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| 1 | Sevoflurane exposure in 7-day-old rats affects neurogenesis, neurodegeneration and neurocognitive function显示文摘Objective Sevoflurane is widely used in pediatric anesthesia and former studies showed that it causes neurodegeneration in the developing brain. The present study was carried out to investigate the effects of sevoflurane on neurogenesis, neurodegeneration and behavior. Methods We administered 5-bromodeoxyuridine, an S-phase marker, before, during, and after 4 h of sevoflurane given to rats on postnatal day 7 to assess dentate gyrus progenitor proliferation and Fluoro-Jade staining for degeneration. Spatial reference memory was tested 2 and 6 weeks after anesthesia. Results Sevoflurane decreased progenitor proliferation and increased cell death until at least 4 days after anesthesia. Spatial reference memory was not affected at 2 weeks but was affected at 6 weeks after sevoflurane administration. Conclusion Sevoflurane reduces neurogenesis and increases the death of progenitor cells in developing brain. This might mediate the lateonset neurocognitive outcome after sevoflurane application. | Fang Fang Zhanggang Xue Jing Cang | 2012 | Neuroscience Bulletin2012，28，5： | 12 |
| 2 | Expert Recommendations for Tracheal Intubation in Critically Ill Patients with Noval Coronavirus Disease 2019显示文摘Coronavirus Disease 2019(COVID-19),caused by a novel coronavirus(SARS-Co V-2),is a highly contagious disease.It firstly appeared in Wuhan,Hubei province of China in December 2019.During the next two months,it moved rapidly throughout China.Most of the infected patients have mild symptoms including fever,fatigue and cough,but in severe cases,patients can progress rapidly and develop into acute respiratory distress syndrome,septic shock,metabolic acidosis and coagulopathy.The new coronavirus was reported to spread via droplets,contact and natural aerosols from human to human.Therefore,aerosol-producing procedures such as endotracheal intubation may put the anesthesiologists at high risk of nosocomial infections.In fact,SARSCo V-2 infection of anesthesiologists after endotracheal intubation for confirmed COVID-19 patients have been reported in hospitals in Wuhan.The expert panel of airway management in Chinese Society of Anaesthesiology has deliberated and drafted this recommendation,by which we hope to guide the performance of endotracheal intubation by frontline anesthesiologists and critical care physicians.During the airway management,enhanced droplet/airborne personal protective equitment(PPE)should be applied to the health care providers.A good airway assessment before airway intervention is of vital importance.For patients with normal airway,awake intubation should be avoided,and modified rapid sequence induction is strongly recommended.Sufficient muscle relaxant should be assured before intubation.For patients with difficult airway,good preparation of airway devices and detailed intubation plans should be made. | Mingzhang Zuo Yuguang Huang Wuhua Ma Zhanggang Xue Jiaqiang Zhang Yahong Gong Lu Che 无 | 2020 | Chinese Medical Sciences Journal2020，35，2： | 7 |
| 3 | Enhanced Recovery After Surgery (ERAS) Program Attenuates Stress and Accelerates Recovery in Patients After Radical Resection for Colorectal Cancer: A Prospective Randomized Controlled Trial显示文摘 | Li Ren Dexiang Zhu Ye Wei Xiangou Pan Li Liang Jianmin Xu Yunshi Zhong Zhanggang Xue Ling Jin Shaokang Zhan Weixin Niu Xinyu Qin Zhaohan Wu Zhaoguang Wu | 2012 | World Journal of Surgery2012，，2： | 1 |
| 4 | Research on antierror performance of speed and flux estimator for induction motor using robust reduced-order EKF显示文摘 | Yin Zhanggang Zhao Chang Liu Jing | 2013 | IEEE Transactions on Industrial Informatics2013，9，2： | 1 |
| 5 | Study on ferric chloride etchant etching ability 显示文摘 | ZhangGang(张刚) YuMingyao(于明瑶) KangYanhong(康艳红) | 2012 | 辽宁化工2012，41，12： | 1 |
| 6 | The in vitro effect of desflurane preconditioning on endothelial adhesion molecules and mRNA expression显示文摘 | Biao Z Zhanggang X Hao J | 2005 | Anesth Analg2005，100，4： | 1 |
| 7 | Sevoflurane/propofol coadministration provides better recovery than sevoflurane in combined general/epidural anesthesia: a randomized clinical trial显示文摘 | Chao Liang Ming Ding Fang Du Jing Cang Zhanggang Xue | 2014 | Journal of Anesthesia2014，，5： | 1 |
| 8 | ModifiGcationofsiliconerubberwithcarbonnanotubes显示文摘 | YaoLingjiang ZhangGang ChenXiaohua etal | 2004 | JourGnalofFunctionalMaterials2004，35，1： | 1 |
| 9 | The in vitro effect of desflurane preconditioning on endothelial adhesion molecules and mRNA expression 显示文摘 | BIAO Z ZHANGGANG X HAO J | 2005 | Anesth Analg2005，100，4： | 1 |
| 10 | STUDY ON THE COUPLED ELECTROMECHANICAL DYNAMICS OF ROTOR SYSTEM EQUIPPED WITH MAGNETIC BEARINGS显示文摘The influences of thrust magnetic bearing and journal tilt on dynamic characteristics of rotor system are studied mainly.The outcome shows that the influences of coupling effects of thrust magnetic bearing and tilt of journal on critical rotational speeds of system are very large, and the stability of system reduces greatly.That shows it is important that the influence of coupling effects of thrust and radial magnetic bearings due to the rotor tilting must be considered in the study of rotor-magnetic bearings system dynamic characteristics, and also shows it is important that the rotor is mounted and debugged in ideal alignment of magnetic bearings. | ZhangGang ZhangJiansheng LiSongsheng YangXinzhou WuJianfeng WangXiping YuLie XieYoubai | 2004 | Chinese Journal of Mechanical Engineering2004，17，1： | 1 |
| 11 | Purification and Characterization of Cold-active α-Amylase Excreted by A Strain of Marine Cold-adaptive Penicillia显示文摘The filamentous fungi from the Huanghai sea sludge were screened according to their ability to produce cold-active α-amylase. The strain with the highest amylase activity was identified as Penicillium species. The α-amylase purified by ammonium sulphate precipitation and column chromatography on DEAE-sepharose and sephadex G-100 shows a molecular weight of about 55000 and a pI of 4.38. The enzyme is stable in a pH range of 5.5—8.0 and has a maximum activity at pH 6.0. Compared with the α-amylase from mesophiles and thermophiles, the cold-active enzyme shows a high enzyme activity at lower temperatures and a high sensitivity at temperatures higher than 50 ℃. The optimal temperature is 40 ℃ and the activity decreases dramatically at temperatures above 50 ℃. Ca 2+ shows a significant effect on maintaining the structure and the activity of the enzyme. EDTA and Cu 2+ are its inhibitors. The products from the hydrolysis of soluble starch with the cold-active enzyme are maltose and other oligosaccharides. | WANGTian-hong ZHANGGang HOUYun-hua | 2004 | Chemical Research in Chinese Universities2004，20，1： | 0 |
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