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    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2术中神经电生理监测在单椎板入路选择性神经后根离断术中的作用显示文摘目的单椎板入路选择性神经后根离断术(SL-SDR)治疗痉挛性脑瘫完全依赖术中神经电生理监测结果。本研究旨在讨论SL-SDR术中肌电图判读对神经根选择和离断的影响及作用。方法回顾分析2016年5月至2019年3月在上海交通大学附属儿童医院神经外科采用改良神经电生理监测离断方案指导下SL-SDR治疗的痉挛性脑瘫患儿的临床资料,重点关注术中肌电图判读及其与术前临床表现的相关性,以及比较采用不同神经电生理监测离断方案解读术中肌电图时的神经后根选择差异。结果共纳入318例患儿,男性231例、女性87例,平均年龄5.9岁,32例为偏瘫、161例为双侧瘫、125例为四肢瘫。每例患儿有2~8组目标肌群(术前肌张力≥2级)。术中神经电生理监测结果显示,探测的21728枚神经小根[(68.3±8.2)枚/例]中6272枚(28.9%)与肛门括约肌相关,15456枚[(48.6±7.6)枚/例]与下肢肌群相关,其中,神经后根11009枚[(34.6±7.4)枚/例]。共有3370枚[(10.6±4.7)枚/例]符合改良神经后根离断方案,其中3061枚50%部分离断、309枚75%部分离断。术前粗大运动功能分级(GMFCS)分级Ⅰ~Ⅴ级的离断率(部分离断的神经后根数/下肢肌群相关神经后根数)分别为15.8%、22.3%、33.4%、41.8%和45.7%。75%部分离断的离断率随术前GMFCS分级的递增而增加,分别为1.5%、4.8%、8.5%、14.1%和15.2%。术后3周,2068组目标肌群肌张力显著降低[(1.7±0.5)级对(2.7±0.6)级]。术前GMFCS分级Ⅰ和Ⅱ级患儿采用传统离断方案约有20%的病例无法识别任何1枚约20%需离断的神经后根,而随着患儿术前GMFCS分级的递增,传统与改良方案离断的符合率逐步提高,分别为39.5%、41.3%、52.2%、54.1%和62.8%。结论由于SL-SDR完全依赖于术中肌电图判读,使得术中神经电生理监测显得至关重要。改良神经电生理监测离断方案指导下的SL-SDR可以安全、有效治疗痉挛性脑瘫。SL-SDR术中肌电图及其与临床表现相关的预后,可以使临床医师更好地理解此类患儿脊髓神经元环路的运作模式。Xiao B Constatntini S Browd SR Zhan Q Jiang W Mei R 詹琪佳(编译) 2020中国现代神经疾病杂志2020,20,4:4
3Leading Edge Film Cooling Enhancement for an Inlet Guide Vane with Fan-Shaped Holes显示文摘This paper describes the improvement of leading edge film cooling effectiveness for a turbine inlet guide vane by using fan-shaped film cooling holes. The modification details are presented in comparison with the base-line configuration of cylindrical holes. Numerical simulations were carried out for the base-line and modified configurations by using CFX, in which the κ-ε turbulence model and scalable wall function were chosen. Contours of adiabatic film cooling effectiveness on the blade surfaces and span-wise distributions of film cooling effectiveness downstream the rows of cooling holes interested for the different cooling configurations were compared and discussed. It is showed that with the use of fan-shaped cooling holes around the leading edge, the adiabatic film cooling effectiveness can be enhanced considerably. In comparison with the cylindrical film cooling holes, up to 40% coolant mass flow can be saved by using fan-shaped cooling holes to obtain the comparable film cooling effectiveness for the studied inlet guide vane.Jian-Jun LIU, Bai-Tao AN, Jie LIU and Zhan W Institute of Engineering Thermophysics, Chinese Academy of Sciences, P. O. Box 2706, Beijing 100190, China Professor,PhD 2010Journal of Thermal Science2010,19,6:3
4Reflectivity behavior of two dimensional ordered array of metallodielectric composite particles at large incidence angles 显示文摘ZHAN P LIU J B DONG W 2005Appl Phys Lett2005,86,05:1
5Immunomodulatory and antitumor effects of exopolysaeccharlde fraction (EPSF) from flcultivated Cordyceps sinensis fungus on tumor-bearing mice 显示文摘ZHANS W YANG J CHEN J 2004Biotechnol Appl Biochem2004,15,12:1
6Combining optional and microwave remote sensing for mapping energy fluxes in a semiarid watershed显示文摘 Zhan X Schmugge T J 1998R S Environ1998,64,:1
7Electrocardiographic characteristics in angiographically documented occlusion of the dominant left circumflex artery with acute inferior myocardial infarction: limitations of ST elevation III/II ratio and ST deviation in lateral limb leads 显示文摘Zhan ZQ Wang W Dang SY 2009J Electrocardiol2009,42,5:1
8The heavy ion cooler-storage-ring project (HIRFL- CSR) at Lanzhou显示文摘XIA J W ZHAN W L WEN B W 2002Nucl Instrum Methods Phys Res A2002,488,12:1
9Iterated unscented kalman filter for passive target tracking 显示文摘Zhan R H Wang J W 2007IEEE Transactions on Aero- space and Electronic Systems2007,43,3:1
10Long-term follow-up of mri-guided bilateral anterior capsulotomy in patients with refractory schizophrenia 显示文摘Liu W Hao Q Zhan S 2014Stereotact Funct Neurosurg2014,92,3:1
11Semiconductor@ Metal-Organic Framework Core-Shell Heterostnwtures: A Case of ZnO@ ZIF-8 Nanorods with Selective Photoeleetrochemical Response显示文摘Zhan W Kuang Q Zhou J etal 2013Journal of the American Chemical Society2013,135,5:1
12Temperature influences β-carotene production in recombinant Saccharomyces cerevisiae expressing carotenogenic genes from Phaffia rhodozyma显示文摘Shi F Zhan W Li Y 2014World Journal of Microbiology and Biotechnology2014,30,1:1
13Applied Field Mossbauer Study of Shape Anisotropy in Fe Nanowire Arrays显示文摘Zhan Q F He W Ma X 2004Appl Phys Lett2004,85,20:1
14Anomalous magnetic properties of cerium ions in the compounds CexR1-xFe2(R=Tb, Dy) 显示文摘 Zhan W S Chen D F Li Y X 1998J Phys Condens Matter1998,10,:1
15Performance of an unsaturated expansive soil slope subjected to artificial rainfall infiltration显示文摘NGCW W ZHAN L T BAO C G etal 2003Geotechnique2003,53,2:1
16Robust disturbance attenuation with stability for linear systems with norm-bounded nonlinear uncertainties显示文摘Wang L Y Zhan W 1996IEEE Transactions on Automatic Control1996,41,6:1
17Inhibition of PRL-3 gene expression in gastric cancer cell line SGC7901 via microRNA suppressed reduces peritoneal metastasis显示文摘Li Z Zhan W Wang Z 2006Biochem Biophys Res Commun2006,348,1:1
18Antibody-based inhibition of DKKI suppresses tumor-induced bone resorption and multiple myeloma growth in vivo显示文摘YACCOBY S LING W ZHAN F 2007Blood2007,109,5:1
19Pro- gress in HIRFL CSR显示文摘ZHAN W L XU H S XIAO G Q 2010Nuclear Physics A2010,834,69:1
20Thermally stable light- emitting polymers of substituted polyaoetylenes显示文摘YU G LIU Y Q ZHAN X W 2000Thin Solid Films2000,363,:1
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