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| 1 | Analysis of Tonal Noise Generating Mechanisms in Low-Speed Axial-Flow Fans显示文摘The present paper reports a comparison of experimental SPL spectral data related to the tonal noise generated by axial-flow fans.A nine blade rotor has been operated at free discharge conditions and in four geometrical configurations in which different kinds of tonal noise generating mechanisms are present:large-scale inlet turbulent structures,tip-gap flow,turbulent wakes,and rotor-stator interaction.The measurements have been taken in a hemi-anechoic chamber at constant rotational speed and,in order to vary the acoustic source strength,during low angular acceleration,linear speed ramps.In order to avoid erroneous quantitative evaluations if the acoustic propagation effects are not considered,the acoustic response functions of the different test configurations have been computed by means of the spectral decomposition method.Then,the properties of the tonal noise generating mechanisms have been studied.To this aim,the constant-Strouhal number SPL,obtained by means of measurements taken during the speed ramps,have been compared with the propagation function.Finally,the analysis of the phase of the acoustic pressure has allowed to distinguish between random and deterministic tonal noise generating mechanisms and to collect information about the presence of important propagation effects. | Edward Canepa Andrea Cattanei Fabio Mazzocut Zecchin | 2016 | Journal of Thermal Science2016,25,4: | 2 |
| 2 | Targeting endothelial cell metabolism: new therapeutic prospects?显示文摘Endothelial 房间 EC 衬里血容器并且为氧和营养素作为一根重要水管工作,但是能也为干细胞的各种各样的类型形成脉管的壁龛。当时主要静止的全部成年的生活, EC 能很快换到一个高度活跃的状态,和开始发芽以便形成新血容器。EC 能也变得不正常,作为发生在糖尿病和动脉粥样硬化。最近的研究在 angiogenesis 的规定为 EC 新陈代谢表明了一个关键角色,并且证明那 EC 新陈代谢甚至能够制服基因信号。在这评论,我们将考察在癌症在糖尿病和容器增生伴随 EC 机能障碍的新陈代谢的改变上的 EC 新陈代谢和焦点的基本原则。我们将也加亮由 modulating translational 以后修正和 epigenetic 的 EC 新陈代谢影响 EC 行为怎么变化,并且说明代谢物的饮食的补充怎么能改变 EC 回答。最后,我们将讨论作为新奇治疗学的策略指向 EC 新陈代谢的潜力。 | Annalisa Zecchin | 2015 | Frontiers in Biology2015,10,2: | 2 |
| 3 | Distinct delta and jagged genes control sequential segregation of pancreatic cell types fromprecursor pools in zebrafish显示文摘 | ZECCHIN E FILIPPI A BIEMAR F | 2007 | Dev Biol2007,301,: | 1 |
| 4 | Expression analysis of jagged genes in zebrafish embryos 显示文摘 | zEcCHIN E CONIGLIARO A TISO N | 2005 | Dev Dyn2005,233,: | 1 |
| 5 | Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis显示文摘 | De Souza Setubal Desteo MF Bitu CC Zecchin KG | 2010 | Int J Oncol2010,36,1: | 1 |
| 6 | Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis显示文摘 | Zecchin KG Rossato FA Raposo HF | 2011 | Lab Invest2011,91,2: | 1 |
| 7 | Improving par- tial mutual information-based input variable selection by consideration of boundary issues associated with bandwidth estimation显示文摘 | LI X ZECCHIN A C MAIER H R | 2015 | Environmental Modelling & Software2015,71,: | 1 |
| 8 | Fatty acid syn- thase inhibition with Orlistat promotes apoptosis and re- duces cell growth and lymph node metastasis in a mouse melanoma model显示文摘 | Carvalho MA Zecchin KG Seguin F | 2008 | Int J Cancer2008,123,11: | 1 |
| 9 | Application of two antcolony optimistation algorithms to distribution system optimisa-tion 显示文摘 | Zecchin R Michael Leonard Simpson R | 2006 | Mathematical and Computer Modelling2006,44,6: | 1 |
| 10 | 显示文摘 | Berlin A Zotti G Zecchin S | 2004 | Chem Mater2004,16,19: | 1 |
| 11 | Insulin signalling pathways in aorta and muscle from two animal models of insulin resistance-the obese middle-aged and the spontaneously hypertensive rats显示文摘 | Zecchin HG Bezerra RM Carvalheira JB | 2003 | Diabetologia2003,46,4: | 1 |
| 12 | Reversible acetylation regulates vascular endothelial growth factor receptor-2 activity显示文摘酷氨酸 kinase 受体(VEGFR2 ) 脉管的 endothelial 生长因素受体 2 是 angiogenesis 的一个关键管理者。VEGFR2 在在 kinaseinsert 领域形成稠密的簇的四离氨酸残余两个都是在 endothelial 房间的 acetylated,在一个单身者,离氨酸在受体激活环定位的 Herewe 表演。这些修正在动态 controlof 下面是 acetyltransferase p300 和二 deacetylases HDAC5 和 HDAC6。我们实质上表明那 VEGFR2 acetylation regulatesreceptor phosphorylation。特别地, VEGFR2 acetylation 显著地改变受体 phosphorylationafter ligand 绑定的动力学,允许受体 phosphorylation 并且在在激活循环的离氨酸的那 acetylation 贡献的有模拟显示的 VEGF.Molecular 动力学的延长刺激之上的细胞内部的发信号 transitionto 一个开的活跃状态,在哪个酷氨酸 phosphorylation 被 kinase 目标残余的更好的暴露赞成。Thesefindings 显示由 acetylation 的那 translational 以后修正是直接影响 VEGFR2function 的批评机制。 | Annalisa Zecchin Lucia Pattarini Maria Ines Gutierrez Miguel Mano Antonello Mai Sergio Valente Mike P. Myers Sergio Pantano Mauro Giacca | 2014 | Journal of Molecular Cell Biology2014,8,2: | 1 |
| 13 | The cross talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinaseand mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance显示文摘 | CARVALHEIRA J B CALEGARI V C ZECCHIN H G | 2003 | Endocrinology2003,144,: | 1 |
| 14 | Defective insulin and acetylcholine induction of endothelial cell-nitric oxide synthase through insulin receptor substrate/Akt signaling pathway in aorta of obese rats显示文摘 | Zecchin H6 Priviero FB Souza CT | 2007 | Diabetes2007,56,4: | 1 |
| 15 | Early appearance of pancreatic hormone-expressing cells in the zebrafish embryo显示文摘 | ARGENTON F ZECCHIN E BORTOLUSSI M | 1999 | Mech Dev1999,87,: | 1 |
| 16 | Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus显示文摘 | Di Nicolantonio Federica Arena Sabrina Tabernero Josep Grosso Stefano Molinari Francesca Macarulla Teresa Russo Mariangela Cancelliere Carlotta Zecchin Davide Mazzucchelli Luca Sasazuki Takehiko Shirasawa Senji Geuna Massimo Frattini Milo Ba | 2010 | Journal of Clinical Investigation2010,,8: | 1 |
| 17 | Persistence of restrictive left ventricular filling pattern in dilated cardiomyopathy: an ominous prognostic sign显示文摘 | Pinamonti B Zecchin M Di Lenarda A Gregori D Sinagra G Camerini F | 1997 | J Am Coll Cardiol1997,29,: | 1 |
| 18 | Overexpres-sion of HOXB7 homeobox gene in oral cancer induces cellular prolif-eration and is associated with poor prognosis显示文摘 | De Souza Setubal Destro MF Bitu CC Zecchin KG | 2010 | Int J Oncol2010,36,: | 1 |
| 19 | Resistênciaàinsulina,diabetes ehipertens?o:bases fisiopatológicas显示文摘 | Zecchin HG Carvalheira JBC Saad MJA | 2004 | Rev Bras Hipertens2004,11,2: | 1 |
| 20 | Persistence of restrictive left ventricular filling pattern in dilated cardiomyopathy : an ominous prognostic sign显示文摘 | PINAMONTI B ZECCHIN M LENARDA A | 1997 | J Am Coll Cardiol1997,29,: | 1 |