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| 1 | Multifunctional lymph-targeted platform based Mn@mSiO2 nanocomposites: Combining PFOB dual-mode imaging and DOX for cancer diagnose treatment on for and显示文摘 | Tian Liu Guangyu Wu Jiejun Cheng Qing Lu Yanjie Yao Zhenjing Liu Dongchen Zhu Juan Zhou Jianrong Xu Jun Zhu Dannong He | 2016 | Nano Research2016，9，2： | 11 |
| 2 | Maize MS2 encodes an ATP-binding cassette transporter that is essential for anther development显示文摘The anther cuticle and pollen exine play a critical role in male gametophyte development. The sporopollenin precursors and cuticular lipid monomers are transported to the surface of the microspores and the epidermis by lipid transport proteins(LTPs) and ATP-binding cassette G(ABCG) transporters for the formation of the pollen wall and anther cuticle, respectively. However, the function of ABCG transporters in maize anther development is unclear. Here, we cloned the MS2 gene from the maize male sterile2 mutant using map-based cloning and determined that it encodes an ABCG transporter. MS2 protein was experimentally confirmed to be located on the cell membrane. The quantitative real-time PCR(qRT-PCR)results showed that MS2 was ubiquitously expressed in all vegetative and reproductive tissues, whereas a high transcriptional level of MS2 was observed in anthers, especially at the young microspore stage. Gas chromatography-mass spectrometry(GC–MS) analysis showed decreased accumulation of cutin and wax components in ms2 anthers, indicating that MS2 plays a role in the transport of lipid molecules to anther cuticle and pollen exine. To our knowledge, MS2 is the first reported ABCG transporter gene that participates in anther development in maize. | Qilong Xu Li Yang Dan Kang Zhenjing Ren Yunjun Liu | 2021 | The Crop Journal2021，9，6： | 4 |
| 3 | Identification of Major Locus Bph35 Resistance to Brown Planthopper in Rice显示文摘An introgression line RBPH660,derived from wild rice Oryza rufipogon,showed stable resistance to brown planthopper(BPH).Segregation analysis indicated BPH resistance of RBPH660 was controlled by multiple genes/QTLs.By using the bulked segregant analysis(BSA)-seq method,two genomic regions harboring QTLs resistance to BPH were identified from 1.20 to 16.70 Mb on chromosome 4 and from 10.20 to 12.60 Mb on chromosome 9 in RBPH660,respectively.A major resistance locus,designated as Bph35 accounting for 51.27%of the phenotypic variation with a LOD score of 42.51,was mapped to the candidate region of chromosome 4 between In Del(insertion-deletion)markers PSM16 and R4 M13.For fine mapping of Bph35,one simple sequence repeat and three newly developed In Del markers were used to screen the recombinants.Finally,the Bph35 locus was delimited in the region from 6.28 to 6.93 Mb and there were 18 predicted protein-encoding genes with a total of 114 non-synonymous single nucleotide polymorphism(SNP)variant sites between the resistant and susceptible parents.Out of these genes,Os04 g0193950,encoding a putative NB-ARC(nucleotidebinding adaptor shared by APAF-1,R proteins and CED-4)and LRR(leucine-rich repeat)domain protein with nine non-synonymous SNP substitutions in its coding sequence regions,might be the candidate gene for Bph35.These findings would facilitate the map-based cloning of the Bph35 gene and development of resistant varieties against BPH in rice. | ZHANG Yuexiong QIN Gang MA Qianqian WEI Minyi YANG Xinghai MA Zengfeng LIANG Haifu LIU Chi LI Zhenjing LIU Fang HUANG Dahui LI Rongbai | 2020 | Rice science2020，27，3： | 3 |
| 4 | THE CO-RELATIONSHIP BETWEEN NEIGUAN POINT AND THE HEART AND REGULATION OF AMYGDALOID NUCLEI显示文摘In this present study, the ruodel of the rabbit with acute myocardial ischemia(AMI) was used to explore mechanisms of interrelation hetween Neiguan acupoint (PC 6) of the Peri-cardium Meridian and the heart hy employing physiological and morphologicaI methods. It wasdemonstrated that electroacupuncture (EA) at Neiguan (PC 6 ) couId raise the eIectrical excitahility ofischemic myocardium, lessen the dispersity of recovery excitability, correct the disorder of electricalactivity; protect myocardiac glycogen and phosphorylase and alleviate their depletion, increase contentof ribonuclei acid (RNA ), etc., indicating that EA could help oxidative rnetaholism carry out normal-Iy and irnProve nutritional state of the ischemic myocardiurn. The key point of EA action is probablyregulates the coronary microclrculation of heart and reclistributes myocardial blood flow. Studies withalkaline phosphatase (ALP ), Mg2--ATPase and ABS casting of the Ieft coronary artery showed thatafter EA the number and the Iength | Cao Qingshu, Wen Shen, Liu Junling, Han Zhenjing, Chen ShupingInstitute of Acupuncture and Moxibustion , China Academy of TCM, Beijing 100700 , China | 1995 | World Journal of Acupuncture-Moxibustion1995，5，2： | 1 |
| 5 | Heat and mass transfer model optimization and annual energy efficiency analysis for energy recovery indirect evaporative cooling显示文摘Indirect evaporative cooling(IEC)is a kind of high efficiency,energy-saving and environmental protection cooling technology,which has been widely used in data centers and other fields in recent years.In this paper,the optimized two-dimensional non-condensation state model of indirect evaporative cooling was proposed.Meanwhile the computer program was updated to solve the developed mathematical model under variable fresh air conditions.The optimized model was verified by the experimental data,and the maximum deviation was only 4.6%.Based on the modified model and the annual hourly meteorological parameters in Tianjin,China,it was analyzed the optimal heat transfer area of IEC used as fresh air pre-cooling unit under various air volumes to provide references for system design and equipment selection.Finally,taking an IEC-primary return air conditioning system of a gymnasium as an example,the hourly energy-saving effect of whole year was simulated by the developed IEC model.The simulation results showed that IEC could control the fresh air temperature below 27℃ and the moisture content below 18 g/kg throughout the year,and undertook 102.6% of the total fresh air cooling load.The findings are useful in future system optimization and design of IEC equipment. | Qilong Liu Chunmei Guo Zhenjing Wu Yuwen You Yan Li | 2022 | Building Simulation2022，15，7： | 0 |
| 6 | Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia显示文摘Deltamethrin(DEL),a commonly used pyrethroid pesticide,results in higher reactive oxygen species(ROS)levels in aquatic animals,which consequently unbalance the redox state.Phlorizin(PHL)is a flavonoid and a natural product promising to prevent or reduce pesticide-induced oxidative stress.Artemia is a micro-crustacean widely used in marine hatcheries and an experimental aquatic organism for environmental toxicology research.This research aimed to evaluate the toxicity of DEL on Artemia and the antioxidative effect of PHL against the toxicity.Results show that 0.08-mg/mL PHL exerted its antioxidative effects on hatching percentage of the cysts in 24-h incubation and on body length and survival rate of Artemia in 12-d culture.After 12-d culture,12-,24-,and 36-h DEL exposure showed significant drops in SOD,CAT,and GSH-Px enzyme activities,and significant increases in ROS and malondialdehyde(MDA)levels in Artemia(P<0.05).On the contrary,0.08-mg/mL PHL application improved the enzyme activities and decreased the ROS and MDA levels(P<0.05).Moreover,0.08-mg/mL PHL significantly increased mRNA expression levels of Cu/Zn SOD,CAT,GST,HO-1,NQO1,and Nrf2,and decreased mRNA expression level of Keap1 in the DEL-exposed Artemia(P<0.05).Therefore,DEL is toxic to Artemia,while PHL alleviates DEL-induced oxidative damage by possibly regulating the Nrf2signaling pathway.This study provided a theoretical basis for PHL to reduce pesticide-induced toxicity in aquatic animals. | Dandan MA Qingli ZHOU Liying SUI Qingbin GUO Huanhuan LIU Honghe LIANG Zhenjing LI Zhongna SANG | 2024 | Journal of Oceanology and Limnology2024，42，1： | 0 |
| 7 | Synthesis of hexagonal boron nitrides by chemical vapor deposition and their use as single photon emitters显示文摘Two-dimensional(2D)hexagonal boron nitride(hBN),due to its extraordinary thermal,chemical,and optical properties,has arisen as an enticing material for the research community to explore for various applications,including the use of site defects in hBN as single photon emitters(SPEs).In this review,we systematically summarize recent advanced strategies towards the controllable synthesis of 2D hBN using chemical vapor deposition,towards a full control of the domain size,orientation,morphology,layer number,and stacking order,etc.Moreover,we review the underlying mechanisms for single photon emission(SPE)in hBN and methods to selectively generate and tune the SPEs.Defects(e.g.,carbon substituted defects)are discussed for the potential use as emission sites.We finally give an outlook of future challenges and opportunities on desirable hBN synthesis and further investigation of SPEs in hBN,targeting to utilize hBN as single photon emitters in an industrial scale. | Hongwei Liu Chae Young You Jingwei Li Patrick Ryan Galligan Jiawen You Zhenjing Liu Yuting Cai Zhengtang Luo | 2021 | Nano Materials Science2021，3，3： | 0 |
| 8 | Quaternary Sporopollen Records and Environmental Evolution in the Dalangtan of Qaidam Basin显示文摘Since the Quaternary,very thick lacustrine sediments have been deposited in Dalangtan of Qaidam Basin.Based on a study of high-resolution sporopollen analysis on the Dalangtan ZK06 drilling,and paleomagnetic | YANG Zhenjing YANG Qinghua ZHEN Mianping HOU Xianhua BI Zhiwei LIU Linjing | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 0 |
| 9 | Graphene foam/hydrogel scaffolds for regeneration of peripheral nerve using ADSCs in a diabetic mouse model显示文摘The functional recovery of peripheral nerve injury(PNI)is unsatisfactory,whereas diabetes mellitus(DM)and its related complications further attenuate the restoration of diabetic PNI(DPNI).Adipose-derived stem cells(ADSCs)are promising candidates for treatment of DPNI due to their abundant source,excellent differentiation and paracrine ability.Our results showed that ADSCs remarkably enhanced the proliferation and migration of Schwann cells and endothelial cells,and tube formation.Mechanistically,ADSCs could regulate Nrf2/HO-1,NF-κB and PI3K/AKT/mTOR signaling pathways,showing multiple functions in reducing oxidative stress and inflammation,and regulating cell metabolism,growth,survival,proliferation,angiogenesis,differentiation of Schwann cell and myelin formation.In current study,novel graphene foam(GF)/hydrogel-based scaffold was developed to deliver ADSCs for treatment of DPNI.GF/hydrogel scaffold exhibited excellent mechanical strength,suitable porous network,superior electrical conductivity,and good biocompatibility.In vitro results revealed that GF/hydrogel scaffold could obviously accelerate proliferation of Schwann cells.Moreover,in vivo experiments demonstrated that ADSCs-loaded GF/hydrogel scaffold significantly promoted the recovery of DPNI and inhibited the atrophy of targeted muscles,thus providing a novel and attractive therapeutic approach for DPNI patients. | Qun Huang Yuting Cai Xinrui Yang Weimin Li Hongji Pu Zhenjing Liu Hongwei Liu Mohsen Tamtaji Feng Xu Liyuan Sheng Tae-Hyung Kim Shiqing Zhao Dazhi Sun Jinbao Qin Zhengtang Luo Xinwu Lu | 2022 | Nano Research2022，15，4： | 0 |
| 10 | Mechanical behavior and semiempirical force model of aerospace aluminum alloy milling using nano biological lubricant显示文摘Aerospace aluminum alloy is the most used structural material for rockets,aircraft,spacecraft,and space stations.The deterioration of surface integrity of dry machining and the insufficient heat transfer capacity of minimal quantity lubrication have become the bottleneck of lubrication and heat dissipation of aerospace aluminum alloy.However,the excellent thermal conductivity and tribological properties of nanofluids are expected to fill this gap.The traditional milling force models are mainly based on empirical models and finite element simulations,which are insufficient to guide industrial manufacturing.In this study,the milling force of the integral end milling cutter is deduced by force analysis of the milling cutter element and numerical simulation.The instantaneous milling force model of the integral end milling cutter is established under the condition of dry and nanofluid minimal quantity lubrication(NMQL)based on the dual mechanism of the shear effect on the rake face of the milling cutter and the plow cutting effect on the flank surface.A single factor experiment is designed to introduce NMQL and the milling feed factor into the instantaneous milling force coefficient.The average absolute errors in the prediction of milling forces for the NMQL are 13.3%,2.3%,and 7.6%in the x-,y-,and z-direction,respectively.Compared with the milling forces obtained by dry milling,those by NMQL decrease by 21.4%,17.7%,and 18.5%in the x-,y-,and z-direction,respectively. | Zhenjing DUAN Changhe LI Yanbin ZHANG Min YANG Teng GAO Xin LIU Runze LI Zafar SAID Sujan DEBNATH Shubham SHARMA | 2023 | Frontiers of Mechanical Engineering2023，18，1： | 0 |
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