|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diagnostic and prognostic value of circulating micro RNAs in heart failure with preserved and reduced ejection fraction显示文摘micro RNAs(mi RNAs) are powerful regulators of posttranscriptional gene expression and play an important role in pathophysiological processes. Circulating mi RNAs can be quantified in body liquids and are promising biomarkers in numerous diseases. In cardiovascular disease mi RNAs have been proven to be reliable diagnostic biomarkers for different disease entities. In cardiac fibrosis(CF) and heart failure(HF) dysregulated circulating mi RNAs have been identified,indicating their promising applicability as diagnostic biomarkers. Some mi RNAs were successfully tested in risk stratification of HF implementing their potential use as prognostic biomarkers. In this respect mi RNAs might soon be implemented in diagnostic clinical routine. In the young field of mi RNA based research advances have been made in identifying mi RNAs as potential targets for the treatment of experimental CF and HF. Promising study results suggest their potential future application as therapeutic agents in treatment of cardiovascular disease. This article summarizes the current state of the various aspects of mi RNA research in the field of CF and HF with reduced ejection fraction as well as preserved ejection fraction. The review provides an overview of the application of circulating mi RNAs as biomarkers in CF and HF and current approaches to therapeutically utilize mi RNAs in this field of cardiovascular disease. | Christian Schulte Dirk Westermann Stefan Blankenberg Tanja Zeller | 2015 | World Journal of Cardiology2015，7，12： | 11 |
| 2 | 酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。 | 陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB | 2021 | 中华高血压杂志2021，29，2： | 9 |
| 3 | D-二聚体预测稳定型冠状动脉性心脏病患者的长期病因特异性死亡率、心血管事件和癌症显示文摘交联纤维蛋白的降解产物D-二聚体是高凝状态和血栓形成事件的标志。D-二聚体水平中度升高与血管疾病患者静脉和动脉事件的风险相关。在缺血性疾病长期普伐他汀干预(long-term intervention with pravastatin in ischemic disease,LIPID)试验中,研究者在存在其他危险因素的背景下,评估了D-二聚体水平在预测长期血管转归、病因特异性死亡率和新发癌症中的作用。 | 刘青 叶鹏 Simes J Robledo KP White HD Espinoza D Stewart RA Sullivan DR Zeller T Hague W Nestel PJ Glasziou PP Keech AC Elliott J Blankenberg S Tonkin AM LIPID study investigators | 2018 | 中华高血压杂志2018，26，3： | 6 |
| 4 | 小麦资源胚乳蛋白Glu-1、Glu-3、Gli-1基因位点变异特点显示文摘141个普通小麦品种及农家种中,由Glu-1位点控制的高分子量谷蛋白亚基共27种图谱,最常见的图谱是(N,7+8,2+12)占22%和(N,7+9,2+12)占19.9%,Glu-A1、Glu-B1、Glu-D1位点控制的均为正效应亚基,其图谱(1,7+8,5+10),(1,14+15,5+10),(1,13+16,5+10),(1,17+18,5+10),(2*,7+8,5+10),(2*,13+16,5+10)占13.4%;由Glu-3位点控制的低分子量谷蛋白亚基共48种以上的图谱,最常见的图谱是(a,j,c),Glu-A3位点存在6个以上等位基因,新发现的占5.7%,Glu-B3位点存在10个以上等位基因,新发现的占2.8%,Glu-D3位点存在3个等位基因;由Gli-1位点控制的醇溶蛋白共81种以上图谱,Gli1-A1位点存在7个以上等位基因,新发现的占7.1%,Gli-B1位点存在12个以上等位基因,新发现的等位基因占3.5%,Gli-D1位点存在10个等位基因,Gli-B1位点的l为1B/1R易位系,占总数的33.6%;由Gli-1位点控制的醇溶蛋白和由Glu-3位点控制的低分子量谷蛋白亚基基因变异远比由Glu-1位点控制的高分子量谷蛋白亚基复杂和丰富。 | 王瑞 张改生 F J Zeller S L K Hsam | 2006 | 作物学报2006，32，4： | 4 |
| 5 | Control of T H 17/T reg Balance by Hypoxia-Inducible Factor 1显示文摘 | Eric V. Dang Joseph Barbi Huang-Yu Yang Dilini Jinasena Hong Yu Ying Zheng Zachary Bordman Juan Fu Young Kim Hung-Rong Yen Weibo Luo Karen Zeller Larissa Shimoda Suzanne L. Topalian Gregg L. Semenza Chi V. Dang Drew M. Pardoll Fan Pan | 2011 | Cell2011，，5： | 3 |
| 6 | Tree species richness enhances stand productivity while stand structure can have opposite effects, based on forest inventory data from Germany and the United States of America显示文摘Background: In recent studies, mixed forests were found to be more productive than monocultures with everything else remaining the same.Methods: To find out if this productivity is caused by tree species richness, by a more heterogeneous stand structure or both, we analyzed the effects of forest structure and tree species richness on stand productivity, based on inventory data of temperate forests in the United States of America and Germany.Results: Having accounted for effects such as tree size and stand density, we found that:(Ⅰ) tree species richness increased stand productivity in both countries while the effect of tree size heterogeneity on productivity was negative in Germany but positive in the USA;(Ⅱ) productivity was highest at sites with an intermediate amount of precipitation; and(Ⅲ) growth limitations due water scarcity or low temperature may enhance structural heterogeneity.Conclusions: In the context of forest ecosystem goods and services, as well as future sustainable forest resource management, the associated implications would be:Tree species richness is vital for maintaining forest productivity.As an optimum amount of precipitation is accompanied by the highest productivity, changes in climatic conditions should be considered when planning.Resource limitations enhance structural heterogeneity, which in turn can have positive or negative effects on stand productivity.Furthermore, we discuss the difficulties encountered when analyzing different national forest inventories and large data sets. | Laura Zeller Jingjing Liang Hans Pretzsch | 2018 | Forest Ecosystems2018，5，1： | 3 |
| 7 | 根据基础降压用药分析恩格列净在2型糖尿病合并高血压患者中的降压作用显示文摘在EMPA—REG血压试验中,与安慰剂比较,恩格列净(empagliflozin)10或25mg/d可降低2型糖尿病合并高血压患者的糖化血红蛋白、血压及体质量水平。 | Mancia G Cannon CP Tikkanen I Zeller C Ley L Woerle HJ Broedl UC Johansen OE 赵狄 练桂丽 | 2016 | 中华高血压杂志2016，24，10： | 3 |
| 8 | 49份小麦种质资源中Glu-1,Glu-3,Gli-1位点基因组成分析显示文摘采用分步法SDS-PAGE和改良A-PAGE分析了49份小麦农家品种等资源的Glu-1,Glu-3,Gli-1位点基因组成.结果表明,Glu-1位点编码的HMW-GS组成共检测到14种图谱,其中占比例最大图谱(N,7+8,2+12)达44.9%,其次是(N,7+9,2+12)和(1,7+8,2+12)各占14.3%,(1,7+9,5+10)和(2*,7+9,2+12)各占4.1%,其余9种图谱各占2.0%;Glu-3位点编码的LMW-GS组成共检测到25种图谱,(a,j,c)占12.2%,(a,g,c)占10.2%,(new,g,c)占8.2%,(a,g,a),(a,j,a),(f,g,c)和(d,j,a)各占6.1%,(f,j,a),(d,g,c),(a,f,c)和(f,f,c)各占4.1%,其余14种图谱各占2.0%,Glu-A3位点新发现的基因图谱占14.3%;Gli-1位点编码的醇溶蛋白组成共检测到40种图谱,(a,f,l)和(f,l,i)各占6.1%,(f,l,a),(new,c,i),(b,g,l)和(l,l,a)各占4.1%,其它34种图谱各占2.0%,Gli-1位点新发现的基因图谱占16.3%;扬白麦、迟亚草、葫芦头麦、红秃头、红粒白芒、红火麦、矮孟牛IV中在Glu-3或Gli-1位点含有新发现的等位基因. | 王瑞 张改生 王宏 F J ZELLER S L K HSAM | 2008 | 河南农业大学学报2008，42，4： | 2 |
| 9 | Molecular characterization and dynamic expression patterns of two types of γ-gliadin genes from Aegilops and Triticum species显示文摘 | Shunli Wang Xixi Shen Pei Ge Jie Li Saminathan Subburaj Xiaohui Li F. J. Zeller S. L. K. Hsam Yueming Yan | 2012 | Theoretical and Applied Genetics2012，，7： | 2 |
| 10 | 一些小麦1B/1R易位系品质基因多样性分析显示文摘利用SDS-PAGE和A-A-PAGE分析了38份小麦1B/1R易位系Glu-1、Glu-3、Gli-1位点基因组成。结果表明,小麦1B/1R易位系中品质基因多样性降低,Glu-1、Glu-3编码的高、低分子量谷蛋白亚基种类减少,Glu-B1位点含有的优质亚基比例明显下降,Gli-1位点编码的醇溶蛋白比例增加,导致劣质。因此对于抗病品种品质改良要着重于改变其遗传组成尤其是Glu-1、Glu-3、Gli-1位点基因组成,尽可能打破Glu-3、Gli-1位点基因连锁关系,淘汰Glu-3位点基因的j,导入一些优良的品质基因。 | 王瑞 张改生 王宏 F J Zeller S L KHsam | 2007 | 西北农业学报2007，16，1： | 2 |
| 11 | Difference between expression of adhesion molecules on CD34+ cells from bone marrow and G-CSF-stimulated peripheral blood 显示文摘 | Kroger N Zeller W Hassan HT | 1998 | Stem Cells1998，16，： | 2 |
| 12 | ST2可能并非心血管事件、心力衰竭和死亡有用的预测因子显示文摘研究人员假设可溶性ST2(soluble ST2,sST2)水平可识别出心血管疾病(cardiovascular disease,CVD)风险较高的人群,应将其纳入风险预测计算指标。ST2是炎症性细胞因子白细胞介素33的受体。sST2水平增加与急性心肌梗死患者和一般人群的心力衰竭及死亡相关。方法:研究人员测定FINRISK97前瞻性研究人群队列中的8444名男性和女性(25-74岁)的高敏sST2水平,应用Cox比例风险模型评估在15年的随访中,sST2对致命性或非致命性心力衰竭、CVD(冠状动脉性心脏病和脑卒中)、糖尿病和死亡情况的预测能力。研究者获取10年绝对风险识别和重新分类的统计数据, | 赵狄 叶鹏 Hughes MF Appelbaum S Havulinna AS Jagodzinski A Zeller T2 Kee F Blankenberg S Salomaa V | 2014 | 中华高血压杂志2014，22，8： | 2 |
| 13 | Difference between expression of adhesion molecules on CD+34 cells from bone marrow and G-CSF-stimulated peripheral blood显示文摘 | Zeller W Hassan HT | 1998 | Stem Cells1998，16，1： | 1 |
| 14 | Prevalence and impact of metabolic syndrome on hospital outcomes in acute myocardial infraction显示文摘 | Zeller M Steg P Ravisy J | 2005 | Arch Intern Med2005，65，10： | 1 |
| 15 | Copeptin improves early diagnosis of acute myocardial infarction显示文摘 | Keller T Tzikas S Zeller T | 2010 | J Am Coll Cardiol2010，55，19： | 1 |
| 16 | Phenotype of lymphocyte subsets after autologous peripheral blood stem cell transplantation显示文摘 | Koehne G Zeller W Stockschlaeder M | 1997 | Bone Marrow Transplant1997，19，2： | 1 |
| 17 | Candidate DNA meth-ylation drivers of acquired cisplatin resistance in ovariancancer identified by methyiome and expression profiling显示文摘 | Zeller C Dai W Steele NL | 2012 | Oncogene2012，31，： | 1 |
| 18 | Renal +lrtery stenosis: Up-date on diagnosis and trealrnenl显示文摘 | Zeller T Maeharzina R Rastan A | 2014 | Vasa2014，43，1： | 1 |
| 19 | Asymmetric dimelhylarginine (ADMA) and hyperhomocysteinemia in patients with acute myocardial infarction 显示文摘 | Korandji C Zeller M Guilland JC | 2007 | Clin Biochem2007，40，12： | 1 |
| 20 | Vaccination associated thrombocytopenic purpura in children 显示文摘 | RAJANTIE J ZELLER B TREUTIGER I | 2007 | Vaccine2007，25，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员