee Beodeul Yang Sura Kim Hyunwoo Jeong Hyungwoo Kim | 2022 | Chinese Journal of Integrative Medicine2022，28，8： | 0 |
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