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| 1 | Spacecraft rendezvous trajectory safety quantitative performance index eliminating probability dilution显示文摘In view of the probability dilution problem of the existing quantitative indexes of rendezvous trajectory safety performance using collision probability,this paper proposes a new quantitative index of rendezvous trajectory safety performance by well combining collision probability with warning threshold.The proposed new index increases monotonously as the position errors of the chaser spacecraft increase,therefore it can effectively overcome the problems of the reduction in the largest performance value and the advancement in the most dangerous time induced by the probability dilution.The proposed new index is applied to the safety design of close range rendezvous missions.The mission’s safety requirements for initial navigation precision and the safe region of initial and final keeping points’positions with a certain navigation precision are analyzed,and several valuable conclusions about the relation between position navigation precision and velocity navigation precision as well as the relation between keeping points’positions and navigation precision are obtained. | SUN ZhenJiang LUO YaZhong NIU ZhiYong | 2014 | Science China(Technological Sciences)2014，57，6： | 4 |
| 2 | On the criteria of instability for electrochemical systems显示文摘 | Li Zelin Ren Bin Niu Zhenjiang | 2002 | Chin J Chem2002，20，7： | 1 |
| 3 | In situ monitoring of potential oscillations in the reduction of IO3^- by electrochemical quartz crystal microbalance显示文摘 | Li Zelin Niu Zhenjiang Wu Tinghua | 2003 | Electrochem Commun2003，5，4： | 1 |
| 4 | Clinical significance of serum IgM and IgG levels in COVID-19 patients in Hubei Province,China显示文摘Background:There have been many studies about coronavirus disease 2019(COVID-19),but the clinical signifi-cance of quantitative serum severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2)-specific IgM and IgG levels of COVID-19 patients have not been exhaustively analyzed.We aimed to investigate the time profiles of these IgM/IgG levels in COVID-19 patients and their correlations with clinical features.Methods:A multicenter clinical study was conducted from February 20 to March 52020.It involved 179 COVID-19 patients(108 males and 71 females)from five hospitals in Huangshi in Hubei Province,China.To detect SARS-CoV-2-specific IgM/IgG,quantitative antibody assays(two-step indirect immunoassays with direct chemilu-minescence technology)based on the nucleocapsid protein(NP)and spike protein 1(S1)were used.For normally distributed data,means were compared using the t-test,��2-test,or exact probability method.For categorical data,medians were compared using Mann-Whitney U test.Results:The median age was 57(44-69)years(58[38-69]for males and 57[49-68]for females).The median duration of positive nucleic acid test was 22.32(17.34-27.43)days.The mortality rate was relatively low(3/179,1.68%).Serum SARS-CoV-2-specific IgG was detected around week 1 after illness onset,gradually increased until peaking in weeks 4 and 5,and then declined.Serum IgM peaked in weeks 2 and 3,then gradually declined and returned to its normal range by week 7 in all patients.Notably,children had milder respiratory symptoms with lower SARS-CoV-2-specific IgM/IgG levels.The duration of positive nucleic acid test in the chronic obstructive pulmonary disease(COPD)group was 30.36(18.99-34.76)days,which was significantly longer than that in the non-COPD group(21.52[16.75-26.51]days;P=0.025).The peak serum SARS-CoV-2-specific IgG was sig-nificantly positively correlated with the duration of positive nucleic acid test.The incidence rate of severe and critical cases in the IgM hi group(using the median IgM level of 29.95 AU/mL as the cutofffor grouping)was about 38.0%(19/50),which was twice as much as that in the IgM lo group(18.4%;9/49).The patients with positive chest imaging and lymphocytopenia(<1×10^(9)/L)had a higher SARS-CoV-2-specific IgM level.Conclusions: Quantitative SARS-CoV-2-specific IgM and IgG levels are helpful for the diagnosis, severity classifi- cation, and management of COVID-19 patients, and they should be monitored in each stage of this disease. | Zhenjiang Bai Qing Li Qinghui Chen Changming Niu Yu Wei Hanpeng Huang Wei Zhao Nian Chen Xin Yao Qiang Zhang Chuanyong Mu Jian Feng Chuanlong Zhu Zhuo Li Ming Ding Binhui Feng Chaochao Jin Xiang Lu Yi Yang Shuiyan Wu Xiaochen Shu Haibo Qiu YingZi Huang | 2022 | Journal of Intensive Medicine2022，2，1： | 0 |
| 5 | αExtractor: a system for automatic extraction of chemical information from biomedical literature显示文摘Dear Editor,Great progress has been made using artificial intelligence(AI) techniques in learning knowledge from biomedical databases in recent years, revolutionizing the study of many fields, such as protein structure prediction and protein design(Madani et al., 2023). However, there is massive biomedical knowledge not curated in the form of structured data but hidden in primary scientific literature. | Jiacheng Xiong Xiaohong Liu Zhaojun Li Hongzhong Xiao Guangchao Wang Zhenjiang Niu Chaoyuan Fei Feisheng Zhong Gang Wang Wei Zhang Zunyun Fu Zhiguo Liu Kaixian Chen Hualiang Jiang Mingyue Zheng | 2024 | Science China(Life Sciences)2024，67，3： | 0 |
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