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| 1 | Microstructure and mechanical properties of Al-Mg-Mn alloy with erbium显示文摘The effect of trace element Er on the microstructure and properties of Al-6Mg-0.7Mn-0.1Cr-0.15Ti alloy was investigated. The results show that the ultimate room-temperature and high-temperature strength sof the alloy have not increased obviously with the addition of erbium, but the uniform elongation of alloys decreases from 9% and 27.5% to 5.5% and 22.5%, respectively. The reason is that the addition of Er will first react with Ti, Cr to form Al20Ti2Er, Al8Cr4Er phases. The precipitation strengthening makes up the weakening of grain refinement strengthening. During deformation, the primary Al(TiCr)Er and Al3Er particles fracture first and act as the microcrack sources because of the stress concentration. | Wang, Xudong Lin, Shuangping Yang, Junjun Tang, Zhenlei Nie, Zuoren | 2012 | Rare Metals2012，31，3： | 6 |
| 2 | Intra-articular delivery of tetramethylpyrazine microspheres with enhanced articular cavity retention for treating osteoarthritis显示文摘Tetramethylpyrazine(TMP) is a traditional Chinese herbal medicine with strong antiinflammatory and cartilage protection activities, and thus a promising candidate for treating osteoarthritis. However, TMP is rapidly cleared from the joint cavity after intra-articular injection and requires multiple injections to maintain efficacy. The aim of this study was to encapsulate TMP into poly(lactic-co-glycolic acid)(PLGA) microspheres to enhance the TMP retention in the joint, reducing injection frequencies and decreasing dosage. TMP microspheres were prepared by emulsion/solvent evaporation method. The intra-articular retention of the drug was assessed by detecting the drug concentration distributed in the joint tissue at different time points. The therapeutic effect of TMP microspheres was evaluated by the swelling of knee joints and histologic analysis in papain-induced OA rat model. The prepared freezedried microspheres with a particle size of about 10 μm can effectively prolong the retention time of the drug in the articular cavity to 30 d, which is 4.7 times that of the TMP solution.Intra-articular injection of TMP microspheres efficiently relieved inflammatory symptoms,improved joint lesions and decreased the depletion of proteoglycan. In conclusion, intraarticular injection of TMP loaded microspheres was a promising therapeutic method in the treatment of OA. | Xiuping Zhang Yang Shi Zhiyue Zhang Zhenlei Yang Guihua Huang | 2018 | Asian Journal of Pharmaceutical Sciences2018，13，3： | 2 |
| 3 | Determination of trichothecenes A (T-2 toxin, HT-2 toxin, and diacetoxyscirpenol) in the tissues of broilers using liquid chromatography coupled to tandem mass spectrometry显示文摘 | Lingchen Yang Zhiyong Zhao Aibo Wu Yifeng Deng Zhenlei Zhou Jianpeng Zhang Jiafa Hou | 2013 | Journal of Chromatography B2013，，： | 1 |
| 4 | Effective parameterizations of three nonwetting phase relative permeability models显示文摘 | Yang Zhenlei Mohanty Binayak P | 2015 | Water Resources Research2015，，： | 1 |
| 5 | An energy-based low-cycle fatigue life evaluation method considering anisotropy of single crystal superalloys显示文摘The crystal orientation significantly affects the low-cycle fatigue (LCF) propertiesof single crystal (SC) superalloys. However, the orientation-dependent LCF life model withprecise mechanisms and strong applicability is still lacking. This investigation aims at establishing an energy-based LCF life evaluation method that could consider the orientation effect. First,the influencing factors of anisotropy were identified through the literature review. Secondly, themultiaxial formula of the Ramberg-Osgood (ReO) equation was established to describe theanisotropic cyclic deformation characteristics. Furthermore, the strain energy density of SC superalloys was determined based on this equation, and the effective strain energy density wasintroduced to account for the effect of orientation. Finally, the energy-based method was validated by its application to several SC superalloys. Results showed that the crystallographicorientation with a lower Young’s modulus usually exhibits better LCF resistance. This phenomenon could be attributed to the different values of strain energy density dissipated in one cycle.The multiaxial ReO relationship could capture the anisotropic cyclic deformation response ofDD6. Compared with the classical methods, the energy-based model is favored by its precisemechanism and strong applicability. And it also exhibited better prediction accuracy. Most datapoints of different crystallographic orientations lay within the 3 error band. | Tianxiao Sui Duoqi Shi Yongsheng Fan Zhenlei Li Xiaoguang Yang | 2022 | Propulsion and Power Research2022，11，2： | 0 |
| 6 | A multi-scale framework for life reduction assessment of turbine blade caused by microstructural degradation显示文摘The prolonged thermal exposure with centrifugal load results in microstructural degradation,which ultimately leads to a reduction in the fatigue and creep resistance of the turbine blades.The present work proposes a multi-scale framework to estimate the life reduction of turbine blades,which combines a microstructural degradation model,a two-phase constitutive model,and a microstructure-dependent fatigue and creep life reduction model.The framework with multi-scale models is validated by a Single Crystal(SC)Ni-based superalloy at the microstructural length-scale and is then applied to calculate the microstructural degradation and the fatigue and creep life reduction of turbine blades under two specific service conditions.The simulation results and quantitative analysis show that the microstructural degradation and fatigue and creep life reduction of the turbine blade are heavily influenced by the variations in the proportion of the intermediate state,namely,the maximum rotor speed status,in the two specific service conditions.The intermediate state accelerates the microstructural degradation and leads to a reduction of the life,especially the effective fatigue life reserve due to the higher temperature and rotational speed than that of the 93%maximum rotor speed status marked as the reference state.The proposed multi-scale framework provides a capable approach to analyze the reduction of the fatigue and creep life for turbine blade induced by microstructural degradation,which can assist to determine a reasonable Time Between Overhaul(TBO)of the engine. | Xiaoguang YANG Menglei WANG Duoqi SHI Zhenlei LI Yongsheng FAN | 2024 | Chinese Journal of Aeronautics2024，37，1： | 0 |
| 7 | 3-20 Heavy Ion Induced Single Event Upset in a Harden SOI SRAM显示文摘In order to deepen the understanding of the difference between 0 ! 1 and 1 ! 0 sinle event upset (SEU)cross-section in a novel active delay element (ADE) SRAM (Static Random Access Memory) cell, the irradiationwas carried out at Heavy Ion Research Facility in Lanzhou (HIRFL). Using the 86Kr26+ ions irradiated the deviceunder test (DUT) adopted partially depleted (PD) silicon of insulator (SOI) technology. The feature size of DUTfabricated by institute of microelectronic (IME) was 180 nm. The schematic diagram of SEU harden ADE-SRAMcell is shown in Fig. 1. The ADE is essentially a NMOS connected in only one of the feedback paths between thetwo inventors of the memory cell. It plays a role as switching transistor. Except during a write operation, whenthe switch transistor is turned on (so as not to compromise the write speed), the off-ADE provides a much greaterRC delay between the two inventors of the memory cell to achieve much improved SEU hardness[1]. | Wang Bin Liu Jie Liu Tianqi Yang Zhenlei Gu Song Ye Bing | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 8 | Diverse synthesis of the C ring fragment of bryostatins via Zn/Cu-promoted conjugate addition of α-hydroxy iodide with enone显示文摘A convergent approach to 1,5-hydroxy ketones,the general precursors for constructing the C ring of bryostatins,has been developed via a Zn/Cu-promoted conjugate addition of a-hydroxy iodides with enones.The reaction leads to direct formation of the C21-C22 bond and tolerates diverse functionalities at the C17-,C18-and C24-positions.The approach also enables a more concise synthesis of the known C ring intermediate(10 longest linear steps and 14 total steps),in contrast to its previous synthesis(17 longest linear steps and 22 total steps) in our total synthesis of bryostatin 8. | Zhiwen Chu Ruiqi Tong Yufan Yang Xuanyi Song Tian bao Hu Yu Fan Chen Zhao Lu Gao Zhenlei Song | 2021 | Chinese Chemical Letters2021，32，1： | 0 |
| 9 | An orientation-dependent creep life evaluation method for nickel-based single crystal superalloys显示文摘This paper aims to propose a creep life evaluation method considering the effect of crystallographic orientation.First,the maximum Schmid factor of{111}〈112〉and the corresponding lattice rotation angle were introduced to form an“orientation factor”.Then the equivalent stress was calculated by multiplying this factor and the nominal stress.Latterly,the Larson-Miller Parameter(LMP)method was adopted as the rupture life evaluation criteria,in which the input variable was the equivalent stress instead of the nominal stress.All the predictions showed high accuracy when the proposed method was applied to Mar-M247,SC7-14,CMSX-2,Alloy454,CMSX-4 and DD6.Finally,the applicable temperature ranges of the orientation-dependent method(using equivalent stress)and the traditional LMP method(using nominal stress)were discussed.The results show that only the Orientation-Dependent(OD)method is reliable at intermediate temperatures(760–850°C)because the orientation has significant effect on the stress rupture life,while the influence of orientation is considerably reduced at high temperatures.Both methods provide precise predictions in this situation,and the LMP method should be favored since it is much easier to implement. | Duoqi SHI Tianxiao SUI Zhenlei LI Xiaoguang YANG | 2022 | Chinese Journal of Aeronautics2022，35，1： | 0 |
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