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| 1 | Micro RNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling显示文摘Liver fibrosis is a repair process in response to damage in the liver; however, severe and chronic injury promotes the accumulation of fibrous matrix, destroying the normal functions and architecture of liver. Hepatic stellate cells(HSCs) are quiescent in normal livers, but in damaged livers, they transdifferentiate into myofibroblastic HSCs, which produce extracellular matrix proteins. Hedgehog(Hh) signaling orchestrates tissue reconstruction in damaged livers and contributes to liver fibrogenesis by regulating HSC activation. Micro RNAs(mi RNAs), endogenous small non-coding RNAs interfering with RNA post-transcriptionally, regulate various cellular processes in healthy organisms. The dysregulation of mi RNAs is closely associated with diseases, including liver diseases. Thus, mi RNAs are good targets in the diagnosis and treatment of various diseases, including liver fibrosis; however, the regulatory mechanisms of mi RNAs that interact with Hh signaling in liver fibrosis remain unclear. We review growing evidence showing the association of mi RNAs with Hh signaling. Recent studies suggest that Hh-regulating mi RNAs induce inactivation of HSCs, leading to decreased hepatic fibrosis. Although mi RNAdelivery systems and further knowledge of interacting mi RNAs with Hh signaling need to be improved for the clinical usage of mi RNAs, recent findings indicate that the mi RNAs regulating Hh signaling are promising therapeutic agents for treating liver fibrosis. | Jeongeun Hyun Youngmi Jung | 2016 | World Journal of Gastroenterology2016，22，29： | 8 |
| 2 | Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans显示文摘 | Omenetti Alessia Porrello Alessandro Jung Youngmi Yang Liu Popov Yury Choi Steve S Witek Rafal P Alpini Gianfranco Venter Juliet Vandongen Hendrika M Syn Wing-Kin Baroni Gianluca Svegliati Benedetti Antonio Schuppan Detlef Diehl Anna Mae | 2008 | Journal of Clinical Investigation2008，，10： | 3 |
| 3 | Hedgehog-Mediated Epithelial-to-Mesenchymal Transition and Fibrogenic Repair in Nonalcoholic Fatty Liver Disease显示文摘 | Wing–Kin Syn Youngmi Jung Alessia Omenetti Manal Abdelmalek Cynthia D. Guy Liu Yang Jiangbo Wang Rafal P. Witek Caitlin M. Fearing Thiago A. Pereira Vanessa Teaberry Steve S. Choi J. Conde–Vancells Gamze F. Karaca Anna Mae Diehl | 2009 | Gastroenterology2009，，4： | 2 |
| 4 | Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice显示文摘 | Bego?a Ochoa Wing‐Kin Syn Igotz Delgado Gamze F. Karaca Youngmi Jung Jiangbo Wang Ana M. Zubiaga Olatz Fresnedo Alessia Omenetti Marzena Zdanowicz Steve S. Choi Anna Mae Diehl | 2010 | Hepatology2010，，： | 2 |
| 5 | Bone Marrow–Derived Hepatic Oval Cells Differentiate Into Hepatocytes in 2-Acetylaminofluorene/Partial Hepatectomy–Induced Liver Regeneration显示文摘 | Seh–Hoon Oh Rafal P. Witek Si–Hyun Bae Donghang Zheng Youngmi Jung Anna C. Piscaglia Bryon E. Petersen | 2007 | Gastroenterology2007，，： | 1 |
| 6 | Composition of corn dry-grind ethanol by-products: DDGS, wet cake, and thin stillage显示文摘 | Youngmi Kim Nathan S. Mosier Rick Hendrickson Thaddeus Ezeji Hans Blaschek Bruce Dien Michael Cotta Bruce Dale Michael R. Ladisch | 2007 | Bioresource Technology2007，，： | 1 |
| 7 | Inhibitory mechanism of anti-allergic peptides in RBL2H3 cells显示文摘 | Kyungjong Kim a Youngmi Kim a Hae Yeong Kim | 2008 | European Journal of Pharmacology2008，581，： | 1 |
| 8 | Jacaranoneand Related Compounds from the Fresh Fruits of Ternstroemiajaponica and their Antioxidative Activity显示文摘 | Youngmi Jo Jiyoung Suh Myoung Hee Shin | 2005 | Arch pharm Res2005，28，8： | 1 |
| 9 | Regional model of EKC for air pollution : evidence from the republic of Korea显示文摘 | Soonae P Youngmi L | 2011 | Energy Policy2011，39，： | 1 |
| 10 | IL‐17 mediates estrogen‐deficient osteoporosis in an Act1‐dependent manner显示文摘 | Carl J. DeSelm Yoshifumi Takahata Julia Warren Jean C. Chappel Taimur Khan Xiaoxia Li Caini Liu Yongwon Choi Youngmi Faith Kim Wei Zou Steven L. Teitelbaum | 2012 | J. Cell. Biochem2012，，： | 1 |
| 11 | Testing a theoreti cal model predict uncertainty and depression in patients undergoing renal replacement therapy in Korea显示文摘 | Heeyoung L Karen G S Youngmi J | 2008 | Asian Nurs Res2008，2，2： | 1 |
| 12 | The eco-friendly surface modification of textiles for deep digital textile printing by in-line atmospheric non-thermal plasma treatment显示文摘 | YOUNGMI Park KANG Koo | 2014 | Fibers and Polymers2014，15，8： | 1 |
| 13 | Survey of Klebsiella pneumoniae strains producing extended-spectrum β-lactamases: prevalence of SHV-12 and SHV-2a in Korea显示文摘 | Jungmin K Youngmi K Hyunjoo P | 1998 | J Clin Microbiol1998，36，5： | 1 |
| 14 | Deactivation of cellulases by phenols显示文摘 | Eduardo Ximenes Youngmi Kim Nathan Mosier Bruce Dien Michael Ladisch | 2010 | Enzyme and Microbial Technology2010，，1： | 1 |
| 15 | Field emission of carbon nanotubes and electronic structure of carbon nanopeapods显示文摘 | Kim Gunn Son Young-Woo Cho Youngmi | 2002 | Current Applied Physics2002，2，1： | 1 |
| 16 | Are the adverse effects of body position in patients with obstructive sleep apnea dependent 显示文摘 | Jeffery MM Youngmi C Abid B | 2010 | Sleep Breath2010，14，： | 1 |
| 17 | Interleukin-1 induces the production of vascular endothelial growth factor (VEGF) in rheumatoid arthritis synovial fibroblasts via AP-1-dependent pathways显示文摘 | Mi-La C Young Ok J YoungMi | 2006 | Immunol Lett2006，103，： | 1 |
| 18 | Wearing comfort of temperature-adaptable textiles by dual-phase coatings between phase-change materials and silicon carbide particles显示文摘 | Youngmi Park Eunae Kim | | 0，，： | 1 |
| 19 | Charge sensitive and incentive compatible end-to-end window-based control for selfish users 显示文摘 | Jin Youngmi and Kesidis G | 2006 | IEEE Journal on Selected Area in Communications2006，24，5： | 1 |
| 20 | Evaluation of TYLCV-resistant tomato germplasm using molecular markers显示文摘 | KWANGHWAN K YOUNGMI C HAKSOON C | | 0，，01： | 1 |
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