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| 1 | Interaction of Restin with transcription factors显示文摘Restin, a member of melanoma-associated antigen superfamily gene, was first cloned from differentiated leukemia cell induced by all trans-retinoic acid, and was able to inhibit cell proliferation, but the molecular mechanism was not clear. Since Restin was localized in cell nucleus, and its homolog member, Necdin (neuronal growth suppressor factor), could interact with transcription factors p53 and E2F1, we proposed that Restin might also function as Necdin through interacting with some transcription factors. In this study, transcription factors p53, AP1, ATFs and E2Fs were cloned and used in the mammalian two-hybrid system to identify their in- teraction with Restin. The results showed that only ATF3 had a strong interaction with Restin. It is interesting to know that ATF3 was an important transcription factor for G1 cell cycle initiation in physiological stress response. It was possible that the inhibition of cell proliferation by Restin might be related with the inhibition of ATF3 activity. | WU Yousheng LU Fan QI Yinxin WANG Ruihua ZHANG Jian LU Zifan ZHAO Zhongliang | 2005 | Science China(Life Sciences)2005，48，3： | 5 |
| 2 | Genome shuffling leads to rapid phenotypic improvement in bacteria显示文摘 | ZHANG Yinxin PERRY K VINCI V A | 2002 | Nature2002，415，： | 1 |
| 3 | Human activity during the late Pleistocene in the Lop Nur region, northwest China: Evidence from a buried stone artifact显示文摘The Lop Nur region, in the east part of Tarim Basin, was an important transportation junction between west and east,north and south Eurasia. However, previous studies on prehistoric human activity have concentrated mostly on the Bronze Age,whereas that during the Stone Age remains largely unresearched. Here, we present a new direct evidence of human activity in the late Pleistocene, recorded on a grinding stone buried in a lacustrine sediment section of the Lop Nur region. The grain size distribution of the sediment section indicates that the site was probably in the center of a lake with weak hydrodynamic environment. Therefore, the stone artifact can only be carried to here by people instead of river and it was never move as soon as left here. Results of radiocarbon dating, the evident stratigraphic relations between the stone artifact and the sedimentary formation, indicate that the human activity could extend to approximately 13 ka BP. Furthermore, the results of starch-grain and use-wear analyses suggest that ancient humans gathered seeds of Triticeae, roots, and tubers and used the grinding stone to simply process selected plant as plant foodstuffs during this period. It implies that the environmental conditions in the river delta of the Lop Nur were inhabitable during the late Pleistocene. | Kangkang LI Xiaoguang QIN Xiaoyan YANG Bing XU Lei ZHANG Guijin MU Dong WEI Chunxue WANG Yong WU Xiaohong TIAN Yongchong LIN Wen LI Jiaqi LIU Yinxin JIAO | 2018 | Science China Earth Sciences2018，61，11： | 1 |
| 4 | Performance and stability of yield in response to plant density,year and location in maize hybrids of Northwest China显示文摘Identifying desirable genotypes with the best performance in diverse environments is a perpetual aim of plant breeding,and the interaction between genotype and environment(G×E)always plays a key role.This study was conducted to elucidate the genetic behaviour of different hybrid combinations at various densities in diverse environments.According to a line×tester design,32 hybrid combinations were obtained from 16 inbred individuals crossed with two testers and planted at three locations at three density levels(45,000,67,500 and 90,000 plants ha-1)during 2014-2017.Genotype(G),environment(E)and the interaction of genotype and environment(G×E)significantly affected grain yield at different densities.Increasing planting density enhanced grain yield and improved the efficiency of germplasm screening,where the effect of location on grain yield at different densities was larger than that of year and the GCA was larger than the SCA.Finally,four inbred lines(KB102,KB081,KA105,and KB106)with a high GCA,environmental adaptability,and several combinations using them as parents have been approved in ShannXi Province and National of China.In conclusion,the evaluation of combining ability at multiple densities and locations can effectively screen inbred lines and improve breeding efficiency. | Yuan Dong Zhiqian Feng Ting Li Ali Farhan Xiaokang Tian Yonghui Lao Yinxin Duan Leiyong Si Xinghua Zhang Jiquan Xue Shutu Xu | 2022 | Technology in Agronomy2022，2，1： | 1 |
| 5 | miR-92a is a critical regulator of the apoptosis pathway in glioblastomawith inverse expression of BCL2L11显示文摘 | Huanjiang Niu Kun Wang Anling Zhang Shuxu Yang Zhengfei Song Wei Wang Cong Qian Xinwei Li Yinxin Zhu Yirong Wang | 2012 | Oncology Reports2012，，5： | 1 |
| 6 | Effects of dynamical cure and compatibilization on the morphology and properties of the PP / epoxy blends显示文摘 | Jiang Xueliang Sun Kang Zhang Yinxin | 2007 | Express Polymer Letters2007，1，5： | 1 |
| 7 | Control of cholesterol biosynthesis, uptake and storage in hepatocytes by Cideb显示文摘 | John Zhong Li Yao Lei Yue Wang Yinxin Zhang Jing Ye Xiayu Xia Xianming Pan Peng Li | 2010 | BBA - Molecular and Cell Biology of Lipids2010，，5： | 1 |
| 8 | Acute myocardial infarction following 5-fluorouracil treatment显示文摘5-Fluorouracil(5-FU)is an antimetabolite chemotherapeutic agent that is US Food and Drug Administration(FDA)indicated for use in a variety of neoplasms and is a staple agent in many chemotherapeutic regimens.An important adverse effect of 5-FU is cardiotoxicity.There is a wide spectrum of clinical presentation of 5-FU cardiotoxicity from asymptomatic electrocardiogram(ECG)changes to myocardial infarction that clinicians must be aware of when caring for patients receiving this agent. | Jose Rivas Rios Melissa Oye Yinxin Zhang Andrea Rivas Fabiana Rollini Khadeeja Esmail | 2023 | Journal of Geriatric Cardiology2023，20，7： | 0 |
| 9 | Dynamic interconnection component using wireless infrared technology显示文摘An efficient dynamic interconnection model using wireless infrared technology and the theory of optical interconnections was constructed to design a dual-channel interconnection component.There were three conditions between the rotating optical field and the stationary optical field:end separation,angle misalignment and lateral mis-alignment.The calculation formulas were given for these three conditions.A dual-channel optical interconnection com-ponent was designed based on the dynamic interconnection model and the data transmission rate of the component was measured.The experimental result showed that the dual-channel optical interconnection component could transmit optical signals across the rotating interface.The maximum transmission rate can reach 2.14 Mb/s. | JIA Dagong WANG Guanghui ZHANG Yimo ZHANG Yinxin JING Wencai ZHOU Ge | 2007 | Frontiers of Electrical and Electronic Engineering in China2007，2，3： | 0 |
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