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| 1 | Histological abnormalities of the small bowel mucosa in cirrhosis and portal hypertension显示文摘AIM: To study the small bowel (SB) mucosa on biopsy in cirrhotic patients with portal hypertension and in non-cirrhotic controls and grade fi ndings according to the Marsh criteria. METHODS: We prospectively enrolled 51 consecutive patients undergoing an upper endoscopy for their routine medical care. Twenty f ive patients with cirrhosis and portal hypertension were compared to 26 controls. We obtained coeliac serology and multiple upper small bowel biopsies on all 51 patients. A GI pathologist interpreted biopsies and graded fi ndings according to the Marsh criteria. We assessed equivalence in Marsh grade between cirrhotic and non-cirrhotic controls using the Mann-Whitney test for equivalence. RESULTS: Gender, ethnicity and age were similar between both groups. Marsh grades were equivalent between the groups. Grade of 0 was present in 96% and grade of 1 was present in 4% of both groups and there was no villus atrophy or decrease in villus/crypt ratio in patients with portal hypertension. CONCLUSION: This study provides evidence for the lack of villus atrophy in patients with cirrhosis and portal hypertension, and supports the continuous reliance on the Marsh criteria when the diagnosis of coeliac disease is to be made in the presence of cirrhosis. | Jamilé Wakim-Fleming Nizar N Zein Ana Bennett Rocio Lopez Janice Santisi William D Carey | 2008 | World Journal of Gastroenterology2008，14，41： | 4 |
| 2 | Polymorphisms in the interleukin-10, tumor necrosis factor-α, and transforming growth factor-β1 genes in chronic hepatitis C patients treated with interferon and ribavirin显示文摘 | Pedro G Vidigal Jeffrey J Germer Nizar N Zein | 2002 | Journal of Hepatology2002，，2： | 2 |
| 3 | Safety of antitumour necrosis factor (anti-TNF) therapy in patients with chronic viral infections: hepatitis C, hepatitis B, and HIV infection显示文摘 | Calabrese LH Zein N Vassilopoulos D | 2004 | Ann Rheum Dis2004，63，2： | 1 |
| 4 | Predictive accuracy of serum hyaluronic acid as a non-invasive marker of fibrosis in a cohort of multi-transfused Egyptian children withβ-thalassaemia major显示文摘 | El-Shabrawi MH Zein El Abedin MY Omar N | | 0，，02： | 1 |
| 5 | Clinical significance of hepatitis C virus genotypes显示文摘 | Zein N N | 2000 | Clin Microbiol Rev2000，13，2： | 1 |
| 6 | Interleukin-2 liposomes for primary immune deficiency using the aerosol route 显示文摘 | Ten R M Anderson P M Zein N N | 2002 | Int Immunopharmacol2002，2，23： | 1 |
| 7 | Human natural Treg microRNA signature: role of microRNA-31 and microRNA 21 in FOXP3 expression 显示文摘 | Rouas R Fayyad Kazan H E1 Zein N etal | 2009 | Ear J Immunol2009，39，： | 1 |
| 8 | The epidemiology and natural history of hepatitis C virus infection显示文摘 | Zein N | 2003 | Clevel and Clin J Med2003，70，1： | 1 |
| 9 | Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression显示文摘 | Rouas R Fayyad-Kazan H E1 Zein N | 2009 | Eur J Immunol2009，39，6： | 1 |
| 10 | VIP differentially activates be-ta2 integrins, CR1, and matrix metalloproteinase-9 in humanmonocytes through cAMP/ PKA, EPAC, and PI - 3K signalingpathways via VIP receptor type 1 and FPRL1显示文摘 | El Zein N Badran B Sariban E | 2008 | J Leukoc Biol2008，83，4： | 1 |
| 11 | Human natural Treg microRNA signature : Role of microRNA-31 and microRNA-21 in FOXP3 expression 显示文摘 | Rouas R Fayyad-Kazan H E1 Zein N | 2009 | Eur J Immunol2009，39，6： | 1 |
| 12 | Human natural Treg microRNA signature:role of microRNA-31 and mi- croRNA-21 in FOXP3 expression显示文摘 | Rouas R Fayyad-Kazan H El Zein N etal | 2009 | Euro J Immunol2009，39，： | 1 |
| 13 | Prevalence of diabetes mellitus in patients with end-stage liver cirrhosis due to hepatitis C,alcohol,or cholestatic disease显示文摘 | Zein N Abdulkarim AS Wiesner RH | | 0，，02： | 1 |
| 14 | Spontaneous bacterial peritonitis: recent data on incidence and treatment显示文摘 | PARSI M A ATREIA A ZEIN N N | 2004 | Cleve Clin J Med2004，71，7： | 1 |
| 15 | Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 inFOXP3 expression显示文摘 | Rouas R Fayyad-Kazan H El Zein N | 2009 | Eur J Immunol2009，39，： | 1 |
| 16 | The effect of FIFA 11+ as an injury prevention program in youth futsal players 显示文摘 | ZEIN M KURNIAROBBI J AGUNG N | 2014 | Bri J Sports Med2014，48，67： | 1 |
| 17 | Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment 显示文摘 | CHRISTINE CARTER-KENT MD NIZAR N ZEIN ARIEL E FELDSTEIN | 2008 | The American Journal of Gastroenterology2008，103，： | 1 |
| 18 | Spontaneous clearance of chronic hepatitis C during pregnancy显示文摘 | Claudia O Zein Haitham Abu-Lebdeh Nizar N Zein | 2001 | The American Journal of Gastroenterology2001，，10： | 1 |
| 19 | Secondary urinoma mimicking reccurrent tumor as a cause of bilateral ureteral obstruction 显示文摘 | ZEIN TA HUBEN RP PETREL N J | 1987 | J Surg Onco1987，34，： | 1 |
| 20 | Three - di- mensional print of a liver for preoperative planning in living donor liver transplantation显示文摘 | ZEIN N N HANOUNEH I A BISHOP P D | 2013 | Liver Transpl2013，19，12： | 1 |
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