维普中文期刊产品整合服务
39篇 您的检索式:作者名="Zaid H"
    题名 作者 年代 出处 被引量
1Efficacy and safety of anti-hepatic fibrosis drugs显示文摘Recent progress in our understanding of the pathways linked to progression from hepatic insult to cirrhosis has led to numerous novel therapies being investigated as potential cures and inhibitors of hepatic fibrogenesis. Liver cirrhosis is the final result of prolonged fibrosis, which is an intimate balance between fibrogenesis and fibrinolysis. A number of these complex mechanisms are shared across the various etiologies of liver disease. Thankfully, investigation has yielded some promising results in regard to reversal of fibrosis, particularly the indirect benefits associated with antiviral therapy for the treatment of hepatitis B and C and the farnesoid receptor agonist for the treatment of primary biliary cholangitis and metabolic associated fatty liver disease. A majority of current clinical research is focused on targeting metabolic associated fatty liver disease and its progression to metabolic steatohepatitis and ultimately cirrhosis, with some hope of potential standardized therapeutics in the near future. With our ever-evolving understanding of the underlying pathophysiology, these therapeutics focus on either controlling the primary disease(the initial trigger of fibrogenesis), interrupting receptor ligand interactions and other intracellular communications, inhibiting fibrogenesis, or even promoting resolution of fibrosis. It is imperative to thoroughly test these potential therapies with the rigorous standards of clinical therapeutic trials in order to ensure the highest standards of patient safety. In this article we will briefly review the key pathophysiological pathways that lead to liver fibrosis and present current clinical and experimental evidence that has shown reversibility of liver fibrosis and cirrhosis, while commenting on therapeutic safety.Konstantinos Damiris Zaid H Tafesh Nikolaos Pyrsopoulos 2020World Journal of Gastroenterology2020,26,41:8
2Interstitial PDT for vascular anomalies显示文摘Waseem J Tahwinder U Zaid H 2011Lasers in Surgery and Medi- cine2011,43,5:1
3Calcium bindingand translocation by the vohage-dep endentanion channel: a possible reg cerebrovascular ulatory mechanism in mitochondrial function显示文摘Gincel D Zaid H Shoshan-Barmatz V 2001Bioehem J2001,358,1:1
4Cluster roots in Casuarinaceae: role and relationship to soil nutrient factors 显示文摘DIEM H G DUHOUX E ZAID H 2000Annals of Botany2000,85,6:1
5Calcium binding and translocation by the voltage-dependent anion channel:a possible regulatory mechanism in mitochondrial function显示文摘Gincel D Zaid H Shoshan-Barmatz V 2001Blochem J2001,358,1:1
6Effect of reinforcement ratio on the effective moment of inertia of reinforced concrete beams显示文摘Shaikh A H Zaid R Z 1993ACI Structural Journal1993,90,2:1
7Effect of loading type on the effective moment of inertia of reinforced concrete beams 显示文摘Zaid R Z Shaikh A H Hussein M M 1991ACI Structural Journal1991,88,2:1
8Does ethylene mediate cluster root formation under iron deficiency? 显示文摘Zaid H Morabet R E I Diem H G 2003Annals of Botany2003,92,:1
9Calcium binding and translo- cation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function 显示文摘Gincel D Zaid H Shoshan-Barmztz V 2001Biochem J2001,358,1:1
10Cluster roots in Casuarinacea~: Role and relationship to soil nutrient factors显示文摘Diem H G Duhoux E Zaid H 2000Ann Bot2000,855,:1
11Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function 显示文摘Gincel D Zaid H Shoshan-Barmatz V 2001Biochem J2001,358,1:1
12Cluster roots in Casuarinaceae : Role and relationship to soil nutrient factors显示文摘Diem H G Duhoux E Zaid H etal 2000Ann Bot2000,85,:1
13Cluster roots in Casuari-naceae:Role and relationship to soil nutrient factors显示文摘Diem H G Duhoux E Zaid H 2000Ann Bot2000,85,92:1
14Cluster roots in Casuarinaceae: Role and relationship to soil nutrient factors 显示文摘DIEM H G DUHOUX E ZAID H 2000Annals of Botany2000,85,6:1
15Increased level of serum hepatocyte growth factor/ scatter factor in liver cancer is associated with tumor metastasis显示文摘JUNBO H LI Q ZAIDE W 1999In Vivo1999,13,2:1
16Trends in the u- tilization of neoadjuvant chemotherapy in muscle-invasive bladder cancer results from the national cancer database显示文摘ZAID H B PATEL S G STIMSON C J 2014Urology2014,83,1:1
17The voltage-dependent anion channel-1 modulates apoptotic cell death显示文摘Zaid H Abu Hamad S Israelson A 2005Cell Death Differ2005,12,7:1
18Validation and verification of decision making rules显示文摘Zaid A K Levis A H 1997Automatica1997,33,2:1
19Cluster roots in Casuarinaceae: Role and relationship to soil nutrient factors 显示文摘Diem H G Duhoux E Zaid H 2000Ann Bot2000,85,6:1
20The voltage-dependent anion channel-I modulates apoptotic cell death 显示文摘Zaid H Abu-Hamad S Israelson A 2005Cell Death Differ2005,12,:1
返回顶部 每页显示:
共2页 首页 上一页 第1页 下一页 末页 /2 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费