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| 1 | Endoscopic removal of gastric ectopic pancreas:An initial experience with endoscopic submucosal dissection显示文摘AIM:To evaluate the therapeutic usefulness and safety of endoscopic resection in patients with gastric ectopic pancreas.METHODS:A total of eight patients with ectopic pancreas were included.All of them underwent endoscopic ultrasonography before endoscopic resection.Endo-scopic resection was performed by two methods:endo-scopic mucosal resection(EMR)by the injection-and-cut technique or endoscopic mucosal dissection(ESD).RESULTS:We planned to perform EMR in all eight cases but EMR was successful in only four cases.In the other four cases,saline spread into surrounding normal tissues and the lesions becameattened,which made it impossible to remove them by EMR.Inthose four cases,we performed ESD and removed the lesions without any complications.CONCLUSION:If conventional EMR is difficult to remove gastric ectopic pancreas,ESD is a feasible alternative method for successful removal. | Dong Yup Ryu Gwang Ha Kim Do Youn Park Bong Eun Lee Jae Hoon Cheong Dong Uk Kim Hyun Young Woo Jeong Heo Geun Am Song | 2010 | World Journal of Gastroenterology2010，16，36： | 24 |
| 2 | Clinicopathologic factors influencing the accuracy of EUS for superficial esophageal carcinoma显示文摘AIM:To identify clinicopathologic factors influencing the accuracy of a high-frequency catheter probe endoscopic ultrasonography(EUS)for superficial esophageal carcinomas(SECs).METHODS:A total of 126 patients with endoscopically suspected SEC,who underwent EUS and curative treatment at Pusan National University Hospital during2005-2013,were enrolled.We reviewed the medical records of the 126 patients and compared EUS findings with histopathologic results according to clinicopathologic factors.RESULTS:A total of 114 lesions in 113 patients were included in the final analysis.The EUS assessment of tumor invasion depth was accurate in 78.9%(90/114)patients.Accuracy did not differ according to histologic type,tumor differentiation,tumor location,or macroscopic shape.However,accuracy significantly decreased for tumors≥3 cm in size(P=0.002).Overestimation and underestimation of the invasion depth occurred for 11(9.6%)and 13 lesions(11.4%),respectively.In multivariate analyses,tumor size≥3 cm was the only factor significantly associated with EUS accuracy(P=0.031),and was specifically associated with the underestimation of invasion depth.CONCLUSION:EUS using a high-frequency catheter probe generally provides highly accurate assessments of SEC invasion depth,but its accuracy decreases for tumors≥3 cm. | Jung Im Jung Gwang Ha Kim Hoseok I Do Youn Park Tae Kyun Kim Young Hwa Cho Yong Wan Sung Mun Ki Choi Bong Eun Lee Geun Am Song | 2014 | World Journal of Gastroenterology2014，20，20： | 9 |
| 3 | Significant risk and associated factors of active tuberculosis infection in Korean patients with inflammatory bowel disease using anti-TNF agents显示文摘AIM:To evaluate the incidence and risk factors of Korean tuberculosis(TB) infection in patients with inflammatory bowel disease(IBD) undergoing anti-TNF treatment.METHODS:The data of IBD patients treated with anti-TNFs in 13 tertiary referral hospitals located in the southeastern region of Korea were collected retrospectively.They failed to show response or were intolerant to conventional treatments,including steroids or immunomodulators.Screening measures for latent TB infection(LTBI)and the incidence and risk factors ofactive TB infection after treatment with anti-TNFs were identified.RESULTS:Overall,376 IBD patients treated with antiTNF agents were recruited(male 255,mean age of anti-TNF therapy 32.5±13.0 years);277 had Crohn’s disease,99 had ulcerative colitis,294 used infliximab,and 82 used adalimumab.Before anti-TNF treatment,screening tests for LTBI including an interferon gamma release assay or a tuberculin skin test were performed in 82.2%of patients.Thirty patients(8%)had LTBI.Sixteen cases of active TB infection including one TB-related mortality occurred during 801 personyears(PY)follow-up(1997.4 cases per 100000 PY)after anti-TNF treatment.LTBI(OR=5.76,95%CI:1.57-21.20,P=0.008)and WBC count<5000 mm3(OR=4.5,95%CI:1.51-13.44,P=0.007)during follow-up were identified as independently associated risk factors.CONCLUSION:Anti-TNFs significantly increase the risk of TB infection in Korean patients with IBD.The considerable burden of TB and marked immunosuppression might be attributed to this risk. | Eun Soo Kim Geun Am Song Kwang Bum Cho Kyung Sik Park Kyeong Ok Kim Byung Ik Jang Eun Young Kim Seong Woo Jeon Hyun Seok Lee Chang Heon Yang Yong Kook Lee Dong Wook Lee Sung Kook Kim Tae Oh Kim Jonghun Lee Hyung Wook Kim Sam Ryong Jee Seun Ja Park Hyun Jin Kim | 2015 | World Journal of Gastroenterology2015，21，11： | 5 |
| 4 | Advantages of using the CRISPR/Cas9 system of genome editing to investigate male reproductive mechanisms using mouse models显示文摘基因混乱技术长为男繁殖生物学的学习是有益的。因为包含的时间和费用,除了在专家实验室,然而,这种技术不是一个可行方法。基因混乱的 CRISPR/Cas9 系统的来临迎来了基因调查的一个新时代。现在,在很小的时间并且以很小的成本产生破坏基因的老鼠模型是可能的。这篇热点文章讨论这种技术的应用程序在一些能被用来揭示男繁殖机制的必要、非本质的基因部件的这个系统的未来使用学习男富饶和外表的遗传。 | Samantha AM Young R John Aitken Masahito Ikawa | 2015 | Asian Journal of Andrology2015，17，4： | 4 |
| 5 | Acute distal common bile duct angle is risk factor for postendoscopic retrograde cholangiopancreatography pancreatitis in beginner endoscopist显示文摘BACKGROUND Post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis(PEP)is a critical and poorly managed complication of ERCP.Endoscopists need to understand the risk factors for PEP.However,the majority of studies investigating ERCP-related risk factors have included well-trained endoscopists,with the issue of endoscopist experience on PEP incidence not having been systematically evaluated.AIM To explore the risk factors for PEP in beginner endoscopists without supervision.METHODS We performed a retrospective analysis of 293 patients,with naïve papilla and no history of pancreatitis,treated using bile duct cannulation.Patients were classified according to the endoscopist’s experience(beginner vs expert).The angle of the distal common bile duct(CBD)was measured as the angle between the lower wall of the bile duct and a vertical line extending to the lower wall of the bile duct on coronal view computed tomography.RESULTS After propensity matching,there were no differences between patients treated by the expert and beginner endoscopist with regard to age,sex,mean bile duct dilatation,and ratio of benign disease.The distal CBD angle was classified as acute(>30º)or obtuse(≤30º),based on the mean angle of 29.9ºfor the group.An acute distal CBD angle was a significant risk factor for PEP for beginner(P=0.049),but not expert.CONCLUSION For beginner endoscopists first performing unsupervised ERCP,cases with an obtuse distal CBD angle may be more appropriate to lower the risk of PEP. | Sung Yong Han Dong Uk Kim Moon Won Lee Young Joo Park Dong Hoon Baek Gwang Ha Kim Geun Am Song | 2020 | World Journal of Clinical Cases2020，8，1： | 3 |
| 6 | B-type natriuretic peptide exerts broad functional opposition to transforming growth factor beta in primary human cardiac frbroblasts: fi- brosis,myofibroblast conversion,proliferation, and inflamma- tion显示文摘 | Kapoun AM Liang F ()'Young G | 2004 | Circ Res2004，94，4： | 1 |
| 7 | Reversal of adriamycin resistance by verapamil in human ovarian cancer显示文摘 | Hamilton TC Young RC | 1984 | Science1984，224，4652： | 1 |
| 8 | B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts : fibrosis, myoflbroblast conversion, proliferation, and inflammation显示文摘 | Kapoun AM Liang F O'Young G | 2004 | Circ Res2004，94，4： | 1 |
| 9 | Improved resuscitation minimizes respiratory dysfunction and blunts interleukin - 6 and nuclear factor - kappa B activation after traumatic hemorrhage 显示文摘 | Claridge JA Schulman AM Young JS | 2002 | Crit Care Med2002，30，8： | 1 |
| 10 | Functional opposition to transforming growth factor-β in primary human cardiac fibroblasts:fibrosis,myofibroblast conversion,proliferation,and inflammation显示文摘 | Kapoun AM Faquan L O'Young G | 2004 | Circ Res2004，94，4： | 1 |
| 11 | B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibrobtasts: fibrosis, myofibroblast conver- sion, proliferation, and inflammation 显示文摘 | Kapoun AM Liang F O'Young G | 2004 | Circ Res2004，94，4： | 1 |
| 12 | Impact of Breast Pumping on Lactogenesis Stage Ⅱ After Cesarean Delivery: A Randomized Clinical TriM显示文摘 | Chapman DJ Young S Ferris AM | 2001 | Pediatrics2001，107，6： | 1 |
| 13 | Lipid peroxidation induced in vivo by hyperhomocysteinemia in pigs显示文摘 | Young PB Kennedy S Molloy AM | 1997 | Atherosclerosis1997，129，1： | 1 |
| 14 | B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts:fibrosis,myofibroblast conversion,proliferation,and inflammation显示文摘 | Kapoun AM Liang F O' Young G | 2004 | Circ Res2004，94，4： | 1 |
| 15 | Computed tomography of desmoid tumors of bone : desmoplastic fibroma显示文摘 | Young JW Aisner SC Levine AM | 1998 | Skeletal Radiol1998，17，5： | 1 |
| 16 | B-type natriureticpeptide exerts broad functional opposition to transforminggrowth factor-βin primary human cardiac fibroblasts:fibrosis,myofibroblast conversion,proliferation,and inflammation显示文摘 | Kapoun AM Liang F O′Young G | 2004 | Criculation Research2004，94，17： | 1 |
| 17 | Rosuvastatin,a new HMG-CoA reductase inhibitor,protects ischemic reperfused myocardium in normocholesterolemic rats显示文摘 | Ikeda Y Young LH Lefer AM | 2003 | J Cardiovasc Pharmacol2003，41，： | 1 |
| 18 | Aberrant NF-κB expression in autism spectrum condition:a mechanism for neuroinflammation显示文摘 | Young AM Campbell E Lynch S | 2011 | Frontiers in Psychiatry2011，2，27： | 1 |
| 19 | FTIR investigation of monomer polymerisation and polyacid neutralisation kinetics and mechanisms in various aesthetic dental restorative materials显示文摘 | Young AM Rafeeka SA Howlett JA | 2004 | Biomaterials2004，25，5： | 1 |
| 20 | B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts:fibrosis,myofibroblast conversion,proliferation,and inflammation显示文摘 | Kapoun AM Liang F O'Young G | 2004 | Circ Res2004，94，4： | 1 |
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