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4篇 您的检索式:作者名="Yuemei Sun"
    题名 作者 年代 出处 被引量
1Introduction of exogenous DNA into cotton via the pollen-tube pathway with GFP as a reporter显示文摘The green fluorescent protein (GFP) gene from the jellyfish Aequorea victoria as a vital reporter for gene expression in plants is considered to have several advantages over other reporter genes. The pBIN35S-mGFP4 plasmid DNA has been introduced into cotton embryos by the pollen-tube pathway method. A transformed seedling has been verified according to its GFP-related fluorescence and Southern blotting analysis. The results provided direct and convincing facts in cytology and molecular biology for the pollen-tube pathway method, an efficient transformation technique used in plants.Guocun Huang Yuemei Dong Jingsan Sun 1999Chinese Science Bulletin1999,44,8:6
2HER2/neu expression correlates with vasculogenic mimicry in invasive breast carcinoma显示文摘Tieju Liu Baocun Sun Xiulan Zhao Qiang Gu Xueyi Dong Zhi Yao Nan Zhao Jiadong Chi Ning Liu Ran Sun Yuemei Ma 2012J. Cell. Mol. Med2012,,1:1
3Seasonal distribution of inhaled allergens in allergic asthma patients with or without allergic rhinitis显示文摘To the Editor:Allergic asthma and allergic rhinitis(AR)are common diseases that often occur concomitantly.Approximately 80%of allergic asthmas suffer from AR symptoms,as the two diseases share common immunopathological mechanisms.Sensitizationand exposure to allergens are the risk factors that induce and aggravate allergic airway diseases such as allergic asthma and AR.Ruxian Tian Yujuan Yang Liping Liu Yuemei Sun Ningbo Tang Yu Zhang Nan Zhang Xicheng Song Claus Bachert 2022Chinese Medical Journal2022,,15:0
4Paradoxical effects of DNA tumor virus oncogenes on epithelium-derived tumor cell fate during tumor progression and chemotherapy response显示文摘Epstein-Barr virus(EBV)and human papillomavirus(HPV)infection is the risk factors for nasopharyngeal carcinoma and cervical carcinoma,respectively.However,clinical analyses demonstrate that EBV or HPV is associated with improved response of patients,although underlying mechanism remains unclear.Here,we reported that the oncoproteins of DNA viruses,such as LMP1 of EBV and E7 of HPV,inhibit PERK activity in cancer cells via the interaction of the viral oncoproteins with PERK through a conserved motif.Inhibition of PERK led to increased level of reactive oxygen species(ROS)that promoted tumor and enhanced the efficacy of chemotherapy in vivo.Consistently,disruption of viral oncoprotein-PERK interactions attenuated tumor growth and chemotherapy in both cancer cells and tumor-bearing mouse models.Our findings uncovered a paradoxical effect of DNA tumor virus oncoproteins on tumors and highlighted that targeting PERK might be an attractive strategy for the treatment of NPC and cervical carcinoma.Jiang He Liyu Liu Feiyu Tang You Zhou Huan Liu Can Lu Deyun Feng Hong Zhu Yitao Mao Zhi Li Lu Zhang Yuemei Duan Zhi Xiao Musheng Zeng Liang Weng Lun-Quan Sun 2021Signal Transduction and Targeted Therapy2021,6,12:0
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