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| 1 | Effects of electric parameters on microstructure and properties of MAO coating fabricated on ZK60 Mg alloy in dual electrolyte显示文摘Micro-arc oxidation (MAO) process was carried out in a dual electrolyte system of NaAlO 2 and Na 3 PO 4 on ZK60 Mg alloys to explore the effect of electric parameters including current density, frequency, duty cycle and oxidation time on the evolution of coatings and other characteristics. The microstructural characteristics of coatings were observed by scanning electron microscopy (SEM) combined with the analysis of voltage-time responses during MAO process. Test of weight loss was conducted at a 3.5% NaCl solution to assess the resistance to corrosion. The results indicate that the current density and duty cycle play key roles on the coating quality. The peak voltage during MAO process increased with the increase in current density but the coating would be more easily detached when the current density was beyond a critical value. Voltage during MAO and microstructure of the coating were affected remarkably by duty cycle, and corrosion resistance was improved greatly when duty cycle was 40%. By means of single variable experiments, MAO process with optimized electric parameters was developed, which corresponds to the current density of 20 A dm 2 , frequency of 500 Hz, duty cycle of 40% and oxidation time of 15 min. | Chen, Jing Wang, Zexin Lu, Sheng | 2012 | Rare Metals2012，31，2： | 9 |
| 2 | In-situ surface decoration of RuO_(2) nanoparticles by laser ablation for improved oxygen evolution reaction activity in both acid and alkali solutions显示文摘Improving the OER activity of noble metal-based materials is of profound importance to minimize the usage of noble metals and lower the cost.Here,we report considerable improvement on the catalytic activity of RuO_(2) particles for OER in both alkali and acid environments.The RuO_(2) nanoparticles were treated with a method of pulse laser ablation.Numerous Ru and RuO_(2) clusters were generated at the surface of RuO_(2) nanoparticles after the laser ablation,forming a lychee-shaped morphology.The larger pulse energy RuO_(2) nanoparticles are treated with,the better the OER activity can be.DFT calculations shows that the surface tension induced by the lychee-shaped morphology benefits the OER performance.Our best sample gives an overpotential of 172 mV(at 10 mA cm^(-2))and a Tafel slope of 53.5 mV dec^(-1) in KOH,while an overpotential of 219 mV and a Tafel slope of 44.9 mV dec^(-1) in H_(2)SO_(4),which are of topclass results.This work may inspire a new way to develop high-performance electrocatalysts for OER. | Zongpeng Wang Beibei Xiao Zhiping Lin Shijie Shen Aijiao Xu Zexin Du Yuchao Chen Wenwu Zhong | 2021 | Journal of Energy Chemistry2021，30，3： | 4 |
| 3 | Andrographolide and Its Derivative Potassium Dehydrographolide Succinate Suppress PRRSV Replication in Primary and Established Cells via Differential Mechanisms of Action显示文摘Porcine reproductive and respiratory syndrome virus(PRRSV) continues to cause significant economic loss worldwide and remains a serious threat to the pork industry. Currently, vaccination strategies provide limited protection against PRRSV infection, and consequently, new antiviral strategies are urgently required. Andrographolide(Andro) and its derivative potassium dehydrographolide succinate(PDS) have been used clinically in China and other Asian countries as therapies for inflammation-related diseases, including bacterial and viral infections, for decades. Here, we demonstrate that Andro and PDS exhibit robust activity against PRRSV replication in Marc-145 cells and primary porcine alveolar macrophages(PAMs). The two compounds exhibited broad-spectrum inhibitory activities in vitro against clinically circulating type 2 PRRSV GD-HD, XH-GD, and NADC30-like HNhx strains in China. The EC_(50)values of Andro against three tested PRRSV strain infections in Marc-145 cells ranged from 11.7 to 15.3 lmol/L, with selectivity indexes ranging from 8.3 to10.8, while the EC_(50)values of PDS ranged from 57.1 to 85.4 lmol/L, with selectivity indexes ranging from 344 to 515.Mechanistically, the anti-PRRSV activity of the two compounds is closely associated with their potent suppression on NFj B activation and enhanced oxidative stress induced by PRRSV infection. Further mechanistic investigations revealed that PDS, but not Andro, is able to directly interact with PRRSV particles. Taken together, our findings suggest that Andro and PDS are promising PRRSV inhibitors in vitro and deserves further in vivo studies in swine. | Lizhan Su Yarou Gao Mingxin Zhang Zexin Liu Qisheng Lin Lang Gong Jianying Guo Lixia Chen Tongqing An Jianxin Chen | 2021 | Virologica Sinica2021，36，6： | 4 |
| 4 | Associations of noniodized salt and thyroid nodule among the Chinese population: a large cross-sectional study1234显示文摘 | Zexin Chen Weimin Xu Yangmei Huang Xingyi Jin Jin Deng Sujuan Zhu Hui Liu Shanchun Zhang Yunxian Yu | 2013 | American Journal of Clinical Nutrition2013，，3： | 3 |
| 5 | Multi-objective Optimization Design of Inset-surface Permanent Magnet Machine Considering Deterministic and Robust Performances显示文摘The inset-surface permanent magnet(ISPM)machine can achieve the desired electromagnetic performance according to the traditional deterministic design.However,the reliability and quality of the machine may be affected by the essential manufacturing tolerances and unavoidable noise factors in mass production.To address this weakness,a comprehensive multi-objective optimization design method is proposed,in which robust optimization is performed after the deterministic design.The response surface method is first adopted to establish the optimization objective equation.Afterward,the sample points are obtained via Monte Carlo simulation considering the design-variable uncertainty.The Design for Six Sigma approach is adopted to ensure the robustness of the design model.Furthermore,the barebones multi-objective particle swarm optimization algorithm is used to obtain a compromise solution.A prototype is manufactured to evaluate the effectiveness of the proposed method.According to the finite-element analysis and experimental tests,the electromagnetic performance and reliability of the machine are significantly enhanced with the proposed method. | Gaohong Xu Zexin Jia Wenxiang Zhao Qian Chen Guohai Liu | 2021 | Chinese Journal of Electrical Engineering2021，7，3： | 2 |
| 6 | Two vs three cycles of neoadjuvant sintilimab plus chemotherapy for resectable non-small-cell lung cancer:neoSCORE trial显示文摘Dear Editor,Lung cancer is the predominant cause of cancer-related deaths globally,with non-small cell lung cancer(NSCLC)accounting for 85%of all cases.1 The five-year overall survival(OS)after surgery remains poor because of the high rate of postoperative recurrence and metastasis.Recently,immune checkpoint inhibitors(ICIs)have shown promising efficacy in resectable NSCLC. | Miner Shao Jie Yao Yunke Wang Lufeng Zhao Baizhou Li Lili Li Zuqun Wu Zexin Chen Junqiang Fan Fuming Qiu | 2023 | Signal Transduction and Targeted Therapy2023，8，5： | 1 |
| 7 | Structural optimization of 2-D array probe for ACFM显示文摘 | CHEN Guoming LI Wei WANG Zexin | 2007 | NDT&E International2007，40，6： | 1 |
| 8 | Associations of uoniodized salt and thyroid nodule among the Chinese population: a large cross- sectional study显示文摘 | Zexin Chen Weimin xu Yangmei Huang | 2013 | The American Journal of Clinical Nutrition2013，98，： | 1 |
| 9 | Structural optimazation of 2-D array probe for alternaing current field measurement显示文摘 | Chen Guoming Li Wei Wang Zexin | 2007 | NDT&E International2007，40，6： | 1 |
| 10 | Achieving high yield of Ti3C2Tx MXene few-layer flakes with enhanced pseudocapacior performance by decreasing precursor size显示文摘Ti3C2Tx,a most studied member of MXene family,shows promise as a candidate electrode for pseudocapacitor due to its electronic conductivity and hydrophilic surface.However,the unsatisfactory yield of Ti3C2Tx few-layer flakes significantly restricted it in real applications.Here,we proposed a simple solution to boost the yield of Ti3C2Tx few-layer flakes by decreasing precursor size.When using the small500 mesh Ti3AlC2 powders as raw material,high yield of 65%was successfully achieved.Moreover,the asreceived small flakes also exhibit an enhanced pseudocapacior performance owing to their excellent electrical conductivity,expanded inte rlayer space and more O content on the surface.This work not only sheds light on the cost effective mass production of Ti3C2Tx few-layer flakes,but also provides an efficient solution for the design of MXene electrodes with high pseudocapacior performance. | Jianguang Xu Jiale Zhu Chen Gong Zexin Guan Dan Yang Zhihan Shen Wei Yao Haijiang Wu | 2020 | Chinese Chemical Letters2020，31，4： | 1 |
| 11 | Structural optimization of 2-D array probe for alternating current field measurement显示文摘 | CHEN Guoming LI Wei WANG Zexin | 2007 | NDT&E International2007，40，6： | 1 |
| 12 | Zero-valent manganese nanoparticles coupled with different strong oxidants for thallium removal from wastewater显示文摘Nano zero-valent manganese(nZVMn,Mn^0)was prepared through a borohydride reduction method and coupled with different oxidants(persulfate(S2O8^2-),hypochlorite(CIO^-),or hydrogen peroxide(H2O2))to remove thallium(TI)from wastewater.The surface of Mn°was readily oxidized to form a core-shell composite(MnOx@Mn°),which consists of Mn°as the inner core and MnOr(MnO,M112O3,and Mn3O4)as the outer layer.When Mn^0 was added alone,effective T1(I)removal was achieved at high pH levels(>12).The Mn-H2O2 system was only effective in T1(I)removal at high pH(>12),while the Mn^0-S2O8^0or Mn0-ClO^-system had excellent T1(I)removal(>96%)over a broad pH range(4-12).The Mn-S2O8 oxidation system provided the best resistance to interference from an external organic matrix.The isotherm of T1(I)removal through the Mn°-S2O8^2-system followed the Freundlich model.The Mn°nanomaterials can activate persulfate to produce sulfate radicals and hydroxyl radicals.Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy suggested that oxidation-induced precipitation,surface adsorption,and electrostatic attraction are the main mechanisms for T1(I)removal resulting from the combination of Mn^0 and oxidants.Mn^0coupled with S2O8^2-/ClO^-is a novel and effective technique for T1(I)removal,and its application in other fields is worthy of further investigation. | Keke Li Huosheng Li Tangfu Xiao Gaosheng Zhang Aiping Liang Ping Zhang Lianhua Lin Zexin Chen Xinyu Cao Jianyou Long | 2020 | Frontiers of Environmental Science & Engineering2020，14，2： | 1 |
| 13 | Co-administration of platelet-rich plasma and small intestinal submucosa is more beneficial than their individual use in promoting acute skin wound healing显示文摘Background:Acute skin wounds may compromise the skin barrier,posing a risk of infection.Small intestinal submucosa(SIS)is widely used to treat acute and chronic wounds.However,the efficacy of SIS to accelerate wound healing still needs to be improved to meet clinical demands.To tackle this problem,platelet-rich plasma(PRP)is used due to its potency to promote proliferation,migration and adhesion of target cells.In this study,we applied PRP and SIS to skin wounds to explore their effects on wound healing by evaluating re-epithelialization,collagen production,angiogenesis and the inflammatory response.Methods:A1×1-cm full-thickness skin defectwas established in mice.Sixty mice were divided into four treatment groups:PRP+SIS,PRP,SIS and control.On days 3,5,7,10 and 14 post-surgery,tissue specimens were harvested.Haematoxylin and eosin,Masson’s trichrome,immunohistochemical and immunofluorescence double staining were used to visualize epidermal thickness,collagen and vascular regeneration and inflammation.Results:Wound contraction in the PRP and PRP+SIS groups was significantly greater,compared with the other groups,on days 3 and 5 post-surgery.A histological analysis showed higher collagen expression in the PRP and PRP+SIS groups on day 7,whichwas associated with a thicker epidermal layer on day 14.In addition,immunohistochemical staining showed that CD31-positive blood vessels and vascular endothelial growth factor expression in the PRP+SIS and PRP groups were significantly higher,compared with the control group.Furthermore,immunofluorescence double staining showed that the number of M1 and M2 macrophages in the PRP+SIS and PRP groups was higher,compared with the control and SIS groups alone,on day 3.However,on day 7,the number of M1 macrophages dramatically decreased in the PRP+SIS and PRP groups.The ratio of M2 to M1 macrophages in the PRP+SIS and PRP groups was 3.97 and 2.93 times that of the control group and 4.56 and 3.37 times that of the SIS group,respectively.Conclusion:Co-administration of SIS and PRP has a better effect on promoting angiogenesis,reepithelialization and collagen regeneration in managing acute wound healing than either agent alone. | Xiaoxuan Lei Liuhanghang Cheng Yu Yang Mengru Pang Yunqing Dong Xuanru Zhu Caihong Chen Zexin Yao Gang Wu Biao Cheng Tymour Forouzanfar | 2021 | Burns & Trauma2021，9，1： | 1 |
| 14 | Structural optimization of 2D array probe for alternating current field measurement显示文摘 | Chen Guoming Li Wei Wang Zexin | 2007 | NDT&E International2007，40，： | 1 |
| 15 | GmGPDH12,a mitochondrial FAD-GPDH from soybean, increases salt and osmotic stress resistance by modulating redox state and respiration显示文摘In plants,glycerol-3-phosphate dehydrogenase(GPDH)catalyzes the interconversion of glycerol-3-phosphate(G3P)and dihydroxyacetone phosphate(DHAP)coupled to the reduction/oxidation of the nicotinamide adenine dinucleotide(NADH)pool,and plays a central role in glycerolipid metabolism and stress response.Previous studies have focused mainly on the NAD+-dependent GPDH isoforms,neglecting the role of flavin adenine dinucleotide(FAD)-dependent GPDHs.We isolated and characterized three mitochondrialtargeted FAD-GPDHs in soybean,of which one isoform(GmGPDH12)showed a significant transcriptional response to NaCl and mannitol treatments,suggesting the existence of a major FAD-GPDH isoform acting in soybean responses to salt and osmotic stress.An enzyme kinetic assay showed that the purified GmGPDH12 protein possessed the capacity to oxidize G3P to DHAP in the presence of FAD.Overexpression and RNA interference of GmGPDH12 in soybean hairy roots resulted in elevated tolerance and sensitivity to salt and osmotic stress,respectively.G3P contents were significantly lower in GmGPDH12-overexpressing hair roots and higher in knockdown hair roots,indicating that GmGPDH12 was essential for G3P catabolism.A significant perturbation in redox status of NADH,ascorbic acid(ASA)and glutathione(GSH)pools was observed in GmGPDH12-knockdown plants under stress conditions.The impaired redox balance was manifested by higher reactive oxygen species generation and consequent cell damage or death;however,overexpressing plants showed the opposite results for these traits.GmGPDH12 overexpression contributed to maintaining constant respiration rates under salt or osmotic stress by regulating mRNA levels of key mitochondrial respiratory enzymes.This study provides new evidence for the roles of mitochondria-localized GmGPDH12 in conferring resistance to salt or osmotic stress by maintaining cellular redox homeostasis,protecting cells and respiration from oxidative injury. | Ying Zhao Xin Li Zexin Zhang Wenjing Pan Sinan Li Yun Xing Wanying Xin Zhanguo Zhang Zhenbang Hu Chunyan Liu Xiaoxia Wu Zhaoming Qi Dawei Xin Qingshan Chen | 2021 | The Crop Journal2021，9，1： | 1 |
| 16 | Sturctural optimization of2-D array probe for ACFM显示文摘 | CHEN Guoming LI Wei WANG Zexin | 2007 | NDT&EInternational2007，40，6： | 1 |
| 17 | Structural Optimization of 2-D Array Probe for ACFM 显示文摘 | CHEN Guoming LI Wei WANG Zexin | 2007 | NDT&E International (S0963-8695)2007，40，6： | 1 |
| 18 | Dodecyl Mercaptan Functionalized Copper Mesh for Water Repellence and Oil-water Separation显示文摘Reckless discharge of industrial wastewater and domestic sewage as well as frequent leakage of crude oil have caused serious environmental problems and posed severe threat to human survival.Various nature inspired superhy-drophobic surfaces have been successfully applied in oily water remediation.However,further improvements are still urgently needed for practical application in terms of facile synthesis process and long-term durability towards harsh environment.Herein,we propose a simple one-step dodecyl mercaptan functionalization method to fabricate Super-hydrophobic-Superoleophilic Copper Mesh(SSCM).The prepared SSCM possesses excellent water repellence and oil affinity,enabling it to successfully separate various oil-water mixtures with high separation efficiency(e.g.,>99%for hexadecane-water mixture).The SSCM retains high separating ability when hot water and strong corrosive aqueous solutions are used to simulate oil-water mixtures,indicating remarkable chemical durability of the dodecyl mercaptan functionalized copper mesh.Additionally,the efficiency can be well maintained during 50 cycles of separation,and the water repellence is even stable after storage in air for 120 days,demonstrating the reusability and long-term stability of the SSCM.Furthermore,the functionalized mesh also shows good mechanical robustness towards abrasion by sandpaper,and oil-water separation efficiency of>96%can be obtained after 10 cycles of abrasion.The reported one-step dodecyl mercaptan functionalization could be a simple method for increasing the water repellence of copper mesh,and thereby be a great candidate for treating large-scale oily wastewater in harsh environments. | Yanling Tian Jiekai Feng Zexin Cai Jiaqi Chao Dawei Zhang Yuxiao Cui Faze Chen | 2021 | Journal of Bionic Engineering2021，18，4： | 1 |
| 19 | Kidney function change after transcatheter aortic valve replacement in patients with diabetes and/or hypertension显示文摘Aortic stenosis(AS)is a progressive heart valve disease occurring predominantly in older patients.According to a survey in a western country,the prevalence of AS is nearly 6.4%in patients over 75 years old(Carabello and Paulus,2009).Transcatheter aortic valve replacement(TAVR)is an alternative method for AS patients.Previous studies have described how up to 66%of TAVR patients have concomitant baseline kidney dysfunction(Ferro et al.,2015;Gargiulo et al.,2015).The majority of patients can benefit from the TAVR procedure with the recovery of kidney function. | Jiaqi FAN Changjie YU Kaida REN Wanbing LIN Stella NG Zexin CHEN Xinping LIN Lihan WANG Qifeng ZHU Yuxin HE Jubo JIANG Xianbao LIU Jian'an WANG | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，3： | 1 |
| 20 | Fully Decoupled Branch Energy Balancing Control Method for Modular Multilevel Matrix Converter Based on Sequence Circulating Components显示文摘The modular multilevel matrix converter(M3C)is a potential frequency converter for low-frequency AC transmission.However,capacitor voltage control of high-voltage and largecapacity M3C is more difficult,especially for voltage balancing between branches.To solve this problem,this paper defines sequence circulating components and theoretically analyzes the influence mechanism of different sequence circulating components on branch capacitor voltage.A fully decoupled branch energy balancing control method based on four groups of sequence circulating components is proposed.This method can control capacitor voltages of nine branches in horizontal,vertical and diagonal directions.Considering influences of both circulating current and voltage,a cross decoupled control is designed to improve control precision.Simulation results are taken from a low-frequency transmission system based on PSCAD/EMTDC,and effectiveness and precision of the proposed branch energy balancing control method are verified in the case of nonuniform parameters and an unbalanced power system. | Zexin Zhao Weijiang Chen Zhichang Yang Guoliang Zhao Bin Han Yunfei Xu Nianwen Xiang Shulai Wang | 2024 | CSEE Journal of Power and Energy Systems2024，10，1： | 0 |
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